SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4f7h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VW1_D_CVID301_1
(PUTATIVE REGULATORY
PROTEIN)		 4f7h FERMITIN FAMILY
HOMOLOG 2
(Homo
sapiens) 		3 / 3 TYR A 485
MET A 421
LEU A 456
 None
 0.99A 3vw1D-4f7hA:
undetectable		 3vw1D-4f7hA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFG_C_QMRC1214_1
(CAPITELLA TELETA
ACHBP)		 4f7h FERMITIN FAMILY
HOMOLOG 2
(Homo
sapiens) 		4 / 8 TYR A 395
CYH A 397
ILE A 441
ILE A 404
 None
 1.04A 4afgD-4f7hA:
undetectable
4afgE-4f7hA:
undetectable		 4afgD-4f7hA:
22.22
4afgE-4f7hA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPU_C_IPHC101_0
(INSULIN, CHAIN A
INSULIN, CHAIN B)		 4f7h FERMITIN FAMILY
HOMOLOG 2
(Homo
sapiens) 		4 / 6 CYH A 471
LEU A 456
CYH A 426
LEU A 443
 None
 1.08A 5hpuC-4f7hA:
undetectable
5hpuD-4f7hA:
undetectable		 5hpuC-4f7hA:
10.94
5hpuD-4f7hA:
10.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_A_ACTA803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 4f7h FERMITIN FAMILY
HOMOLOG 2
(Homo
sapiens) 		4 / 4 GLU A 427
PRO A 446
ILE A 445
LEU A 444
 None
 0.94A 5m45A-4f7hA:
undetectable		 5m45A-4f7hA:
11.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_D_ACTD803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 4f7h FERMITIN FAMILY
HOMOLOG 2
(Homo
sapiens) 		4 / 4 GLU A 427
PRO A 446
ILE A 445
LEU A 444
 None
 0.98A 5m45D-4f7hA:
undetectable		 5m45D-4f7hA:
11.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_G_ACTG803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 4f7h FERMITIN FAMILY
HOMOLOG 2
(Homo
sapiens) 		4 / 4 GLU A 427
PRO A 446
ILE A 445
LEU A 444
 None
 0.92A 5m45G-4f7hA:
undetectable		 5m45G-4f7hA:
11.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_J_ACTJ803_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 4f7h FERMITIN FAMILY
HOMOLOG 2
(Homo
sapiens) 		4 / 4 GLU A 427
PRO A 446
ILE A 445
LEU A 444
 None
 1.03A 5m45J-4f7hA:
undetectable		 5m45J-4f7hA:
11.87