SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4f7k'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FKB_A_RAPA108_1
(FK506 BINDING
PROTEIN)		 4f7k LACCASE
(uncultured
bacterium) 		5 / 12 ASP A 154
GLN A 242
VAL A 231
ILE A 257
ILE A 156
 None
 1.12A 1fkbA-4f7kA:
undetectable		 1fkbA-4f7kA:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_A_SAMA301_1
(HEMK PROTEIN)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 THR A 369
GLY A 426
ASP A 216
ALA A 429
 None
 0.73A 1sg9A-4f7kA:
undetectable		 1sg9A-4f7kA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_C_ZMRC3478_1
(NEURAMINIDASE)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 8 SER A  79
SER A 125
ASN A  73
GLN A  74
 None
 1.07A 2cmlC-4f7kA:
undetectable		 2cmlC-4f7kA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A  82
HIS A  84
HIS A 376
HIS A 378
 None
 0.29A 2fqeA-4f7kA:
34.5		 2fqeA-4f7kA:
27.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQE_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A 376
HIS A 378
HIS A  82
HIS A  84
 None
 0.80A 2fqeA-4f7kA:
34.5		 2fqeA-4f7kA:
27.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A  82
HIS A  84
HIS A 376
HIS A 378
 None
 0.39A 2fqfA-4f7kA:
34.3		 2fqfA-4f7kA:
27.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQF_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A 376
HIS A 378
HIS A  82
HIS A  84
 None
 0.82A 2fqfA-4f7kA:
34.3		 2fqfA-4f7kA:
27.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A  82
HIS A  84
HIS A 376
HIS A 378
 None
 0.47A 2fqgA-4f7kA:
34.4		 2fqgA-4f7kA:
27.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FQG_A_CUA603_0
(BLUE COPPER OXIDASE
CUEO)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A 376
HIS A 378
HIS A  82
HIS A  84
 None
 0.86A 2fqgA-4f7kA:
34.4		 2fqgA-4f7kA:
27.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBO_A_CAMA442_0
(CYTOCHROME P450-CAM)		 4f7k LACCASE
(uncultured
bacterium) 		5 / 10 VAL A 285
VAL A 200
ASP A 260
ILE A 262
VAL A 226
 None
 1.45A 2qboA-4f7kA:
undetectable		 2qboA-4f7kA:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_A_SVRA508_1
(PHOSPHOLIPASE A2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 5 VAL A 400
GLN A 253
PHE A 371
ARG A 395
 None
 1.32A 3bjwE-4f7kA:
undetectable		 3bjwE-4f7kA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC505_2
(PHOSPHOLIPASE A2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 5 VAL A 400
GLN A 253
PHE A 371
ARG A 395
 None
 1.36A 3bjwH-4f7kA:
undetectable		 3bjwH-4f7kA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_C_ADNC438_2
(ADENOSYLHOMOCYSTEINA
SE)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 5 GLN A 100
THR A  99
HIS A 376
HIS A 126
 None
 1.40A 3g1uC-4f7kA:
undetectable		 3g1uC-4f7kA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS4_A_AZMA703_1
(CARBONIC ANHYDRASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 5 HIS A  84
TRP A  83
HIS A 126
ASP A  93
 None
 1.24A 3hs4A-4f7kA:
0.0		 3hs4A-4f7kA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXE_A_TORA262_1
(CARBONIC ANHYDRASE 1)		 4f7k LACCASE
(uncultured
bacterium) 		5 / 12 HIS A 376
PHE A 113
HIS A 381
VAL A 143
HIS A  84
 None
 1.38A 3lxeA-4f7kA:
undetectable		 3lxeA-4f7kA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXE_B_TORB262_1
(CARBONIC ANHYDRASE 1)		 4f7k LACCASE
(uncultured
bacterium) 		5 / 12 HIS A 376
PHE A 113
HIS A 381
VAL A 143
HIS A  84
 None
 1.37A 3lxeB-4f7kA:
undetectable		 3lxeB-4f7kA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MJR_D_AC2D601_1
(DEOXYCYTIDINE KINASE)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 8 GLU A 145
PHE A 121
ARG A 207
ASP A 256
 None
 1.11A 3mjrD-4f7kA:
undetectable		 3mjrD-4f7kA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA604_0
(LACCASE-1)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A  82
HIS A  84
HIS A 376
HIS A 378
 None
 0.41A 3qpkA-4f7kA:
27.7		 3qpkA-4f7kA:
27.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_A_CUA604_0
(LACCASE-1)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A 376
HIS A 378
HIS A  82
HIS A  84
 None
 0.85A 3qpkA-4f7kA:
27.7		 3qpkA-4f7kA:
27.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB604_0
(LACCASE-1)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A  82
HIS A  84
HIS A 376
HIS A 378
 None
 0.37A 3qpkB-4f7kA:
27.8		 3qpkB-4f7kA:
27.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QPK_B_CUB604_0
(LACCASE-1)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A 376
HIS A 378
HIS A  82
HIS A  84
 None
 0.83A 3qpkB-4f7kA:
27.8		 3qpkB-4f7kA:
27.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_A_SAMA258_0
(PUTATIVE
METHYLTRANSFERASE)		 4f7k LACCASE
(uncultured
bacterium) 		5 / 12 ARG A  62
GLY A  64
GLU A 144
ALA A 118
ASN A 303
 None
 1.27A 3sxjA-4f7kA:
undetectable		 3sxjA-4f7kA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_B_SAMB258_0
(PUTATIVE
METHYLTRANSFERASE)		 4f7k LACCASE
(uncultured
bacterium) 		5 / 12 ARG A  62
GLY A  64
GLU A 144
ALA A 118
ASN A 303
 None
 1.27A 3sxjB-4f7kA:
undetectable		 3sxjB-4f7kA:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VLN_A_ASCA904_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 6 PHE A 219
ARG A 217
LEU A 249
PRO A 251
 None
 1.35A 3vlnA-4f7kA:
undetectable		 3vlnA-4f7kA:
19.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_A_ZPCA1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 7 ILE A 297
PHE A 244
HIS A 153
VAL A 194
 None
 0.86A 4a97A-4f7kA:
2.9		 4a97A-4f7kA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_D_ZPCD1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 7 ILE A 297
PHE A 244
HIS A 153
VAL A 194
 None
 0.78A 4a97D-4f7kA:
2.9		 4a97D-4f7kA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_I_ZPCI1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 6 ILE A 297
PHE A 244
HIS A 153
VAL A 194
 None
 0.85A 4a97I-4f7kA:
undetectable		 4a97I-4f7kA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1004_0
(BLUE COPPER OXIDASE
CUEO)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A  82
HIS A  84
HIS A 376
HIS A 378
 None
 0.45A 4ef3A-4f7kA:
34.1		 4ef3A-4f7kA:
27.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EF3_A_CUA1004_0
(BLUE COPPER OXIDASE
CUEO)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A 376
HIS A 378
HIS A  82
HIS A  84
 None
 0.86A 4ef3A-4f7kA:
34.1		 4ef3A-4f7kA:
27.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEU_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 8 ASP A 150
ASP A 152
ASN A 289
ASP A 260
 None
 1.19A 4feuF-4f7kA:
undetectable		 4feuF-4f7kA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 7 ASP A 150
ASP A 152
ASN A 289
ASP A 260
 None
 1.11A 4fevB-4f7kA:
undetectable		 4fevB-4f7kA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 7 ASP A 150
ASP A 152
ASN A 289
ASP A 260
 None
 1.20A 4fevD-4f7kA:
undetectable		 4fevD-4f7kA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEV_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 7 ASP A 150
ASP A 152
ASN A 289
ASP A 260
 None
 1.20A 4fevF-4f7kA:
undetectable		 4fevF-4f7kA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 7 ASP A 150
ASP A 152
ASN A 289
ASP A 260
 None
 1.13A 4fewB-4f7kA:
undetectable		 4fewB-4f7kA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 8 ASP A 150
ASP A 152
ASN A 289
ASP A 260
 None
 1.20A 4fewD-4f7kA:
undetectable		 4fewD-4f7kA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEW_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 8 ASP A 150
ASP A 152
ASN A 289
ASP A 260
 None
 1.19A 4fewF-4f7kA:
undetectable		 4fewF-4f7kA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FEX_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 7 ASP A 150
ASP A 152
ASN A 289
ASP A 260
 None
 1.20A 4fexB-4f7kA:
undetectable		 4fexB-4f7kA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_C_CLQC303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 4f7k LACCASE
(uncultured
bacterium) 		4 / 8 GLY A  94
VAL A  95
HIS A 126
PHE A  50
 None
 0.97A 4fglD-4f7kA:
undetectable		 4fglD-4f7kA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G19_A_ACTA304_0
(GLUTATHIONE
TRANSFERASE GTE1)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 5 ALA A 214
ILE A 218
LEU A 425
ASN A 212
 None
 0.95A 4g19A-4f7kA:
undetectable		 4g19A-4f7kA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_B_KANB301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 8 ASP A 150
ASP A 152
ASN A 289
ASP A 260
 None
 1.19A 4gkhB-4f7kA:
undetectable		 4gkhB-4f7kA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_D_KAND301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 8 ASP A 150
ASP A 152
ASN A 289
ASP A 260
 None
 1.13A 4gkhD-4f7kA:
undetectable		 4gkhD-4f7kA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_F_KANF301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 8 ASP A 150
ASP A 152
ASN A 289
ASP A 260
 None
 1.17A 4gkhF-4f7kA:
undetectable		 4gkhF-4f7kA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_G_KANG301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 7 ASP A 150
ASP A 152
ASN A 289
ASP A 260
 None
 1.20A 4gkhG-4f7kA:
undetectable		 4gkhG-4f7kA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKH_J_KANJ301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 6 ASP A 150
ASP A 152
ASN A 289
ASP A 260
 None
 1.12A 4gkhJ-4f7kA:
undetectable		 4gkhJ-4f7kA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_A_KANA301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 8 ASP A 150
ASP A 152
ASN A 289
ASP A 260
 None
 1.21A 4gkiA-4f7kA:
undetectable		 4gkiA-4f7kA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GKI_C_KANC301_1
(AMINOGLYCOSIDE
3'-PHOSPHOTRANSFERAS
E APHA1-IAB)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 8 ASP A 150
ASP A 152
ASN A 289
ASP A 260
 None
 1.20A 4gkiC-4f7kA:
undetectable		 4gkiC-4f7kA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_B_SAMB601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 4f7k LACCASE
(uncultured
bacterium) 		5 / 12 ALA A 429
GLY A 426
ILE A 218
GLY A 374
LEU A 399
 None
 1.23A 4n48B-4f7kA:
undetectable		 4n48B-4f7kA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5I_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 4f7k LACCASE
(uncultured
bacterium) 		3 / 3 ASP A 388
ARG A 364
ARG A 362
 None
 0.70A 4x5iA-4f7kA:
undetectable		 4x5iA-4f7kA:
18.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQG_A_AG2A505_1
(HOMOSPERMIDINE
SYNTHASE)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 8 ARG A 128
VAL A 213
ASP A 161
ASP A 160
 None
 0.90A 4xqgA-4f7kA:
undetectable		 4xqgA-4f7kA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQG_B_AG2B505_1
(HOMOSPERMIDINE
SYNTHASE)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 8 ARG A 128
VAL A 213
ASP A 161
ASP A 160
 None
 0.91A 4xqgB-4f7kA:
undetectable		 4xqgB-4f7kA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_A_STRA604_1
(CYTOCHROME P450
21-HYDROXYLASE)		 4f7k LACCASE
(uncultured
bacterium) 		5 / 12 VAL A 261
ILE A 267
GLY A 268
VAL A 221
LEU A 210
 None
None
GOL  A 501 ( 4.0A)
None
None
 1.11A 4y8wA-4f7kA:
undetectable		 4y8wA-4f7kA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_B_STRB603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 4f7k LACCASE
(uncultured
bacterium) 		5 / 12 VAL A 261
ILE A 267
GLY A 268
VAL A 221
LEU A 210
 None
None
GOL  A 501 ( 4.0A)
None
None
 1.11A 4y8wB-4f7kA:
undetectable		 4y8wB-4f7kA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_2_BEZ2801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 LEU A 155
ARG A  60
ILE A 156
ILE A 142
 None
 1.14A 5dzk2-4f7kA:
undetectable
5dzkM-4f7kA:
undetectable
5dzkN-4f7kA:
undetectable		 5dzk2-4f7kA:
0.78
5dzkM-4f7kA:
18.18
5dzkN-4f7kA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_V_BEZV801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 ILE A 156
ILE A 142
ARG A  60
LEU A 155
 None
 1.37A 5dzkh-4f7kA:
undetectable
5dzkn-4f7kA:
undetectable
5dzkv-4f7kA:
undetectable		 5dzkh-4f7kA:
18.18
5dzkn-4f7kA:
18.18
5dzkv-4f7kA:
0.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_B_FOLB201_1
(DIHYDROFOLATE
REDUCTASE)		 4f7k LACCASE
(uncultured
bacterium) 		3 / 3 ASP A 388
ARG A 364
ARG A 362
 None
 0.87A 5eajB-4f7kA:
undetectable		 5eajB-4f7kA:
15.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HG0_B_SAMB301_0
(PANTOTHENATE
SYNTHETASE)		 4f7k LACCASE
(uncultured
bacterium) 		5 / 12 HIS A 373
GLY A 403
ASP A 368
THR A 405
LEU A 365
 None
 1.05A 5hg0B-4f7kA:
undetectable		 5hg0B-4f7kA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_D_FK5D201_1
(FK506-BINDING
PROTEIN 1)		 4f7k LACCASE
(uncultured
bacterium) 		5 / 11 ASP A 154
VAL A 231
ILE A 257
ILE A 156
ILE A 157
 None
 1.18A 5hw8D-4f7kA:
undetectable		 5hw8D-4f7kA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA502_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		5 / 6 HIS A  82
HIS A  84
TRP A 122
HIS A 124
HIS A 376
 None
 0.45A 5mejA-4f7kA:
8.0		 5mejA-4f7kA:
29.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA503_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A  82
HIS A  84
HIS A 376
HIS A 378
 None
 0.38A 5mejA-4f7kA:
8.0		 5mejA-4f7kA:
29.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEJ_A_CUA503_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A 376
HIS A 378
HIS A  82
HIS A  84
 None
 0.80A 5mejA-4f7kA:
8.0		 5mejA-4f7kA:
29.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA502_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		5 / 6 HIS A  82
HIS A  84
TRP A 122
HIS A 124
HIS A 376
 None
 0.46A 5mewA-4f7kA:
32.1		 5mewA-4f7kA:
29.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA503_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A  82
HIS A  84
HIS A 376
HIS A 378
 None
 0.38A 5mewA-4f7kA:
32.1		 5mewA-4f7kA:
29.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MEW_A_CUA503_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A 376
HIS A 378
HIS A  82
HIS A  84
 None
 0.80A 5mewA-4f7kA:
32.1		 5mewA-4f7kA:
29.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA502_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		5 / 6 HIS A  82
HIS A  84
TRP A 122
HIS A 124
HIS A 376
 None
 0.47A 5mhuA-4f7kA:
32.2		 5mhuA-4f7kA:
29.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA503_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A  82
HIS A  84
HIS A 376
HIS A 378
 None
 0.39A 5mhuA-4f7kA:
32.2		 5mhuA-4f7kA:
29.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHU_A_CUA503_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A 376
HIS A 378
HIS A  82
HIS A  84
 None
 0.80A 5mhuA-4f7kA:
32.2		 5mhuA-4f7kA:
29.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA502_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		5 / 6 HIS A  82
HIS A  84
TRP A 122
HIS A 124
HIS A 376
 None
 0.48A 5mhvA-4f7kA:
32.2		 5mhvA-4f7kA:
29.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA503_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A  82
HIS A  84
HIS A 376
HIS A 378
 None
 0.39A 5mhvA-4f7kA:
32.2		 5mhvA-4f7kA:
29.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHV_A_CUA503_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A 376
HIS A 378
HIS A  82
HIS A  84
 None
 0.81A 5mhvA-4f7kA:
32.2		 5mhvA-4f7kA:
29.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA602_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 5 HIS A  82
HIS A  84
TRP A 122
HIS A 124
 None
 0.38A 5mhwA-4f7kA:
32.1		 5mhwA-4f7kA:
27.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA603_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A  82
HIS A  84
HIS A 376
HIS A 378
 None
 0.39A 5mhwA-4f7kA:
32.1		 5mhwA-4f7kA:
27.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHW_A_CUA603_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A 376
HIS A 378
HIS A  82
HIS A  84
 None
 0.81A 5mhwA-4f7kA:
32.1		 5mhwA-4f7kA:
27.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA602_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 5 HIS A  82
HIS A  84
TRP A 122
HIS A 124
 None
 0.38A 5mhxA-4f7kA:
32.1		 5mhxA-4f7kA:
27.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA603_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A  82
HIS A  84
HIS A 376
HIS A 378
 None
 0.39A 5mhxA-4f7kA:
32.1		 5mhxA-4f7kA:
27.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHX_A_CUA603_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A 376
HIS A 378
HIS A  82
HIS A  84
 None
 0.81A 5mhxA-4f7kA:
32.1		 5mhxA-4f7kA:
27.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA602_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 5 HIS A  82
HIS A  84
TRP A 122
HIS A 124
 None
 0.38A 5mhyA-4f7kA:
32.0		 5mhyA-4f7kA:
27.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA603_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A  82
HIS A  84
HIS A 376
HIS A 378
 None
 0.39A 5mhyA-4f7kA:
32.1		 5mhyA-4f7kA:
27.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHY_A_CUA603_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A 376
HIS A 378
HIS A  82
HIS A  84
 None
 0.81A 5mhyA-4f7kA:
32.1		 5mhyA-4f7kA:
27.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA602_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 5 HIS A  82
HIS A  84
TRP A 122
HIS A 124
 None
 0.39A 5mhzA-4f7kA:
32.1		 5mhzA-4f7kA:
27.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA603_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A  82
HIS A  84
HIS A 376
HIS A 378
 None
 0.39A 5mhzA-4f7kA:
32.1		 5mhzA-4f7kA:
27.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MHZ_A_CUA603_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A 376
HIS A 378
HIS A  82
HIS A  84
 None
 0.81A 5mhzA-4f7kA:
32.1		 5mhzA-4f7kA:
27.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA602_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 5 HIS A  82
HIS A  84
TRP A 122
HIS A 124
 None
 0.39A 5mi1A-4f7kA:
32.2		 5mi1A-4f7kA:
27.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA603_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A  82
HIS A  84
HIS A 376
HIS A 378
 None
 0.39A 5mi1A-4f7kA:
32.1		 5mi1A-4f7kA:
27.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI1_A_CUA603_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A 376
HIS A 378
HIS A  82
HIS A  84
 None
 0.81A 5mi1A-4f7kA:
32.1		 5mi1A-4f7kA:
27.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA602_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 5 HIS A  82
HIS A  84
TRP A 122
HIS A 124
 None
 0.39A 5mi2A-4f7kA:
32.1		 5mi2A-4f7kA:
27.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA603_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A  82
HIS A  84
HIS A 376
HIS A 378
 None
 0.39A 5mi2A-4f7kA:
32.2		 5mi2A-4f7kA:
27.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MI2_A_CUA603_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A 376
HIS A 378
HIS A  82
HIS A  84
 None
 0.81A 5mi2A-4f7kA:
32.2		 5mi2A-4f7kA:
27.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA602_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 5 HIS A  82
HIS A  84
TRP A 122
HIS A 124
 None
 0.38A 5miaA-4f7kA:
32.1		 5miaA-4f7kA:
27.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA603_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A  82
HIS A  84
HIS A 376
HIS A 378
 None
 0.39A 5miaA-4f7kA:
32.1		 5miaA-4f7kA:
27.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIA_A_CUA603_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A 376
HIS A 378
HIS A  82
HIS A  84
 None
 0.81A 5miaA-4f7kA:
32.1		 5miaA-4f7kA:
27.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA602_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 5 HIS A  82
HIS A  84
TRP A 122
HIS A 124
 None
 0.38A 5mibA-4f7kA:
32.1		 5mibA-4f7kA:
27.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA603_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A  82
HIS A  84
HIS A 376
HIS A 378
 None
 0.39A 5mibA-4f7kA:
32.1		 5mibA-4f7kA:
27.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIB_A_CUA603_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A 376
HIS A 378
HIS A  82
HIS A  84
 None
 0.81A 5mibA-4f7kA:
32.1		 5mibA-4f7kA:
27.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA602_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 5 HIS A  82
HIS A  84
TRP A 122
HIS A 124
 None
 0.39A 5micA-4f7kA:
32.2		 5micA-4f7kA:
27.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA603_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A  82
HIS A  84
HIS A 376
HIS A 378
 None
 0.39A 5micA-4f7kA:
32.1		 5micA-4f7kA:
27.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIC_A_CUA603_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A 376
HIS A 378
HIS A  82
HIS A  84
 None
 0.81A 5micA-4f7kA:
32.1		 5micA-4f7kA:
27.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA602_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 5 HIS A  82
HIS A  84
TRP A 122
HIS A 124
 None
 0.39A 5midA-4f7kA:
32.2		 5midA-4f7kA:
27.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA603_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A  82
HIS A  84
HIS A 376
HIS A 378
 None
 0.39A 5midA-4f7kA:
32.1		 5midA-4f7kA:
27.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MID_A_CUA603_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A 376
HIS A 378
HIS A  82
HIS A  84
 None
 0.81A 5midA-4f7kA:
32.1		 5midA-4f7kA:
27.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA602_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 5 HIS A  82
HIS A  84
TRP A 122
HIS A 124
 None
 0.39A 5mieA-4f7kA:
32.2		 5mieA-4f7kA:
27.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA603_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A  82
HIS A  84
HIS A 376
HIS A 378
 None
 0.39A 5mieA-4f7kA:
32.1		 5mieA-4f7kA:
27.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIE_A_CUA603_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A 376
HIS A 378
HIS A  82
HIS A  84
 None
 0.81A 5mieA-4f7kA:
32.1		 5mieA-4f7kA:
27.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA602_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 5 HIS A  82
HIS A  84
TRP A 122
HIS A 124
 None
 0.39A 5migA-4f7kA:
32.1		 5migA-4f7kA:
27.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA603_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A  82
HIS A  84
HIS A 376
HIS A 378
 None
 0.38A 5migA-4f7kA:
32.1		 5migA-4f7kA:
27.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MIG_A_CUA603_0
(LACCASE 2)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 4 HIS A 376
HIS A 378
HIS A  82
HIS A  84
 None
 0.80A 5migA-4f7kA:
32.1		 5migA-4f7kA:
27.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_1
(REGULATORY PROTEIN
TETR)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 8 GLY A 389
ARG A 364
VAL A 385
ASP A 407
 None
 1.07A 5vlmA-4f7kA:
undetectable		 5vlmA-4f7kA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_D_HFGD1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))		 4f7k LACCASE
(uncultured
bacterium) 		5 / 12 LEU A 425
PHE A 219
PRO A 251
TRP A 122
GLY A 139
 None
 1.32A 5xiqD-4f7kA:
undetectable		 5xiqD-4f7kA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C71_B_NCTB501_1
(AMINE OXIDASE)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 8 TRP A 162
LEU A 280
TYR A 278
ASN A 188
 None
 1.16A 6c71B-4f7kA:
undetectable		 6c71B-4f7kA:
11.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_1
(CYTOCHROME P450 1A1)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 7 ASN A  73
GLY A  52
VAL A  26
LEU A  28
 None
 0.83A 6dwnB-4f7kA:
undetectable		 6dwnB-4f7kA:
10.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_C_ADNC502_0
(ADENOSYLHOMOCYSTEINA
SE)		 4f7k LACCASE
(uncultured
bacterium) 		5 / 12 HIS A 378
GLN A 100
THR A  99
HIS A 421
HIS A 126
 None
 1.41A 6exiC-4f7kA:
undetectable		 6exiC-4f7kA:
12.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 7 GLY A 119
THR A 120
PHE A 121
ARG A 395
 None
 0.79A 6jnhA-4f7kA:
undetectable		 6jnhA-4f7kA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_A_AM2A301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 8 ASP A 396
ARG A 395
HIS A 381
GLU A 384
 None
 1.09A 6mn4A-4f7kA:
undetectable		 6mn4A-4f7kA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_B_AM2B301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 8 ASP A 396
ARG A 395
HIS A 381
GLU A 384
 None
 0.94A 6mn4B-4f7kA:
undetectable		 6mn4B-4f7kA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_C_AM2C301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 8 ARG A  87
HIS A 380
ASP A 117
GLU A 304
 None
 1.30A 6mn4C-4f7kA:
undetectable		 6mn4C-4f7kA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN4_C_AM2C301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 4f7k LACCASE
(uncultured
bacterium) 		4 / 8 ASP A 396
ARG A 395
HIS A 381
GLU A 384
 None
 1.10A 6mn4C-4f7kA:
undetectable		 6mn4C-4f7kA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NQA_K_SAMK500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE,
H3 LYSINE-79
SPECIFIC)		 4f7k LACCASE
(uncultured
bacterium) 		5 / 10 GLY A 225
GLY A 268
VAL A 285
GLU A 224
PHE A 244
 None
GOL  A 501 ( 4.0A)
None
GOL  A 501 (-3.9A)
None
 1.43A 6nqaK-4f7kA:
undetectable		 6nqaK-4f7kA:
20.82