SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4f82'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H4O_A_BEZA1162_0
(PEROXIREDOXIN 5)		 4f82 THIOREDOXIN
REDUCTASE
(Burkholderia
cenocepacia) 		5 / 10 PRO A  48
THR A  52
PRO A  53
CYH A  55
ARG A 133
 None
 0.18A 1h4oA-4f82A:
27.5
1h4oB-4f82A:
27.7		 1h4oA-4f82A:
42.05
1h4oB-4f82A:
42.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H4O_A_BEZA1162_0
(PEROXIREDOXIN 5)		 4f82 THIOREDOXIN
REDUCTASE
(Burkholderia
cenocepacia) 		5 / 10 THR A  52
PRO A  53
CYH A  55
LEU A 122
ARG A 133
 None
 0.67A 1h4oA-4f82A:
27.5
1h4oB-4f82A:
27.7		 1h4oA-4f82A:
42.05
1h4oB-4f82A:
42.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)		 4f82 THIOREDOXIN
REDUCTASE
(Burkholderia
cenocepacia) 		5 / 8 PRO A  48
THR A  52
PRO A  53
CYH A  55
ARG A 133
 None
 0.16A 1h4oB-4f82A:
27.7		 1h4oB-4f82A:
42.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H4O_C_BEZC1162_0
(PEROXIREDOXIN 5)		 4f82 THIOREDOXIN
REDUCTASE
(Burkholderia
cenocepacia) 		5 / 9 PRO A  48
THR A  52
PRO A  53
CYH A  55
ARG A 133
 None
 0.15A 1h4oC-4f82A:
27.4
1h4oD-4f82A:
27.4		 1h4oC-4f82A:
42.05
1h4oD-4f82A:
42.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H4O_D_BEZD1162_0
(PEROXIREDOXIN 5)		 4f82 THIOREDOXIN
REDUCTASE
(Burkholderia
cenocepacia) 		5 / 9 PRO A  48
THR A  52
PRO A  53
CYH A  55
ARG A 133
 None
 0.16A 1h4oD-4f82A:
27.4		 1h4oD-4f82A:
42.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H4O_D_BEZD1162_0
(PEROXIREDOXIN 5)		 4f82 THIOREDOXIN
REDUCTASE
(Burkholderia
cenocepacia) 		5 / 9 THR A  52
PRO A  53
CYH A  55
LEU A 122
ARG A 133
 None
 0.71A 1h4oD-4f82A:
27.4		 1h4oD-4f82A:
42.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H4O_E_BEZE1162_0
(PEROXIREDOXIN 5)		 4f82 THIOREDOXIN
REDUCTASE
(Burkholderia
cenocepacia) 		5 / 9 PRO A  48
THR A  52
PRO A  53
CYH A  55
ARG A 133
 None
 0.17A 1h4oE-4f82A:
27.5
1h4oF-4f82A:
27.5		 1h4oE-4f82A:
42.05
1h4oF-4f82A:
42.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H4O_F_BEZF1162_0
(PEROXIREDOXIN 5)		 4f82 THIOREDOXIN
REDUCTASE
(Burkholderia
cenocepacia) 		5 / 9 PRO A  48
THR A  52
PRO A  53
CYH A  55
ARG A 133
 None
 0.14A 1h4oF-4f82A:
27.5		 1h4oF-4f82A:
42.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H4O_F_BEZF1162_0
(PEROXIREDOXIN 5)		 4f82 THIOREDOXIN
REDUCTASE
(Burkholderia
cenocepacia) 		5 / 9 THR A  52
PRO A  53
CYH A  55
LEU A 122
ARG A 133
 None
 0.70A 1h4oF-4f82A:
27.5		 1h4oF-4f82A:
42.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H4O_G_BEZG1162_0
(PEROXIREDOXIN 5)		 4f82 THIOREDOXIN
REDUCTASE
(Burkholderia
cenocepacia) 		5 / 8 PRO A  48
THR A  52
PRO A  53
CYH A  55
ARG A 133
 None
 0.18A 1h4oG-4f82A:
27.4		 1h4oG-4f82A:
42.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H4O_G_BEZG1162_0
(PEROXIREDOXIN 5)		 4f82 THIOREDOXIN
REDUCTASE
(Burkholderia
cenocepacia) 		5 / 8 THR A  52
PRO A  53
CYH A  55
LEU A 122
ARG A 133
 None
 0.68A 1h4oG-4f82A:
27.4		 1h4oG-4f82A:
42.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H4O_H_BEZH1162_0
(PEROXIREDOXIN 5)		 4f82 THIOREDOXIN
REDUCTASE
(Burkholderia
cenocepacia) 		5 / 9 PRO A  48
THR A  52
PRO A  53
CYH A  55
ARG A 133
 None
 0.13A 1h4oH-4f82A:
27.8		 1h4oH-4f82A:
42.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H4O_H_BEZH1162_0
(PEROXIREDOXIN 5)		 4f82 THIOREDOXIN
REDUCTASE
(Burkholderia
cenocepacia) 		5 / 9 THR A  52
PRO A  53
CYH A  55
LEU A 122
ARG A 133
 None
 0.66A 1h4oH-4f82A:
27.8		 1h4oH-4f82A:
42.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HD2_A_BEZA201_0
(PEROXIREDOXIN 5
RESIDUES 54-214)		 4f82 THIOREDOXIN
REDUCTASE
(Burkholderia
cenocepacia) 		5 / 9 PRO A  48
THR A  52
PRO A  53
CYH A  55
ARG A 133
 None
 0.14A 1hd2A-4f82A:
27.3		 1hd2A-4f82A:
42.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1HD2_A_BEZA201_0
(PEROXIREDOXIN 5
RESIDUES 54-214)		 4f82 THIOREDOXIN
REDUCTASE
(Burkholderia
cenocepacia) 		5 / 9 THR A  52
PRO A  53
CYH A  55
LEU A 122
ARG A 133
 None
 0.65A 1hd2A-4f82A:
27.3		 1hd2A-4f82A:
42.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_4
(HIV-1 PROTEASE)		 4f82 THIOREDOXIN
REDUCTASE
(Burkholderia
cenocepacia) 		4 / 4 GLY A  74
ASP A  76
GLY A 140
THR A 145
 None
 1.07A 1hxbB-4f82A:
undetectable		 1hxbB-4f82A:
17.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)		 4f82 THIOREDOXIN
REDUCTASE
(Burkholderia
cenocepacia) 		5 / 8 PRO A  48
THR A  52
PRO A  53
CYH A  55
ARG A 133
 None
 0.22A 1oc3A-4f82A:
27.7		 1oc3A-4f82A:
43.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OC3_B_BEZB201_0
(PEROXIREDOXIN 5)		 4f82 THIOREDOXIN
REDUCTASE
(Burkholderia
cenocepacia) 		5 / 9 PRO A  48
THR A  52
PRO A  53
CYH A  55
ARG A 133
 None
 0.16A 1oc3B-4f82A:
27.3		 1oc3B-4f82A:
43.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OC3_B_BEZB201_0
(PEROXIREDOXIN 5)		 4f82 THIOREDOXIN
REDUCTASE
(Burkholderia
cenocepacia) 		5 / 9 THR A  52
PRO A  53
CYH A  55
LEU A 122
ARG A 133
 None
 0.70A 1oc3B-4f82A:
27.3		 1oc3B-4f82A:
43.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T3R_A_017A1200_2
(PROTEASE RETROPEPSIN)		 4f82 THIOREDOXIN
REDUCTASE
(Burkholderia
cenocepacia) 		6 / 11 LEU A  13
ALA A 111
VAL A  83
GLY A 117
ILE A   2
VAL A  81
 None
 1.11A 1t3rB-4f82A:
undetectable		 1t3rB-4f82A:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEO_A_017A402_1
(PROTEASE)		 4f82 THIOREDOXIN
REDUCTASE
(Burkholderia
cenocepacia) 		6 / 12 LEU A  13
ALA A 111
VAL A  83
GLY A 117
ILE A   2
VAL A  81
 None
 1.17A 2ieoA-4f82A:
undetectable		 2ieoA-4f82A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_C_BEZC1222_0
(PEROXIREDOXIN 6)		 4f82 THIOREDOXIN
REDUCTASE
(Burkholderia
cenocepacia) 		4 / 8 PRO A  48
THR A  52
PRO A  53
ARG A 133
 None
 0.54A 2v32C-4f82A:
18.1
2v32D-4f82A:
19.6		 2v32C-4f82A:
22.22
2v32D-4f82A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_C_BEZC1218_0
(PEROXIREDOXIN 6.)		 4f82 THIOREDOXIN
REDUCTASE
(Burkholderia
cenocepacia) 		4 / 8 PRO A  48
THR A  52
PRO A  53
ARG A 133
 None
 0.60A 2v41C-4f82A:
19.4
2v41D-4f82A:
19.6		 2v41C-4f82A:
22.22
2v41D-4f82A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_D_BEZD1222_0
(PEROXIREDOXIN 6.)		 4f82 THIOREDOXIN
REDUCTASE
(Burkholderia
cenocepacia) 		4 / 8 PRO A  48
THR A  52
PRO A  53
ARG A 133
 None
 0.59A 2v41C-4f82A:
19.4
2v41D-4f82A:
19.6		 2v41C-4f82A:
22.22
2v41D-4f82A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_H_BEZH1222_0
(PEROXIREDOXIN 6.)		 4f82 THIOREDOXIN
REDUCTASE
(Burkholderia
cenocepacia) 		4 / 8 PRO A  48
THR A  52
PRO A  53
ARG A 133
 None
 0.57A 2v41G-4f82A:
17.8
2v41H-4f82A:
18.0		 2v41G-4f82A:
22.22
2v41H-4f82A:
22.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VL2_A_BEZA1162_0
(PEROXIREDOXIN-5)		 4f82 THIOREDOXIN
REDUCTASE
(Burkholderia
cenocepacia) 		5 / 10 PRO A  48
THR A  52
PRO A  53
CYH A  55
ARG A 133
 None
 0.25A 2vl2A-4f82A:
27.6
2vl2C-4f82A:
23.0		 2vl2A-4f82A:
43.65
2vl2C-4f82A:
43.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VL2_A_BEZA1162_0
(PEROXIREDOXIN-5)		 4f82 THIOREDOXIN
REDUCTASE
(Burkholderia
cenocepacia) 		5 / 10 THR A  52
PRO A  53
CYH A  55
LEU A 122
ARG A 133
 None
 0.76A 2vl2A-4f82A:
27.6
2vl2C-4f82A:
23.0		 2vl2A-4f82A:
43.65
2vl2C-4f82A:
43.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_2
(PROTEASE)		 4f82 THIOREDOXIN
REDUCTASE
(Burkholderia
cenocepacia) 		5 / 9 ALA A 111
VAL A  83
GLY A 117
ILE A   2
VAL A  81
 None
 1.03A 3ekvB-4f82A:
undetectable		 3ekvB-4f82A:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_2
(HIV-1 PROTEASE)		 4f82 THIOREDOXIN
REDUCTASE
(Burkholderia
cenocepacia) 		4 / 4 GLY A  74
ASP A  76
GLY A 140
THR A 145
 None
 1.04A 3k4vC-4f82A:
undetectable		 3k4vC-4f82A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OY4_B_017B200_1
(HIV-1 PROTEASE)		 4f82 THIOREDOXIN
REDUCTASE
(Burkholderia
cenocepacia) 		6 / 11 LEU A  13
ALA A 111
VAL A  83
GLY A 117
ILE A   2
VAL A  81
 None
 1.15A 3oy4A-4f82A:
undetectable		 3oy4A-4f82A:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AFT_D_QMRD301_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 4f82 THIOREDOXIN
REDUCTASE
(Burkholderia
cenocepacia) 		4 / 8 TYR A  63
VAL A 137
VAL A 143
ILE A  44
 None
 1.15A 4aftD-4f82A:
undetectable
4aftE-4f82A:
undetectable		 4aftD-4f82A:
20.59
4aftE-4f82A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQB_B_017B101_1
(ASPARTYL PROTEASE)		 4f82 THIOREDOXIN
REDUCTASE
(Burkholderia
cenocepacia) 		6 / 12 LEU A  13
ALA A 111
VAL A  83
GLY A 117
ILE A   2
VAL A  81
 None
 1.08A 4dqbA-4f82A:
undetectable		 4dqbA-4f82A:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_1
(ASPARTYL PROTEASE)		 4f82 THIOREDOXIN
REDUCTASE
(Burkholderia
cenocepacia) 		5 / 10 ALA A 111
VAL A  83
GLY A 117
ILE A   2
VAL A  81
 None
 1.09A 4dqcA-4f82A:
undetectable		 4dqcA-4f82A:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQE_B_017B101_1
(ASPARTYL PROTEASE)		 4f82 THIOREDOXIN
REDUCTASE
(Burkholderia
cenocepacia) 		6 / 11 LEU A  13
ALA A 111
VAL A  83
GLY A 117
ILE A   2
VAL A  81
 None
 1.15A 4dqeA-4f82A:
undetectable		 4dqeA-4f82A:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQH_B_017B101_1
(WILD-TYPE HIV-1
PROTEASE DIMER)		 4f82 THIOREDOXIN
REDUCTASE
(Burkholderia
cenocepacia) 		6 / 11 LEU A  13
ALA A 111
VAL A  83
GLY A 117
ILE A   2
VAL A  81
 None
 1.11A 4dqhA-4f82A:
undetectable		 4dqhA-4f82A:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1W_A_017A104_2
(ASPARTYL PROTEASE)		 4f82 THIOREDOXIN
REDUCTASE
(Burkholderia
cenocepacia) 		5 / 10 ALA A 111
VAL A  83
GLY A 117
ILE A   2
VAL A  81
 None
 1.07A 4q1wB-4f82A:
undetectable		 4q1wB-4f82A:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDP_H_EVPH2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B)		 4f82 THIOREDOXIN
REDUCTASE
(Burkholderia
cenocepacia) 		4 / 6 GLU A  15
GLY A 140
ASP A 139
GLY A  39
 None
 0.87A 5cdpA-4f82A:
undetectable
5cdpB-4f82A:
undetectable		 5cdpA-4f82A:
17.47
5cdpB-4f82A:
23.66