SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4f9l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H8S_A_AICA1000_1
(MUTANT AL2 6E7P9G)		 4f9l 20.1 ANTI-BTN3A1
ANTIBODY FRAGMENT
(Mus
musculus) 		6 / 12 TYR D  36
GLN D  89
TYR D  94
PHE D  98
VAL D 168
TRP D 243
 None
 0.74A 1h8sA-4f9lD:
30.2		 1h8sA-4f9lD:
69.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4f9l 20.1 ANTI-BTN3A1
ANTIBODY FRAGMENT
(Mus
musculus) 		4 / 6 LEU D 142
ARG D 171
THR D 218
LEU D 217
 None
 0.96A 1v54A-4f9lD:
undetectable
1v54J-4f9lD:
undetectable		 1v54A-4f9lD:
18.81
1v54J-4f9lD:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4f9l 20.1 ANTI-BTN3A1
ANTIBODY FRAGMENT
(Mus
musculus) 		4 / 7 LEU D 142
ARG D 171
THR D 218
LEU D 217
 None
 0.94A 1v54N-4f9lD:
undetectable
1v54W-4f9lD:
undetectable		 1v54N-4f9lD:
18.81
1v54W-4f9lD:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4f9l 20.1 ANTI-BTN3A1
ANTIBODY FRAGMENT
(Mus
musculus) 		4 / 7 LEU D 142
ARG D 171
THR D 218
LEU D 217
 None
 0.89A 1v55A-4f9lD:
undetectable
1v55J-4f9lD:
undetectable		 1v55A-4f9lD:
18.81
1v55J-4f9lD:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4f9l 20.1 ANTI-BTN3A1
ANTIBODY FRAGMENT
(Mus
musculus) 		4 / 6 LEU D 142
ARG D 171
THR D 218
LEU D 217
 None
 0.97A 2dyrA-4f9lD:
undetectable
2dyrJ-4f9lD:
undetectable		 2dyrA-4f9lD:
18.81
2dyrJ-4f9lD:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4f9l 20.1 ANTI-BTN3A1
ANTIBODY FRAGMENT
(Mus
musculus) 		4 / 7 LEU D 142
ARG D 171
THR D 218
LEU D 217
 None
 0.95A 2dyrN-4f9lD:
undetectable
2dyrW-4f9lD:
undetectable		 2dyrN-4f9lD:
18.81
2dyrW-4f9lD:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_J_CHDJ101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4f9l 20.1 ANTI-BTN3A1
ANTIBODY FRAGMENT
(Mus
musculus) 		4 / 6 LEU D 142
ARG D 171
THR D 218
LEU D 217
 None
 0.92A 2dysA-4f9lD:
undetectable
2dysJ-4f9lD:
undetectable		 2dysA-4f9lD:
18.81
2dysJ-4f9lD:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_W_CHDW101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4f9l 20.1 ANTI-BTN3A1
ANTIBODY FRAGMENT
(Mus
musculus) 		4 / 6 LEU D 142
ARG D 171
THR D 218
LEU D 217
 None
 0.90A 2dysN-4f9lD:
undetectable
2dysW-4f9lD:
undetectable		 2dysN-4f9lD:
18.81
2dysW-4f9lD:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4f9l 20.1 ANTI-BTN3A1
ANTIBODY FRAGMENT
(Mus
musculus) 		4 / 6 LEU D 142
ARG D 171
THR D 218
LEU D 217
 None
 0.95A 2eijA-4f9lD:
undetectable
2eijJ-4f9lD:
undetectable		 2eijA-4f9lD:
18.81
2eijJ-4f9lD:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4f9l 20.1 ANTI-BTN3A1
ANTIBODY FRAGMENT
(Mus
musculus) 		4 / 8 LEU D 142
ARG D 171
THR D 218
LEU D 217
 None
 0.90A 2eijN-4f9lD:
undetectable
2eijW-4f9lD:
undetectable		 2eijN-4f9lD:
18.81
2eijW-4f9lD:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4f9l 20.1 ANTI-BTN3A1
ANTIBODY FRAGMENT
(Mus
musculus) 		4 / 7 LEU D 142
ARG D 171
THR D 218
LEU D 217
 None
 0.90A 2eikA-4f9lD:
undetectable
2eikJ-4f9lD:
undetectable		 2eikA-4f9lD:
18.81
2eikJ-4f9lD:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4f9l 20.1 ANTI-BTN3A1
ANTIBODY FRAGMENT
(Mus
musculus) 		4 / 8 LEU D 142
ARG D 171
THR D 218
LEU D 217
 None
 0.91A 2eikN-4f9lD:
undetectable
2eikW-4f9lD:
undetectable		 2eikN-4f9lD:
18.81
2eikW-4f9lD:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4f9l 20.1 ANTI-BTN3A1
ANTIBODY FRAGMENT
(Mus
musculus) 		4 / 6 LEU D 142
ARG D 171
THR D 218
LEU D 217
 None
 0.93A 2eilA-4f9lD:
undetectable
2eilJ-4f9lD:
undetectable		 2eilA-4f9lD:
18.81
2eilJ-4f9lD:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4f9l 20.1 ANTI-BTN3A1
ANTIBODY FRAGMENT
(Mus
musculus) 		4 / 8 LEU D 142
ARG D 171
THR D 218
LEU D 217
 None
 0.90A 2eilN-4f9lD:
undetectable
2eilW-4f9lD:
undetectable		 2eilN-4f9lD:
18.81
2eilW-4f9lD:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UVN_B_ECNB1406_1
(CYTOCHROME P450 130)		 4f9l 20.1 ANTI-BTN3A1
ANTIBODY FRAGMENT
(Mus
musculus) 		5 / 11 ASP D 234
PRO D 237
GLY D  91
LEU D  46
TYR D  49
 None
 1.38A 2uvnB-4f9lD:
undetectable		 2uvnB-4f9lD:
18.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4f9l 20.1 ANTI-BTN3A1
ANTIBODY FRAGMENT
(Mus
musculus) 		4 / 6 LEU D 142
ARG D 171
THR D 218
LEU D 217
 None
 0.94A 2zxwA-4f9lD:
undetectable
2zxwJ-4f9lD:
undetectable		 2zxwA-4f9lD:
18.81
2zxwJ-4f9lD:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4f9l 20.1 ANTI-BTN3A1
ANTIBODY FRAGMENT
(Mus
musculus) 		4 / 7 LEU D 142
ARG D 171
THR D 218
LEU D 217
 None
 1.00A 3ablA-4f9lD:
undetectable
3ablJ-4f9lD:
undetectable		 3ablA-4f9lD:
18.81
3ablJ-4f9lD:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4f9l 20.1 ANTI-BTN3A1
ANTIBODY FRAGMENT
(Mus
musculus) 		4 / 6 LEU D 142
ARG D 171
THR D 218
LEU D 217
 None
 1.00A 3abmA-4f9lD:
undetectable
3abmJ-4f9lD:
undetectable		 3abmA-4f9lD:
18.81
3abmJ-4f9lD:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4f9l 20.1 ANTI-BTN3A1
ANTIBODY FRAGMENT
(Mus
musculus) 		4 / 7 LEU D 142
ARG D 171
THR D 218
LEU D 217
 None
 0.96A 3ag3A-4f9lD:
undetectable
3ag3J-4f9lD:
undetectable		 3ag3A-4f9lD:
18.81
3ag3J-4f9lD:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 4f9l 20.1 ANTI-BTN3A1
ANTIBODY FRAGMENT
(Mus
musculus) 		4 / 6 LEU D 142
ARG D 171
THR D 218
LEU D 217
 None
 0.91A 3asnA-4f9lD:
undetectable
3asnJ-4f9lD:
undetectable		 3asnA-4f9lD:
18.81
3asnJ-4f9lD:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 4f9l 20.1 ANTI-BTN3A1
ANTIBODY FRAGMENT
(Mus
musculus) 		4 / 8 LEU D 142
ARG D 171
THR D 218
LEU D 217
 None
 0.88A 3asnN-4f9lD:
undetectable
3asnW-4f9lD:
undetectable		 3asnN-4f9lD:
18.81
3asnW-4f9lD:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 4f9l 20.1 ANTI-BTN3A1
ANTIBODY FRAGMENT
(Mus
musculus) 		4 / 6 LEU D 142
ARG D 171
THR D 218
LEU D 217
 None
 0.93A 3asoA-4f9lD:
undetectable
3asoJ-4f9lD:
undetectable		 3asoA-4f9lD:
18.81
3asoJ-4f9lD:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ROD_A_NCAA302_0
(NICOTINAMIDE
N-METHYLTRANSFERASE)		 4f9l 20.1 ANTI-BTN3A1
ANTIBODY FRAGMENT
(Mus
musculus) 		4 / 8 ASP D 231
ALA D 239
SER D  34
TYR D  96
 None
 0.97A 3rodA-4f9lD:
undetectable		 3rodA-4f9lD:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_J_ZPCJ1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4f9l 20.1 ANTI-BTN3A1
ANTIBODY FRAGMENT
(Mus
musculus) 		4 / 5 GLU D 230
GLU D 181
TYR D  94
HIS D  92
 None
 1.49A 4a97J-4f9lD:
undetectable		 4a97J-4f9lD:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4f9l 20.1 ANTI-BTN3A1
ANTIBODY FRAGMENT
(Mus
musculus) 		4 / 7 LEU D 142
ARG D 171
THR D 218
LEU D 217
 None
 0.95A 5b1bA-4f9lD:
undetectable
5b1bJ-4f9lD:
undetectable		 5b1bA-4f9lD:
18.81
5b1bJ-4f9lD:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4f9l 20.1 ANTI-BTN3A1
ANTIBODY FRAGMENT
(Mus
musculus) 		4 / 7 LEU D 142
ARG D 171
THR D 218
LEU D 217
 None
 0.93A 5iy5A-4f9lD:
undetectable
5iy5J-4f9lD:
undetectable		 5iy5A-4f9lD:
18.81
5iy5J-4f9lD:
11.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4f9l 20.1 ANTI-BTN3A1
ANTIBODY FRAGMENT
(Mus
musculus) 		3 / 3 TYR D 158
ARG D 208
THR D 161
 None
 0.80A 5z84J-4f9lD:
undetectable		 5z84J-4f9lD:
11.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4f9l 20.1 ANTI-BTN3A1
ANTIBODY FRAGMENT
(Mus
musculus) 		4 / 8 LEU D 142
ARG D 171
THR D 218
LEU D 217
 None
 0.94A 5zcqN-4f9lD:
undetectable
5zcqW-4f9lD:
undetectable		 5zcqN-4f9lD:
18.81
5zcqW-4f9lD:
11.67