SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fa0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4fa0 GROUP XVI
PHOSPHOLIPASE A1/A2
(Homo
sapiens) 		4 / 5 PRO A   8
PRO A  10
ILE A  93
GLY A  11
 None
 1.13A 2jkjD-4fa0A:
undetectable		 2jkjD-4fa0A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKJ_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 4fa0 GROUP XVI
PHOSPHOLIPASE A1/A2
(Homo
sapiens) 		4 / 5 PRO A   8
PRO A  10
ILE A  93
GLY A  11
 None
 1.12A 2jkjF-4fa0A:
undetectable		 2jkjF-4fa0A:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FRQ_B_ERYB195_1
(REPRESSOR PROTEIN
MPHR(A))		 4fa0 GROUP XVI
PHOSPHOLIPASE A1/A2
(Homo
sapiens) 		4 / 7 ASN A  77
ARG A  22
HIS A  23
ALA A  25
 None
 1.38A 3frqB-4fa0A:
undetectable		 3frqB-4fa0A:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_X_BEZX801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 4fa0 GROUP XVI
PHOSPHOLIPASE A1/A2
(Homo
sapiens) 		4 / 5 ARG A 121
ILE A  26
GLY A  29
ILE A  92
 None
 0.89A 5dzki-4fa0A:
undetectable
5dzkj-4fa0A:
undetectable
5dzkx-4fa0A:
undetectable		 5dzki-4fa0A:
22.45
5dzkj-4fa0A:
22.45
5dzkx-4fa0A:
2.94