SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4faj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 4faj PRGZ
(Enterococcus
faecalis) 		5 / 12 VAL A 443
LEU A 415
ALA A 345
ILE A 346
ILE A 530
 None
 0.99A 1epbB-4fajA:
undetectable		 1epbB-4fajA:
16.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1864_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 4faj PRGZ
(Enterococcus
faecalis) 		3 / 3 TRP A 469
HIS A 491
MET A 489
 None
 1.04A 1l5qB-4fajA:
undetectable		 1l5qB-4fajA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_1
(LIVER
CARBOXYLESTERASE I)		 4faj PRGZ
(Enterococcus
faecalis) 		5 / 12 LEU A 415
GLY A 427
LEU A 355
ILE A 346
LEU A 434
 None
 0.94A 1mx1D-4fajA:
undetectable		 1mx1D-4fajA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 4faj PRGZ
(Enterococcus
faecalis) 		4 / 8 GLY A 427
GLN A 431
VAL A 417
PRO A 447
 None
 0.96A 1rxcB-4fajA:
undetectable		 1rxcB-4fajA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_C_URFC2081_1
(URIDINE
PHOSPHORYLASE)		 4faj PRGZ
(Enterococcus
faecalis) 		4 / 7 GLY A 427
GLN A 431
VAL A 417
PRO A 447
 None
 1.03A 1rxcC-4fajA:
undetectable		 1rxcC-4fajA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_D_URFD2021_1
(URIDINE
PHOSPHORYLASE)		 4faj PRGZ
(Enterococcus
faecalis) 		4 / 7 GLY A 427
GLN A 431
VAL A 417
PRO A 447
 None
 0.94A 1rxcD-4fajA:
undetectable		 1rxcD-4fajA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_E_URFE2031_1
(URIDINE
PHOSPHORYLASE)		 4faj PRGZ
(Enterococcus
faecalis) 		4 / 8 GLY A 427
GLN A 431
VAL A 417
PRO A 447
 None
 0.97A 1rxcE-4fajA:
undetectable		 1rxcE-4fajA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)		 4faj PRGZ
(Enterococcus
faecalis) 		4 / 7 GLY A 427
GLN A 431
VAL A 417
PRO A 447
 None
 0.94A 1rxcF-4fajA:
undetectable		 1rxcF-4fajA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_I_URFI2041_1
(URIDINE
PHOSPHORYLASE)		 4faj PRGZ
(Enterococcus
faecalis) 		4 / 8 GLY A 427
GLN A 431
VAL A 417
PRO A 447
 None
 0.97A 1rxcI-4fajA:
undetectable		 1rxcI-4fajA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_K_URFK2061_1
(URIDINE
PHOSPHORYLASE)		 4faj PRGZ
(Enterococcus
faecalis) 		4 / 8 GLY A 427
GLN A 431
VAL A 417
PRO A 447
 None
 0.94A 1rxcK-4fajA:
undetectable		 1rxcK-4fajA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)		 4faj PRGZ
(Enterococcus
faecalis) 		4 / 7 GLY A 427
GLN A 431
VAL A 417
PRO A 447
 None
 0.94A 1rxcL-4fajA:
undetectable		 1rxcL-4fajA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S1X_A_NVPA999_1
(REVERSE
TRANSCRIPTASE)		 4faj PRGZ
(Enterococcus
faecalis) 		4 / 8 LEU A 241
GLY A 227
TRP A 253
LEU A  86
 None
 0.95A 1s1xA-4fajA:
undetectable		 1s1xA-4fajA:
23.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_B_TFPB203_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 4faj PRGZ
(Enterococcus
faecalis) 		4 / 6 PHE A 321
VAL A 527
LEU A 521
SER A 487
 None
 0.99A 1wrlB-4fajA:
undetectable		 1wrlB-4fajA:
12.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_2
(CES1 PROTEIN)		 4faj PRGZ
(Enterococcus
faecalis) 		4 / 4 LEU A 191
PRO A  75
ILE A 107
LEU A  94
 None
 1.02A 1ya4B-4fajA:
undetectable		 1ya4B-4fajA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_C_CTXC3_2
(CES1 PROTEIN)		 4faj PRGZ
(Enterococcus
faecalis) 		4 / 4 LEU A 191
PRO A  75
ILE A 107
LEU A  94
 None
 1.08A 1ya4C-4fajA:
undetectable		 1ya4C-4fajA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_2
(ADENOSINE KINASE)		 4faj PRGZ
(Enterococcus
faecalis) 		4 / 4 ALA A  66
VAL A  70
PHE A 274
THR A  85
 None
 1.34A 2pkkA-4fajA:
undetectable		 2pkkA-4fajA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBM_A_CAMA517_0
(CYTOCHROME P450-CAM)		 4faj PRGZ
(Enterococcus
faecalis) 		4 / 8 THR A 463
VAL A 443
VAL A 338
ILE A 342
 None
 0.83A 2qbmA-4fajA:
undetectable		 2qbmA-4fajA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBZ_A_VDXA501_1
(CYTOCHROME P450-SU1)		 4faj PRGZ
(Enterococcus
faecalis) 		6 / 11 VAL A  70
SER A 250
LEU A 241
VAL A  90
ILE A 255
ALA A 553
 None
None
None
None
None
GOL  A 602 (-3.7A)
 1.28A 2zbzA-4fajA:
undetectable		 2zbzA-4fajA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_A_URFA1301_1
(URIDINE
PHOSPHORYLASE)		 4faj PRGZ
(Enterococcus
faecalis) 		4 / 8 GLY A 427
GLN A 431
VAL A 417
PRO A 447
 None
 0.97A 4e1vA-4fajA:
undetectable		 4e1vA-4fajA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_B_URFB1301_1
(URIDINE
PHOSPHORYLASE)		 4faj PRGZ
(Enterococcus
faecalis) 		4 / 7 GLY A 427
GLN A 431
VAL A 417
PRO A 447
 None
 0.98A 4e1vB-4fajA:
undetectable		 4e1vB-4fajA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_C_URFC1301_1
(URIDINE
PHOSPHORYLASE)		 4faj PRGZ
(Enterococcus
faecalis) 		4 / 8 GLY A 427
GLN A 431
VAL A 417
PRO A 447
 None
 0.93A 4e1vC-4fajA:
undetectable		 4e1vC-4fajA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_D_URFD1301_1
(URIDINE
PHOSPHORYLASE)		 4faj PRGZ
(Enterococcus
faecalis) 		4 / 8 GLY A 427
GLN A 431
VAL A 417
PRO A 447
 None
 0.96A 4e1vD-4fajA:
undetectable		 4e1vD-4fajA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)		 4faj PRGZ
(Enterococcus
faecalis) 		4 / 8 GLY A 427
GLN A 431
VAL A 417
PRO A 447
 None
 0.96A 4e1vE-4fajA:
undetectable		 4e1vE-4fajA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_G_URFG1301_1
(URIDINE
PHOSPHORYLASE)		 4faj PRGZ
(Enterococcus
faecalis) 		4 / 8 GLY A 427
GLN A 431
VAL A 417
PRO A 447
 None
 0.95A 4e1vG-4fajA:
undetectable		 4e1vG-4fajA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_H_URFH1301_1
(URIDINE
PHOSPHORYLASE)		 4faj PRGZ
(Enterococcus
faecalis) 		4 / 8 GLY A 427
GLN A 431
VAL A 417
PRO A 447
 None
 0.94A 4e1vH-4fajA:
undetectable		 4e1vH-4fajA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_A_ACTA502_0
(RNA-DEPENDENT RNA
POLYMERASE)		 4faj PRGZ
(Enterococcus
faecalis) 		4 / 5 LYS A 515
LEU A 514
GLU A 518
LEU A 480
 None
 1.24A 4k4yA-4fajA:
undetectable		 4k4yA-4fajA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_E_ACTE503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 4faj PRGZ
(Enterococcus
faecalis) 		4 / 4 LYS A 515
LEU A 514
GLU A 518
LEU A 480
 None
 1.24A 4k4yE-4fajA:
undetectable		 4k4yE-4fajA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_I_ACTI503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 4faj PRGZ
(Enterococcus
faecalis) 		4 / 5 LYS A 515
LEU A 514
GLU A 518
LEU A 480
 None
 1.27A 4k4yI-4fajA:
undetectable		 4k4yI-4fajA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4C_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 4faj PRGZ
(Enterococcus
faecalis) 		4 / 8 THR A 463
VAL A 443
VAL A 338
ILE A 342
 None
 0.92A 4l4cB-4fajA:
undetectable		 4l4cB-4fajA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_A_MRVA1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 4faj PRGZ
(Enterococcus
faecalis) 		4 / 7 TYR A 311
GLN A  81
THR A  82
THR A  68
 None
 0.84A 4mbsA-4fajA:
undetectable		 4mbsA-4fajA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA301_0
(THAUMATIN-1)		 4faj PRGZ
(Enterococcus
faecalis) 		3 / 3 THR A 485
ASN A 486
SER A 487
 None
 0.76A 4tvtA-4fajA:
undetectable		 4tvtA-4fajA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HHJ_A_GLYA403_0
(RETRON-TYPE REVERSE
TRANSCRIPTASE)		 4faj PRGZ
(Enterococcus
faecalis) 		4 / 4 LEU A 355
LEU A 430
GLY A 427
GLU A 428
 None
 0.88A 5hhjA-4fajA:
undetectable		 5hhjA-4fajA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGJ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4faj PRGZ
(Enterococcus
faecalis) 		3 / 3 VAL A  70
VAL A 247
GLN A 230
 None
 0.59A 5qgjA-4fajA:
undetectable		 5qgjA-4fajA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGM_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4faj PRGZ
(Enterococcus
faecalis) 		3 / 3 VAL A  70
VAL A 247
GLN A 230
 None
 0.67A 5qgmA-4fajA:
undetectable		 5qgmA-4fajA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGN_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4faj PRGZ
(Enterococcus
faecalis) 		3 / 3 VAL A  70
VAL A 247
GLN A 230
 None
 0.58A 5qgnA-4fajA:
undetectable		 5qgnA-4fajA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGY_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4faj PRGZ
(Enterococcus
faecalis) 		3 / 3 VAL A  70
VAL A 247
GLN A 230
 None
 0.57A 5qgyA-4fajA:
undetectable		 5qgyA-4fajA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGZ_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4faj PRGZ
(Enterococcus
faecalis) 		3 / 3 VAL A  70
VAL A 247
GLN A 230
 None
 0.57A 5qgzA-4fajA:
undetectable		 5qgzA-4fajA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH0_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4faj PRGZ
(Enterococcus
faecalis) 		3 / 3 VAL A  70
VAL A 247
GLN A 230
 None
 0.57A 5qh0A-4fajA:
undetectable		 5qh0A-4fajA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH2_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4faj PRGZ
(Enterococcus
faecalis) 		3 / 3 VAL A  70
VAL A 247
GLN A 230
 None
 0.57A 5qh2A-4fajA:
undetectable		 5qh2A-4fajA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH3_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4faj PRGZ
(Enterococcus
faecalis) 		3 / 3 VAL A  70
VAL A 247
GLN A 230
 None
 0.58A 5qh3A-4fajA:
undetectable		 5qh3A-4fajA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH5_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4faj PRGZ
(Enterococcus
faecalis) 		3 / 3 VAL A  70
VAL A 247
GLN A 230
 None
 0.61A 5qh5A-4fajA:
undetectable		 5qh5A-4fajA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH6_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4faj PRGZ
(Enterococcus
faecalis) 		3 / 3 VAL A  70
VAL A 247
GLN A 230
 None
 0.60A 5qh6A-4fajA:
undetectable		 5qh6A-4fajA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH7_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4faj PRGZ
(Enterococcus
faecalis) 		3 / 3 VAL A  70
VAL A 247
GLN A 230
 None
 0.58A 5qh7A-4fajA:
undetectable		 5qh7A-4fajA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHA_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4faj PRGZ
(Enterococcus
faecalis) 		3 / 3 VAL A  70
VAL A 247
GLN A 230
 None
 0.57A 5qhaA-4fajA:
undetectable		 5qhaA-4fajA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHH_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 4faj PRGZ
(Enterococcus
faecalis) 		3 / 3 VAL A  70
VAL A 247
GLN A 230
 None
 0.58A 5qhhA-4fajA:
undetectable		 5qhhA-4fajA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V02_R_657R201_0
(CALMODULIN-1
SMALL CONDUCTANCE
CALCIUM-ACTIVATED
POTASSIUM CHANNEL
PROTEIN 2)		 4faj PRGZ
(Enterococcus
faecalis) 		5 / 10 ALA A 426
LEU A 430
LEU A 322
GLU A 423
VAL A 417
 None
 1.14A 5v02B-4fajA:
undetectable
5v02R-4fajA:
undetectable		 5v02B-4fajA:
11.17
5v02R-4fajA:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FTP_B_DM2B501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 4faj PRGZ
(Enterococcus
faecalis) 		5 / 9 LEU A 441
SER A 412
LEU A 407
VAL A 338
ASN A 335
 None
 1.28A 6ftpA-4fajA:
undetectable
6ftpB-4fajA:
undetectable		 6ftpA-4fajA:
9.72
6ftpB-4fajA:
7.83