SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fao'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YKI_A_NFZA1219_1 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	4fao	ACTIVIN RECEPTOR TYPE-2B (Homo sapiens)	4 / 8	TYR E 42 PHE E 95 ASN E 92 GLY E 58	None	1.01A	1ykiA-4faoE: undetectable 1ykiB-4faoE: undetectable	1ykiA-4faoE: 18.36 1ykiB-4faoE: 18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YKI_B_NFZB2219_1 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	4fao	ACTIVIN RECEPTOR TYPE-2B (Homo sapiens)	4 / 8	TYR E 42 PHE E 95 ASN E 92 GLY E 58	None	1.02A	1ykiA-4faoE: undetectable 1ykiB-4faoE: undetectable	1ykiA-4faoE: 18.36 1ykiB-4faoE: 18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YKI_C_NFZC3219_1 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	4fao	ACTIVIN RECEPTOR TYPE-2B (Homo sapiens)	4 / 8	TYR E 42 PHE E 95 ASN E 92 GLY E 58	None	1.00A	1ykiC-4faoE: undetectable 1ykiD-4faoE: undetectable	1ykiC-4faoE: 18.36 1ykiD-4faoE: 18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YKI_D_NFZD4219_1 (OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE)	4fao	ACTIVIN RECEPTOR TYPE-2B (Homo sapiens)	4 / 8	TYR E 42 PHE E 95 ASN E 92 GLY E 58	None	1.01A	1ykiC-4faoE: undetectable 1ykiD-4faoE: undetectable	1ykiC-4faoE: 18.36 1ykiD-4faoE: 18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HHJ_A_GLYA403_0 (RETRON-TYPE REVERSE TRANSCRIPTASE)	4fao	ACTIVIN RECEPTOR TYPE-2B (Homo sapiens)	4 / 4	LEU E 61 LEU E 39 GLY E 33 GLU E 34	None	1.22A	5hhjA-4faoE: undetectable	5hhjA-4faoE: 15.26

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1YKI_A_NFZA1219_1","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE;OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","4fao","ACTIVIN RECEPTOR TYPE-2B","Homo sapiens",4,"TYR E  42;PHE E  95;ASN E  92;GLY E  58","None","1.01A","1ykiA-4faoE:undetectable;1ykiB-4faoE:undetectable","1ykiA-4faoE:18.36;1ykiB-4faoE:18.36"],["1YKI_B_NFZB2219_1","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE;OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","4fao","ACTIVIN RECEPTOR TYPE-2B","Homo sapiens",4,"TYR E  42;PHE E  95;ASN E  92;GLY E  58","None","1.02A","1ykiA-4faoE:undetectable;1ykiB-4faoE:undetectable","1ykiA-4faoE:18.36;1ykiB-4faoE:18.36"],["1YKI_C_NFZC3219_1","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE;OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","4fao","ACTIVIN RECEPTOR TYPE-2B","Homo sapiens",4,"TYR E  42;PHE E  95;ASN E  92;GLY E  58","None","1.00A","1ykiC-4faoE:undetectable;1ykiD-4faoE:undetectable","1ykiC-4faoE:18.36;1ykiD-4faoE:18.36"],["1YKI_D_NFZD4219_1","OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE;OXYGEN-INSENSITIVE NAD(P)H NITROREDUCTASE","4fao","ACTIVIN RECEPTOR TYPE-2B","Homo sapiens",4,"TYR E  42;PHE E  95;ASN E  92;GLY E  58","None","1.01A","1ykiC-4faoE:undetectable;1ykiD-4faoE:undetectable","1ykiC-4faoE:18.36;1ykiD-4faoE:18.36"],["5HHJ_A_GLYA403_0","RETRON-TYPE REVERSE TRANSCRIPTASE","4fao","ACTIVIN RECEPTOR TYPE-2B","Homo sapiens",4,"LEU E  61;LEU E  39;GLY E  33;GLU E  34","None","1.22A","5hhjA-4faoE:undetectable","5hhjA-4faoE:15.26"]]