SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fb3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IE4_A_T44A128_1
(TRANSTHYRETIN)		 4fb3 LARGE T ANTIGEN
(Mus
musculus
polyomavirus
1) 		5 / 10 LYS A 362
LEU A 314
LYS A 321
LEU A 325
LEU A 348
 None
 1.32A 1ie4A-4fb3A:
undetectable
1ie4C-4fb3A:
undetectable		 1ie4A-4fb3A:
21.38
1ie4C-4fb3A:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QCA_A_FUAA221_1
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4fb3 LARGE T ANTIGEN
(Mus
musculus
polyomavirus
1) 		4 / 7 CYH A 338
PHE A 394
PHE A 349
LEU A 300
 None
 1.02A 1qcaA-4fb3A:
undetectable		 1qcaA-4fb3A:
19.72