SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fb5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_2
(PROTEIN (ADENOSINE
KINASE))		 4fb5 PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		3 / 3 LEU A 239
SER A 244
ASN A 154
 None
 0.84A 1bx4A-4fb5A:
undetectable		 1bx4A-4fb5A:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HWI_B_115B1_1
(HMG-COA REDUCTASE)		 4fb5 PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		5 / 9 GLU A 327
CYH A 328
ASN A 131
ALA A  19
LEU A   8
 None
 1.38A 1hwiA-4fb5A:
undetectable		 1hwiA-4fb5A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PKV_B_RBFB101_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 4fb5 PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		5 / 11 ILE A 368
VAL A 206
LEU A 185
THR A 208
ILE A 207
 None
 1.20A 1pkvA-4fb5A:
undetectable
1pkvB-4fb5A:
undetectable		 1pkvA-4fb5A:
13.91
1pkvB-4fb5A:
13.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PO7_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4fb5 PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		3 / 3 LEU A 193
PRO A 192
LEU A 196
 None
 0.57A 2po7B-4fb5A:
5.1		 2po7B-4fb5A:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fb5 PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		4 / 7 ILE A 271
LEU A 283
PHE A 281
ARG A 139
 None
 1.13A 2zxwN-4fb5A:
undetectable
2zxwW-4fb5A:
undetectable		 2zxwN-4fb5A:
20.61
2zxwW-4fb5A:
11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SAN_A_ZMRA901_2
(NEURAMINIDASE)		 4fb5 PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		4 / 5 ASP A  31
ARG A 329
ARG A 309
ILE A 332
 None
 1.41A 3sanA-4fb5A:
undetectable		 3sanA-4fb5A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SAN_B_ZMRB901_2
(NEURAMINIDASE)		 4fb5 PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		4 / 5 ASP A  31
ARG A 329
ARG A 309
ILE A 332
 None
 1.40A 3sanB-4fb5A:
undetectable		 3sanB-4fb5A:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYE_B_YTZB902_1
(DIHYDROPTEROATE
SYNTHASE)		 4fb5 PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		3 / 3 PHE A 164
LYS A 175
SER A 176
 None
 0.80A 3tyeB-4fb5A:
undetectable		 3tyeB-4fb5A:
25.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD393_1
(TETX2 PROTEIN)		 4fb5 PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		4 / 5 ILE A 351
ILE A 133
TYR A 130
GLU A 327
 None
 1.17A 4a99D-4fb5A:
3.5		 4a99D-4fb5A:
24.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD4_C_AOQC4003_1
(CYTOCHROME B)		 4fb5 PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		5 / 12 GLY A   5
VAL A  75
ILE A   6
LEU A 331
ILE A 325
 None
 1.08A 4pd4C-4fb5A:
undetectable		 4pd4C-4fb5A:
23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YSH_B_GLYB401_0
(GLYCINE OXIDASE)		 4fb5 PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		4 / 6 PHE A 295
GLY A 269
TYR A 284
ALA A 286
 None
 1.23A 4yshB-4fb5A:
undetectable		 4yshB-4fb5A:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IH0_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 4fb5 PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		4 / 6 TYR A 182
HIS A 356
ILE A 370
TYR A 130
 None
 1.09A 5ih0A-4fb5A:
undetectable		 5ih0A-4fb5A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XU8_A_DX4A701_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 2)		 4fb5 PROBABLE
OXIDOREDUCTASE
PROTEIN
(Rhizobium
etli) 		4 / 8 GLY A 348
LEU A 349
ALA A 119
PHE A 345
 None
 0.91A 5xu8A-4fb5A:
undetectable		 5xu8A-4fb5A:
22.50