SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fbd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_C_CHDC3271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE III
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4fbd PUTATIVE
UNCHARACTERIZED
PROTEIN
(Toxoplasma
gondii) 		4 / 7 LYS A 171
LEU A 134
GLN A 173
PHE A 133
 None
 1.11A 1v55C-4fbdA:
undetectable
1v55J-4fbdA:
undetectable		 1v55C-4fbdA:
21.55
1v55J-4fbdA:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP310_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4fbd PUTATIVE
UNCHARACTERIZED
PROTEIN
(Toxoplasma
gondii) 		4 / 7 LYS A 171
LEU A 134
GLN A 173
PHE A 133
 None
 1.05A 2dysP-4fbdA:
undetectable
2dysW-4fbdA:
undetectable		 2dysP-4fbdA:
21.55
2dysW-4fbdA:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4fbd PUTATIVE
UNCHARACTERIZED
PROTEIN
(Toxoplasma
gondii) 		4 / 7 LYS A 171
LEU A 134
GLN A 173
PHE A 133
 None
 1.06A 2einC-4fbdA:
undetectable
2einJ-4fbdA:
undetectable		 2einC-4fbdA:
21.55
2einJ-4fbdA:
13.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BRF_A_SORA2_0
(LIN-12 AND GLP-1
PHENOTYPE PROTEIN 1,
ISOFORM A)		 4fbd PUTATIVE
UNCHARACTERIZED
PROTEIN
(Toxoplasma
gondii) 		3 / 3 LYS A 214
LYS A 207
VAL A 210
 None
 1.01A 3brfA-4fbdA:
undetectable		 3brfA-4fbdA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9K_A_TYLA2200_1
(CREB-BINDING PROTEIN)		 4fbd PUTATIVE
UNCHARACTERIZED
PROTEIN
(Toxoplasma
gondii) 		4 / 6 VAL A  54
LEU A 136
ILE A 167
VAL A  83
 None
 0.94A 4a9kA-4fbdA:
undetectable		 4a9kA-4fbdA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_D_FOLD301_1
(FOLATE RECEPTOR
ALPHA)		 4fbd PUTATIVE
UNCHARACTERIZED
PROTEIN
(Toxoplasma
gondii) 		3 / 3 HIS A  76
TRP A 165
SER A 178
 None
 1.07A 4lrhD-4fbdA:
undetectable		 4lrhD-4fbdA:
19.54