SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fbo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_A_NOVA400_2
(DNA GYRASE SUBUNIT B)		 4fbo PSEUDOMONAS
FLUORESCENS
AGGLUTININ
(Pseudomonas
fluorescens) 		3 / 3 ASN A  69
PHE A  47
VAL A 100
 None
 0.85A 1kijA-4fboA:
undetectable		 1kijA-4fboA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_D_THAD4_2
(LIVER
CARBOXYLESTERASE I)		 4fbo PSEUDOMONAS
FLUORESCENS
AGGLUTININ
(Pseudomonas
fluorescens) 		3 / 3 PHE A 128
LEU A 103
MET A  51
 None
 0.86A 1mx1D-4fboA:
undetectable		 1mx1D-4fboA:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTF_A_2TNA201_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 4fbo PSEUDOMONAS
FLUORESCENS
AGGLUTININ
(Pseudomonas
fluorescens) 		4 / 5 LEU A 114
ILE A 132
SER A   2
GLY A  26
 None
 0.88A 2otfA-4fboA:
undetectable		 2otfA-4fboA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_2
(BETA-1 ADRENERGIC
RECEPTOR)		 4fbo PSEUDOMONAS
FLUORESCENS
AGGLUTININ
(Pseudomonas
fluorescens) 		3 / 3 VAL A 100
ASN A   8
TRP A  10
 None
 0.88A 2y00B-4fboA:
undetectable		 2y00B-4fboA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4fbo PSEUDOMONAS
FLUORESCENS
AGGLUTININ
(Pseudomonas
fluorescens) 		3 / 3 SER A  13
GLY A  12
GLN A   9
 None
 0.36A 3v4tH-4fboA:
undetectable		 3v4tH-4fboA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMB_A_SREA603_1
(TRANSPORTER)		 4fbo PSEUDOMONAS
FLUORESCENS
AGGLUTININ
(Pseudomonas
fluorescens) 		5 / 9 VAL A   6
ALA A   5
TYR A   4
GLY A 116
PHE A 128
 None
 1.34A 4mmbA-4fboA:
undetectable		 4mmbA-4fboA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_B_29QB603_1
(TRANSPORTER)		 4fbo PSEUDOMONAS
FLUORESCENS
AGGLUTININ
(Pseudomonas
fluorescens) 		5 / 9 VAL A   6
ALA A   5
TYR A   4
GLY A 116
PHE A 128
 None
 1.33A 4mmeB-4fboA:
undetectable		 4mmeB-4fboA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_A_29QA603_1
(TRANSPORTER)		 4fbo PSEUDOMONAS
FLUORESCENS
AGGLUTININ
(Pseudomonas
fluorescens) 		5 / 9 VAL A   6
ALA A   5
TYR A   4
GLY A 116
PHE A 128
 None
 1.39A 4mmfA-4fboA:
undetectable		 4mmfA-4fboA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_B_29QB603_1
(TRANSPORTER)		 4fbo PSEUDOMONAS
FLUORESCENS
AGGLUTININ
(Pseudomonas
fluorescens) 		5 / 9 VAL A   6
ALA A   5
TYR A   4
GLY A 116
PHE A 128
 None
 1.35A 4mmfB-4fboA:
undetectable		 4mmfB-4fboA:
15.74