SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fbv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4fbv MYXOBACTERIAL
HEMAGGLUTININ
(Myxococcus
xanthus) 		5 / 12 GLY A 197
THR A 198
ALA A 172
SER A 182
GLY A 222
 EDO  A 311 (-3.5A)
EDO  A 311 (-3.9A)
None
None
None
 1.27A 1nbiC-4fbvA:
undetectable		 1nbiC-4fbvA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4fbv MYXOBACTERIAL
HEMAGGLUTININ
(Myxococcus
xanthus) 		5 / 12 GLY A 197
THR A 198
ALA A 172
SER A 182
GLY A 222
 EDO  A 311 (-3.5A)
EDO  A 311 (-3.9A)
None
None
None
 1.28A 1nbiD-4fbvA:
undetectable		 1nbiD-4fbvA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFL_A_5CHA693_1
(LACTOTRANSFERRIN)		 4fbv MYXOBACTERIAL
HEMAGGLUTININ
(Myxococcus
xanthus) 		4 / 4 THR A 161
VAL A 170
GLY A 197
THR A 180
 None
None
EDO  A 311 (-3.5A)
None
 1.07A 3cflA-4fbvA:
undetectable		 3cflA-4fbvA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		 4fbv MYXOBACTERIAL
HEMAGGLUTININ
(Myxococcus
xanthus) 		4 / 8 ASP A  29
SER A 139
LEU A 159
ASP A 136
 None
 0.98A 3m0wE-4fbvA:
undetectable
3m0wF-4fbvA:
undetectable
3m0wG-4fbvA:
undetectable
3m0wH-4fbvA:
undetectable		 3m0wE-4fbvA:
13.16
3m0wF-4fbvA:
13.16
3m0wG-4fbvA:
13.16
3m0wH-4fbvA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4fbv MYXOBACTERIAL
HEMAGGLUTININ
(Myxococcus
xanthus) 		3 / 3 SER A  13
GLY A  12
GLN A   9
 None
 0.52A 3v4tH-4fbvA:
undetectable		 3v4tH-4fbvA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4fbv MYXOBACTERIAL
HEMAGGLUTININ
(Myxococcus
xanthus) 		3 / 3 SER A 147
GLY A 146
GLN A 143
 None
MAN  A 303 (-3.4A)
None
 0.48A 3v4tH-4fbvA:
undetectable		 3v4tH-4fbvA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACHG301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4fbv MYXOBACTERIAL
HEMAGGLUTININ
(Myxococcus
xanthus) 		4 / 8 TRP A 224
THR A 161
TYR A 138
LEU A  22
 None
 1.29A 3wipG-4fbvA:
undetectable
3wipH-4fbvA:
undetectable		 3wipG-4fbvA:
21.60
3wipH-4fbvA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_J_ACHJ301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4fbv MYXOBACTERIAL
HEMAGGLUTININ
(Myxococcus
xanthus) 		4 / 8 LEU A  22
TRP A 224
THR A 161
TYR A 138
 None
 1.26A 3wipF-4fbvA:
undetectable
3wipJ-4fbvA:
undetectable		 3wipF-4fbvA:
21.60
3wipJ-4fbvA:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WZE_A_BAXA1201_2
(VASCULAR ENDOTHELIAL
GROWTH FACTOR
RECEPTOR 2)		 4fbv MYXOBACTERIAL
HEMAGGLUTININ
(Myxococcus
xanthus) 		5 / 8 VAL A 235
VAL A 234
LEU A 237
ILE A 253
PHE A 262
 None
 0.98A 3wzeA-4fbvA:
undetectable		 3wzeA-4fbvA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JQ1_B_NPSB401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 4fbv MYXOBACTERIAL
HEMAGGLUTININ
(Myxococcus
xanthus) 		4 / 8 TYR A   4
VAL A 103
ILE A  38
TRP A  90
 None
 0.71A 4jq1B-4fbvA:
undetectable		 4jq1B-4fbvA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WRY_A_URFA302_1
(URACIL-DNA
GLYCOSYLASE)		 4fbv MYXOBACTERIAL
HEMAGGLUTININ
(Myxococcus
xanthus) 		4 / 8 GLY A 231
GLN A 232
SER A  67
ASN A 233
 EDO  A 313 (-4.7A)
None
None
EDO  A 313 (-3.9A)
 1.01A 4wryA-4fbvA:
undetectable		 4wryA-4fbvA:
21.55