SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fc3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZU_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4fc3 IRON-REGULATED
SURFACE DETERMINANT
PROTEIN H
(Staphylococcus
aureus) 		5 / 12 ILE E 104
ALA E   6
ILE E 117
PHE E  79
LEU E  10
 None
 1.05A 3dzuA-4fc3E:
undetectable		 3dzuA-4fc3E:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU9_A_478A401_1
(PROTEASE)		 4fc3 IRON-REGULATED
SURFACE DETERMINANT
PROTEIN H
(Staphylococcus
aureus) 		4 / 8 ALA E  55
ASP E  33
ILE E  65
VAL E 115
 None
 0.78A 3nu9A-4fc3E:
undetectable		 3nu9A-4fc3E:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_2
(SCRFP-TAG,GP41)		 4fc3 IRON-REGULATED
SURFACE DETERMINANT
PROTEIN H
(Staphylococcus
aureus) 		3 / 3 LYS E  77
TRP E  76
SER E   9
 None
 1.29A 5nwwA-4fc3E:
undetectable		 5nwwA-4fc3E:
10.98