SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fc7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.16A 1c9sA-4fc7A:
undetectable
1c9sK-4fc7A:
undetectable		 1c9sA-4fc7A:
16.60
1c9sK-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.15A 1c9sA-4fc7A:
undetectable
1c9sB-4fc7A:
undetectable		 1c9sA-4fc7A:
16.60
1c9sB-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.15A 1c9sB-4fc7A:
undetectable
1c9sC-4fc7A:
undetectable		 1c9sB-4fc7A:
16.60
1c9sC-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.18A 1c9sC-4fc7A:
undetectable
1c9sD-4fc7A:
undetectable		 1c9sC-4fc7A:
16.60
1c9sD-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.16A 1c9sD-4fc7A:
undetectable
1c9sE-4fc7A:
undetectable		 1c9sD-4fc7A:
16.60
1c9sE-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.17A 1c9sE-4fc7A:
undetectable
1c9sF-4fc7A:
undetectable		 1c9sE-4fc7A:
16.60
1c9sF-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.18A 1c9sF-4fc7A:
undetectable
1c9sG-4fc7A:
undetectable		 1c9sF-4fc7A:
16.60
1c9sG-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.18A 1c9sG-4fc7A:
undetectable
1c9sH-4fc7A:
undetectable		 1c9sG-4fc7A:
16.60
1c9sH-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.20A 1c9sH-4fc7A:
undetectable
1c9sI-4fc7A:
undetectable		 1c9sH-4fc7A:
16.60
1c9sI-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.18A 1c9sJ-4fc7A:
undetectable
1c9sK-4fc7A:
undetectable		 1c9sJ-4fc7A:
16.60
1c9sK-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.22A 1c9sL-4fc7A:
undetectable
1c9sM-4fc7A:
undetectable		 1c9sL-4fc7A:
16.60
1c9sM-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.21A 1c9sM-4fc7A:
undetectable
1c9sN-4fc7A:
undetectable		 1c9sM-4fc7A:
16.60
1c9sN-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.24A 1c9sO-4fc7A:
undetectable
1c9sP-4fc7A:
undetectable		 1c9sO-4fc7A:
16.60
1c9sP-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.18A 1c9sQ-4fc7A:
undetectable
1c9sR-4fc7A:
undetectable		 1c9sQ-4fc7A:
16.60
1c9sR-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.21A 1c9sS-4fc7A:
undetectable
1c9sT-4fc7A:
undetectable		 1c9sS-4fc7A:
16.60
1c9sT-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.19A 1c9sL-4fc7A:
undetectable
1c9sV-4fc7A:
undetectable		 1c9sL-4fc7A:
16.60
1c9sV-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.18A 1gtfA-4fc7A:
undetectable
1gtfK-4fc7A:
undetectable		 1gtfA-4fc7A:
16.60
1gtfK-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.16A 1gtfA-4fc7A:
undetectable
1gtfB-4fc7A:
undetectable		 1gtfA-4fc7A:
16.60
1gtfB-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.17A 1gtfB-4fc7A:
undetectable
1gtfC-4fc7A:
undetectable		 1gtfB-4fc7A:
16.60
1gtfC-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.17A 1gtfC-4fc7A:
undetectable
1gtfD-4fc7A:
undetectable		 1gtfC-4fc7A:
16.60
1gtfD-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.18A 1gtfE-4fc7A:
undetectable
1gtfF-4fc7A:
undetectable		 1gtfE-4fc7A:
16.60
1gtfF-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.18A 1gtfF-4fc7A:
undetectable
1gtfG-4fc7A:
undetectable		 1gtfF-4fc7A:
16.60
1gtfG-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.17A 1gtfG-4fc7A:
undetectable
1gtfH-4fc7A:
undetectable		 1gtfG-4fc7A:
16.60
1gtfH-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.20A 1gtfH-4fc7A:
undetectable
1gtfI-4fc7A:
undetectable		 1gtfH-4fc7A:
16.60
1gtfI-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.17A 1gtfI-4fc7A:
undetectable
1gtfJ-4fc7A:
undetectable		 1gtfI-4fc7A:
16.60
1gtfJ-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.23A 1gtfO-4fc7A:
undetectable
1gtfP-4fc7A:
undetectable		 1gtfO-4fc7A:
16.60
1gtfP-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.21A 1gtfP-4fc7A:
undetectable
1gtfQ-4fc7A:
undetectable		 1gtfP-4fc7A:
16.60
1gtfQ-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.20A 1gtfR-4fc7A:
undetectable
1gtfS-4fc7A:
undetectable		 1gtfR-4fc7A:
16.60
1gtfS-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.24A 1gtfT-4fc7A:
undetectable
1gtfU-4fc7A:
undetectable		 1gtfT-4fc7A:
16.60
1gtfU-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 11 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.23A 1gtfU-4fc7A:
undetectable
1gtfV-4fc7A:
undetectable		 1gtfU-4fc7A:
16.60
1gtfV-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.22A 1gtfL-4fc7A:
undetectable
1gtfV-4fc7A:
undetectable		 1gtfL-4fc7A:
16.60
1gtfV-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.24A 1gtnN-4fc7A:
undetectable
1gtnO-4fc7A:
undetectable		 1gtnN-4fc7A:
16.60
1gtnO-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.21A 1gtnR-4fc7A:
undetectable
1gtnS-4fc7A:
undetectable		 1gtnR-4fc7A:
16.60
1gtnS-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.20A 1gtnU-4fc7A:
undetectable
1gtnV-4fc7A:
undetectable		 1gtnU-4fc7A:
16.60
1gtnV-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J3J_B_CP6B709_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 ALA A  58
ASN A 112
SER A 145
ILE A 160
ILE A 111
 None
 1.50A 1j3jB-4fc7A:
undetectable		 1j3jB-4fc7A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SGU_B_MK1B2632_2
(POL POLYPROTEIN)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 12 ASP A 137
GLY A 116
ALA A 115
ILE A 163
ILE A  40
 None
COA  A 402 (-3.5A)
NAP  A 401 (-3.2A)
NAP  A 401 (-4.6A)
NAP  A 401 (-4.0A)
 0.88A 1sguB-4fc7A:
undetectable		 1sguB-4fc7A:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_A_TRPA81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.18A 1utdA-4fc7A:
undetectable
1utdB-4fc7A:
undetectable		 1utdA-4fc7A:
16.60
1utdB-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_C_TRPC81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.19A 1utdC-4fc7A:
undetectable
1utdD-4fc7A:
undetectable		 1utdC-4fc7A:
16.60
1utdD-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_D_TRPD81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.18A 1utdD-4fc7A:
undetectable
1utdE-4fc7A:
undetectable		 1utdD-4fc7A:
16.60
1utdE-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_G_TRPG81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.19A 1utdG-4fc7A:
undetectable
1utdH-4fc7A:
undetectable		 1utdG-4fc7A:
16.60
1utdH-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.17A 1utdH-4fc7A:
undetectable
1utdI-4fc7A:
undetectable		 1utdH-4fc7A:
16.60
1utdI-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_K_TRPK81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  68
HIS A  54
THR A  55
ILE A  57
 None
 1.39A 1utdA-4fc7A:
undetectable
1utdK-4fc7A:
undetectable		 1utdA-4fc7A:
16.60
1utdK-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_K_TRPK81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.19A 1utdA-4fc7A:
undetectable
1utdK-4fc7A:
undetectable		 1utdA-4fc7A:
16.60
1utdK-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_M_TRPM81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 11 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.21A 1utdM-4fc7A:
undetectable
1utdN-4fc7A:
undetectable		 1utdM-4fc7A:
16.60
1utdN-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_N_TRPN81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.20A 1utdN-4fc7A:
undetectable
1utdO-4fc7A:
undetectable		 1utdN-4fc7A:
16.60
1utdO-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_Q_TRPQ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.20A 1utdQ-4fc7A:
undetectable
1utdR-4fc7A:
undetectable		 1utdQ-4fc7A:
16.60
1utdR-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.21A 1utdR-4fc7A:
undetectable
1utdS-4fc7A:
undetectable		 1utdR-4fc7A:
16.60
1utdS-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_B_SAMB4001_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 12 GLY A  35
GLY A  37
ASP A  86
VAL A  87
ILE A 136
 NAP  A 401 (-3.5A)
NAP  A 401 ( 4.9A)
NAP  A 401 (-3.2A)
NAP  A 401 (-3.6A)
NAP  A 401 (-3.8A)
 0.87A 1zq9B-4fc7A:
6.1		 1zq9B-4fc7A:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMM_B_SAMB301_0
(UPF0217 PROTEIN
AF_1056)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 11 ILE A  40
GLY A  41
GLY A  36
LEU A 206
SER A 205
 NAP  A 401 (-4.0A)
None
None
None
None
 0.85A 2qmmA-4fc7A:
2.4
2qmmB-4fc7A:
undetectable		 2qmmA-4fc7A:
21.71
2qmmB-4fc7A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_A_QPSA1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 12 PHE A  32
SER A 145
THR A 141
GLY A  35
ALA A  58
 None
None
None
NAP  A 401 (-3.5A)
None
 1.13A 2x2iA-4fc7A:
undetectable		 2x2iA-4fc7A:
14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 11 THR A 214
ILE A  40
GLY A  39
GLY A 216
PRO A 208
 NAP  A 401 (-3.0A)
NAP  A 401 (-4.0A)
NAP  A 401 (-3.2A)
NAP  A 401 (-3.2A)
NAP  A 401 (-4.0A)
 1.24A 2y7kA-4fc7A:
undetectable		 2y7kA-4fc7A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_C_SALC1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 12 THR A 214
ILE A  40
GLY A  39
GLY A 216
PRO A 208
 NAP  A 401 (-3.0A)
NAP  A 401 (-4.0A)
NAP  A 401 (-3.2A)
NAP  A 401 (-3.2A)
NAP  A 401 (-4.0A)
 1.34A 2y7kC-4fc7A:
undetectable		 2y7kC-4fc7A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7P_A_SALA1000_1
(LYSR-TYPE REGULATORY
PROTEIN)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A 214
ILE A  40
GLY A  39
GLY A 216
PRO A 208
 NAP  A 401 (-3.0A)
NAP  A 401 (-4.0A)
NAP  A 401 (-3.2A)
NAP  A 401 (-3.2A)
NAP  A 401 (-4.0A)
 1.22A 2y7pA-4fc7A:
undetectable		 2y7pA-4fc7A:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BOG_C_DVAC10_0
(6.5 KDA GLYCINE-RICH
ANTIFREEZE PROTEIN)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		3 / 3 GLY A 179
GLY A 171
GLY A 168
 None
 0.39A 3bogC-4fc7A:
undetectable		 3bogC-4fc7A:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_B_THHB401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		4 / 8 SER A 145
LEU A 192
THR A 164
GLY A 262
 None
 0.86A 3dcjB-4fc7A:
5.2		 3dcjB-4fc7A:
26.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DLC_A_SAMA220_0
(PUTATIVE
S-ADENOSYL-L-METHION
INE-DEPENDENT
METHYLTRANSFERASE)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 12 GLY A  35
GLY A  37
SER A  61
ASP A  86
VAL A  87
 NAP  A 401 (-3.5A)
NAP  A 401 ( 4.9A)
NAP  A 401 (-4.4A)
NAP  A 401 (-3.2A)
NAP  A 401 (-3.6A)
 0.83A 3dlcA-4fc7A:
6.1		 3dlcA-4fc7A:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL9_A_DR7A100_2
(PROTEASE)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ASP A 137
GLY A 116
ALA A 115
ILE A  40
GLY A 216
 None
COA  A 402 (-3.5A)
NAP  A 401 (-3.2A)
NAP  A 401 (-4.0A)
NAP  A 401 (-3.2A)
 1.05A 3el9B-4fc7A:
undetectable		 3el9B-4fc7A:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_A_THHA642_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 12 GLY A 213
VAL A 249
GLY A  41
SER A  38
ILE A  40
 None
None
None
NAP  A 401 (-2.7A)
NAP  A 401 (-4.0A)
 1.20A 3k13A-4fc7A:
undetectable		 3k13A-4fc7A:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_B_THHB643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 12 GLY A 213
VAL A 249
GLY A  41
SER A  38
ILE A  40
 None
None
None
NAP  A 401 (-2.7A)
NAP  A 401 (-4.0A)
 1.19A 3k13B-4fc7A:
3.4		 3k13B-4fc7A:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_C_THHC643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 12 GLY A 213
VAL A 249
GLY A  41
SER A  38
ILE A  40
 None
None
None
NAP  A 401 (-2.7A)
NAP  A 401 (-4.0A)
 1.19A 3k13C-4fc7A:
2.0		 3k13C-4fc7A:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDT_B_VORB506_1
(CHOLESTEROL
24-HYDROXYLASE)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 11 VAL A 144
SER A 145
ILE A 109
ALA A 100
ALA A  31
 None
 1.09A 3mdtB-4fc7A:
undetectable		 3mdtB-4fc7A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KRH_A_SAMA900_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE
2)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 12 GLY A  35
GLY A  37
SER A  61
ASP A  86
ILE A 136
 NAP  A 401 (-3.5A)
NAP  A 401 ( 4.9A)
NAP  A 401 (-4.4A)
NAP  A 401 (-3.2A)
NAP  A 401 (-3.8A)
 0.85A 4krhA-4fc7A:
7.0		 4krhA-4fc7A:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1X_A_017A101_1
(ASPARTYL PROTEASE)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 11 ASP A 137
GLY A 116
ALA A 115
ILE A 163
ILE A  40
 None
COA  A 402 (-3.5A)
NAP  A 401 (-3.2A)
NAP  A 401 (-4.6A)
NAP  A 401 (-4.0A)
 0.89A 4q1xA-4fc7A:
undetectable		 4q1xA-4fc7A:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_B_SAMB301_0
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 12 GLY A  35
GLY A  37
SER A  61
ILE A  40
ARG A  88
 NAP  A 401 (-3.5A)
NAP  A 401 ( 4.9A)
NAP  A 401 (-4.4A)
NAP  A 401 (-4.0A)
COA  A 402 ( 2.8A)
 1.13A 4qtuB-4fc7A:
6.4		 4qtuB-4fc7A:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 11 SER A 248
THR A 166
THR A 164
GLY A 209
ALA A 267
 None
 1.43A 4qvlV-4fc7A:
undetectable
4qvlb-4fc7A:
undetectable		 4qvlV-4fc7A:
20.42
4qvlb-4fc7A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 11 SER A 248
THR A 166
THR A 164
GLY A 209
ALA A 267
 None
 1.42A 4qvlH-4fc7A:
undetectable
4qvlN-4fc7A:
undetectable		 4qvlH-4fc7A:
20.42
4qvlN-4fc7A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 11 SER A 248
THR A 166
THR A 164
GLY A 209
ALA A 267
 None
 1.42A 4qvmV-4fc7A:
undetectable
4qvmb-4fc7A:
undetectable		 4qvmV-4fc7A:
20.42
4qvmb-4fc7A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 11 SER A 248
THR A 166
THR A 164
GLY A 209
ALA A 267
 None
 1.43A 4qvmH-4fc7A:
undetectable
4qvmN-4fc7A:
undetectable		 4qvmH-4fc7A:
20.42
4qvmN-4fc7A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 11 SER A 248
THR A 166
THR A 164
GLY A 209
ALA A 267
 None
 1.42A 4qvpV-4fc7A:
undetectable
4qvpb-4fc7A:
undetectable		 4qvpV-4fc7A:
20.42
4qvpb-4fc7A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 11 SER A 248
THR A 166
THR A 164
GLY A 209
ALA A 267
 None
 1.42A 4qvpH-4fc7A:
undetectable
4qvpN-4fc7A:
undetectable		 4qvpH-4fc7A:
20.42
4qvpN-4fc7A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 11 SER A 248
THR A 166
THR A 164
GLY A 209
ALA A 267
 None
 1.42A 4qvqV-4fc7A:
undetectable
4qvqb-4fc7A:
undetectable		 4qvqV-4fc7A:
20.42
4qvqb-4fc7A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVQ_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 11 SER A 248
THR A 166
THR A 164
GLY A 209
ALA A 267
 None
 1.43A 4qvqH-4fc7A:
undetectable
4qvqN-4fc7A:
undetectable		 4qvqH-4fc7A:
20.42
4qvqN-4fc7A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 11 SER A 248
THR A 166
THR A 164
GLY A 209
ALA A 267
 None
 1.43A 4qvwV-4fc7A:
undetectable
4qvwb-4fc7A:
undetectable		 4qvwV-4fc7A:
20.42
4qvwb-4fc7A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 11 SER A 248
THR A 166
THR A 164
GLY A 209
ALA A 267
 None
 1.43A 4qvwH-4fc7A:
undetectable
4qvwN-4fc7A:
undetectable		 4qvwH-4fc7A:
20.42
4qvwN-4fc7A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 11 SER A 248
THR A 166
THR A 164
GLY A 209
ALA A 267
 None
 1.43A 4qw0V-4fc7A:
undetectable
4qw0b-4fc7A:
undetectable		 4qw0V-4fc7A:
20.42
4qw0b-4fc7A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW0_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 11 SER A 248
THR A 166
THR A 164
GLY A 209
ALA A 267
 None
 1.43A 4qw0H-4fc7A:
undetectable
4qw0N-4fc7A:
undetectable		 4qw0H-4fc7A:
20.42
4qw0N-4fc7A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 11 SER A 248
THR A 166
THR A 164
GLY A 209
ALA A 267
 None
 1.43A 4qw1V-4fc7A:
undetectable
4qw1b-4fc7A:
undetectable		 4qw1V-4fc7A:
20.42
4qw1b-4fc7A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 11 SER A 248
THR A 166
THR A 164
GLY A 209
ALA A 267
 None
 1.43A 4qw1H-4fc7A:
undetectable
4qw1N-4fc7A:
undetectable		 4qw1H-4fc7A:
20.42
4qw1N-4fc7A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 11 SER A 248
THR A 166
THR A 164
GLY A 209
ALA A 267
 None
 1.43A 4qw3V-4fc7A:
undetectable
4qw3b-4fc7A:
undetectable		 4qw3V-4fc7A:
20.42
4qw3b-4fc7A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 11 SER A 248
THR A 166
THR A 164
GLY A 209
ALA A 267
 None
 1.43A 4qw3H-4fc7A:
undetectable
4qw3N-4fc7A:
undetectable		 4qw3H-4fc7A:
20.42
4qw3N-4fc7A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 11 SER A 248
THR A 166
THR A 164
GLY A 209
ALA A 267
 None
 1.43A 4qwuV-4fc7A:
undetectable
4qwub-4fc7A:
undetectable		 4qwuV-4fc7A:
20.42
4qwub-4fc7A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWU_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 11 SER A 248
THR A 166
THR A 164
GLY A 209
ALA A 267
 None
 1.43A 4qwuH-4fc7A:
undetectable
4qwuN-4fc7A:
undetectable		 4qwuH-4fc7A:
20.42
4qwuN-4fc7A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 11 SER A 248
THR A 166
THR A 164
GLY A 209
ALA A 267
 None
 1.40A 5bxnV-4fc7A:
undetectable
5bxnb-4fc7A:
undetectable		 5bxnV-4fc7A:
20.42
5bxnb-4fc7A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 11 SER A 248
THR A 166
THR A 164
GLY A 209
ALA A 267
 None
 1.40A 5bxnH-4fc7A:
undetectable
5bxnN-4fc7A:
undetectable		 5bxnH-4fc7A:
20.42
5bxnN-4fc7A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CZ7_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 11 SER A 248
THR A 166
THR A 164
GLY A 209
ALA A 267
 None
 1.43A 5cz7H-4fc7A:
undetectable
5cz7N-4fc7A:
undetectable		 5cz7H-4fc7A:
20.42
5cz7N-4fc7A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 11 SER A 248
THR A 166
THR A 164
GLY A 209
ALA A 267
 None
 1.43A 5d0xV-4fc7A:
undetectable
5d0xb-4fc7A:
undetectable		 5d0xV-4fc7A:
20.42
5d0xb-4fc7A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 11 SER A 248
THR A 166
THR A 164
GLY A 209
ALA A 267
 None
 1.43A 5d0xH-4fc7A:
undetectable
5d0xN-4fc7A:
undetectable		 5d0xH-4fc7A:
20.42
5d0xN-4fc7A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.17A 5eeuA-4fc7A:
undetectable
5eeuB-4fc7A:
undetectable		 5eeuA-4fc7A:
16.60
5eeuB-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.18A 5eeuB-4fc7A:
undetectable
5eeuC-4fc7A:
undetectable		 5eeuB-4fc7A:
16.60
5eeuC-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.18A 5eeuC-4fc7A:
undetectable
5eeuD-4fc7A:
undetectable		 5eeuC-4fc7A:
16.60
5eeuD-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.16A 5eeuD-4fc7A:
undetectable
5eeuE-4fc7A:
undetectable		 5eeuD-4fc7A:
16.60
5eeuE-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.15A 5eeuE-4fc7A:
undetectable
5eeuF-4fc7A:
undetectable		 5eeuE-4fc7A:
16.60
5eeuF-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.20A 5eeuG-4fc7A:
undetectable
5eeuH-4fc7A:
undetectable		 5eeuG-4fc7A:
16.60
5eeuH-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.17A 5eeuH-4fc7A:
undetectable
5eeuI-4fc7A:
undetectable		 5eeuH-4fc7A:
16.60
5eeuI-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 12 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.16A 5eeuI-4fc7A:
undetectable
5eeuJ-4fc7A:
undetectable		 5eeuI-4fc7A:
16.60
5eeuJ-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.22A 5eeuJ-4fc7A:
undetectable
5eeuK-4fc7A:
undetectable		 5eeuJ-4fc7A:
16.60
5eeuK-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.19A 5eeuA-4fc7A:
undetectable
5eeuK-4fc7A:
undetectable		 5eeuA-4fc7A:
16.60
5eeuK-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.25A 5eeuN-4fc7A:
undetectable
5eeuO-4fc7A:
undetectable		 5eeuN-4fc7A:
16.60
5eeuO-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.23A 5eeuP-4fc7A:
undetectable
5eeuQ-4fc7A:
undetectable		 5eeuP-4fc7A:
16.60
5eeuQ-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.23A 5eeuR-4fc7A:
undetectable
5eeuS-4fc7A:
undetectable		 5eeuR-4fc7A:
16.60
5eeuS-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.19A 5eeuS-4fc7A:
undetectable
5eeuT-4fc7A:
undetectable		 5eeuS-4fc7A:
16.60
5eeuT-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.23A 5eeuT-4fc7A:
undetectable
5eeuU-4fc7A:
undetectable		 5eeuT-4fc7A:
16.60
5eeuU-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.21A 5eeuU-4fc7A:
undetectable
5eeuV-4fc7A:
undetectable		 5eeuU-4fc7A:
16.60
5eeuV-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.17A 5eevB-4fc7A:
undetectable
5eevC-4fc7A:
undetectable		 5eevB-4fc7A:
16.60
5eevC-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.18A 5eevC-4fc7A:
undetectable
5eevD-4fc7A:
undetectable		 5eevC-4fc7A:
16.60
5eevD-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.16A 5eevD-4fc7A:
undetectable
5eevE-4fc7A:
undetectable		 5eevD-4fc7A:
16.60
5eevE-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.15A 5eevE-4fc7A:
undetectable
5eevF-4fc7A:
undetectable		 5eevE-4fc7A:
16.60
5eevF-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.20A 5eevG-4fc7A:
undetectable
5eevH-4fc7A:
undetectable		 5eevG-4fc7A:
16.60
5eevH-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.17A 5eevH-4fc7A:
undetectable
5eevI-4fc7A:
undetectable		 5eevH-4fc7A:
16.60
5eevI-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 12 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.16A 5eevI-4fc7A:
undetectable
5eevJ-4fc7A:
undetectable		 5eevI-4fc7A:
16.60
5eevJ-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.22A 5eevJ-4fc7A:
undetectable
5eevK-4fc7A:
undetectable		 5eevJ-4fc7A:
16.60
5eevK-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.19A 5eevA-4fc7A:
undetectable
5eevK-4fc7A:
undetectable		 5eevA-4fc7A:
16.60
5eevK-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.25A 5eevN-4fc7A:
undetectable
5eevO-4fc7A:
undetectable		 5eevN-4fc7A:
16.60
5eevO-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.24A 5eevP-4fc7A:
undetectable
5eevQ-4fc7A:
undetectable		 5eevP-4fc7A:
16.60
5eevQ-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.23A 5eevR-4fc7A:
undetectable
5eevS-4fc7A:
undetectable		 5eevR-4fc7A:
16.60
5eevS-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.19A 5eevS-4fc7A:
undetectable
5eevT-4fc7A:
undetectable		 5eevS-4fc7A:
16.60
5eevT-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.22A 5eevT-4fc7A:
undetectable
5eevU-4fc7A:
undetectable		 5eevT-4fc7A:
16.60
5eevU-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.21A 5eevU-4fc7A:
undetectable
5eevV-4fc7A:
undetectable		 5eevU-4fc7A:
16.60
5eevV-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.17A 5eewA-4fc7A:
undetectable
5eewB-4fc7A:
undetectable		 5eewA-4fc7A:
16.60
5eewB-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.17A 5eewB-4fc7A:
undetectable
5eewC-4fc7A:
undetectable		 5eewB-4fc7A:
16.60
5eewC-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.18A 5eewC-4fc7A:
undetectable
5eewD-4fc7A:
undetectable		 5eewC-4fc7A:
16.60
5eewD-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.16A 5eewD-4fc7A:
undetectable
5eewE-4fc7A:
undetectable		 5eewD-4fc7A:
16.60
5eewE-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.15A 5eewE-4fc7A:
undetectable
5eewF-4fc7A:
undetectable		 5eewE-4fc7A:
16.60
5eewF-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.20A 5eewG-4fc7A:
undetectable
5eewH-4fc7A:
undetectable		 5eewG-4fc7A:
16.60
5eewH-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.17A 5eewH-4fc7A:
undetectable
5eewI-4fc7A:
undetectable		 5eewH-4fc7A:
16.60
5eewI-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 12 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.16A 5eewI-4fc7A:
undetectable
5eewJ-4fc7A:
undetectable		 5eewI-4fc7A:
16.60
5eewJ-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.22A 5eewJ-4fc7A:
undetectable
5eewK-4fc7A:
undetectable		 5eewJ-4fc7A:
16.60
5eewK-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.19A 5eewA-4fc7A:
undetectable
5eewK-4fc7A:
undetectable		 5eewA-4fc7A:
16.60
5eewK-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.24A 5eewN-4fc7A:
undetectable
5eewO-4fc7A:
undetectable		 5eewN-4fc7A:
16.60
5eewO-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.24A 5eewP-4fc7A:
undetectable
5eewQ-4fc7A:
undetectable		 5eewP-4fc7A:
16.60
5eewQ-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.23A 5eewR-4fc7A:
undetectable
5eewS-4fc7A:
undetectable		 5eewR-4fc7A:
16.60
5eewS-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.19A 5eewS-4fc7A:
undetectable
5eewT-4fc7A:
undetectable		 5eewS-4fc7A:
16.60
5eewT-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.23A 5eewT-4fc7A:
undetectable
5eewU-4fc7A:
undetectable		 5eewT-4fc7A:
16.60
5eewU-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.21A 5eewU-4fc7A:
undetectable
5eewV-4fc7A:
undetectable		 5eewU-4fc7A:
16.60
5eewV-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.17A 5eexA-4fc7A:
undetectable
5eexB-4fc7A:
undetectable		 5eexA-4fc7A:
16.60
5eexB-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.17A 5eexB-4fc7A:
undetectable
5eexC-4fc7A:
undetectable		 5eexB-4fc7A:
16.60
5eexC-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.18A 5eexC-4fc7A:
undetectable
5eexD-4fc7A:
undetectable		 5eexC-4fc7A:
16.60
5eexD-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.16A 5eexD-4fc7A:
undetectable
5eexE-4fc7A:
undetectable		 5eexD-4fc7A:
16.60
5eexE-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.15A 5eexE-4fc7A:
undetectable
5eexF-4fc7A:
undetectable		 5eexE-4fc7A:
16.60
5eexF-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.20A 5eexG-4fc7A:
undetectable
5eexH-4fc7A:
undetectable		 5eexG-4fc7A:
16.60
5eexH-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.17A 5eexH-4fc7A:
undetectable
5eexI-4fc7A:
undetectable		 5eexH-4fc7A:
16.60
5eexI-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 11 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.16A 5eexI-4fc7A:
undetectable
5eexJ-4fc7A:
undetectable		 5eexI-4fc7A:
16.60
5eexJ-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.22A 5eexJ-4fc7A:
undetectable
5eexK-4fc7A:
undetectable		 5eexJ-4fc7A:
16.60
5eexK-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.19A 5eexA-4fc7A:
undetectable
5eexK-4fc7A:
undetectable		 5eexA-4fc7A:
16.60
5eexK-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.24A 5eexN-4fc7A:
undetectable
5eexO-4fc7A:
undetectable		 5eexN-4fc7A:
16.60
5eexO-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.23A 5eexP-4fc7A:
undetectable
5eexQ-4fc7A:
undetectable		 5eexP-4fc7A:
16.60
5eexQ-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.24A 5eexQ-4fc7A:
undetectable
5eexR-4fc7A:
undetectable		 5eexQ-4fc7A:
16.60
5eexR-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.23A 5eexR-4fc7A:
undetectable
5eexS-4fc7A:
undetectable		 5eexR-4fc7A:
16.60
5eexS-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.19A 5eexS-4fc7A:
undetectable
5eexT-4fc7A:
undetectable		 5eexS-4fc7A:
16.60
5eexT-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.22A 5eexT-4fc7A:
undetectable
5eexU-4fc7A:
undetectable		 5eexT-4fc7A:
16.60
5eexU-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.21A 5eexU-4fc7A:
undetectable
5eexV-4fc7A:
undetectable		 5eexU-4fc7A:
16.60
5eexV-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.17A 5eeyA-4fc7A:
undetectable
5eeyB-4fc7A:
undetectable		 5eeyA-4fc7A:
16.60
5eeyB-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.18A 5eeyB-4fc7A:
undetectable
5eeyC-4fc7A:
undetectable		 5eeyB-4fc7A:
16.60
5eeyC-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.18A 5eeyC-4fc7A:
undetectable
5eeyD-4fc7A:
undetectable		 5eeyC-4fc7A:
16.60
5eeyD-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.16A 5eeyD-4fc7A:
undetectable
5eeyE-4fc7A:
undetectable		 5eeyD-4fc7A:
16.60
5eeyE-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.15A 5eeyE-4fc7A:
undetectable
5eeyF-4fc7A:
undetectable		 5eeyE-4fc7A:
16.60
5eeyF-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.20A 5eeyG-4fc7A:
undetectable
5eeyH-4fc7A:
undetectable		 5eeyG-4fc7A:
16.60
5eeyH-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.17A 5eeyH-4fc7A:
undetectable
5eeyI-4fc7A:
undetectable		 5eeyH-4fc7A:
16.60
5eeyI-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 11 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.16A 5eeyI-4fc7A:
undetectable
5eeyJ-4fc7A:
undetectable		 5eeyI-4fc7A:
16.60
5eeyJ-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.22A 5eeyJ-4fc7A:
undetectable
5eeyK-4fc7A:
undetectable		 5eeyJ-4fc7A:
16.60
5eeyK-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.19A 5eeyA-4fc7A:
undetectable
5eeyK-4fc7A:
undetectable		 5eeyA-4fc7A:
16.60
5eeyK-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.24A 5eeyN-4fc7A:
undetectable
5eeyO-4fc7A:
undetectable		 5eeyN-4fc7A:
16.60
5eeyO-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.23A 5eeyP-4fc7A:
undetectable
5eeyQ-4fc7A:
undetectable		 5eeyP-4fc7A:
16.60
5eeyQ-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.25A 5eeyQ-4fc7A:
undetectable
5eeyR-4fc7A:
undetectable		 5eeyQ-4fc7A:
16.60
5eeyR-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.23A 5eeyR-4fc7A:
undetectable
5eeyS-4fc7A:
undetectable		 5eeyR-4fc7A:
16.60
5eeyS-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.19A 5eeyS-4fc7A:
undetectable
5eeyT-4fc7A:
undetectable		 5eeyS-4fc7A:
16.60
5eeyT-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.23A 5eeyT-4fc7A:
undetectable
5eeyU-4fc7A:
undetectable		 5eeyT-4fc7A:
16.60
5eeyU-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.21A 5eeyU-4fc7A:
undetectable
5eeyV-4fc7A:
undetectable		 5eeyU-4fc7A:
16.60
5eeyV-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.17A 5eezA-4fc7A:
undetectable
5eezB-4fc7A:
undetectable		 5eezA-4fc7A:
16.60
5eezB-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.18A 5eezB-4fc7A:
undetectable
5eezC-4fc7A:
undetectable		 5eezB-4fc7A:
16.60
5eezC-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.18A 5eezC-4fc7A:
undetectable
5eezD-4fc7A:
undetectable		 5eezC-4fc7A:
16.60
5eezD-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.16A 5eezD-4fc7A:
undetectable
5eezE-4fc7A:
undetectable		 5eezD-4fc7A:
16.60
5eezE-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.15A 5eezE-4fc7A:
undetectable
5eezF-4fc7A:
undetectable		 5eezE-4fc7A:
16.60
5eezF-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.20A 5eezG-4fc7A:
undetectable
5eezH-4fc7A:
undetectable		 5eezG-4fc7A:
16.60
5eezH-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.17A 5eezH-4fc7A:
undetectable
5eezI-4fc7A:
undetectable		 5eezH-4fc7A:
16.60
5eezI-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 11 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.16A 5eezI-4fc7A:
undetectable
5eezJ-4fc7A:
undetectable		 5eezI-4fc7A:
16.60
5eezJ-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.23A 5eezJ-4fc7A:
undetectable
5eezK-4fc7A:
undetectable		 5eezJ-4fc7A:
16.60
5eezK-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.19A 5eezA-4fc7A:
undetectable
5eezK-4fc7A:
undetectable		 5eezA-4fc7A:
16.60
5eezK-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.24A 5eezN-4fc7A:
undetectable
5eezO-4fc7A:
undetectable		 5eezN-4fc7A:
16.60
5eezO-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.23A 5eezP-4fc7A:
undetectable
5eezQ-4fc7A:
undetectable		 5eezP-4fc7A:
16.60
5eezQ-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.25A 5eezQ-4fc7A:
undetectable
5eezR-4fc7A:
undetectable		 5eezQ-4fc7A:
16.60
5eezR-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.23A 5eezR-4fc7A:
undetectable
5eezS-4fc7A:
undetectable		 5eezR-4fc7A:
16.60
5eezS-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.19A 5eezS-4fc7A:
undetectable
5eezT-4fc7A:
undetectable		 5eezS-4fc7A:
16.60
5eezT-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.23A 5eezT-4fc7A:
undetectable
5eezU-4fc7A:
undetectable		 5eezT-4fc7A:
16.60
5eezU-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.21A 5eezU-4fc7A:
undetectable
5eezV-4fc7A:
undetectable		 5eezU-4fc7A:
16.60
5eezV-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.17A 5ef0B-4fc7A:
undetectable
5ef0C-4fc7A:
undetectable		 5ef0B-4fc7A:
16.60
5ef0C-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.18A 5ef0C-4fc7A:
undetectable
5ef0D-4fc7A:
undetectable		 5ef0C-4fc7A:
16.60
5ef0D-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.16A 5ef0D-4fc7A:
undetectable
5ef0E-4fc7A:
undetectable		 5ef0D-4fc7A:
16.60
5ef0E-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.15A 5ef0E-4fc7A:
undetectable
5ef0F-4fc7A:
undetectable		 5ef0E-4fc7A:
16.60
5ef0F-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.20A 5ef0G-4fc7A:
undetectable
5ef0H-4fc7A:
undetectable		 5ef0G-4fc7A:
16.60
5ef0H-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.17A 5ef0H-4fc7A:
undetectable
5ef0I-4fc7A:
undetectable		 5ef0H-4fc7A:
16.60
5ef0I-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 11 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.16A 5ef0I-4fc7A:
undetectable
5ef0J-4fc7A:
undetectable		 5ef0I-4fc7A:
16.60
5ef0J-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.22A 5ef0J-4fc7A:
undetectable
5ef0K-4fc7A:
undetectable		 5ef0J-4fc7A:
16.60
5ef0K-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.19A 5ef0A-4fc7A:
undetectable
5ef0K-4fc7A:
undetectable		 5ef0A-4fc7A:
16.60
5ef0K-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.24A 5ef0N-4fc7A:
undetectable
5ef0O-4fc7A:
undetectable		 5ef0N-4fc7A:
16.60
5ef0O-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.24A 5ef0P-4fc7A:
undetectable
5ef0Q-4fc7A:
undetectable		 5ef0P-4fc7A:
16.60
5ef0Q-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.25A 5ef0Q-4fc7A:
undetectable
5ef0R-4fc7A:
undetectable		 5ef0Q-4fc7A:
16.60
5ef0R-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.23A 5ef0R-4fc7A:
undetectable
5ef0S-4fc7A:
undetectable		 5ef0R-4fc7A:
16.60
5ef0S-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.19A 5ef0S-4fc7A:
undetectable
5ef0T-4fc7A:
undetectable		 5ef0S-4fc7A:
16.60
5ef0T-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.22A 5ef0T-4fc7A:
undetectable
5ef0U-4fc7A:
undetectable		 5ef0T-4fc7A:
16.60
5ef0U-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.21A 5ef0U-4fc7A:
undetectable
5ef0V-4fc7A:
undetectable		 5ef0U-4fc7A:
16.60
5ef0V-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.18A 5ef1B-4fc7A:
undetectable
5ef1C-4fc7A:
undetectable		 5ef1B-4fc7A:
16.60
5ef1C-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.18A 5ef1C-4fc7A:
undetectable
5ef1D-4fc7A:
undetectable		 5ef1C-4fc7A:
16.60
5ef1D-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.16A 5ef1D-4fc7A:
undetectable
5ef1E-4fc7A:
undetectable		 5ef1D-4fc7A:
16.60
5ef1E-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.16A 5ef1E-4fc7A:
undetectable
5ef1F-4fc7A:
undetectable		 5ef1E-4fc7A:
16.60
5ef1F-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.20A 5ef1G-4fc7A:
undetectable
5ef1H-4fc7A:
undetectable		 5ef1G-4fc7A:
16.60
5ef1H-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.17A 5ef1H-4fc7A:
undetectable
5ef1I-4fc7A:
undetectable		 5ef1H-4fc7A:
16.60
5ef1I-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 11 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.16A 5ef1I-4fc7A:
undetectable
5ef1J-4fc7A:
undetectable		 5ef1I-4fc7A:
16.60
5ef1J-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.22A 5ef1J-4fc7A:
undetectable
5ef1K-4fc7A:
undetectable		 5ef1J-4fc7A:
16.60
5ef1K-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.19A 5ef1A-4fc7A:
undetectable
5ef1K-4fc7A:
undetectable		 5ef1A-4fc7A:
16.60
5ef1K-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.24A 5ef1N-4fc7A:
undetectable
5ef1O-4fc7A:
undetectable		 5ef1N-4fc7A:
16.60
5ef1O-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.24A 5ef1P-4fc7A:
undetectable
5ef1Q-4fc7A:
undetectable		 5ef1P-4fc7A:
16.60
5ef1Q-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.25A 5ef1Q-4fc7A:
undetectable
5ef1R-4fc7A:
undetectable		 5ef1Q-4fc7A:
16.60
5ef1R-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.23A 5ef1R-4fc7A:
undetectable
5ef1S-4fc7A:
undetectable		 5ef1R-4fc7A:
16.60
5ef1S-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.18A 5ef1S-4fc7A:
undetectable
5ef1T-4fc7A:
undetectable		 5ef1S-4fc7A:
16.60
5ef1T-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.23A 5ef1T-4fc7A:
undetectable
5ef1U-4fc7A:
undetectable		 5ef1T-4fc7A:
16.60
5ef1U-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.21A 5ef1U-4fc7A:
undetectable
5ef1V-4fc7A:
undetectable		 5ef1U-4fc7A:
16.60
5ef1V-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.17A 5ef2A-4fc7A:
undetectable
5ef2B-4fc7A:
undetectable		 5ef2A-4fc7A:
16.60
5ef2B-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.18A 5ef2B-4fc7A:
undetectable
5ef2C-4fc7A:
undetectable		 5ef2B-4fc7A:
16.60
5ef2C-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.18A 5ef2C-4fc7A:
undetectable
5ef2D-4fc7A:
undetectable		 5ef2C-4fc7A:
16.60
5ef2D-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.16A 5ef2D-4fc7A:
undetectable
5ef2E-4fc7A:
undetectable		 5ef2D-4fc7A:
16.60
5ef2E-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.16A 5ef2E-4fc7A:
undetectable
5ef2F-4fc7A:
undetectable		 5ef2E-4fc7A:
16.60
5ef2F-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.20A 5ef2G-4fc7A:
undetectable
5ef2H-4fc7A:
undetectable		 5ef2G-4fc7A:
16.60
5ef2H-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.17A 5ef2H-4fc7A:
undetectable
5ef2I-4fc7A:
undetectable		 5ef2H-4fc7A:
16.60
5ef2I-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 11 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.16A 5ef2I-4fc7A:
undetectable
5ef2J-4fc7A:
undetectable		 5ef2I-4fc7A:
16.60
5ef2J-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.23A 5ef2J-4fc7A:
undetectable
5ef2K-4fc7A:
undetectable		 5ef2J-4fc7A:
16.60
5ef2K-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.19A 5ef2A-4fc7A:
undetectable
5ef2K-4fc7A:
undetectable		 5ef2A-4fc7A:
16.60
5ef2K-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.24A 5ef2N-4fc7A:
undetectable
5ef2O-4fc7A:
undetectable		 5ef2N-4fc7A:
16.60
5ef2O-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.24A 5ef2P-4fc7A:
undetectable
5ef2Q-4fc7A:
undetectable		 5ef2P-4fc7A:
16.60
5ef2Q-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.25A 5ef2Q-4fc7A:
undetectable
5ef2R-4fc7A:
undetectable		 5ef2Q-4fc7A:
16.60
5ef2R-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.23A 5ef2R-4fc7A:
undetectable
5ef2S-4fc7A:
undetectable		 5ef2R-4fc7A:
16.60
5ef2S-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.19A 5ef2S-4fc7A:
undetectable
5ef2T-4fc7A:
undetectable		 5ef2S-4fc7A:
16.60
5ef2T-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.22A 5ef2T-4fc7A:
undetectable
5ef2U-4fc7A:
undetectable		 5ef2T-4fc7A:
16.60
5ef2U-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.21A 5ef2U-4fc7A:
undetectable
5ef2V-4fc7A:
undetectable		 5ef2U-4fc7A:
16.60
5ef2V-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.18A 5ef3B-4fc7A:
undetectable
5ef3C-4fc7A:
undetectable		 5ef3B-4fc7A:
16.60
5ef3C-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.18A 5ef3C-4fc7A:
undetectable
5ef3D-4fc7A:
undetectable		 5ef3C-4fc7A:
16.60
5ef3D-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.16A 5ef3D-4fc7A:
undetectable
5ef3E-4fc7A:
undetectable		 5ef3D-4fc7A:
16.60
5ef3E-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.16A 5ef3E-4fc7A:
undetectable
5ef3F-4fc7A:
undetectable		 5ef3E-4fc7A:
16.60
5ef3F-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.20A 5ef3G-4fc7A:
undetectable
5ef3H-4fc7A:
undetectable		 5ef3G-4fc7A:
16.60
5ef3H-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.17A 5ef3H-4fc7A:
undetectable
5ef3I-4fc7A:
undetectable		 5ef3H-4fc7A:
16.60
5ef3I-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 11 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.16A 5ef3I-4fc7A:
undetectable
5ef3J-4fc7A:
undetectable		 5ef3I-4fc7A:
16.60
5ef3J-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 THR A  76
ALA A  69
HIS A  54
THR A  55
ILE A  57
 None
 1.22A 5ef3J-4fc7A:
undetectable
5ef3K-4fc7A:
undetectable		 5ef3J-4fc7A:
16.60
5ef3K-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.20A 5ef3A-4fc7A:
undetectable
5ef3K-4fc7A:
undetectable		 5ef3A-4fc7A:
16.60
5ef3K-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.24A 5ef3N-4fc7A:
undetectable
5ef3O-4fc7A:
undetectable		 5ef3N-4fc7A:
16.60
5ef3O-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.24A 5ef3P-4fc7A:
undetectable
5ef3Q-4fc7A:
undetectable		 5ef3P-4fc7A:
16.60
5ef3Q-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 9 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.25A 5ef3Q-4fc7A:
undetectable
5ef3R-4fc7A:
undetectable		 5ef3Q-4fc7A:
16.60
5ef3R-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.23A 5ef3R-4fc7A:
undetectable
5ef3S-4fc7A:
undetectable		 5ef3R-4fc7A:
16.60
5ef3S-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.19A 5ef3S-4fc7A:
undetectable
5ef3T-4fc7A:
undetectable		 5ef3S-4fc7A:
16.60
5ef3T-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.23A 5ef3T-4fc7A:
undetectable
5ef3U-4fc7A:
undetectable		 5ef3T-4fc7A:
16.60
5ef3U-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ALA A  69
HIS A  54
THR A  55
ILE A  57
THR A  76
 None
 1.21A 5ef3U-4fc7A:
undetectable
5ef3V-4fc7A:
undetectable		 5ef3U-4fc7A:
16.60
5ef3V-4fc7A:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKW_A_TESA601_1
(AROMATASE)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 11 ILE A 163
THR A 189
VAL A 264
VAL A 266
LEU A 252
 NAP  A 401 (-4.6A)
None
None
None
None
 1.29A 5jkwA-4fc7A:
undetectable		 5jkwA-4fc7A:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 11 SER A 248
THR A 166
THR A 164
GLY A 209
ALA A 267
 None
 1.43A 5l66V-4fc7A:
undetectable
5l66b-4fc7A:
undetectable		 5l66V-4fc7A:
20.42
5l66b-4fc7A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A 166
THR A 164
GLY A 209
ALA A 267
SER A 248
 None
 1.43A 5l66K-4fc7A:
undetectable
5l66L-4fc7A:
undetectable		 5l66K-4fc7A:
21.03
5l66L-4fc7A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 11 SER A 248
THR A 166
THR A 164
GLY A 209
ALA A 267
 None
 1.42A 5l66H-4fc7A:
undetectable
5l66N-4fc7A:
undetectable		 5l66H-4fc7A:
20.42
5l66N-4fc7A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L66_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 THR A 166
THR A 164
GLY A 209
ALA A 267
SER A 248
 None
 1.44A 5l66Y-4fc7A:
undetectable
5l66Z-4fc7A:
undetectable		 5l66Y-4fc7A:
21.03
5l66Z-4fc7A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUK_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 LYS A 242
ILE A 245
ILE A 163
VAL A 161
ALA A  31
 None
None
NAP  A 401 (-4.6A)
None
None
 1.18A 5nukA-4fc7A:
undetectable		 5nukA-4fc7A:
13.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 12 ILE A  40
GLY A  41
GLY A  35
LEU A 206
SER A 205
 NAP  A 401 (-4.0A)
None
NAP  A 401 (-3.5A)
None
None
 0.99A 5twjA-4fc7A:
undetectable		 5twjA-4fc7A:
26.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_B_SAMB201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 10 ILE A  40
GLY A  41
GLY A  35
LEU A 206
SER A 205
 NAP  A 401 (-4.0A)
None
NAP  A 401 (-3.5A)
None
None
 1.03A 5twjB-4fc7A:
undetectable		 5twjB-4fc7A:
26.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_E_C2FE3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		6 / 12 ARG A 218
GLY A  10
VAL A 249
GLY A  41
SER A  38
ILE A  40
 None
None
None
None
NAP  A 401 (-2.7A)
NAP  A 401 (-4.0A)
 1.47A 5vooE-4fc7A:
2.9		 5vooE-4fc7A:
23.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA502_1
(CYTOCHROME P450 2C9)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 12 ALA A 207
ASN A 169
GLY A 179
LEU A 119
LEU A 220
 None
 1.43A 5x23A-4fc7A:
undetectable		 5x23A-4fc7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA502_1
(CYTOCHROME P450 2C9)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		5 / 12 ASN A 169
GLY A 179
ALA A 178
LEU A 119
LEU A 220
 None
 1.26A 5x23A-4fc7A:
undetectable		 5x23A-4fc7A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_D_ADND502_1
(ADENOSYLHOMOCYSTEINA
SE)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		3 / 3 LEU A  20
ASN A 241
LEU A  14
 None
 0.77A 6exiD-4fc7A:
8.8		 6exiD-4fc7A:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MXT_A_K5YA1401_1
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 4fc7 PEROXISOMAL
2,4-DIENOYL-COA
REDUCTASE
(Homo
sapiens) 		3 / 3 ASP A  11
SER A  61
SER A  59
 None
NAP  A 401 (-4.4A)
NAP  A 401 (-2.7A)
 0.61A 6mxtA-4fc7A:
undetectable		 6mxtA-4fc7A:
19.16