SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fc9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_A_VIBA502_1
(THIAMIN
PYROPHOSPHOKINASE)		 4fc9 UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		4 / 8 LEU B 533
SER B 514
ASN B 506
ASP B 603
 None
 1.13A 1ig3A-4fc9B:
undetectable
1ig3B-4fc9B:
undetectable		 1ig3A-4fc9B:
26.28
1ig3B-4fc9B:
26.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_B_VIBB501_1
(THIAMIN
PYROPHOSPHOKINASE)		 4fc9 UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		4 / 7 ASP B 603
LEU B 533
SER B 514
ASN B 506
 None
 1.22A 1ig3A-4fc9B:
undetectable
1ig3B-4fc9B:
undetectable		 1ig3A-4fc9B:
26.28
1ig3B-4fc9B:
26.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_B_SAMB500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 4fc9 UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		4 / 8 PHE B 527
SER B 540
ARG B 541
ALA B 532
 None
 1.12A 1rqpC-4fc9B:
undetectable		 1rqpC-4fc9B:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_C_SAMC500_0
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 4fc9 UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		4 / 8 PHE B 527
SER B 540
ARG B 541
ALA B 532
 None
 1.12A 1rqpA-4fc9B:
undetectable		 1rqpA-4fc9B:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_A_SAMA1299_0
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 4fc9 UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		4 / 8 PHE B 527
SER B 540
ARG B 541
ALA B 532
 None
 1.18A 2v7uA-4fc9B:
undetectable		 2v7uA-4fc9B:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_A_29SA601_1
(ESTROGEN RECEPTOR)		 4fc9 UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		5 / 12 THR B 606
ASP B 603
MET B 496
LEU B 497
LEU B 533
 None
 1.21A 4xi3A-4fc9B:
undetectable		 4xi3A-4fc9B:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_A_BEZA502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 4fc9 UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		4 / 6 VAL B 595
LEU B 537
LEU B 585
HIS B 584
 None
 0.97A 6e43A-4fc9B:
undetectable		 6e43A-4fc9B:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_B_BEZB502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 4fc9 UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		4 / 6 VAL B 595
LEU B 537
LEU B 585
HIS B 584
 None
 1.01A 6e43B-4fc9B:
undetectable		 6e43B-4fc9B:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_C_BEZC502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 4fc9 UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		4 / 6 VAL B 595
LEU B 537
LEU B 585
HIS B 584
 None
 0.99A 6e43C-4fc9B:
undetectable		 6e43C-4fc9B:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_D_BEZD502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 4fc9 UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		4 / 6 VAL B 595
LEU B 537
LEU B 585
HIS B 584
 None
 1.02A 6e43D-4fc9B:
undetectable		 6e43D-4fc9B:
20.74