SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fcg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_C_DCFC1353_2
(ADENOSINE DEAMINASE)		 4fcg UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		4 / 5 LEU A 356
LEU A 333
SER A 323
LEU A 292
 None
None
CL  A 503 (-2.9A)
None
 0.84A 1a4lC-4fcgA:
undetectable		 1a4lC-4fcgA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVT_A_FLPA125_1
(TRANSTHYRETIN)		 4fcg UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		4 / 8 ALA A 363
LEU A 340
LEU A 261
LEU A 285
 None
 0.94A 1dvtA-4fcgA:
undetectable
1dvtB-4fcgA:
undetectable		 1dvtA-4fcgA:
14.94
1dvtB-4fcgA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVT_A_FLPA125_1
(TRANSTHYRETIN)		 4fcg UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		5 / 8 LEU A 261
LEU A 285
LEU A 364
LEU A 340
SER A 338
 None
 1.35A 1dvtA-4fcgA:
undetectable
1dvtB-4fcgA:
undetectable		 1dvtA-4fcgA:
14.94
1dvtB-4fcgA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_E_TFPE212_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 4fcg UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		4 / 7 LEU A 261
PHE A 248
MET A 245
SER A 267
 None
 1.15A 1wrlE-4fcgA:
undetectable		 1wrlE-4fcgA:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_A_BEZA1002_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4fcg UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		5 / 10 GLY A 237
LEU A 215
ILE A 233
PHE A 218
LEU A 241
 None
 1.03A 2f8dA-4fcgA:
undetectable		 2f8dA-4fcgA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8D_B_BEZB1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4fcg UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		5 / 10 GLY A 237
LEU A 215
ILE A 233
PHE A 218
LEU A 241
 None
 1.06A 2f8dB-4fcgA:
undetectable		 2f8dB-4fcgA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RIW_A_T44A1395_1
(THYROXINE-BINDING
GLOBULIN)		 4fcg UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		5 / 10 LEU A 228
LEU A 208
LEU A 197
LEU A 225
ARG A 224
 None
 1.19A 2riwA-4fcgA:
undetectable
2riwB-4fcgA:
undetectable		 2riwA-4fcgA:
20.39
2riwB-4fcgA:
8.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN5_A_FUNA1356_1
(THYROXINE-BINDING
GLOBULIN)		 4fcg UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		5 / 11 LEU A 356
LEU A 333
SER A 319
LEU A 320
LEU A 350
 None
 1.06A 2xn5A-4fcgA:
undetectable		 2xn5A-4fcgA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEH_B_DAHB786_1
(PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN)		 4fcg UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		4 / 7 PRO A 291
LEU A 330
GLY A 303
ALA A 293
 None
 0.99A 3tehB-4fcgA:
undetectable		 3tehB-4fcgA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5J_A_08HA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 4fcg UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		4 / 7 PRO A 289
LEU A 285
LEU A 261
ILE A 268
 None
 1.02A 3u5jA-4fcgA:
undetectable		 3u5jA-4fcgA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTA_B_ADNB401_1
(APH(2'')-ID)		 4fcg UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		4 / 8 PRO A 416
ILE A 419
LEU A 422
ILE A 395
 None
 0.96A 4dtaB-4fcgA:
undetectable		 4dtaB-4fcgA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ECK_A_FOLA703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4fcg UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		5 / 12 ALA A 236
LEU A 210
PHE A 218
LEU A 154
VAL A 153
 None
 1.17A 4eckA-4fcgA:
undetectable		 4eckA-4fcgA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA500_2
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 4fcg UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		4 / 4 LEU A 350
LEU A 320
GLN A 308
GLU A 355
 None
 1.21A 4i41A-4fcgA:
undetectable		 4i41A-4fcgA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOV_A_KOVA204_1
(UNCHARACTERIZED
PROTEIN)		 4fcg UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		5 / 12 GLY A 237
ASN A 259
MET A 239
PHE A 218
TYR A 161
 None
 1.29A 4kovA-4fcgA:
undetectable		 4kovA-4fcgA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOW_A_CFXA204_1
(UNCHARACTERIZED
PROTEIN)		 4fcg UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		5 / 12 GLY A 237
ASN A 259
MET A 239
PHE A 218
TYR A 161
 None
 1.32A 4kowA-4fcgA:
undetectable		 4kowA-4fcgA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOX_A_CLSA205_1
(UNCHARACTERIZED
PROTEIN)		 4fcg UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		5 / 11 GLY A 237
ASN A 259
MET A 239
PHE A 218
TYR A 161
 None
 1.29A 4koxA-4fcgA:
undetectable		 4koxA-4fcgA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_1
(THYROXINE-BINDING
GLOBULIN)		 4fcg UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		6 / 10 SER A 341
LEU A 356
LEU A 333
SER A 319
LEU A 320
LEU A 350
 None
 1.44A 4yiaA-4fcgA:
undetectable		 4yiaA-4fcgA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZOW_A_CLMA500_0
(MULTIDRUG
TRANSPORTER MDFA)		 4fcg UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		5 / 11 LEU A 320
LEU A 256
LEU A 274
LEU A 307
LEU A 254
 None
 1.06A 4zowA-4fcgA:
undetectable		 4zowA-4fcgA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MWY_A_YNUA1101_0
(MINERALOCORTICOID
RECEPTOR)		 4fcg UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		5 / 12 LEU A 343
LEU A 320
ALA A 322
LEU A 292
LEU A 350
 None
None
CL  A 503 (-4.4A)
None
None
 1.21A 5mwyA-4fcgA:
undetectable		 5mwyA-4fcgA:
24.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TT3_H_EZLH303_1
(ALPHA-CARBONIC
ANHYDRASE)		 4fcg UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		4 / 8 HIS A 169
LEU A 190
THR A 186
ALA A 189
 None
None
PO4  A 505 ( 3.5A)
None
 0.95A 5tt3H-4fcgA:
undetectable		 5tt3H-4fcgA:
20.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4fcg UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		4 / 7 ILE A 317
LEU A 312
ARG A 262
LEU A 264
 None
 0.78A 5xdqA-4fcgA:
undetectable
5xdqJ-4fcgA:
undetectable		 5xdqA-4fcgA:
19.77
5xdqJ-4fcgA:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4fcg UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		4 / 7 ILE A 317
LEU A 312
ARG A 262
LEU A 264
 None
 0.94A 5zcqA-4fcgA:
undetectable
5zcqJ-4fcgA:
undetectable		 5zcqA-4fcgA:
19.77
5zcqJ-4fcgA:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 4fcg UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		5 / 10 LEU A 398
LEU A 356
ASP A 357
ILE A 395
PRO A 392
 None
 1.45A 6dlzB-4fcgA:
undetectable
6dlzC-4fcgA:
undetectable		 6dlzB-4fcgA:
15.54
6dlzC-4fcgA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 4fcg UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		5 / 10 SER A 323
LEU A 277
LEU A 330
ILE A 268
PRO A 289
 CL  A 503 (-2.9A)
None
None
None
None
 0.82A 6dlzB-4fcgA:
undetectable
6dlzC-4fcgA:
undetectable		 6dlzB-4fcgA:
15.54
6dlzC-4fcgA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 4fcg UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		5 / 11 ILE A 268
PRO A 289
SER A 323
LEU A 277
LEU A 330
 None
None
CL  A 503 (-2.9A)
None
None
 0.82A 6dlzA-4fcgA:
undetectable
6dlzD-4fcgA:
undetectable		 6dlzA-4fcgA:
15.54
6dlzD-4fcgA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 4fcg UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		5 / 11 ILE A 395
PRO A 392
LEU A 398
LEU A 356
ASP A 357
 None
 1.45A 6dlzA-4fcgA:
undetectable
6dlzD-4fcgA:
undetectable		 6dlzA-4fcgA:
15.54
6dlzD-4fcgA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM0_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 4fcg UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		5 / 10 SER A 323
LEU A 277
LEU A 330
ILE A 268
PRO A 289
 CL  A 503 (-2.9A)
None
None
None
None
 0.81A 6dm0B-4fcgA:
undetectable
6dm0C-4fcgA:
undetectable		 6dm0B-4fcgA:
15.54
6dm0C-4fcgA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 4fcg UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		5 / 10 LEU A 398
LEU A 356
ASP A 357
ILE A 395
PRO A 392
 None
 1.45A 6dm1B-4fcgA:
undetectable
6dm1C-4fcgA:
undetectable		 6dm1B-4fcgA:
15.54
6dm1C-4fcgA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 4fcg UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		5 / 10 SER A 323
LEU A 277
LEU A 330
ILE A 268
PRO A 289
 CL  A 503 (-2.9A)
None
None
None
None
 0.82A 6dm1B-4fcgA:
undetectable
6dm1C-4fcgA:
undetectable		 6dm1B-4fcgA:
15.54
6dm1C-4fcgA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 4fcg UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		5 / 11 ILE A 268
PRO A 289
SER A 323
LEU A 277
LEU A 330
 None
None
CL  A 503 (-2.9A)
None
None
 0.81A 6dm1A-4fcgA:
undetectable
6dm1D-4fcgA:
undetectable		 6dm1A-4fcgA:
15.54
6dm1D-4fcgA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 4fcg UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		5 / 11 ILE A 395
PRO A 392
LEU A 398
LEU A 356
ASP A 357
 None
 1.45A 6dm1A-4fcgA:
undetectable
6dm1D-4fcgA:
undetectable		 6dm1A-4fcgA:
15.54
6dm1D-4fcgA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM2_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 4fcg UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		5 / 10 SER A 323
LEU A 277
LEU A 330
ILE A 268
PRO A 289
 CL  A 503 (-2.9A)
None
None
None
None
 0.85A 6dm2B-4fcgA:
undetectable
6dm2C-4fcgA:
undetectable		 6dm2B-4fcgA:
15.54
6dm2C-4fcgA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM2_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 4fcg UNCHARACTERIZED
PROTEIN
(Xanthomonas
euvesicatoria) 		5 / 10 ILE A 268
PRO A 289
SER A 323
LEU A 277
LEU A 330
 None
None
CL  A 503 (-2.9A)
None
None
 0.85A 6dm2A-4fcgA:
undetectable
6dm2D-4fcgA:
undetectable		 6dm2A-4fcgA:
15.54
6dm2D-4fcgA:
15.54