SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fcu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_B_9CRB165_1
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 4fcu 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE
(Acinetobacter
baumannii) 		5 / 12 ILE A  29
VAL A  63
VAL A  97
ALA A  36
ILE A   4
 None
 1.03A 1epbB-4fcuA:
undetectable		 1epbB-4fcuA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_I_URFI2041_1
(URIDINE
PHOSPHORYLASE)		 4fcu 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE
(Acinetobacter
baumannii) 		4 / 8 THR A  49
GLN A  98
ILE A  54
PRO A  19
 None
 0.99A 1rxcI-4fcuA:
undetectable		 1rxcI-4fcuA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 4fcu 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE
(Acinetobacter
baumannii) 		5 / 9 LEU A 213
LEU A 216
ILE A 222
PHE A 156
TYR A 186
 None
 1.15A 2f78A-4fcuA:
undetectable		 2f78A-4fcuA:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9W_A_ACTA170_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 4fcu 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE
(Acinetobacter
baumannii) 		3 / 3 SER A  74
GLY A  75
THR A  76
 None
 0.09A 3k9wA-4fcuA:
2.7		 3k9wA-4fcuA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_A_RBFA201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 4fcu 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE
(Acinetobacter
baumannii) 		4 / 8 THR A  68
VAL A 190
LEU A 193
ILE A  94
 None
 0.70A 4r38A-4fcuA:
undetectable		 4r38A-4fcuA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WBO_C_ANWC601_0
(RHODOPSIN KINASE)		 4fcu 3-DEOXY-MANNO-OCTULO
SONATE
CYTIDYLYLTRANSFERASE
(Acinetobacter
baumannii) 		4 / 6 ARG A 181
LEU A 183
ALA A 227
LEU A 104
 None
 0.89A 4wboC-4fcuA:
undetectable		 4wboC-4fcuA:
19.77