SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fcy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IIU_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 4fcy TRANSPOSASE
(Escherichia
virus
Mu) 		5 / 11 LEU A 193
LEU A 188
ALA A 222
ALA A 224
LEU A 231
 None
 1.36A 1iiuA-4fcyA:
undetectable		 1iiuA-4fcyA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8E_B_H4BB903_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 4fcy TRANSPOSASE
(Escherichia
virus
Mu) 		3 / 3 ARG A 298
ILE A 266
TRP A 265
 None
 1.21A 1m8eB-4fcyA:
undetectable		 1m8eB-4fcyA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E6T_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 4fcy TRANSPOSASE
(Escherichia
virus
Mu) 		3 / 3 ARG A 298
ILE A 266
TRP A 265
 None
 1.19A 3e6tB-4fcyA:
undetectable		 3e6tB-4fcyA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 4fcy TRANSPOSASE
(Escherichia
virus
Mu) 		3 / 3 ILE A 266
PHE A 318
HIS A 375
 None
 0.69A 3h0aA-4fcyA:
undetectable		 3h0aA-4fcyA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_A_486A3_1
(GLUCOCORTICOID
RECEPTOR)		 4fcy TRANSPOSASE
(Escherichia
virus
Mu) 		5 / 12 LEU A 521
ASN A 520
GLY A 501
VAL A 497
ILE A 554
 None
 0.96A 3h52A-4fcyA:
undetectable		 3h52A-4fcyA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_4
(HIV-1 PROTEASE)		 4fcy TRANSPOSASE
(Escherichia
virus
Mu) 		3 / 3 ARG A 324
VAL A 467
THR A 297
 None
 0.81A 3k4vD-4fcyA:
undetectable		 3k4vD-4fcyA:
10.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 4fcy TRANSPOSASE
(Escherichia
virus
Mu) 		4 / 8 LYS A 197
VAL A 236
TRP A 185
LEU A 188
 None
 0.88A 3v81A-4fcyA:
2.3		 3v81A-4fcyA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PAE_A_NIZA804_1
(CATALASE-PEROXIDASE)		 4fcy TRANSPOSASE
(Escherichia
virus
Mu) 		4 / 6 ASP A 405
LEU A 400
HIS A 273
THR A 289
 None
 1.19A 4paeA-4fcyA:
undetectable		 4paeA-4fcyA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q0B_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE, P66
SUBUNIT)		 4fcy TRANSPOSASE
(Escherichia
virus
Mu) 		4 / 8 LYS A 197
VAL A 236
TRP A 185
LEU A 188
 None
 1.02A 4q0bA-4fcyA:
undetectable		 4q0bA-4fcyA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 4fcy TRANSPOSASE
(Escherichia
virus
Mu) 		4 / 6 PRO A 328
ILE A 266
PHE A 468
ARG A 324
 None
 1.13A 4xe5A-4fcyA:
undetectable		 4xe5A-4fcyA:
19.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4C_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 4fcy TRANSPOSASE
(Escherichia
virus
Mu) 		4 / 6 PRO A 219
LEU A 207
GLU A 208
TYR A 204
 None
 1.29A 4z4cA-4fcyA:
undetectable		 4z4cA-4fcyA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 4fcy TRANSPOSASE
(Escherichia
virus
Mu) 		4 / 6 ASP A 306
ILE A 311
ARG A 315
TYR A 354
 None
 1.04A 5igyA-4fcyA:
undetectable		 5igyA-4fcyA:
22.12