SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fei'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_H_FUAH709_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4fei HEAT SHOCK
PROTEIN-RELATED
PROTEIN
(Deinococcus
radiodurans) 		5 / 12 PHE A 114
LEU A  86
VAL A  88
VAL A 134
ALA A  78
 None
 1.25A 1q23H-4feiA:
undetectable
1q23I-4feiA:
undetectable		 1q23H-4feiA:
18.92
1q23I-4feiA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_B_VD3B700_1
(CYTOCHROME P450 2R1)		 4fei HEAT SHOCK
PROTEIN-RELATED
PROTEIN
(Deinococcus
radiodurans) 		5 / 12 LEU A  79
PHE A 136
VAL A 118
GLY A 123
VAL A  69
 None
 1.07A 3c6gB-4feiA:
undetectable		 3c6gB-4feiA:
14.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_C_RFPC502_1
(RIFAMPIN
MONOOXYGENASE)		 4fei HEAT SHOCK
PROTEIN-RELATED
PROTEIN
(Deinococcus
radiodurans) 		5 / 12 GLY A 130
VAL A  69
PHE A 108
THR A  76
GLY A  75
 None
 1.14A 6brdC-4feiA:
undetectable		 6brdC-4feiA:
25.23