SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ffc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB8_0
(ACTINOMYCIN D)		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		3 / 3 THR A  72
THR A  73
PRO A 423
 None
 0.79A 1a7yB-4ffcA:
undetectable		 1a7yB-4ffcA:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMA_A_SAMA105_0
(PROTEIN (MET
REPRESSOR))		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		4 / 8 GLU A 204
ARG A 208
LEU A 200
GLU A 197
 None
 0.66A 1cmaA-4ffcA:
undetectable
1cmaB-4ffcA:
undetectable		 1cmaA-4ffcA:
13.01
1cmaB-4ffcA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		3 / 3 THR A  73
PRO A 423
THR A  72
 None
 0.86A 1i3wG-4ffcA:
undetectable		 1i3wG-4ffcA:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT7_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		5 / 11 LEU A 112
ALA A  82
VAL A 108
LEU A 298
HIS A  78
 None
 1.39A 1kt7A-4ffcA:
undetectable		 1kt7A-4ffcA:
17.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_B_DVAB8_0
(ACTINOMYCIN X2)		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		3 / 3 THR A  72
THR A  73
PRO A 423
 None
 0.82A 1qfiB-4ffcA:
undetectable		 1qfiB-4ffcA:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R5L_A_VIVA301_0
(PROTEIN
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN))		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		5 / 12 ILE A  63
ILE A 381
ILE A 418
ILE A 435
ILE A 379
 None
 1.13A 1r5lA-4ffcA:
undetectable		 1r5lA-4ffcA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF2_0
(7-AMINO-ACTINOMYCIN
D)		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		3 / 3 THR A  73
PRO A 423
THR A  72
 None
 0.86A 1unjF-4ffcA:
undetectable		 1unjF-4ffcA:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF8_0
(7-AMINO-ACTINOMYCIN
D)		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		3 / 3 THR A  72
THR A  73
PRO A 423
 None
 0.86A 1unjF-4ffcA:
undetectable		 1unjF-4ffcA:
3.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X7P_A_SAMA301_0
(RRNA
METHYLTRANSFERASE)		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		5 / 11 GLY A 235
GLY A 232
ILE A 408
LEU A 420
ALA A 378
 None
 0.93A 1x7pA-4ffcA:
undetectable
1x7pB-4ffcA:
undetectable		 1x7pA-4ffcA:
20.54
1x7pB-4ffcA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		4 / 5 GLY A 412
PRO A 389
VAL A 382
ILE A 381
 EDO  A 502 (-4.0A)
None
None
None
 0.95A 2aoiA-4ffcA:
undetectable		 2aoiA-4ffcA:
12.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CD2_A_FOLA307_0
(DIHYDROFOLATE
REDUCTASE)		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		5 / 12 LEU A 167
ILE A 138
LEU A 222
ILE A 225
THR A 287
 None
 0.97A 2cd2A-4ffcA:
undetectable		 2cd2A-4ffcA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CEO_B_T44B1395_1
(THYROXINE-BINDING
GLOBULIN)		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		5 / 10 ALA A 300
GLN A  88
SER A 299
LEU A 298
ASN A 323
 None
 1.36A 2ceoB-4ffcA:
undetectable		 2ceoB-4ffcA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HW2_A_RFPA1200_1
(RIFAMPIN ADP-RIBOSYL
TRANSFERASE)		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		5 / 12 ALA A 289
GLY A 266
GLY A  66
LEU A 421
LEU A 409
 LLP  A 290 ( 2.7A)
None
None
None
None
 1.04A 2hw2A-4ffcA:
undetectable		 2hw2A-4ffcA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JJP_A_KLNA413_1
(CYTOCHROME P450
113A1)		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		5 / 12 PRO A 229
ALA A 219
LEU A 222
THR A 145
ILE A 259
 None
 1.23A 2jjpA-4ffcA:
undetectable		 2jjpA-4ffcA:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_G_ASDG1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		4 / 7 LEU A 222
ALA A 251
LEU A 247
PHE A 153
 None
 0.88A 2vcvG-4ffcA:
undetectable		 2vcvG-4ffcA:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CL9_A_MTXA602_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE (DHFR-TS))		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		5 / 12 ALA A 437
ILE A  63
SER A  61
LEU A  18
PRO A  19
 None
 1.28A 3cl9A-4ffcA:
undetectable		 3cl9A-4ffcA:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CLB_D_TMQD614_1
(DHFR-TS)		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		5 / 10 VAL A 256
ALA A 141
ILE A 138
ILE A 225
THR A 145
 None
 1.16A 3clbD-4ffcA:
undetectable		 3clbD-4ffcA:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKW_B_DR7B100_2
(PROTEASE)		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		5 / 12 ILE A  54
VAL A  53
GLY A  52
ILE A 426
ALA A  70
 None
None
None
None
LLP  A 290 ( 3.9A)
 0.99A 3ekwB-4ffcA:
undetectable		 3ekwB-4ffcA:
12.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HBB_D_TMQD614_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		5 / 10 VAL A 256
ALA A 141
ILE A 138
ILE A 225
THR A 145
 None
 1.15A 3hbbD-4ffcA:
undetectable		 3hbbD-4ffcA:
23.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LTW_A_HLZA302_1
(ARYLAMINE
N-ACETYLTRANSFERASE
NAT)		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		4 / 6 LEU A 200
GLU A 197
PRO A 198
ARG A 208
 None
 1.49A 3ltwA-4ffcA:
undetectable		 3ltwA-4ffcA:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDV_A_CL6A506_1
(CHOLESTEROL
24-HYDROXYLASE)		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		5 / 9 VAL A 263
LEU A 163
ALA A 133
GLU A 135
THR A 161
 LLP  A 290 ( 4.2A)
None
None
None
None
 1.02A 3mdvA-4ffcA:
undetectable		 3mdvA-4ffcA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QFX_A_CP6A602_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		5 / 12 VAL A 256
ALA A 141
ILE A 138
ILE A 225
THR A 145
 None
 1.07A 3qfxA-4ffcA:
undetectable		 3qfxA-4ffcA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QFX_B_CP6B702_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		5 / 12 VAL A 256
ALA A 141
ILE A 138
ILE A 225
THR A 145
 None
 1.06A 3qfxB-4ffcA:
undetectable		 3qfxB-4ffcA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S79_A_ASDA601_1
(CYTOCHROME P450 19A1)		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		5 / 12 ILE A 225
PHE A 258
ILE A 210
ALA A 209
LEU A 244
 None
 1.28A 3s79A-4ffcA:
undetectable		 3s79A-4ffcA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_A_SALA404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		4 / 7 PRO A  19
TYR A  45
ALA A  27
ARG A  31
 None
 1.00A 3twpA-4ffcA:
undetectable		 3twpA-4ffcA:
26.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_B_SALB404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		4 / 7 PRO A  19
TYR A  45
ALA A  27
ARG A  31
 None
 0.99A 3twpB-4ffcA:
undetectable		 3twpB-4ffcA:
26.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_C_SALC404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		4 / 7 PRO A  19
TYR A  45
ALA A  27
ARG A  31
 None
 1.00A 3twpC-4ffcA:
undetectable		 3twpC-4ffcA:
26.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		4 / 5 ASP A  50
VAL A  53
GLY A  52
TYR A   6
 EDO  A 501 (-2.7A)
None
None
EDO  A 501 (-4.6A)
 1.43A 3w9tA-4ffcA:
undetectable		 3w9tA-4ffcA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		4 / 5 ASP A  50
VAL A  53
GLY A  52
TYR A   6
 EDO  A 501 (-2.7A)
None
None
EDO  A 501 (-4.6A)
 1.44A 3w9tB-4ffcA:
undetectable		 3w9tB-4ffcA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		4 / 5 ASP A  50
VAL A  53
GLY A  52
TYR A   6
 EDO  A 501 (-2.7A)
None
None
EDO  A 501 (-4.6A)
 1.44A 3w9tC-4ffcA:
undetectable		 3w9tC-4ffcA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		4 / 5 ASP A  50
VAL A  53
GLY A  52
TYR A   6
 EDO  A 501 (-2.7A)
None
None
EDO  A 501 (-4.6A)
 1.43A 3w9tD-4ffcA:
undetectable		 3w9tD-4ffcA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		4 / 5 ASP A  50
VAL A  53
GLY A  52
TYR A   6
 EDO  A 501 (-2.7A)
None
None
EDO  A 501 (-4.6A)
 1.44A 3w9tE-4ffcA:
undetectable		 3w9tE-4ffcA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		4 / 5 ASP A  50
VAL A  53
GLY A  52
TYR A   6
 EDO  A 501 (-2.7A)
None
None
EDO  A 501 (-4.6A)
 1.44A 3w9tF-4ffcA:
undetectable		 3w9tF-4ffcA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		4 / 5 ASP A  50
VAL A  53
GLY A  52
TYR A   6
 EDO  A 501 (-2.7A)
None
None
EDO  A 501 (-4.6A)
 1.44A 3w9tG-4ffcA:
undetectable		 3w9tG-4ffcA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		5 / 11 GLY A 130
VAL A 134
GLU A 135
SER A 129
VAL A 263
 LLP  A 290 ( 3.4A)
None
None
LLP  A 290 ( 3.9A)
LLP  A 290 ( 4.2A)
 1.27A 4danA-4ffcA:
undetectable		 4danA-4ffcA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_B_MRVB1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		4 / 5 TYR A 157
THR A 326
LEU A 298
THR A 287
 LLP  A 290 ( 4.8A)
None
None
None
 1.43A 4mbsB-4ffcA:
undetectable		 4mbsB-4ffcA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_C_AERC601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		4 / 6 TYR A  45
LEU A 407
VAL A  71
ALA A  70
 None
None
LLP  A 290 ( 3.7A)
LLP  A 290 ( 3.9A)
 0.87A 4nkvC-4ffcA:
undetectable		 4nkvC-4ffcA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD4_C_AOQC4003_1
(CYTOCHROME B)		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		5 / 12 PHE A  62
ILE A  14
PRO A  43
LEU A 402
ILE A 441
 None
 1.02A 4pd4C-4ffcA:
undetectable		 4pd4C-4ffcA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RDX_A_HISA502_0
(HISTIDINE--TRNA
LIGASE)		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		4 / 7 GLU A 228
ARG A 371
GLY A 235
GLY A 232
 LLP  A 290 ( 3.7A)
None
None
None
 0.87A 4rdxA-4ffcA:
undetectable		 4rdxA-4ffcA:
25.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MVM_A_PFLA511_1
(PROTON-GATED ION
CHANNEL)		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		4 / 8 ILE A 225
ALA A 251
ALA A 206
ILE A 210
 None
 0.67A 5mvmA-4ffcA:
undetectable
5mvmB-4ffcA:
undetectable		 5mvmA-4ffcA:
10.71
5mvmB-4ffcA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_A_BEZA507_0
(BETA-LACTAMASE VIM-2)		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		3 / 3 THR A 319
HIS A  94
ASN A 323
 None
 0.71A 5n4tA-4ffcA:
undetectable		 5n4tA-4ffcA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_0
(CYTOCHROME P450 1A1)		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		5 / 12 ILE A 349
LEU A 342
GLY A 427
ILE A 435
LEU A  65
 None
 1.13A 6dwnC-4ffcA:
undetectable		 6dwnC-4ffcA:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HQB_A_PQNA2001_0
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1
PHOTOSYSTEM I
REACTION CENTER
SUBUNIT IX)		 4ffc 4-AMINOBUTYRATE
AMINOTRANSFERASE
(GABT)
(Mycobacteroides
abscessus) 		5 / 10 GLY A 321
ALA A 125
LEU A 316
GLY A 317
LEU A 222
 None
 1.25A 6hqbA-4ffcA:
undetectable
6hqbJ-4ffcA:
undetectable		 6hqbA-4ffcA:
9.58
6hqbJ-4ffcA:
7.28