SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fff'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_GLYB2292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		4 / 8 PHE A 477
SER A 486
HIS A  44
SER A 473
 None
 1.20A 1eqbA-4fffA:
undetectable
1eqbB-4fffA:
undetectable		 1eqbA-4fffA:
20.83
1eqbB-4fffA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_GLYD4292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		4 / 8 PHE A 477
SER A 486
HIS A  44
SER A 473
 None
 1.21A 1eqbC-4fffA:
undetectable
1eqbD-4fffA:
undetectable		 1eqbC-4fffA:
20.83
1eqbD-4fffA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA8_0
(GRAMICIDIN A)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		3 / 4 VAL A 484
TRP A 290
TRP A 297
 None
 0.62A 1gmkA-4fffA:
undetectable
1gmkB-4fffA:
undetectable		 1gmkA-4fffA:
4.67
1gmkB-4fffA:
4.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC8_0
(GRAMICIDIN A)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		3 / 4 VAL A 484
TRP A 290
TRP A 297
 None
 0.86A 1gmkC-4fffA:
undetectable
1gmkD-4fffA:
undetectable		 1gmkC-4fffA:
4.67
1gmkD-4fffA:
4.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXW_B_RITB301_1
(HIV-1 PROTEASE)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		5 / 9 ASP A 292
GLY A 294
ASP A 296
ILE A 467
PRO A 363
 None
 0.89A 1hxwA-4fffA:
undetectable		 1hxwA-4fffA:
11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HZ4_A_BEZA784_0
(MALT REGULATORY
PROTEIN)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		4 / 6 TRP A 219
LEU A 146
LEU A 159
PRO A 160
 None
 1.32A 1hz4A-4fffA:
undetectable		 1hz4A-4fffA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD508_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		4 / 6 PHE A 210
ASN A 224
ILE A 202
GLY A 203
 None
 1.12A 1oniD-4fffA:
undetectable
1oniF-4fffA:
undetectable		 1oniD-4fffA:
14.10
1oniF-4fffA:
14.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG1_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		3 / 3 TRP A 108
VAL A 107
PRO A 106
 None
 0.86A 1rg1A-4fffA:
undetectable		 1rg1A-4fffA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RH0_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		3 / 3 TRP A 108
VAL A 107
PRO A 106
 None
 0.86A 1rh0A-4fffA:
undetectable		 1rh0A-4fffA:
21.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		4 / 6 ARG A 139
ASP A 226
ASN A 224
GLU A 182
 None
 1.24A 1rjdA-4fffA:
undetectable		 1rjdA-4fffA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		4 / 6 ARG A 139
ASP A 226
ASN A 224
GLU A 182
 None
 1.28A 1rjdB-4fffA:
undetectable		 1rjdB-4fffA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		4 / 6 ARG A 139
ASP A 226
ASN A 224
GLU A 182
 None
 1.27A 1rjdC-4fffA:
undetectable		 1rjdC-4fffA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UAK_A_SAMA301_0
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		5 / 12 GLY A 392
SER A 412
ILE A 411
VAL A 387
LEU A 388
 None
 0.80A 1uakA-4fffA:
undetectable		 1uakA-4fffA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AQU_B_DR7B300_1
(HIV-1 PROTEASE)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		5 / 10 ASP A 292
GLY A 294
ASP A 296
ILE A 467
PRO A 363
 None
 0.94A 2aquA-4fffA:
undetectable		 2aquA-4fffA:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FXE_A_DR7A102_2
(POL PROTEIN)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		5 / 11 ASP A 292
GLY A 294
ASP A 296
ILE A 467
PRO A 363
 None
 0.88A 2fxeB-4fffA:
undetectable		 2fxeB-4fffA:
11.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA702_0
(FERROCHELATASE)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		4 / 7 ARG A 313
LEU A 347
PRO A 266
MET A 258
 None
 1.01A 2hrcA-4fffA:
undetectable		 2hrcA-4fffA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEO_A_017A402_1
(PROTEASE)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		5 / 12 ASP A 292
GLY A 294
ASP A 296
ILE A 467
PRO A 363
 None
 0.92A 2ieoA-4fffA:
undetectable		 2ieoA-4fffA:
13.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMY_A_ROCA401_1
(PROTEASE)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		5 / 12 ASP A 292
GLY A 294
ASP A 296
ILE A 467
PRO A 363
 None
 0.86A 2nmyA-4fffA:
undetectable		 2nmyA-4fffA:
12.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y00_B_Y00B601_2
(BETA-1 ADRENERGIC
RECEPTOR)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		3 / 3 VAL A 329
ASN A 320
TRP A 322
 None
 0.99A 2y00B-4fffA:
undetectable		 2y00B-4fffA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DFR_A_MTXA164_1
(DIHYDROFOLATE
REDUCTASE)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		5 / 12 LEU A  67
HIS A  83
SER A 342
LEU A  52
ALA A 299
 None
 1.11A 3dfrA-4fffA:
undetectable		 3dfrA-4fffA:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKY_A_DR7A100_1
(PROTEASE)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		5 / 10 ASP A 292
GLY A 294
ASP A 296
ILE A 467
PRO A 363
 None
 0.95A 3ekyA-4fffA:
undetectable		 3ekyA-4fffA:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_1
(PROTEASE)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		4 / 8 ASP A 292
GLY A 294
ASP A 296
PRO A 363
 None
 0.57A 3el0A-4fffA:
undetectable		 3el0A-4fffA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL9_A_DR7A100_2
(PROTEASE)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		5 / 10 ASP A 292
GLY A 294
ASP A 296
ILE A 467
PRO A 363
 None
 0.94A 3el9B-4fffA:
undetectable		 3el9B-4fffA:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB2_A_IBPA3960_1
(LACTOTRANSFERRIN)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		4 / 4 GLY A 518
VAL A  42
GLY A 392
THR A 496
 None
 0.79A 3ib2A-4fffA:
undetectable		 3ib2A-4fffA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		5 / 12 THR A 362
SER A 342
ASP A 470
ILE A 517
LEU A 367
 None
 1.31A 3iv6C-4fffA:
undetectable		 3iv6C-4fffA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_4
(HIV-1 PROTEASE)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		3 / 3 ARG A 461
VAL A 382
THR A 502
 None
 0.59A 3k4vD-4fffA:
undetectable		 3k4vD-4fffA:
12.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_D_VIBD223_1
(THIAMINE
PYROPHOSPHOKINASE)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		4 / 8 ASP A 495
HIS A  44
LEU A 441
SER A 473
 None
 1.02A 3lm8B-4fffA:
2.4
3lm8D-4fffA:
2.4		 3lm8B-4fffA:
18.13
3lm8D-4fffA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LOQ_A_ACTA278_0
(UNIVERSAL STRESS
PROTEIN)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		3 / 3 SER A 450
GLY A 437
SER A 445
 None
 0.53A 3loqA-4fffA:
undetectable		 3loqA-4fffA:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_C_ACTC800_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		3 / 3 ASP A 246
ARG A 351
ALA A 245
 None
 0.76A 3mbgC-4fffA:
undetectable		 3mbgC-4fffA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_C_RBVC601_1
(RNA POLYMERASE)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		5 / 11 LEU A 359
ASP A 246
THR A 311
GLY A 248
ASP A 247
 None
 1.31A 3sfuC-4fffA:
undetectable		 3sfuC-4fffA:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_A_T1CA404_1
(TETX2 PROTEIN)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		5 / 12 THR A 420
ARG A 421
GLY A 497
GLY A 437
GLN A 488
 None
 1.13A 3v3oA-4fffA:
undetectable		 3v3oA-4fffA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FFW_B_715B801_2
(DIPEPTIDYL PEPTIDASE
4)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		3 / 3 ARG A  57
TYR A 298
ASN A 341
 None
 0.81A 4ffwB-4fffA:
6.7		 4ffwB-4fffA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G1B_C_ECNC403_1
(FLAVOHEMOGLOBIN)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		5 / 9 ILE A 235
TYR A 269
VAL A 201
VAL A 253
LEU A 254
 None
 1.25A 4g1bC-4fffA:
undetectable		 4g1bC-4fffA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M2X_A_TMQA202_2
(DIHYDROFOLATE
REDUCTASE)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		3 / 3 TRP A 272
GLN A 352
THR A 273
 None
 0.85A 4m2xA-4fffA:
undetectable		 4m2xA-4fffA:
18.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_A_377A402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		5 / 9 ALA A 315
SER A 361
SER A 486
ALA A 317
SER A 342
 None
 1.15A 4twdA-4fffA:
undetectable
4twdB-4fffA:
undetectable
4twdC-4fffA:
undetectable
4twdD-4fffA:
undetectable
4twdE-4fffA:
undetectable		 4twdA-4fffA:
21.26
4twdB-4fffA:
21.26
4twdC-4fffA:
21.26
4twdD-4fffA:
21.26
4twdE-4fffA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_A_377A402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		5 / 9 ALA A 317
SER A 342
ALA A 315
SER A 361
SER A 486
 None
 1.10A 4twdA-4fffA:
undetectable
4twdB-4fffA:
undetectable
4twdC-4fffA:
undetectable
4twdD-4fffA:
undetectable
4twdE-4fffA:
undetectable		 4twdA-4fffA:
21.26
4twdB-4fffA:
21.26
4twdC-4fffA:
21.26
4twdD-4fffA:
21.26
4twdE-4fffA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_A_377A402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		5 / 9 SER A 486
ALA A 317
SER A 342
ALA A 315
SER A 361
 None
 0.99A 4twdA-4fffA:
undetectable
4twdB-4fffA:
undetectable
4twdC-4fffA:
undetectable
4twdD-4fffA:
undetectable
4twdE-4fffA:
undetectable		 4twdA-4fffA:
21.26
4twdB-4fffA:
21.26
4twdC-4fffA:
21.26
4twdD-4fffA:
21.26
4twdE-4fffA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_A_ACTA404_0
(PROTON-GATED ION
CHANNEL)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		4 / 4 LEU A 221
ILE A 164
ARG A 204
TYR A 211
 None
 1.40A 4zzbA-4fffA:
undetectable		 4zzbA-4fffA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_A_ACTA406_0
(PROTON-GATED ION
CHANNEL)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		4 / 4 LEU A 221
ILE A 164
ARG A 204
TYR A 211
 None
 1.31A 4zzcA-4fffA:
undetectable		 4zzcA-4fffA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_B_ACTB406_0
(PROTON-GATED ION
CHANNEL)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		4 / 4 LEU A 221
ILE A 164
ARG A 204
TYR A 211
 None
 1.30A 4zzcB-4fffA:
undetectable		 4zzcB-4fffA:
23.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_G_EVPG2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		4 / 6 SER A 334
GLY A 494
ASP A 495
ARG A 421
 None
 0.88A 5cdnA-4fffA:
undetectable
5cdnB-4fffA:
undetectable		 5cdnA-4fffA:
22.28
5cdnB-4fffA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDP_H_EVPH2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		4 / 6 SER A 334
GLY A 494
ASP A 495
ARG A 421
 None
 1.00A 5cdpA-4fffA:
undetectable
5cdpB-4fffA:
undetectable		 5cdpA-4fffA:
22.78
5cdpB-4fffA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_B_SAMB501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		5 / 9 ARG A 345
LEU A 465
ILE A 467
LEU A 432
LEU A 485
 None
 0.96A 5o96A-4fffA:
undetectable
5o96B-4fffA:
undetectable		 5o96A-4fffA:
20.29
5o96B-4fffA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9A_A_AR3A201_1
(PEPTIDYL-TRNA
HYDROLASE)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		4 / 6 ALA A  41
GLN A 472
GLN A 488
ASP A 296
 None
 1.40A 5y9aA-4fffA:
undetectable		 5y9aA-4fffA:
19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZHM_B_SAMB301_1
(TRNA
(GUANINE-N(1)-)-METH
YLTRANSFERASE)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		5 / 12 GLY A 392
SER A 412
ILE A 411
VAL A 387
LEU A 388
 None
 0.89A 5zhmB-4fffA:
undetectable		 5zhmB-4fffA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_D_GLYD713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		3 / 3 ARG A  57
HIS A 190
ARG A 313
 None
 0.91A 6dwdD-4fffA:
undetectable		 6dwdD-4fffA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EU9_B_REAB601_1
(RETINOIC ACID
RECEPTOR)		 4fff LEVAN
FRUCTOTRANSFERASE
(Paenarthrobacter
ureafaciens) 		5 / 10 VAL A 474
LEU A 432
GLY A 414
GLY A 426
VAL A 434
 None
 0.98A 6eu9B-4fffA:
undetectable		 6eu9B-4fffA:
12.38