SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ffu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O1C_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 4ffu OXIDASE
(Sinorhizobium
meliloti) 		5 / 10 ILE A   6
ILE A 106
LEU A 142
SER A  74
HIS A 140
 None
 1.23A 3o1cA-4ffuA:
undetectable		 3o1cA-4ffuA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O1X_A_ADNA1450_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 4ffu OXIDASE
(Sinorhizobium
meliloti) 		5 / 10 ILE A   6
ILE A 106
LEU A 142
SER A  74
HIS A 140
 None
 1.23A 3o1xA-4ffuA:
undetectable		 3o1xA-4ffuA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QGZ_A_ADNA127_1
(HISTIDINE TRIAD
NUCLEOTIDE-BINDING
PROTEIN 1)		 4ffu OXIDASE
(Sinorhizobium
meliloti) 		5 / 10 ILE A   6
ILE A 106
LEU A 142
SER A  74
HIS A 140
 None
 1.17A 3qgzA-4ffuA:
undetectable		 3qgzA-4ffuA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_B_SAMB300_0
(PUTATIVE
METHYLTRANSFERASE)		 4ffu OXIDASE
(Sinorhizobium
meliloti) 		5 / 12 ARG A  57
GLN A  56
GLY A  97
ASP A  98
GLU A  26
 None
 1.33A 3t7sB-4ffuA:
undetectable		 3t7sB-4ffuA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_D_SAMD300_0
(PUTATIVE
METHYLTRANSFERASE)		 4ffu OXIDASE
(Sinorhizobium
meliloti) 		5 / 12 ARG A  57
GLN A  56
GLY A  97
ASP A  98
GLU A  26
 None
 1.34A 3t7sD-4ffuA:
undetectable		 3t7sD-4ffuA:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG306_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4ffu OXIDASE
(Sinorhizobium
meliloti) 		3 / 3 ARG A  89
ARG A 124
ASP A  86
 None
 0.88A 3wipG-4ffuA:
undetectable
3wipH-4ffuA:
undetectable		 3wipG-4ffuA:
18.61
3wipH-4ffuA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_C_ZPCC1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4ffu OXIDASE
(Sinorhizobium
meliloti) 		5 / 12 VAL A  79
ASN A  77
GLU A   9
GLU A 123
ILE A 106
 None
 1.23A 4a97B-4ffuA:
undetectable
4a97C-4ffuA:
undetectable		 4a97B-4ffuA:
19.68
4a97C-4ffuA:
19.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_B_AERB601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 4ffu OXIDASE
(Sinorhizobium
meliloti) 		4 / 5 ARG A 120
ASP A  86
GLU A 123
VAL A  69
 None
 1.21A 4nkvB-4ffuA:
undetectable		 4nkvB-4ffuA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 4ffu OXIDASE
(Sinorhizobium
meliloti) 		4 / 5 ARG A 120
ASP A  86
GLU A 123
VAL A  69
 None
 1.23A 4nkxC-4ffuA:
undetectable		 4nkxC-4ffuA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_D_STRD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 4ffu OXIDASE
(Sinorhizobium
meliloti) 		4 / 5 ARG A 120
ASP A  86
GLU A 123
VAL A  69
 None
 1.25A 4nkxD-4ffuA:
undetectable		 4nkxD-4ffuA:
17.85