SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fgo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2887_1
(AMINOMETHYLTRANSFERA
SE)		 4fgo PERIPLASMIC PROTEIN
(Legionella
pneumophila) 		3 / 3 ASP A 136
GLU A 128
ARG A  78
 CA  A 301 (-2.6A)
None
None
 0.83A 1wopA-4fgoA:
undetectable		 1wopA-4fgoA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3O_A_DLUA399_1
(PFV INTEGRASE)		 4fgo PERIPLASMIC PROTEIN
(Legionella
pneumophila) 		4 / 7 ASP A 136
ASP A 139
GLU A 138
ARG A 242
 CA  A 301 (-2.6A)
CA  A 301 (-2.5A)
CA  A 301 (-4.2A)
None
 1.16A 3s3oA-4fgoA:
undetectable		 3s3oA-4fgoA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_A_ILEA601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4fgo PERIPLASMIC PROTEIN
(Legionella
pneumophila) 		4 / 6 ALA A 163
VAL A 207
TYR A 208
HIS A 172
 None
 0.96A 5eckA-4fgoA:
undetectable		 5eckA-4fgoA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_D_ILED601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4fgo PERIPLASMIC PROTEIN
(Legionella
pneumophila) 		4 / 6 ALA A 163
VAL A 207
TYR A 208
HIS A 172
 None
 0.88A 5eckD-4fgoA:
undetectable		 5eckD-4fgoA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECL_A_ILEA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4fgo PERIPLASMIC PROTEIN
(Legionella
pneumophila) 		4 / 6 ALA A 163
VAL A 207
TYR A 208
HIS A 172
 None
 0.99A 5eclA-4fgoA:
undetectable		 5eclA-4fgoA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4fgo PERIPLASMIC PROTEIN
(Legionella
pneumophila) 		5 / 7 ALA A 163
VAL A 207
TYR A 208
GLU A 138
HIS A 172
 None
None
None
CA  A 301 (-4.2A)
None
 0.97A 5ecmD-4fgoA:
0.5		 5ecmD-4fgoA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECO_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 4fgo PERIPLASMIC PROTEIN
(Legionella
pneumophila) 		5 / 7 ALA A 163
VAL A 207
TYR A 208
GLU A 138
HIS A 172
 None
None
None
CA  A 301 (-4.2A)
None
 1.11A 5ecoD-4fgoA:
undetectable		 5ecoD-4fgoA:
15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DCH_A_ACTA401_0
(SCOE PROTEIN)		 4fgo PERIPLASMIC PROTEIN
(Legionella
pneumophila) 		4 / 5 THR A 167
ASP A 189
HIS A 172
ARG A 201
 None
 1.42A 6dchA-4fgoA:
undetectable		 6dchA-4fgoA:
23.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DCH_A_ACTA401_0
(SCOE PROTEIN)		 4fgo PERIPLASMIC PROTEIN
(Legionella
pneumophila) 		4 / 5 THR A 167
HIS A 172
ASP A 189
ARG A 201
 None
 1.49A 6dchA-4fgoA:
undetectable		 6dchA-4fgoA:
23.03