SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fgs'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4fgs PROBABLE
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		6 / 12 TYR A 151
ILE A  19
GLY A 137
ALA A 156
SER A 154
GLY A 182
 None
 1.16A 1kiaA-4fgsA:
8.2		 1kiaA-4fgsA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4fgs PROBABLE
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		5 / 12 TYR A 151
ILE A  19
GLY A 137
ALA A 156
GLY A 182
 None
 1.04A 1kiaB-4fgsA:
8.4		 1kiaB-4fgsA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4fgs PROBABLE
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		5 / 12 TYR A 151
ILE A  19
GLY A 137
ALA A 156
GLY A 182
 None
 1.04A 1kiaC-4fgsA:
8.1		 1kiaC-4fgsA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4fgs PROBABLE
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		5 / 12 TYR A 151
ILE A  19
GLY A 137
ALA A 156
SER A 154
 None
 1.18A 1nbhA-4fgsA:
8.1		 1nbhA-4fgsA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4fgs PROBABLE
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		6 / 12 TYR A 151
ILE A  19
GLY A 137
ALA A 156
SER A 154
GLY A 182
 None
 1.19A 1nbhB-4fgsA:
7.8		 1nbhB-4fgsA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4fgs PROBABLE
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		5 / 12 TYR A 151
ILE A  19
GLY A 137
ALA A 156
SER A 154
 None
 1.18A 1nbhC-4fgsA:
7.5		 1nbhC-4fgsA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4fgs PROBABLE
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		5 / 12 TYR A 151
ILE A  19
GLY A 137
ALA A 156
SER A 154
 None
 1.19A 1nbhD-4fgsA:
7.8		 1nbhD-4fgsA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4fgs PROBABLE
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		6 / 12 TYR A 151
ILE A  19
GLY A 137
ALA A 156
SER A 154
GLY A 182
 None
 1.20A 1nbiA-4fgsA:
7.9		 1nbiA-4fgsA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_B_SAMB1293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4fgs PROBABLE
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		6 / 12 TYR A 151
ILE A  19
GLY A 137
ALA A 156
SER A 154
GLY A 182
 None
 1.19A 1nbiB-4fgsA:
8.0		 1nbiB-4fgsA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_C_SAMC2293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4fgs PROBABLE
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		6 / 12 TYR A 151
GLY A 137
THR A 136
ALA A 156
SER A 154
GLY A 182
 None
 1.20A 1nbiC-4fgsA:
7.7		 1nbiC-4fgsA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBI_D_SAMD3293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4fgs PROBABLE
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		6 / 12 TYR A 151
GLY A 137
THR A 136
ALA A 156
SER A 154
GLY A 182
 None
 1.19A 1nbiD-4fgsA:
7.5		 1nbiD-4fgsA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_0
(MODIFICATION
METHYLASE RSRI)		 4fgs PROBABLE
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		5 / 12 PRO A 181
GLY A  18
SER A  17
ALA A 223
ALA A  23
 None
 1.27A 1nw5A-4fgsA:
3.0		 1nw5A-4fgsA:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_B_SAMB302_0
(HEMK PROTEIN)		 4fgs PROBABLE
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		5 / 12 THR A 184
GLY A 137
ILE A  19
SER A 154
ALA A 140
 None
 0.99A 1sg9B-4fgsA:
7.1		 1sg9B-4fgsA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T87_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 4fgs PROBABLE
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		4 / 7 TYR A  72
THR A 119
LEU A  85
VAL A  11
 None
 1.07A 1t87A-4fgsA:
undetectable		 1t87A-4fgsA:
21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZUC_B_T98B202_1
(PROGESTERONE
RECEPTOR)		 4fgs PROBABLE
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		5 / 12 LEU A  65
LEU A  68
LEU A  71
LEU A  85
LEU A 117
 None
 1.01A 1zucB-4fgsA:
undetectable		 1zucB-4fgsA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_B_SAMB602_0
(HYPOTHETICAL PROTEIN)		 4fgs PROBABLE
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		5 / 12 GLY A 137
SER A 138
GLY A 141
VAL A 134
ILE A 176
 None
 1.16A 2b25B-4fgsA:
6.8		 2b25B-4fgsA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZUI_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 4fgs PROBABLE
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		4 / 6 TYR A  72
THR A 119
LEU A  85
VAL A  11
 None
 1.08A 2zuiA-4fgsA:
undetectable		 2zuiA-4fgsA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CWK_A_REAA300_1
(CELLULAR RETINOIC
ACID-BINDING PROTEIN
2)		 4fgs PROBABLE
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		5 / 12 PHE A  86
LEU A  21
ALA A  23
ALA A 226
VAL A 244
 None
 1.19A 3cwkA-4fgsA:
undetectable		 3cwkA-4fgsA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		 4fgs PROBABLE
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		5 / 12 LEU A  65
LEU A  68
LEU A  71
LEU A  85
LEU A 117
 None
 1.03A 3d90B-4fgsA:
undetectable		 3d90B-4fgsA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EBZ_B_017B201_2
(PROTEASE)		 4fgs PROBABLE
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		5 / 11 GLY A  14
ALA A  15
ILE A  51
VAL A  34
ILE A  58
 None
 1.03A 3ebzB-4fgsA:
undetectable		 3ebzB-4fgsA:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB1_A_SAMA1101_0
(STRUCTURAL PROTEIN
VP3)		 4fgs PROBABLE
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		5 / 12 ARG A  26
ALA A 226
ALA A  29
ILE A  19
ALA A 219
 None
 1.09A 3jb1A-4fgsA:
2.4		 3jb1A-4fgsA:
13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S43_A_478A401_2
(PROTEASE)		 4fgs PROBABLE
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		5 / 10 GLY A  14
ALA A  15
ILE A  51
VAL A  34
ILE A  58
 None
 0.91A 3s43B-4fgsA:
undetectable		 3s43B-4fgsA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4fgs PROBABLE
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		4 / 7 TYR A  72
THR A 119
LEU A  85
VAL A  11
 None
 1.02A 3wrhA-4fgsA:
undetectable		 3wrhA-4fgsA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4fgs PROBABLE
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		4 / 7 TYR A  72
THR A 119
LEU A  85
VAL A  11
 None
 1.05A 3wrjA-4fgsA:
undetectable		 3wrjA-4fgsA:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G77_A_TLFA711_0
(LACTOTRANSFERRIN)		 4fgs PROBABLE
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		4 / 7 ILE A  51
ALA A  55
VAL A  56
ALA A  15
 None
 0.82A 4g77A-4fgsA:
undetectable		 4g77A-4fgsA:
20.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4G_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 4fgs PROBABLE
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		4 / 7 TYR A  72
THR A 119
LEU A  85
VAL A  11
 None
 1.04A 4l4gA-4fgsA:
undetectable		 4l4gA-4fgsA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OR0_A_NPSA602_1
(SERUM ALBUMIN)		 4fgs PROBABLE
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		5 / 9 PHE A 228
ALA A 225
ALA A 223
SER A 234
LEU A 229
 None
 1.35A 4or0A-4fgsA:
undetectable		 4or0A-4fgsA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T8H_B_478B401_1
(PROTEASE)		 4fgs PROBABLE
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		5 / 12 GLY A  14
ALA A  15
ILE A  51
VAL A  34
ILE A  58
 None
 0.91A 5t8hA-4fgsA:
undetectable		 5t8hA-4fgsA:
16.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCE_A_RITA602_1
(CYTOCHROME P450 3A4)		 4fgs PROBABLE
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		5 / 12 ILE A 176
ILE A 174
ALA A 128
ILE A   9
ALA A  10
 None
 1.11A 5vceA-4fgsA:
undetectable		 5vceA-4fgsA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 4fgs PROBABLE
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		5 / 12 GLY A  18
ALA A  22
PHE A  86
ASN A  88
VAL A 134
 None
 1.17A 6bqgA-4fgsA:
undetectable		 6bqgA-4fgsA:
15.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRX_A_H8GA1201_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 4fgs PROBABLE
DEHYDROGENASE
PROTEIN
(Rhizobium
etli) 		5 / 12 VAL A 222
ALA A  22
PHE A  86
ASN A  88
VAL A 134
 None
 1.02A 6drxA-4fgsA:
undetectable		 6drxA-4fgsA:
21.39