SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fi9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC2_0
(ACTINOMYCIN D)		 4fi9 SUN
DOMAIN-CONTAINING
PROTEIN 2
(Homo
sapiens) 		3 / 3 THR A 696
PRO A 643
PRO A 607
 None
 0.71A 2d55C-4fi9A:
undetectable		 2d55C-4fi9A:
7.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC8_0
(ACTINOMYCIN D)		 4fi9 SUN
DOMAIN-CONTAINING
PROTEIN 2
(Homo
sapiens) 		3 / 3 PRO A 607
THR A 696
PRO A 643
 None
 0.79A 2d55C-4fi9A:
undetectable		 2d55C-4fi9A:
7.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fi9 SUN
DOMAIN-CONTAINING
PROTEIN 2
(Homo
sapiens) 		4 / 8 ILE A 648
PHE A 679
ARG A 710
LEU A 615
 None
 0.85A 2eijN-4fi9A:
undetectable
2eijW-4fi9A:
undetectable		 2eijN-4fi9A:
17.12
2eijW-4fi9A:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fi9 SUN
DOMAIN-CONTAINING
PROTEIN 2
(Homo
sapiens) 		4 / 8 ILE A 648
PHE A 679
ARG A 710
LEU A 615
 None
 0.86A 2eikN-4fi9A:
undetectable
2eikW-4fi9A:
undetectable		 2eikN-4fi9A:
17.12
2eikW-4fi9A:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fi9 SUN
DOMAIN-CONTAINING
PROTEIN 2
(Homo
sapiens) 		4 / 8 ILE A 648
PHE A 679
ARG A 710
LEU A 615
 None
 0.86A 2eilN-4fi9A:
undetectable
2eilW-4fi9A:
undetectable		 2eilN-4fi9A:
17.12
2eilW-4fi9A:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fi9 SUN
DOMAIN-CONTAINING
PROTEIN 2
(Homo
sapiens) 		4 / 7 ILE A 648
LEU A 662
PHE A 679
ARG A 710
 None
 0.95A 3ag2N-4fi9A:
undetectable
3ag2W-4fi9A:
undetectable		 3ag2N-4fi9A:
17.12
3ag2W-4fi9A:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fi9 SUN
DOMAIN-CONTAINING
PROTEIN 2
(Homo
sapiens) 		4 / 7 ILE A 648
LEU A 662
PHE A 679
ARG A 710
 None
 0.99A 3ag4N-4fi9A:
undetectable
3ag4W-4fi9A:
undetectable		 3ag4N-4fi9A:
17.12
3ag4W-4fi9A:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 4fi9 SUN
DOMAIN-CONTAINING
PROTEIN 2
(Homo
sapiens) 		4 / 8 ILE A 648
PHE A 679
ARG A 710
LEU A 615
 None
 0.84A 3asnN-4fi9A:
undetectable
3asnW-4fi9A:
undetectable		 3asnN-4fi9A:
17.12
3asnW-4fi9A:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA153_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4fi9 SUN
DOMAIN-CONTAINING
PROTEIN 2
(Homo
sapiens) 		4 / 5 ILE A 544
THR A 622
PHE A 679
PHE A 665
 None
 1.20A 3em0A-4fi9A:
undetectable		 3em0A-4fi9A:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G24_A_ACAA1004_1
(PENTATRICOPEPTIDE
REPEAT-CONTAINING
PROTEIN AT2G32230,
MITOCHONDRIAL)		 4fi9 SUN
DOMAIN-CONTAINING
PROTEIN 2
(Homo
sapiens) 		4 / 6 ALA A 556
LEU A 615
VAL A 689
GLU A 691
 None
 1.02A 4g24A-4fi9A:
undetectable		 4g24A-4fi9A:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_2
(ASPARTYL PROTEASE)		 4fi9 SUN
DOMAIN-CONTAINING
PROTEIN 2
(Homo
sapiens) 		5 / 12 LEU A 592
ALA A 611
ILE A 706
ILE A 694
ILE A 591
 None
 0.94A 4q1yB-4fi9A:
undetectable		 4q1yB-4fi9A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A1R_A_STRA600_1
(CYTOCHROME P450 3A4)		 4fi9 SUN
DOMAIN-CONTAINING
PROTEIN 2
(Homo
sapiens) 		4 / 5 PHE A 679
PHE A 677
PHE A 665
VAL A 624
 None
 1.20A 5a1rA-4fi9A:
undetectable		 5a1rA-4fi9A:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4fi9 SUN
DOMAIN-CONTAINING
PROTEIN 2
(Homo
sapiens) 		4 / 6 ILE A 648
LEU A 662
PHE A 679
ARG A 710
 None
 0.89A 5b1aN-4fi9A:
undetectable
5b1aW-4fi9A:
undetectable		 5b1aN-4fi9A:
17.12
5b1aW-4fi9A:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4fi9 SUN
DOMAIN-CONTAINING
PROTEIN 2
(Homo
sapiens) 		4 / 7 ILE A 648
PHE A 679
ARG A 710
LEU A 615
 None
 0.75A 5b1bN-4fi9A:
undetectable
5b1bW-4fi9A:
undetectable		 5b1bN-4fi9A:
17.12
5b1bW-4fi9A:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4fi9 SUN
DOMAIN-CONTAINING
PROTEIN 2
(Homo
sapiens) 		4 / 7 ILE A 648
PHE A 679
ARG A 710
LEU A 615
 None
 0.86A 5b3sN-4fi9A:
undetectable
5b3sW-4fi9A:
undetectable		 5b3sN-4fi9A:
17.12
5b3sW-4fi9A:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 4fi9 SUN
DOMAIN-CONTAINING
PROTEIN 2
(Homo
sapiens) 		4 / 8 LEU A 626
VAL A 624
VAL A 613
VAL A 690
 None
 1.08A 6cp4A-4fi9A:
undetectable		 6cp4A-4fi9A:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4fi9 SUN
DOMAIN-CONTAINING
PROTEIN 2
(Homo
sapiens) 		4 / 5 ILE A 648
LEU A 662
ARG A 710
LEU A 615
 None
 0.90A 6nmpN-4fi9A:
undetectable
6nmpW-4fi9A:
undetectable		 6nmpN-4fi9A:
17.12
6nmpW-4fi9A:
16.15