SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fib'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_A_DVAA6_0
(GRAMICIDIN C)		 4fib UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		3 / 3 ALA A 172
VAL A 115
TRP A 132
 None
 0.80A 1nt6A-4fibA:
undetectable		 1nt6A-4fibA:
8.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT6_B_DVAB6_0
(GRAMICIDIN C)		 4fib UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		3 / 3 ALA A 172
VAL A 115
TRP A 132
 None
 0.80A 1nt6B-4fibA:
undetectable		 1nt6B-4fibA:
8.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OQ5_A_CELA701_2
(CARBONIC ANHYDRASE
II)		 4fib UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		4 / 4 HIS A 194
VAL A 180
THR A  92
LEU A 203
 None
 1.42A 1oq5A-4fibA:
undetectable		 1oq5A-4fibA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_C_CHDC3525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 4fib UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 170
TYR A 114
HIS A 194
 None
 1.49A 1v54A-4fibA:
undetectable
1v54C-4fibA:
undetectable		 1v54A-4fibA:
16.96
1v54C-4fibA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 4fib UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 170
TYR A 114
HIS A 194
 None
 1.48A 1v54N-4fibA:
undetectable
1v54P-4fibA:
undetectable		 1v54N-4fibA:
16.96
1v54P-4fibA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4fib UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 170
TYR A 114
HIS A 194
 None
 1.48A 2dyrA-4fibA:
undetectable
2dyrC-4fibA:
undetectable		 2dyrA-4fibA:
16.96
2dyrC-4fibA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4fib UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 170
TYR A 114
HIS A 194
 None
 1.50A 2eijA-4fibA:
undetectable
2eijC-4fibA:
undetectable		 2eijA-4fibA:
16.96
2eijC-4fibA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4fib UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 170
TYR A 114
HIS A 194
 None
 1.48A 2eijN-4fibA:
undetectable
2eijP-4fibA:
undetectable		 2eijN-4fibA:
16.96
2eijP-4fibA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4fib UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 170
TYR A 114
HIS A 194
 None
 1.48A 2eikA-4fibA:
undetectable
2eikC-4fibA:
undetectable		 2eikA-4fibA:
16.96
2eikC-4fibA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4fib UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 170
TYR A 114
HIS A 194
 None
 1.47A 2eikN-4fibA:
undetectable
2eikP-4fibA:
undetectable		 2eikN-4fibA:
16.96
2eikP-4fibA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4fib UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 170
TYR A 114
HIS A 194
 None
 1.49A 2eilN-4fibA:
undetectable
2eilP-4fibA:
undetectable		 2eilN-4fibA:
16.96
2eilP-4fibA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CHDA1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4fib UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 170
TYR A 114
HIS A 194
 None
 1.50A 2y69A-4fibA:
undetectable
2y69C-4fibA:
undetectable		 2y69A-4fibA:
16.96
2y69C-4fibA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4fib UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 170
TYR A 114
HIS A 194
 None
 1.49A 3abkA-4fibA:
undetectable
3abkC-4fibA:
undetectable		 3abkA-4fibA:
16.96
3abkC-4fibA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4fib UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 170
TYR A 114
HIS A 194
 None
 1.47A 3abkN-4fibA:
undetectable
3abkP-4fibA:
undetectable		 3abkN-4fibA:
16.96
3abkP-4fibA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4fib UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		4 / 6 HIS A 158
ASP A 170
TYR A 114
HIS A 194
 None
 1.47A 3ag1A-4fibA:
undetectable
3ag1C-4fibA:
undetectable		 3ag1A-4fibA:
16.96
3ag1C-4fibA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4fib UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		4 / 6 HIS A 158
ASP A 170
TYR A 114
HIS A 194
 None
 1.48A 3ag1N-4fibA:
undetectable
3ag1P-4fibA:
undetectable		 3ag1N-4fibA:
16.96
3ag1P-4fibA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4fib UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 170
TYR A 114
HIS A 194
 None
 1.50A 3ag2A-4fibA:
undetectable
3ag2C-4fibA:
undetectable		 3ag2A-4fibA:
16.96
3ag2C-4fibA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4fib UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 170
TYR A 114
HIS A 194
 None
 1.50A 3ag2N-4fibA:
undetectable
3ag2P-4fibA:
undetectable		 3ag2N-4fibA:
16.96
3ag2P-4fibA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4fib UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 170
TYR A 114
HIS A 194
 None
 1.48A 3ag3A-4fibA:
undetectable
3ag3C-4fibA:
undetectable		 3ag3A-4fibA:
16.96
3ag3C-4fibA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4fib UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 170
TYR A 114
HIS A 194
 None
 1.49A 3ag4N-4fibA:
undetectable
3ag4P-4fibA:
undetectable		 3ag4N-4fibA:
16.96
3ag4P-4fibA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4fib UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		4 / 6 HIS A 158
ASP A 170
TYR A 114
HIS A 194
 None
 1.50A 3asnA-4fibA:
undetectable
3asnC-4fibA:
undetectable		 3asnA-4fibA:
16.96
3asnC-4fibA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_C_SAMC800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 4fib UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		5 / 11 ILE A  90
ALA A 103
GLU A 204
GLY A 107
HIS A 194
 None
 1.27A 4e47C-4fibA:
undetectable		 4e47C-4fibA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J83_A_SAMA401_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 4fib UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		5 / 11 ILE A  90
ALA A 103
GLU A 204
GLY A 107
HIS A 194
 None
 1.28A 4j83A-4fibA:
undetectable		 4j83A-4fibA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 4fib UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		4 / 7 TYR A 178
GLU A 201
GLU A 199
GLU A 173
 None
 1.29A 4mi4A-4fibA:
undetectable
4mi4C-4fibA:
undetectable		 4mi4A-4fibA:
15.74
4mi4C-4fibA:
15.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4fib UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 170
TYR A 114
HIS A 194
 None
 1.48A 5b1bN-4fibA:
undetectable
5b1bP-4fibA:
undetectable		 5b1bN-4fibA:
16.96
5b1bP-4fibA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4fib UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 170
TYR A 114
HIS A 194
 None
 1.49A 5b3sN-4fibA:
undetectable
5b3sP-4fibA:
undetectable		 5b3sN-4fibA:
16.96
5b3sP-4fibA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_1
(SCRFP-TAG,GP41)		 4fib UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		5 / 12 GLY A  85
SER A  86
LYS A  83
LEU A 202
GLU A 204
 None
 1.29A 5nwvA-4fibA:
undetectable		 5nwvA-4fibA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4fib UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		4 / 6 HIS A 158
ASP A 170
TYR A 114
HIS A 194
 None
 1.48A 5x19N-4fibA:
undetectable
5x19P-4fibA:
undetectable		 5x19N-4fibA:
16.96
5x19P-4fibA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4fib UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		4 / 6 HIS A 158
ASP A 170
TYR A 114
HIS A 194
 None
 1.48A 6nknA-4fibA:
undetectable
6nknC-4fibA:
undetectable		 6nknA-4fibA:
16.96
6nknC-4fibA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4fib UNCHARACTERIZED
PROTEIN YDHK
(Bacillus
subtilis) 		4 / 7 HIS A 158
ASP A 170
TYR A 114
HIS A 194
 None
 1.48A 6nmfN-4fibA:
undetectable
6nmfP-4fibA:
undetectable		 6nmfN-4fibA:
16.96
6nmfP-4fibA:
19.51