SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fid'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_A_V2HA602_1
(CYTOCHROME P450 2R1)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		4 / 5 ALA A 213
LEU A 268
GLY A 284
THR A 293
 None
 0.97A 3dl9A-4fidA:
undetectable		 3dl9A-4fidA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E22_B_LOCB700_2
(TUBULIN BETA-2B
CHAIN)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		5 / 11 LEU A 250
ALA A 340
ASN A 347
MET A 348
VAL A  26
 None
 1.27A 3e22B-4fidA:
3.4		 3e22B-4fidA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E22_D_LOCD700_2
(TUBULIN BETA-2B
CHAIN)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		5 / 11 LEU A 250
ALA A 340
ASN A 347
MET A 348
VAL A  26
 None
 1.28A 3e22D-4fidA:
2.0		 3e22D-4fidA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J7Z_A_ERYA9000_0
(23S RRNA
50S RIBOSOMAL
PROTEIN L22
ERMCL NASCENT CHAIN)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		3 / 3 LYS A 353
ILE A 207
PHE A 208
 None
 1.00A 3j7zS-4fidA:
undetectable
3j7za-4fidA:
undetectable		 3j7zS-4fidA:
16.72
3j7za-4fidA:
3.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_A_TFPA202_1
(PROTEIN S100-A4)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		5 / 12 LEU A 228
SER A 231
ILE A 288
PHE A 252
GLU A 214
 None
 1.17A 3ko0A-4fidA:
undetectable
3ko0B-4fidA:
undetectable
3ko0C-4fidA:
undetectable
3ko0D-4fidA:
undetectable		 3ko0A-4fidA:
15.16
3ko0B-4fidA:
15.16
3ko0C-4fidA:
15.16
3ko0D-4fidA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_A_TFPA202_1
(PROTEIN S100-A4)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		5 / 12 LEU A 228
SER A 231
PHE A 252
GLU A 214
PHE A 208
 None
 1.12A 3ko0A-4fidA:
undetectable
3ko0B-4fidA:
undetectable
3ko0C-4fidA:
undetectable
3ko0D-4fidA:
undetectable		 3ko0A-4fidA:
15.16
3ko0B-4fidA:
15.16
3ko0C-4fidA:
15.16
3ko0D-4fidA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_C_TFPC202_1
(PROTEIN S100-A4)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		5 / 11 LEU A 228
SER A 231
ILE A 288
PHE A 252
GLU A 214
 None
 1.22A 3ko0A-4fidA:
undetectable
3ko0B-4fidA:
undetectable
3ko0C-4fidA:
undetectable
3ko0D-4fidA:
undetectable		 3ko0A-4fidA:
15.16
3ko0B-4fidA:
15.16
3ko0C-4fidA:
15.16
3ko0D-4fidA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_C_TFPC202_1
(PROTEIN S100-A4)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		5 / 11 PHE A 208
LEU A 228
SER A 231
PHE A 252
GLU A 214
 None
 1.19A 3ko0A-4fidA:
undetectable
3ko0B-4fidA:
undetectable
3ko0C-4fidA:
undetectable
3ko0D-4fidA:
undetectable		 3ko0A-4fidA:
15.16
3ko0B-4fidA:
15.16
3ko0C-4fidA:
15.16
3ko0D-4fidA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD202_1
(PROTEIN S100-A4)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		5 / 11 GLU A 214
LEU A 228
SER A 231
ILE A 288
PHE A 252
 None
 1.24A 3ko0C-4fidA:
undetectable
3ko0D-4fidA:
undetectable
3ko0E-4fidA:
undetectable
3ko0F-4fidA:
undetectable		 3ko0C-4fidA:
15.16
3ko0D-4fidA:
15.16
3ko0E-4fidA:
15.16
3ko0F-4fidA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD202_1
(PROTEIN S100-A4)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		5 / 11 GLU A 214
LEU A 228
SER A 231
PHE A 252
PHE A 208
 None
 1.17A 3ko0C-4fidA:
undetectable
3ko0D-4fidA:
undetectable
3ko0E-4fidA:
undetectable
3ko0F-4fidA:
undetectable		 3ko0C-4fidA:
15.16
3ko0D-4fidA:
15.16
3ko0E-4fidA:
15.16
3ko0F-4fidA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE202_1
(PROTEIN S100-A4)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		5 / 11 LEU A 228
SER A 231
ILE A 288
PHE A 252
GLU A 214
 None
 1.21A 3ko0C-4fidA:
undetectable
3ko0D-4fidA:
undetectable
3ko0E-4fidA:
undetectable
3ko0F-4fidA:
undetectable		 3ko0C-4fidA:
15.16
3ko0D-4fidA:
15.16
3ko0E-4fidA:
15.16
3ko0F-4fidA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_E_TFPE202_1
(PROTEIN S100-A4)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		5 / 11 PHE A 208
LEU A 228
SER A 231
PHE A 252
GLU A 214
 None
 1.17A 3ko0C-4fidA:
undetectable
3ko0D-4fidA:
undetectable
3ko0E-4fidA:
undetectable
3ko0F-4fidA:
undetectable		 3ko0C-4fidA:
15.16
3ko0D-4fidA:
15.16
3ko0E-4fidA:
15.16
3ko0F-4fidA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_F_TFPF202_1
(PROTEIN S100-A4)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		5 / 11 GLU A 214
LEU A 228
SER A 231
ILE A 288
PHE A 252
 None
 1.30A 3ko0E-4fidA:
undetectable
3ko0F-4fidA:
undetectable
3ko0G-4fidA:
undetectable
3ko0H-4fidA:
undetectable		 3ko0E-4fidA:
15.16
3ko0F-4fidA:
15.16
3ko0G-4fidA:
15.16
3ko0H-4fidA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_F_TFPF202_1
(PROTEIN S100-A4)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		5 / 11 GLU A 214
LEU A 228
SER A 231
PHE A 252
PHE A 208
 None
 1.23A 3ko0E-4fidA:
undetectable
3ko0F-4fidA:
undetectable
3ko0G-4fidA:
undetectable
3ko0H-4fidA:
undetectable		 3ko0E-4fidA:
15.16
3ko0F-4fidA:
15.16
3ko0G-4fidA:
15.16
3ko0H-4fidA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_H_TFPH202_1
(PROTEIN S100-A4)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		5 / 12 GLU A 214
LEU A 228
SER A 231
ILE A 288
PHE A 252
 None
 1.28A 3ko0G-4fidA:
undetectable
3ko0H-4fidA:
undetectable
3ko0I-4fidA:
undetectable
3ko0J-4fidA:
undetectable		 3ko0G-4fidA:
15.16
3ko0H-4fidA:
15.16
3ko0I-4fidA:
15.16
3ko0J-4fidA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_H_TFPH202_1
(PROTEIN S100-A4)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		5 / 12 GLU A 214
LEU A 228
SER A 231
PHE A 252
PHE A 208
 None
 1.20A 3ko0G-4fidA:
undetectable
3ko0H-4fidA:
undetectable
3ko0I-4fidA:
undetectable
3ko0J-4fidA:
undetectable		 3ko0G-4fidA:
15.16
3ko0H-4fidA:
15.16
3ko0I-4fidA:
15.16
3ko0J-4fidA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_I_TFPI202_1
(PROTEIN S100-A4)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		5 / 12 LEU A 228
SER A 231
ILE A 288
PHE A 252
GLU A 214
 None
 1.20A 3ko0G-4fidA:
undetectable
3ko0H-4fidA:
undetectable
3ko0I-4fidA:
undetectable
3ko0J-4fidA:
undetectable		 3ko0G-4fidA:
15.16
3ko0H-4fidA:
15.16
3ko0I-4fidA:
15.16
3ko0J-4fidA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_I_TFPI202_1
(PROTEIN S100-A4)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		5 / 12 PHE A 208
LEU A 228
SER A 231
PHE A 252
GLU A 214
 None
 1.06A 3ko0G-4fidA:
undetectable
3ko0H-4fidA:
undetectable
3ko0I-4fidA:
undetectable
3ko0J-4fidA:
undetectable		 3ko0G-4fidA:
15.16
3ko0H-4fidA:
15.16
3ko0I-4fidA:
15.16
3ko0J-4fidA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_K_TFPK202_1
(PROTEIN S100-A4)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		5 / 12 LEU A 228
SER A 231
PHE A 252
GLU A 214
PHE A 208
 None
 1.13A 3ko0K-4fidA:
undetectable
3ko0L-4fidA:
undetectable
3ko0S-4fidA:
undetectable
3ko0T-4fidA:
undetectable		 3ko0K-4fidA:
15.16
3ko0L-4fidA:
15.16
3ko0S-4fidA:
15.16
3ko0T-4fidA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL202_1
(PROTEIN S100-A4)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		5 / 12 GLU A 214
LEU A 228
SER A 231
ILE A 288
PHE A 252
 None
 1.23A 3ko0K-4fidA:
undetectable
3ko0L-4fidA:
undetectable
3ko0M-4fidA:
undetectable
3ko0N-4fidA:
undetectable		 3ko0K-4fidA:
15.16
3ko0L-4fidA:
15.16
3ko0M-4fidA:
15.16
3ko0N-4fidA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL202_1
(PROTEIN S100-A4)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		5 / 12 GLU A 214
LEU A 228
SER A 231
PHE A 252
PHE A 208
 None
 1.10A 3ko0K-4fidA:
undetectable
3ko0L-4fidA:
undetectable
3ko0M-4fidA:
undetectable
3ko0N-4fidA:
undetectable		 3ko0K-4fidA:
15.16
3ko0L-4fidA:
15.16
3ko0M-4fidA:
15.16
3ko0N-4fidA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM202_1
(PROTEIN S100-A4)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		5 / 12 LEU A 228
SER A 231
ILE A 288
PHE A 252
GLU A 214
 None
 1.22A 3ko0M-4fidA:
undetectable
3ko0N-4fidA:
undetectable
3ko0O-4fidA:
undetectable
3ko0P-4fidA:
undetectable		 3ko0M-4fidA:
15.16
3ko0N-4fidA:
15.16
3ko0O-4fidA:
15.16
3ko0P-4fidA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM202_1
(PROTEIN S100-A4)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		5 / 12 LEU A 228
SER A 231
PHE A 252
GLU A 214
PHE A 208
 None
 1.13A 3ko0M-4fidA:
undetectable
3ko0N-4fidA:
undetectable
3ko0O-4fidA:
undetectable
3ko0P-4fidA:
undetectable		 3ko0M-4fidA:
15.16
3ko0N-4fidA:
15.16
3ko0O-4fidA:
15.16
3ko0P-4fidA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_N_TFPN202_1
(PROTEIN S100-A4)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		5 / 11 GLU A 214
LEU A 228
SER A 231
ILE A 288
PHE A 252
 None
 1.29A 3ko0K-4fidA:
undetectable
3ko0L-4fidA:
undetectable
3ko0M-4fidA:
undetectable
3ko0N-4fidA:
undetectable		 3ko0K-4fidA:
15.16
3ko0L-4fidA:
15.16
3ko0M-4fidA:
15.16
3ko0N-4fidA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_N_TFPN202_1
(PROTEIN S100-A4)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		5 / 11 PHE A 208
GLU A 214
LEU A 228
SER A 231
PHE A 252
 None
 1.19A 3ko0K-4fidA:
undetectable
3ko0L-4fidA:
undetectable
3ko0M-4fidA:
undetectable
3ko0N-4fidA:
undetectable		 3ko0K-4fidA:
15.16
3ko0L-4fidA:
15.16
3ko0M-4fidA:
15.16
3ko0N-4fidA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO202_1
(PROTEIN S100-A4)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		5 / 11 LEU A 228
SER A 231
ILE A 288
PHE A 252
GLU A 214
 None
 1.18A 3ko0O-4fidA:
undetectable
3ko0P-4fidA:
undetectable
3ko0Q-4fidA:
undetectable
3ko0R-4fidA:
undetectable		 3ko0O-4fidA:
15.16
3ko0P-4fidA:
15.16
3ko0Q-4fidA:
15.16
3ko0R-4fidA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO202_1
(PROTEIN S100-A4)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		5 / 11 LEU A 228
SER A 231
PHE A 252
GLU A 214
PHE A 208
 None
 1.12A 3ko0O-4fidA:
undetectable
3ko0P-4fidA:
undetectable
3ko0Q-4fidA:
undetectable
3ko0R-4fidA:
undetectable		 3ko0O-4fidA:
15.16
3ko0P-4fidA:
15.16
3ko0Q-4fidA:
15.16
3ko0R-4fidA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP202_1
(PROTEIN S100-A4)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		5 / 12 GLU A 214
LEU A 228
SER A 231
ILE A 288
PHE A 252
 None
 1.16A 3ko0M-4fidA:
undetectable
3ko0N-4fidA:
undetectable
3ko0O-4fidA:
undetectable
3ko0P-4fidA:
undetectable		 3ko0M-4fidA:
15.16
3ko0N-4fidA:
15.16
3ko0O-4fidA:
15.16
3ko0P-4fidA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP202_1
(PROTEIN S100-A4)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		5 / 12 PHE A 208
GLU A 214
LEU A 228
SER A 231
PHE A 252
 None
 1.13A 3ko0M-4fidA:
undetectable
3ko0N-4fidA:
undetectable
3ko0O-4fidA:
undetectable
3ko0P-4fidA:
undetectable		 3ko0M-4fidA:
15.16
3ko0N-4fidA:
15.16
3ko0O-4fidA:
15.16
3ko0P-4fidA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ202_1
(PROTEIN S100-A4)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		5 / 10 LEU A 228
SER A 231
ILE A 288
PHE A 252
GLU A 214
 None
 1.21A 3ko0O-4fidA:
undetectable
3ko0P-4fidA:
undetectable
3ko0Q-4fidA:
undetectable
3ko0R-4fidA:
undetectable		 3ko0O-4fidA:
15.16
3ko0P-4fidA:
15.16
3ko0Q-4fidA:
15.16
3ko0R-4fidA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_Q_TFPQ202_1
(PROTEIN S100-A4)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		5 / 10 PHE A 208
LEU A 228
SER A 231
PHE A 252
GLU A 214
 None
 1.16A 3ko0O-4fidA:
undetectable
3ko0P-4fidA:
undetectable
3ko0Q-4fidA:
undetectable
3ko0R-4fidA:
undetectable		 3ko0O-4fidA:
15.16
3ko0P-4fidA:
15.16
3ko0Q-4fidA:
15.16
3ko0R-4fidA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_T_TFPT202_1
(PROTEIN S100-A4)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		5 / 11 GLU A 214
LEU A 228
SER A 231
ILE A 288
PHE A 252
 None
 1.15A 3ko0Q-4fidA:
undetectable
3ko0R-4fidA:
undetectable
3ko0S-4fidA:
undetectable
3ko0T-4fidA:
undetectable		 3ko0Q-4fidA:
15.16
3ko0R-4fidA:
15.16
3ko0S-4fidA:
15.16
3ko0T-4fidA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_T_TFPT202_1
(PROTEIN S100-A4)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		5 / 11 PHE A 208
GLU A 214
LEU A 228
SER A 231
PHE A 252
 None
 1.04A 3ko0Q-4fidA:
undetectable
3ko0R-4fidA:
undetectable
3ko0S-4fidA:
undetectable
3ko0T-4fidA:
undetectable		 3ko0Q-4fidA:
15.16
3ko0R-4fidA:
15.16
3ko0S-4fidA:
15.16
3ko0T-4fidA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M0W_E_P77E203_1
(PROTEIN S100-A4)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		4 / 8 ASP A 111
SER A  91
PHE A 104
LEU A 140
 None
 0.99A 3m0wE-4fidA:
undetectable
3m0wF-4fidA:
undetectable
3m0wG-4fidA:
undetectable
3m0wH-4fidA:
undetectable		 3m0wE-4fidA:
15.25
3m0wF-4fidA:
15.25
3m0wG-4fidA:
15.25
3m0wH-4fidA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRJ_A_RAPA201_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4
SERINE/THREONINE-PRO
TEIN KINASE MTOR)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		4 / 8 LEU A 212
SER A 211
THR A 229
TYR A 215
 None
 1.08A 4drjB-4fidA:
undetectable		 4drjB-4fidA:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_B_MXMB807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		5 / 12 LEU A  43
ILE A 207
VAL A 209
LEU A  28
ALA A 327
 None
None
None
None
GDP  A 401 (-3.2A)
 1.10A 4o1zB-4fidA:
undetectable		 4o1zB-4fidA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8Y_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		5 / 12 GLY A  30
SER A  31
GLU A 230
ASP A 237
ILE A 238
 None
 1.11A 4u8yB-4fidA:
undetectable		 4u8yB-4fidA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U95_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		5 / 12 GLY A  30
SER A  31
GLU A 230
ASP A 237
ILE A 238
 None
 1.12A 4u95B-4fidA:
undetectable		 4u95B-4fidA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_D_LOCD502_2
(TUBULIN BETA CHAIN)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		5 / 12 LEU A 250
ASN A 347
MET A 348
VAL A  26
ILE A  24
 None
 1.10A 4x1kD-4fidA:
5.6		 4x1kD-4fidA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_B_LOCB502_1
(TUBULIN BETA CHAIN)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		5 / 12 LEU A 250
ASN A 347
MET A 348
VAL A  26
ILE A  24
 None
 1.08A 4x1yB-4fidA:
2.1		 4x1yB-4fidA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1Y_D_LOCD502_2
(TUBULIN BETA CHAIN)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		5 / 12 LEU A 250
ASN A 347
MET A 348
VAL A  26
ILE A  24
 None
 1.05A 4x1yD-4fidA:
5.6		 4x1yD-4fidA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_D_LOCD502_2
(TUBULIN BETA CHAIN)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		5 / 11 LEU A 250
ASN A 347
MET A 348
VAL A  26
ILE A  24
 None
 0.99A 4x20D-4fidA:
2.9		 4x20D-4fidA:
20.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE1_A_X2NA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		5 / 12 GLY A 277
LEU A 253
PHE A 208
PHE A 292
PHE A 259
 None
 1.29A 4ze1A-4fidA:
undetectable		 4ze1A-4fidA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_A_SORA1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		4 / 6 ASP A 237
LYS A 194
ARG A 193
ILE A 238
 None
 1.07A 5a06A-4fidA:
4.9		 5a06A-4fidA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_B_SORB1343_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		4 / 5 ASP A 237
LYS A 194
ARG A 193
ILE A 238
 None
 1.09A 5a06B-4fidA:
4.2		 5a06B-4fidA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_D_SORD1344_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		4 / 5 ASP A 237
LYS A 194
ARG A 193
ILE A 238
 None
 1.07A 5a06D-4fidA:
5.1		 5a06D-4fidA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1344_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		4 / 5 ASP A 237
LYS A 194
ARG A 193
ILE A 238
 None
 1.06A 5a06F-4fidA:
5.1		 5a06F-4fidA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_I_Z80I401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		4 / 9 PHE A 199
VAL A 203
THR A  25
ILE A 184
 None
 0.97A 5lg3I-4fidA:
undetectable		 5lg3I-4fidA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJE_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		5 / 12 PHE A 259
LEU A 263
ALA A 281
LEU A 291
LEU A 228
 None
 1.12A 5ljeA-4fidA:
undetectable		 5ljeA-4fidA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM2_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 4fid G PROTEIN ALPHA
SUBUNIT
(Entamoeba
histolytica) 		5 / 9 LEU A  43
PHE A 174
VAL A  26
HIS A 182
ILE A 207
 None
 1.19A 5om2A-4fidA:
undetectable
5om2B-4fidA:
undetectable		 5om2A-4fidA:
13.31
5om2B-4fidA:
9.71