SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fiu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_F_BEZF5023_0
(CES1 PROTEIN)		 4fiu HEMAGGLUTININ
(Influenza
A
virus) 		4 / 6 GLY A 247
SER A 245
LEU A 214
ILE A 181
 None
 0.95A 1yajF-4fiuA:
undetectable		 1yajF-4fiuA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_B_SAMB2002_1
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 4fiu HEMAGGLUTININ
(Influenza
A
virus) 		4 / 7 TYR A  12
TYR A 350
GLY A 318
ASP A  22
 None
 1.10A 2g72B-4fiuA:
undetectable		 2g72B-4fiuA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_B_CHDB504_0
(FERROCHELATASE)		 4fiu HEMAGGLUTININ
(Influenza
A
virus) 		4 / 6 ILE A 130
PRO A 184
SER A 226
MET A 228
 None
 1.21A 2qd3B-4fiuA:
undetectable		 2qd3B-4fiuA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_1
(AAC(6')-IB)		 4fiu HEMAGGLUTININ
(Influenza
A
virus) 		5 / 12 GLY A 318
TYR A  12
LEU A 330
ASP A 437
ASP A 433
 None
 1.40A 2vqyA-4fiuA:
undetectable		 2vqyA-4fiuA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_E_ZPCE1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4fiu HEMAGGLUTININ
(Influenza
A
virus) 		4 / 6 GLU A  63
HIS A 108
VAL A 113
PHE A  62
 None
 1.16A 4a97E-4fiuA:
undetectable		 4a97E-4fiuA:
20.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_B_VORB590_1
(14-ALPHA STEROL
DEMETHYLASE)		 4fiu HEMAGGLUTININ
(Influenza
A
virus) 		4 / 7 TYR A 194
TYR A 160
ALA A 251
ILE A 181
 None
 1.11A 4uymB-4fiuA:
undetectable		 4uymB-4fiuA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_D_29SD601_1
(ESTROGEN RECEPTOR)		 4fiu HEMAGGLUTININ
(Influenza
A
virus) 		5 / 12 THR A 369
ALA A 372
GLU A 375
LEU A 438
LEU A 319
 None
 1.16A 4xi3D-4fiuA:
undetectable		 4xi3D-4fiuA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_B_HISB302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 4fiu HEMAGGLUTININ
(Influenza
A
virus) 		5 / 10 GLY A  28
VAL A  21
THR A  25
VAL A  29
LEU A 436
 None
 1.28A 4yb6B-4fiuA:
undetectable
4yb6C-4fiuA:
undetectable		 4yb6B-4fiuA:
21.31
4yb6C-4fiuA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TRQ_B_ACTB306_0
(WELO5)		 4fiu HEMAGGLUTININ
(Influenza
A
virus) 		3 / 3 GLU A 120
ARG A 253
TYR A 254
 None
 0.38A 5trqB-4fiuA:
undetectable		 5trqB-4fiuA:
19.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM0_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 4fiu HEMAGGLUTININ
(Influenza
A
virus) 		5 / 10 LEU A  37
ASP A  36
ILE A 376
SER A  34
GLY A 318
 None
 1.13A 6dm0B-4fiuA:
undetectable
6dm0C-4fiuA:
undetectable		 6dm0B-4fiuA:
9.51
6dm0C-4fiuA:
9.51