SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fk7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DZM_A_BZMA600_0 (ODORANT-BINDING PROTEIN)	4fk7	PUTATIVE ADP-RIBOSYLTRANSFERA SE CERTHRAX (Bacillus cereus)	4 / 8	ILE A 381 ASN A 288 ASN A 384 GLY A 437	None	0.80A	1dzmA-4fk7A: undetectable	1dzmA-4fk7A: 25.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1SBR_A_VIBA501_1 (YKOF)	4fk7	PUTATIVE ADP-RIBOSYLTRANSFERA SE CERTHRAX (Bacillus cereus)	4 / 8	LEU A 337 ILE A 467 ILE A 411 THR A 388	None	0.97A	1sbrA-4fk7A: undetectable	1sbrA-4fk7A: 21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2C8A_A_NCAA1252_0 (MONO-ADP-RIBOSYLTRAN SFERASE C3)	4fk7	PUTATIVE ADP-RIBOSYLTRANSFERA SE CERTHRAX (Bacillus cereus)	5 / 7	ARG A 341 SER A 387 SER A 389 GLN A 429 GLU A 431	P34 A1001 (-3.6A) P34 A1001 (-4.0A) P34 A1001 (-3.1A) UNX A1011 ( 3.4A) P34 A1001 (-3.9A)	0.58A	2c8aA-4fk7A: 24.6	2c8aA-4fk7A: 27.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2C8A_B_NCAB1246_0 (MONO-ADP-RIBOSYLTRAN SFERASE C3)	4fk7	PUTATIVE ADP-RIBOSYLTRANSFERA SE CERTHRAX (Bacillus cereus)	4 / 7	ARG A 341 SER A 387 SER A 389 GLU A 431	P34 A1001 (-3.6A) P34 A1001 (-4.0A) P34 A1001 (-3.1A) P34 A1001 (-3.9A)	0.57A	2c8aB-4fk7A: 23.9	2c8aB-4fk7A: 27.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2C8A_C_NCAC1252_0 (MONO-ADP-RIBOSYLTRAN SFERASE C3)	4fk7	PUTATIVE ADP-RIBOSYLTRANSFERA SE CERTHRAX (Bacillus cereus)	4 / 6	ARG A 341 SER A 387 SER A 389 GLU A 431	P34 A1001 (-3.6A) P34 A1001 (-4.0A) P34 A1001 (-3.1A) P34 A1001 (-3.9A)	0.58A	2c8aC-4fk7A: 23.2	2c8aC-4fk7A: 27.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2C8A_D_NCAD1247_0 (MONO-ADP-RIBOSYLTRAN SFERASE C3)	4fk7	PUTATIVE ADP-RIBOSYLTRANSFERA SE CERTHRAX (Bacillus cereus)	4 / 7	ARG A 341 SER A 387 SER A 389 GLU A 431	P34 A1001 (-3.6A) P34 A1001 (-4.0A) P34 A1001 (-3.1A) P34 A1001 (-3.9A)	0.61A	2c8aD-4fk7A: 24.0	2c8aD-4fk7A: 27.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WRK_A_CAMA502_0 (CAMPHOR 5-MONOOXYGENASE)	4fk7	PUTATIVE ADP-RIBOSYLTRANSFERA SE CERTHRAX (Bacillus cereus)	4 / 5	PHE A 440 GLY A 417 ILE A 409 VAL A 339	None	0.70A	3wrkA-4fk7A: undetectable	3wrkA-4fk7A: 18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HZP_A_FVTA501_0 (PEPTIDE ABC TRANSPORTER PERMEASE)	4fk7	PUTATIVE ADP-RIBOSYLTRANSFERA SE CERTHRAX (Bacillus cereus)	4 / 8	TYR A 442 VAL A 463 GLN A 382 ILE A 409	None	1.07A	6hzpA-4fk7A: undetectable	6hzpA-4fk7A: 17.12

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DZM_A_BZMA600_0","ODORANT-BINDING PROTEIN","4fk7","PUTATIVE ADP-RIBOSYLTRANSFERASE CERTHRAX","Bacillus cereus",4,"ILE A 381;ASN A 288;ASN A 384;GLY A 437","None","0.80A","1dzmA-4fk7A:undetectable","1dzmA-4fk7A:25.32"],["1SBR_A_VIBA501_1","YKOF","4fk7","PUTATIVE ADP-RIBOSYLTRANSFERASE CERTHRAX","Bacillus cereus",4,"LEU A 337;ILE A 467;ILE A 411;THR A 388","None","0.97A","1sbrA-4fk7A:undetectable","1sbrA-4fk7A:21.85"],["2C8A_A_NCAA1252_0","MONO-ADP-RIBOSYLTRANSFERASE C3","4fk7","PUTATIVE ADP-RIBOSYLTRANSFERASE CERTHRAX","Bacillus cereus",5,"ARG A 341;SER A 387;SER A 389;GLN A 429;GLU A 431","P34 A1001 (-3.6A);P34 A1001 (-4.0A);P34 A1001 (-3.1A);UNX A1011 ( 3.4A);P34 A1001 (-3.9A)","0.58A","2c8aA-4fk7A:24.6","2c8aA-4fk7A:27.66"],["2C8A_B_NCAB1246_0","MONO-ADP-RIBOSYLTRANSFERASE C3","4fk7","PUTATIVE ADP-RIBOSYLTRANSFERASE CERTHRAX","Bacillus cereus",4,"ARG A 341;SER A 387;SER A 389;GLU A 431","P34 A1001 (-3.6A);P34 A1001 (-4.0A);P34 A1001 (-3.1A);P34 A1001 (-3.9A)","0.57A","2c8aB-4fk7A:23.9","2c8aB-4fk7A:27.66"],["2C8A_C_NCAC1252_0","MONO-ADP-RIBOSYLTRANSFERASE C3","4fk7","PUTATIVE ADP-RIBOSYLTRANSFERASE CERTHRAX","Bacillus cereus",4,"ARG A 341;SER A 387;SER A 389;GLU A 431","P34 A1001 (-3.6A);P34 A1001 (-4.0A);P34 A1001 (-3.1A);P34 A1001 (-3.9A)","0.58A","2c8aC-4fk7A:23.2","2c8aC-4fk7A:27.66"],["2C8A_D_NCAD1247_0","MONO-ADP-RIBOSYLTRANSFERASE C3","4fk7","PUTATIVE ADP-RIBOSYLTRANSFERASE CERTHRAX","Bacillus cereus",4,"ARG A 341;SER A 387;SER A 389;GLU A 431","P34 A1001 (-3.6A);P34 A1001 (-4.0A);P34 A1001 (-3.1A);P34 A1001 (-3.9A)","0.61A","2c8aD-4fk7A:24.0","2c8aD-4fk7A:27.66"],["3WRK_A_CAMA502_0","CAMPHOR 5-MONOOXYGENASE","4fk7","PUTATIVE ADP-RIBOSYLTRANSFERASE CERTHRAX","Bacillus cereus",4,"PHE A 440;GLY A 417;ILE A 409;VAL A 339","None","0.70A","3wrkA-4fk7A:undetectable","3wrkA-4fk7A:18.44"],["6HZP_A_FVTA501_0","PEPTIDE ABC TRANSPORTER PERMEASE","4fk7","PUTATIVE ADP-RIBOSYLTRANSFERASE CERTHRAX","Bacillus cereus",4,"TYR A 442;VAL A 463;GLN A 382;ILE A 409","None","1.07A","6hzpA-4fk7A:undetectable","6hzpA-4fk7A:17.12"]]