SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fmg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA8_0
(GRAMICIDIN A)		 4fmg VP1
(Human
polyomavirus
5) 		3 / 4 VAL A 318
TRP A 123
TRP A 317
 None
 1.34A 1gmkA-4fmgA:
undetectable
1gmkB-4fmgA:
undetectable		 1gmkA-4fmgA:
5.18
1gmkB-4fmgA:
5.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_1
(HIV-1 PROTEASE)		 4fmg VP1
(Human
polyomavirus
5) 		5 / 12 VAL A 311
ILE A 168
GLY A 169
GLY A 170
ILE A  55
 None
 0.75A 1hxbA-4fmgA:
undetectable		 1hxbA-4fmgA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_1
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 4fmg VP1
(Human
polyomavirus
5) 		5 / 12 GLY A 169
SER A 285
LEU A  57
LEU A 108
LEU A 220
 None
 1.23A 1zgyA-4fmgA:
undetectable		 1zgyA-4fmgA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DTJ_A_THRA401_0
(ASPARTOKINASE)		 4fmg VP1
(Human
polyomavirus
5) 		4 / 8 GLY A 274
GLU A 124
ALA A 125
ASN A 240
 None
 0.72A 2dtjA-4fmgA:
undetectable
2dtjB-4fmgA:
undetectable		 2dtjA-4fmgA:
22.53
2dtjB-4fmgA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_B_017B101_1
(PROTEASE)		 4fmg VP1
(Human
polyomavirus
5) 		5 / 11 VAL A 311
ILE A 168
GLY A 170
THR A  53
ILE A  55
 None
 0.91A 4njtA-4fmgA:
undetectable		 4njtA-4fmgA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_D_017D101_1
(PROTEASE)		 4fmg VP1
(Human
polyomavirus
5) 		5 / 11 VAL A 311
ILE A 168
GLY A 170
THR A  53
ILE A  55
 None
 0.92A 4njtC-4fmgA:
undetectable		 4njtC-4fmgA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_B_478B101_1
(HIV-1 PROTEASE)		 4fmg VP1
(Human
polyomavirus
5) 		5 / 11 VAL A 311
ILE A 168
GLY A 170
THR A  53
ILE A  55
 None
 0.96A 4rvjA-4fmgA:
undetectable		 4rvjA-4fmgA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_D_478D101_1
(HIV-1 PROTEASE)		 4fmg VP1
(Human
polyomavirus
5) 		5 / 11 VAL A 311
ILE A 168
GLY A 170
THR A  53
ILE A  55
 None
 0.95A 4rvjC-4fmgA:
undetectable		 4rvjC-4fmgA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5N_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 4fmg VP1
(Human
polyomavirus
5) 		4 / 4 TYR A  79
THR A  78
GLY A 304
LEU A 138
 None
 0.95A 4w5nA-4fmgA:
undetectable		 4w5nA-4fmgA:
15.03