SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fml'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTR_A_LQZA90_1
(LACTOTRANSFERRIN)		 4fml VSDC
(Aeromonas
hydrophila) 		3 / 3 PRO A 245
THR A 246
LEU A 241
 None
 0.69A 3ttrA-4fmlA:
undetectable		 3ttrA-4fmlA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FHB_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 4fml VSDC
(Aeromonas
hydrophila) 		5 / 12 PHE A 237
THR A 246
ILE A 244
LEU A 260
ILE A 257
 None
 0.97A 4fhbA-4fmlA:
undetectable		 4fhbA-4fmlA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)		 4fml VSDC
(Aeromonas
hydrophila) 		4 / 5 GLU A 173
THR A 222
GLU A 131
LEU A 204
 None
 1.16A 5hm8A-4fmlA:
undetectable		 5hm8A-4fmlA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_B_ADNB501_2
(ADENOSYLHOMOCYSTEINA
SE)		 4fml VSDC
(Aeromonas
hydrophila) 		4 / 5 GLU A 173
THR A 222
GLU A 131
LEU A 204
 None
 1.17A 5hm8B-4fmlA:
undetectable		 5hm8B-4fmlA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_C_ADNC501_2
(ADENOSYLHOMOCYSTEINA
SE)		 4fml VSDC
(Aeromonas
hydrophila) 		4 / 5 GLU A 173
THR A 222
GLU A 131
LEU A 204
 None
 1.16A 5hm8C-4fmlA:
undetectable		 5hm8C-4fmlA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_D_ADND501_2
(ADENOSYLHOMOCYSTEINA
SE)		 4fml VSDC
(Aeromonas
hydrophila) 		4 / 5 GLU A 173
THR A 222
GLU A 131
LEU A 204
 None
 1.16A 5hm8D-4fmlA:
undetectable		 5hm8D-4fmlA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_E_ADNE501_2
(ADENOSYLHOMOCYSTEINA
SE)		 4fml VSDC
(Aeromonas
hydrophila) 		4 / 5 GLU A 173
THR A 222
GLU A 131
LEU A 204
 None
 1.16A 5hm8E-4fmlA:
undetectable		 5hm8E-4fmlA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_F_ADNF501_2
(ADENOSYLHOMOCYSTEINA
SE)		 4fml VSDC
(Aeromonas
hydrophila) 		4 / 5 GLU A 173
THR A 222
GLU A 131
LEU A 204
 None
 1.16A 5hm8F-4fmlA:
undetectable		 5hm8F-4fmlA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_G_ADNG501_2
(ADENOSYLHOMOCYSTEINA
SE)		 4fml VSDC
(Aeromonas
hydrophila) 		4 / 5 GLU A 173
THR A 222
GLU A 131
LEU A 204
 None
 1.24A 5hm8G-4fmlA:
undetectable		 5hm8G-4fmlA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_H_ADNH501_2
(ADENOSYLHOMOCYSTEINA
SE)		 4fml VSDC
(Aeromonas
hydrophila) 		4 / 5 GLU A 173
THR A 222
GLU A 131
LEU A 204
 None
 1.17A 5hm8H-4fmlA:
undetectable		 5hm8H-4fmlA:
17.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNW_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 4fml VSDC
(Aeromonas
hydrophila) 		5 / 12 ASP A 182
GLU A 213
LEU A 224
LEU A 191
THR A 222
 None
 1.14A 5hnwB-4fmlA:
undetectable		 5hnwB-4fmlA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNY_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 4fml VSDC
(Aeromonas
hydrophila) 		5 / 12 ASP A 182
GLU A 213
LEU A 224
LEU A 191
THR A 222
 None
 1.14A 5hnyB-4fmlA:
undetectable		 5hnyB-4fmlA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8F_A_ACTA803_0
(UNCHARACTERIZED
PROTEIN)		 4fml VSDC
(Aeromonas
hydrophila) 		3 / 3 GLU A 131
LEU A 134
ARG A 202
 None
 0.81A 6d8fA-4fmlA:
undetectable		 6d8fA-4fmlA:
15.81