SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fmr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AW1_A_COXA264_1
(CARBONIC ANHYDRASE
II)		 4fmr UNCHARACTERIZED
HYPOTHETICAL PROTEIN
(Bacteroides
vulgatus) 		5 / 12 ILE A 185
VAL A 172
LEU A 213
VAL A 215
LEU A 156
 None
 0.95A 2aw1A-4fmrA:
undetectable		 2aw1A-4fmrA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGO_A_PCFA1213_1
(WNT INHIBITORY
FACTOR 1)		 4fmr UNCHARACTERIZED
HYPOTHETICAL PROTEIN
(Bacteroides
vulgatus) 		4 / 6 ILE A  37
ARG A  51
MET A  42
VAL A  75
 None
 1.15A 2ygoA-4fmrA:
undetectable		 2ygoA-4fmrA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RFQ_A_SAMA401_1
(HISTIDINE PROTEIN
METHYLTRANSFERASE 1
HOMOLOG)		 4fmr UNCHARACTERIZED
HYPOTHETICAL PROTEIN
(Bacteroides
vulgatus) 		4 / 4 THR A 179
GLY A 209
ASP A 208
SER A 176
 None
 1.13A 4rfqA-4fmrA:
undetectable		 4rfqA-4fmrA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TVT_A_ASCA301_0
(THAUMATIN-1)		 4fmr UNCHARACTERIZED
HYPOTHETICAL PROTEIN
(Bacteroides
vulgatus) 		3 / 3 THR A  99
ASN A 100
SER A 101
 None
 0.74A 4tvtA-4fmrA:
undetectable		 4tvtA-4fmrA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA610_0
(SERUM ALBUMIN)		 4fmr UNCHARACTERIZED
HYPOTHETICAL PROTEIN
(Bacteroides
vulgatus) 		3 / 3 TYR A 132
LYS A 159
LYS A 130
 None
 1.28A 5dbyA-4fmrA:
undetectable		 5dbyA-4fmrA:
19.58