SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fmv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CLA_A_CLMA221_0
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4fmv GLUCURONOARABINOXYLA
N
ENDO-1,4-BETA-XYLANA
SE
([Clostridium]
papyrosolvens) 		5 / 10 PHE A 372
ALA A 345
LEU A   9
VAL A 301
TYR A 298
 None
 1.04A 1claA-4fmvA:
undetectable		 1claA-4fmvA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K5Q_B_PACB559_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 4fmv GLUCURONOARABINOXYLA
N
ENDO-1,4-BETA-XYLANA
SE
([Clostridium]
papyrosolvens) 		4 / 7 MET A  34
ALA A 274
SER A  23
ALA A  21
 None
 0.92A 1k5qA-4fmvA:
undetectable
1k5qB-4fmvA:
undetectable		 1k5qA-4fmvA:
18.21
1k5qB-4fmvA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CC8_A_RBFA1067_1
(VNG1446H)		 4fmv GLUCURONOARABINOXYLA
N
ENDO-1,4-BETA-XYLANA
SE
([Clostridium]
papyrosolvens) 		3 / 3 PHE A 161
VAL A 140
TRP A 153
 None
 0.89A 2cc8A-4fmvA:
undetectable		 2cc8A-4fmvA:
9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CCB_A_RBFA1067_1
(VNG1446H)		 4fmv GLUCURONOARABINOXYLA
N
ENDO-1,4-BETA-XYLANA
SE
([Clostridium]
papyrosolvens) 		3 / 3 PHE A 161
VAL A 140
TRP A 153
 None
 0.88A 2ccbA-4fmvA:
undetectable		 2ccbA-4fmvA:
9.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_A_NBVA1503_1
(GLUCOSYLCERAMIDASE)		 4fmv GLUCURONOARABINOXYLA
N
ENDO-1,4-BETA-XYLANA
SE
([Clostridium]
papyrosolvens) 		7 / 12 TRP A  88
ASN A 142
GLU A 143
HIS A 205
TYR A 207
GLU A 232
TRP A 265
 None
 0.28A 2v3dA-4fmvA:
33.7		 2v3dA-4fmvA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_B_NBVB1504_1
(GLUCOSYLCERAMIDASE)		 4fmv GLUCURONOARABINOXYLA
N
ENDO-1,4-BETA-XYLANA
SE
([Clostridium]
papyrosolvens) 		6 / 11 TRP A  88
ASN A 142
GLU A 143
TYR A 207
GLU A 232
TRP A 265
 None
 0.30A 2v3dB-4fmvA:
33.6		 2v3dB-4fmvA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VX9_A_RBFA1064_1
(DODECIN)		 4fmv GLUCURONOARABINOXYLA
N
ENDO-1,4-BETA-XYLANA
SE
([Clostridium]
papyrosolvens) 		3 / 3 PHE A 161
VAL A 140
TRP A 153
 None
 0.88A 2vx9A-4fmvA:
undetectable		 2vx9A-4fmvA:
10.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6R_B_CTCB1385_0
(TETX2 PROTEIN)		 4fmv GLUCURONOARABINOXYLA
N
ENDO-1,4-BETA-XYLANA
SE
([Clostridium]
papyrosolvens) 		4 / 8 PHE A  19
GLY A  20
GLY A 297
MET A 254
 None
 0.76A 2y6rB-4fmvA:
undetectable		 2y6rB-4fmvA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOC_C_ERYC3402_0
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 4fmv GLUCURONOARABINOXYLA
N
ENDO-1,4-BETA-XYLANA
SE
([Clostridium]
papyrosolvens) 		5 / 12 MET A 199
MET A 162
ILE A 189
LEU A  48
GLU A  52
 None
 1.34A 3aocC-4fmvA:
undetectable		 3aocC-4fmvA:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 4fmv GLUCURONOARABINOXYLA
N
ENDO-1,4-BETA-XYLANA
SE
([Clostridium]
papyrosolvens) 		4 / 7 MET A 246
ILE A 327
PHE A 290
GLU A 249
 None
 1.46A 3e7gA-4fmvA:
0.5
3e7gB-4fmvA:
undetectable		 3e7gA-4fmvA:
22.39
3e7gB-4fmvA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_D_H4BD3902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 4fmv GLUCURONOARABINOXYLA
N
ENDO-1,4-BETA-XYLANA
SE
([Clostridium]
papyrosolvens) 		4 / 8 PHE A 290
GLU A 249
MET A 246
ILE A 327
 None
 1.46A 3e7gC-4fmvA:
undetectable
3e7gD-4fmvA:
undetectable		 3e7gC-4fmvA:
22.39
3e7gD-4fmvA:
22.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KL3_A_DHIA403_0
(GLUCURONOXYLANASE
XYNC)		 4fmv GLUCURONOARABINOXYLA
N
ENDO-1,4-BETA-XYLANA
SE
([Clostridium]
papyrosolvens) 		4 / 4 GLY A 297
TYR A 298
GLY A 318
ASP A 319
 None
 0.17A 3kl3A-4fmvA:
57.0		 3kl3A-4fmvA:
55.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KL3_B_DHIB404_0
(GLUCURONOXYLANASE
XYNC)		 4fmv GLUCURONOARABINOXYLA
N
ENDO-1,4-BETA-XYLANA
SE
([Clostridium]
papyrosolvens) 		4 / 4 GLU A 143
TYR A 146
TYR A 207
TYR A 234
 None
 0.41A 3kl3B-4fmvA:
56.9		 3kl3B-4fmvA:
55.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_C_BEZC264_0
(CARNITINYL-COA
DEHYDRATASE)		 4fmv GLUCURONOARABINOXYLA
N
ENDO-1,4-BETA-XYLANA
SE
([Clostridium]
papyrosolvens) 		4 / 6 ALA A 284
ILE A 280
LEU A  41
ALA A  21
 None
 0.81A 3r9sC-4fmvA:
undetectable		 3r9sC-4fmvA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_B_MIYB2001_1
(TETX2 PROTEIN)		 4fmv GLUCURONOARABINOXYLA
N
ENDO-1,4-BETA-XYLANA
SE
([Clostridium]
papyrosolvens) 		4 / 8 PHE A  19
GLY A  20
GLY A 297
MET A 254
 None
 0.70A 3v3nB-4fmvA:
undetectable		 3v3nB-4fmvA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_C_MIYC2001_1
(TETX2 PROTEIN)		 4fmv GLUCURONOARABINOXYLA
N
ENDO-1,4-BETA-XYLANA
SE
([Clostridium]
papyrosolvens) 		4 / 8 PHE A  19
GLY A  20
GLY A 297
MET A 254
 None
 0.70A 3v3nC-4fmvA:
undetectable		 3v3nC-4fmvA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_D_T1CD401_1
(TETX2 PROTEIN)		 4fmv GLUCURONOARABINOXYLA
N
ENDO-1,4-BETA-XYLANA
SE
([Clostridium]
papyrosolvens) 		5 / 10 ARG A 295
PHE A  19
GLY A  20
GLY A 297
MET A 254
 None
 1.41A 3v3oD-4fmvA:
undetectable		 3v3oD-4fmvA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTZ_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT 8C8)		 4fmv GLUCURONOARABINOXYLA
N
ENDO-1,4-BETA-XYLANA
SE
([Clostridium]
papyrosolvens) 		4 / 6 PHE A 372
ALA A 374
ALA A 326
THR A 382
 None
 0.92A 4dtzA-4fmvA:
undetectable		 4dtzA-4fmvA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIZ_A_LURA201_1
(TRANSTHYRETIN)		 4fmv GLUCURONOARABINOXYLA
N
ENDO-1,4-BETA-XYLANA
SE
([Clostridium]
papyrosolvens) 		3 / 3 LYS A 163
LEU A 159
ALA A 195
 None
 0.80A 4iizA-4fmvA:
undetectable		 4iizA-4fmvA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		 4fmv GLUCURONOARABINOXYLA
N
ENDO-1,4-BETA-XYLANA
SE
([Clostridium]
papyrosolvens) 		5 / 12 LEU A 287
GLY A 208
PHE A 235
MET A 214
THR A 209
 None
 1.18A 4mubA-4fmvA:
undetectable		 4mubA-4fmvA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XT8_A_TMQA302_1
(RV2671)		 4fmv GLUCURONOARABINOXYLA
N
ENDO-1,4-BETA-XYLANA
SE
([Clostridium]
papyrosolvens) 		5 / 12 ILE A 263
GLY A  18
ALA A 261
ARG A 172
THR A 231
 None
 1.12A 4xt8A-4fmvA:
2.0		 4xt8A-4fmvA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGV_A_ZITA404_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 4fmv GLUCURONOARABINOXYLA
N
ENDO-1,4-BETA-XYLANA
SE
([Clostridium]
papyrosolvens) 		4 / 4 ASN A 358
ILE A 267
TYR A 264
PHE A  19
 None
 1.45A 5igvA-4fmvA:
2.1		 5igvA-4fmvA:
23.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 4fmv GLUCURONOARABINOXYLA
N
ENDO-1,4-BETA-XYLANA
SE
([Clostridium]
papyrosolvens) 		3 / 3 THR A 256
MET A 254
HIS A 251
 None
 0.90A 5uunA-4fmvA:
undetectable		 5uunA-4fmvA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V1T_A_SAMA605_0
(RADICAL SAM)		 4fmv GLUCURONOARABINOXYLA
N
ENDO-1,4-BETA-XYLANA
SE
([Clostridium]
papyrosolvens) 		5 / 12 PHE A 338
LEU A 376
SER A 350
VAL A 348
SER A 371
 None
 1.46A 5v1tA-4fmvA:
2.6		 5v1tA-4fmvA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 4fmv GLUCURONOARABINOXYLA
N
ENDO-1,4-BETA-XYLANA
SE
([Clostridium]
papyrosolvens) 		4 / 7 PHE A 293
VAL A 323
ILE A 250
THR A 383
 None
 1.07A 5vkqA-4fmvA:
undetectable
5vkqD-4fmvA:
undetectable		 5vkqA-4fmvA:
12.70
5vkqD-4fmvA:
12.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B58_A_ACTA603_0
(FUMARATE REDUCTASE
FLAVOPROTEIN SUBUNIT)		 4fmv GLUCURONOARABINOXYLA
N
ENDO-1,4-BETA-XYLANA
SE
([Clostridium]
papyrosolvens) 		3 / 3 TYR A  38
ASN A  72
LEU A  46
 None
 0.70A 6b58A-4fmvA:
undetectable		 6b58A-4fmvA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 4fmv GLUCURONOARABINOXYLA
N
ENDO-1,4-BETA-XYLANA
SE
([Clostridium]
papyrosolvens) 		4 / 5 GLN A 336
VAL A 334
PRO A 307
THR A 331
 None
 1.39A 6cduA-4fmvA:
undetectable
6cduB-4fmvA:
undetectable		 6cduA-4fmvA:
20.35
6cduB-4fmvA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_B_EY4B500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 4fmv GLUCURONOARABINOXYLA
N
ENDO-1,4-BETA-XYLANA
SE
([Clostridium]
papyrosolvens) 		5 / 6 GLN A 336
VAL A 334
PRO A 307
ALA A 332
THR A 331
 None
 1.36A 6cduB-4fmvA:
undetectable
6cduC-4fmvA:
undetectable		 6cduB-4fmvA:
20.35
6cduC-4fmvA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_F_EY4F500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 4fmv GLUCURONOARABINOXYLA
N
ENDO-1,4-BETA-XYLANA
SE
([Clostridium]
papyrosolvens) 		5 / 7 ALA A 332
THR A 331
GLN A 336
VAL A 334
PRO A 307
 None
 1.39A 6cduF-4fmvA:
undetectable
6cduJ-4fmvA:
undetectable		 6cduF-4fmvA:
20.35
6cduJ-4fmvA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_I_EY4I500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 4fmv GLUCURONOARABINOXYLA
N
ENDO-1,4-BETA-XYLANA
SE
([Clostridium]
papyrosolvens) 		4 / 5 GLN A 336
VAL A 334
PRO A 307
THR A 331
 None
 1.35A 6cduI-4fmvA:
undetectable
6cduJ-4fmvA:
undetectable		 6cduI-4fmvA:
20.35
6cduJ-4fmvA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CNJ_D_NCTD402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 4fmv GLUCURONOARABINOXYLA
N
ENDO-1,4-BETA-XYLANA
SE
([Clostridium]
papyrosolvens) 		4 / 8 TYR A 264
THR A 268
TYR A 281
LEU A  37
 None
 1.25A 6cnjD-4fmvA:
undetectable
6cnjE-4fmvA:
undetectable		 6cnjD-4fmvA:
11.03
6cnjE-4fmvA:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_2
(SIALIDASE)		 4fmv GLUCURONOARABINOXYLA
N
ENDO-1,4-BETA-XYLANA
SE
([Clostridium]
papyrosolvens) 		4 / 6 GLN A  14
ASN A 258
SER A 253
PHE A  19
 None
 0.91A 6ekuA-4fmvA:
undetectable		 6ekuA-4fmvA:
18.98