SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fmz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHJ_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		5 / 12 ALA A  85
LEU A  82
ILE A  92
LEU A 117
ILE A 128
 None
 0.95A 1dhjA-4fmzA:
undetectable		 1dhjA-4fmzA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHJ_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		5 / 12 ALA A  85
LEU A  82
ILE A  92
LEU A 117
ILE A 128
 None
 0.91A 1dhjB-4fmzA:
undetectable		 1dhjB-4fmzA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRA_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		5 / 12 ALA A  85
LEU A  82
ILE A  92
LEU A 117
ILE A 128
 None
 0.96A 1draA-4fmzA:
undetectable		 1draA-4fmzA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRB_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		5 / 12 ALA A  85
LEU A  82
ILE A  92
LEU A 117
ILE A 128
 None
 0.93A 1drbA-4fmzA:
undetectable		 1drbA-4fmzA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DRB_B_MTXB361_1
(DIHYDROFOLATE
REDUCTASE)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		5 / 12 ALA A  85
LEU A  82
ILE A  92
LEU A 117
ILE A 128
 None
 0.92A 1drbB-4fmzA:
undetectable		 1drbB-4fmzA:
15.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA502_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		4 / 6 ASN A 175
ASN A 151
ILE A 128
GLY A 129
 None
 1.10A 1oniA-4fmzA:
undetectable
1oniB-4fmzA:
undetectable		 1oniA-4fmzA:
17.54
1oniB-4fmzA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHS_A_CLMA999_0
(PROTEIN
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE))		 4fmz INTERNALIN
(Listeria
monocytogenes) 		5 / 12 ILE A 244
ILE A 261
ILE A 283
LEU A 272
MET A 253
 None
 0.94A 1qhsA-4fmzA:
undetectable		 1qhsA-4fmzA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QHY_A_CLMA999_0
(CHLORAMPHENICOL
PHOSPHOTRANSFERASE)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		5 / 12 ILE A 244
ILE A 261
ILE A 283
LEU A 272
MET A 253
 None
 0.90A 1qhyA-4fmzA:
undetectable		 1qhyA-4fmzA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_A_FOLA605_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		5 / 12 VAL A 315
LEU A 327
LEU A 303
ILE A 288
LEU A 269
 None
 1.09A 1qzfA-4fmzA:
undetectable		 1qzfA-4fmzA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_B_FOLB609_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		5 / 12 VAL A 315
LEU A 327
LEU A 303
ILE A 288
LEU A 269
 None
 1.08A 1qzfB-4fmzA:
undetectable		 1qzfB-4fmzA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_C_FOLC613_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		5 / 12 VAL A 315
LEU A 327
LEU A 303
ILE A 288
LEU A 269
 None
 1.08A 1qzfC-4fmzA:
undetectable		 1qzfC-4fmzA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_D_FOLD617_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		5 / 12 VAL A 315
LEU A 327
LEU A 303
ILE A 288
LEU A 269
 None
 1.08A 1qzfD-4fmzA:
undetectable		 1qzfD-4fmzA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZF_E_FOLE621_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		5 / 12 VAL A 315
LEU A 327
LEU A 303
ILE A 288
LEU A 269
 None
 1.09A 1qzfE-4fmzA:
undetectable		 1qzfE-4fmzA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R5L_A_VIVA301_0
(PROTEIN
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN))		 4fmz INTERNALIN
(Listeria
monocytogenes) 		5 / 12 ILE A 288
ILE A 291
VAL A 315
VAL A 339
ILE A 310
 None
 1.17A 1r5lA-4fmzA:
undetectable		 1r5lA-4fmzA:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDT_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		5 / 10 LEU A 343
ILE A 356
ILE A 310
VAL A 339
ILE A 340
 None
EDO  A 405 (-3.8A)
None
None
None
 0.86A 1sdtA-4fmzA:
undetectable		 1sdtA-4fmzA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_B_CHDB1130_0
(FATTY ACID-BINDING
PROTEIN)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		5 / 12 LEU A 184
LEU A 161
LEU A 190
ILE A 155
LEU A 178
 None
 1.22A 1tw4B-4fmzA:
undetectable		 1tw4B-4fmzA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		4 / 7 ILE A 128
LEU A 150
THR A 124
LEU A 145
 None
 0.88A 1v55A-4fmzA:
undetectable
1v55J-4fmzA:
undetectable		 1v55A-4fmzA:
20.75
1v55J-4fmzA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVO_B_MK1B902_1
(POL POLYPROTEIN)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		5 / 9 LEU A 343
ILE A 356
ILE A 310
VAL A 339
ILE A 340
 None
EDO  A 405 (-3.8A)
None
None
None
 0.89A 2avoA-4fmzA:
undetectable		 2avoA-4fmzA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_1
(POL POLYPROTEIN)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		5 / 12 LEU A 343
ILE A 356
ILE A 310
VAL A 339
ILE A 340
 None
EDO  A 405 (-3.8A)
None
None
None
 0.79A 2avvA-4fmzA:
undetectable		 2avvA-4fmzA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRL_A_DXTA1211_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		5 / 12 SER A 216
PHE A 237
THR A 196
LEU A 181
ILE A 206
 EDO  A 401 (-4.5A)
None
None
None
None
 1.27A 2xrlA-4fmzA:
undetectable		 2xrlA-4fmzA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		4 / 6 LEU A 351
MET A 368
THR A 347
LEU A 346
 EDO  A 405 (-4.4A)
None
None
None
 1.10A 2zxwA-4fmzA:
undetectable
2zxwJ-4fmzA:
undetectable		 2zxwA-4fmzA:
20.75
2zxwJ-4fmzA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		4 / 7 ILE A 128
LEU A 150
THR A 124
LEU A 145
 None
 0.88A 3ag3A-4fmzA:
undetectable
3ag3J-4fmzA:
undetectable		 3ag3A-4fmzA:
20.75
3ag3J-4fmzA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D1Y_A_ROCA201_2
(HIV-1 PROTEASE)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		5 / 9 LEU A 343
ILE A 356
ILE A 310
VAL A 339
ILE A 340
 None
EDO  A 405 (-3.8A)
None
None
None
 1.03A 3d1yB-4fmzA:
undetectable		 3d1yB-4fmzA:
17.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TQ9_A_MTXA2001_1
(DIHYDROFOLATE
REDUCTASE)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		5 / 12 ALA A  85
LEU A  82
ILE A  92
LEU A 117
ILE A 128
 None
 1.04A 3tq9A-4fmzA:
undetectable		 3tq9A-4fmzA:
18.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_A_08JA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		4 / 8 VAL A 294
LEU A 281
LEU A 303
ILE A 288
 None
 0.81A 3u5kA-4fmzA:
undetectable		 3u5kA-4fmzA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_C_08JC3_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		4 / 8 VAL A 294
LEU A 281
LEU A 303
ILE A 288
 None
 0.84A 3u5kC-4fmzA:
undetectable		 3u5kC-4fmzA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		3 / 3 GLN A 140
THR A 143
ASN A 141
 None
 0.90A 3v4tE-4fmzA:
undetectable		 3v4tE-4fmzA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_A_TYLA1188_1
(BROMODOMAIN
CONTAINING 2)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		4 / 5 VAL A 294
LEU A 281
LEU A 303
ILE A 288
 None
 0.93A 4a9jA-4fmzA:
undetectable		 4a9jA-4fmzA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_B_TYLB1187_1
(BROMODOMAIN
CONTAINING 2)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		4 / 5 VAL A 294
LEU A 281
LEU A 303
ILE A 288
 None
 0.89A 4a9jB-4fmzA:
undetectable		 4a9jB-4fmzA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_C_TYLC1184_1
(BROMODOMAIN
CONTAINING 2)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		4 / 5 VAL A 294
LEU A 281
LEU A 303
ILE A 288
 None
 0.87A 4a9jC-4fmzA:
undetectable		 4a9jC-4fmzA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQB_B_017B101_1
(ASPARTYL PROTEASE)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		5 / 12 LEU A 343
ILE A 356
ILE A 310
VAL A 339
ILE A 340
 None
EDO  A 405 (-3.8A)
None
None
None
 0.73A 4dqbA-4fmzA:
undetectable		 4dqbA-4fmzA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQF_B_017B101_1
(ASPARTYL PROTEASE)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		5 / 12 LEU A 343
ILE A 356
ILE A 310
VAL A 339
ILE A 340
 None
EDO  A 405 (-3.8A)
None
None
None
 0.93A 4dqfA-4fmzA:
undetectable		 4dqfA-4fmzA:
16.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		4 / 7 ASP A 372
THR A 348
GLN A 331
LEU A 332
 None
 0.90A 4ib4A-4fmzA:
undetectable		 4ib4A-4fmzA:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_A_MXMA606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		5 / 12 MET A 167
LEU A 145
LEU A 178
LEU A 170
LEU A 139
 None
 1.25A 4m11A-4fmzA:
undetectable		 4m11A-4fmzA:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NX7_A_FOLA202_0
(DIHYDROFOLATE
REDUCTASE)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		5 / 12 ALA A  85
LEU A  82
ILE A  92
LEU A 117
ILE A 128
 None
 0.95A 4nx7A-4fmzA:
undetectable		 4nx7A-4fmzA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PST_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		5 / 12 ALA A  85
LEU A  82
ILE A  92
LEU A 117
ILE A 128
 None
 0.98A 4pstA-4fmzA:
undetectable		 4pstA-4fmzA:
15.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1X_A_017A101_2
(ASPARTYL PROTEASE)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		5 / 12 LEU A 343
ILE A 356
ILE A 310
VAL A 339
ILE A 340
 None
EDO  A 405 (-3.8A)
None
None
None
 0.76A 4q1xB-4fmzA:
undetectable		 4q1xB-4fmzA:
14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_2
(ASPARTYL PROTEASE)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		5 / 12 LEU A 343
ILE A 356
ILE A 310
VAL A 339
ILE A 340
 None
EDO  A 405 (-3.8A)
None
None
None
 0.92A 4q1yB-4fmzA:
undetectable		 4q1yB-4fmzA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QB9_E_PARE500_1
(ENHANCED
INTRACELLULAR
SURVIVAL PROTEIN)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		5 / 12 SER A 214
LEU A 193
THR A 194
SER A 169
GLU A 152
 EDO  A 401 (-2.7A)
None
EDO  A 401 (-4.2A)
None
None
 1.19A 4qb9E-4fmzA:
undetectable		 4qb9E-4fmzA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_0
(HYDG PROTEIN)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		5 / 12 VAL A 339
LEU A 346
LEU A 300
LEU A 297
ALA A 293
 None
 1.31A 4rtbA-4fmzA:
undetectable		 4rtbA-4fmzA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1F_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		5 / 12 LEU A 215
LEU A 217
SER A 198
LEU A 181
ILE A 206
 None
 1.13A 4x1fA-4fmzA:
undetectable		 4x1fA-4fmzA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_A_SALA801_1
(PROTEIN POLYBROMO-1)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		5 / 7 ILE A 225
LEU A 215
ALA A 239
ASN A 242
ILE A 244
 None
 1.35A 4y03A-4fmzA:
undetectable		 4y03A-4fmzA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		4 / 7 ILE A 128
LEU A 150
THR A 124
LEU A 145
 None
 0.84A 5b1aA-4fmzA:
undetectable
5b1aJ-4fmzA:
undetectable		 5b1aA-4fmzA:
20.75
5b1aJ-4fmzA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		4 / 7 ILE A 128
LEU A 150
THR A 124
LEU A 145
 None
 0.87A 5b3sA-4fmzA:
undetectable
5b3sJ-4fmzA:
undetectable		 5b3sA-4fmzA:
20.75
5b3sJ-4fmzA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_1
(PROTEASE PR5-DRV)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		5 / 10 LEU A 343
ILE A 356
ILE A 310
VAL A 339
ILE A 340
 None
EDO  A 405 (-3.8A)
None
None
None
 0.95A 5kr1A-4fmzA:
undetectable		 5kr1A-4fmzA:
18.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		4 / 7 ILE A 128
LEU A 150
THR A 124
LEU A 145
 None
 0.85A 5xdqN-4fmzA:
undetectable
5xdqW-4fmzA:
undetectable		 5xdqN-4fmzA:
20.75
5xdqW-4fmzA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		4 / 7 ILE A 128
LEU A 150
THR A 124
LEU A 145
 None
 0.87A 5xdxA-4fmzA:
undetectable
5xdxJ-4fmzA:
undetectable		 5xdxA-4fmzA:
20.75
5xdxJ-4fmzA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		4 / 7 ILE A 128
LEU A 150
THR A 124
LEU A 145
 None
 0.88A 5zcpA-4fmzA:
undetectable
5zcpJ-4fmzA:
undetectable		 5zcpA-4fmzA:
20.75
5zcpJ-4fmzA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		4 / 7 ILE A 128
LEU A 150
THR A 124
LEU A 145
 None
 0.88A 5zcqA-4fmzA:
undetectable
5zcqJ-4fmzA:
undetectable		 5zcqA-4fmzA:
20.75
5zcqJ-4fmzA:
11.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		4 / 7 ILE A  58
VAL A  71
ILE A  48
THR A  40
 None
 1.00A 6cduF-4fmzA:
undetectable
6cduG-4fmzA:
undetectable		 6cduF-4fmzA:
24.25
6cduG-4fmzA:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4fmz INTERNALIN
(Listeria
monocytogenes) 		4 / 5 ILE A 128
LEU A 150
THR A 124
LEU A 145
 None
 0.89A 6nmpN-4fmzA:
undetectable
6nmpW-4fmzA:
undetectable		 6nmpN-4fmzA:
20.75
6nmpW-4fmzA:
11.14