SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fnq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA8_0
(ACTINOMYCIN D)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		3 / 3 THR A 187
THR A 268
PRO A 186
 None
 0.80A 1a7yA-4fnqA:
undetectable		 1a7yA-4fnqA:
1.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		3 / 3 THR A 268
PRO A 186
THR A 187
 None
 0.77A 1a7yB-4fnqA:
undetectable		 1a7yB-4fnqA:
1.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC2_0
(ACTINOMYCIN D)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		3 / 3 THR A 268
PRO A 186
THR A 187
 None
 0.95A 1dscC-4fnqA:
undetectable		 1dscC-4fnqA:
1.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC8_0
(ACTINOMYCIN D)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		3 / 3 THR A 187
THR A 268
PRO A 186
 None
 0.77A 1dscC-4fnqA:
undetectable		 1dscC-4fnqA:
1.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FDS_A_ESTA350_1
(17-BETA-HYDROXYSTERO
ID-DEHYDROGENASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		5 / 12 SER A 180
LEU A 119
GLY A 274
TYR A 508
SER A 254
 None
 1.34A 1fdsA-4fnqA:
undetectable		 1fdsA-4fnqA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		3 / 3 THR A 187
THR A 268
PRO A 186
 None
 0.89A 1fjaC-4fnqA:
undetectable		 1fjaC-4fnqA:
1.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		3 / 3 THR A 187
THR A 268
PRO A 186
 None
 0.86A 1i3wE-4fnqA:
undetectable		 1i3wE-4fnqA:
1.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_F_DVAF8_0
(ACTINOMYCIN D)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		3 / 3 THR A 187
THR A 268
PRO A 186
 None
 0.82A 1i3wF-4fnqA:
undetectable		 1i3wF-4fnqA:
1.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		3 / 3 THR A 268
PRO A 186
THR A 187
 None
 0.88A 1i3wG-4fnqA:
undetectable		 1i3wG-4fnqA:
1.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		3 / 3 THR A 187
THR A 268
PRO A 186
 None
 0.78A 1i3wG-4fnqA:
undetectable		 1i3wG-4fnqA:
1.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		3 / 3 THR A 187
THR A 268
PRO A 186
 None
 0.81A 1i3wH-4fnqA:
undetectable		 1i3wH-4fnqA:
1.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IA0_B_TXLB502_1
(TUBULIN BETA CHAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		5 / 12 VAL A  43
ASP A  42
LEU A  31
SER A  20
ARG A  15
 None
 1.38A 1ia0B-4fnqA:
undetectable		 1ia0B-4fnqA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 1k2rA-4fnqA:
undetectable
1k2rB-4fnqA:
undetectable		 1k2rA-4fnqA:
20.92
1k2rB-4fnqA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2R_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.48A 1k2rA-4fnqA:
undetectable
1k2rB-4fnqA:
undetectable		 1k2rA-4fnqA:
20.92
1k2rB-4fnqA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.49A 1k2sA-4fnqA:
undetectable
1k2sB-4fnqA:
undetectable		 1k2sA-4fnqA:
20.92
1k2sB-4fnqA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2T_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.49A 1k2tA-4fnqA:
undetectable
1k2tB-4fnqA:
undetectable		 1k2tA-4fnqA:
20.92
1k2tB-4fnqA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.45A 1lzxA-4fnqA:
undetectable
1lzxB-4fnqA:
undetectable		 1lzxA-4fnqA:
20.92
1lzxB-4fnqA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.47A 1lzxA-4fnqA:
undetectable
1lzxB-4fnqA:
undetectable		 1lzxA-4fnqA:
20.92
1lzxB-4fnqA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 1lzzA-4fnqA:
undetectable
1lzzB-4fnqA:
undetectable		 1lzzA-4fnqA:
20.92
1lzzB-4fnqA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZZ_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.47A 1lzzA-4fnqA:
undetectable
1lzzB-4fnqA:
undetectable		 1lzzA-4fnqA:
20.92
1lzzB-4fnqA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.47A 1m00A-4fnqA:
undetectable
1m00B-4fnqA:
undetectable		 1m00A-4fnqA:
20.92
1m00B-4fnqA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.44A 1m00A-4fnqA:
undetectable
1m00B-4fnqA:
undetectable		 1m00A-4fnqA:
20.92
1m00B-4fnqA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.46A 1mmvA-4fnqA:
undetectable
1mmvB-4fnqA:
undetectable		 1mmvA-4fnqA:
20.92
1mmvB-4fnqA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMV_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.45A 1mmvA-4fnqA:
undetectable
1mmvB-4fnqA:
undetectable		 1mmvA-4fnqA:
20.92
1mmvB-4fnqA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.49A 1mmwA-4fnqA:
undetectable
1mmwB-4fnqA:
undetectable		 1mmwA-4fnqA:
20.92
1mmwB-4fnqA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MMW_B_H4BB2760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.46A 1mmwA-4fnqA:
undetectable
1mmwB-4fnqA:
undetectable		 1mmwA-4fnqA:
20.92
1mmwB-4fnqA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD2_0
(ACTINOMYCIN D)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		3 / 3 THR A 268
PRO A 186
THR A 187
 None
 0.82A 1mnvD-4fnqA:
undetectable		 1mnvD-4fnqA:
1.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD8_0
(ACTINOMYCIN D)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		3 / 3 THR A 187
THR A 268
PRO A 186
 None
 0.78A 1mnvD-4fnqA:
undetectable		 1mnvD-4fnqA:
1.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.47A 1om4A-4fnqA:
undetectable
1om4B-4fnqA:
undetectable		 1om4A-4fnqA:
20.73
1om4B-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.45A 1om4A-4fnqA:
undetectable
1om4B-4fnqA:
undetectable		 1om4A-4fnqA:
20.73
1om4B-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OXR_A_AINA141_1
(PHOSPHOLIPASE A2
ISOFORM 3)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 4 LEU A 119
GLY A 255
ASP A 534
TYR A 508
 None
 1.44A 1oxrA-4fnqA:
undetectable		 1oxrA-4fnqA:
9.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.48A 1p6hA-4fnqA:
undetectable
1p6hB-4fnqA:
undetectable		 1p6hA-4fnqA:
20.86
1p6hB-4fnqA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6I_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.47A 1p6iA-4fnqA:
undetectable
1p6iB-4fnqA:
undetectable		 1p6iA-4fnqA:
20.86
1p6iB-4fnqA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6I_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.48A 1p6iA-4fnqA:
undetectable
1p6iB-4fnqA:
undetectable		 1p6iA-4fnqA:
20.86
1p6iB-4fnqA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.45A 1p6kA-4fnqA:
undetectable
1p6kB-4fnqA:
undetectable		 1p6kA-4fnqA:
21.05
1p6kB-4fnqA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.45A 1p6kA-4fnqA:
undetectable
1p6kB-4fnqA:
undetectable		 1p6kA-4fnqA:
21.05
1p6kB-4fnqA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q13_A_TESA501_1
(PROSTAGLANDIN-E2
9-REDUCTASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 TYR A 503
GLU A 415
PRO A 414
VAL A 455
 None
 1.40A 1q13A-4fnqA:
7.4		 1q13A-4fnqA:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_A_DVAA8_0
(ACTINOMYCIN X2)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		3 / 3 THR A 187
THR A 268
PRO A 186
 None
 0.80A 1qfiA-4fnqA:
undetectable		 1qfiA-4fnqA:
1.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.46A 1rs6A-4fnqA:
undetectable
1rs6B-4fnqA:
undetectable		 1rs6A-4fnqA:
20.86
1rs6B-4fnqA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS6_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 8 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.49A 1rs6A-4fnqA:
undetectable
1rs6B-4fnqA:
undetectable		 1rs6A-4fnqA:
20.86
1rs6B-4fnqA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_A_DVAA6_0
(MINI-GRAMICIDIN A)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		3 / 3 ALA A  19
VAL A 158
TRP A 156
 None
 0.98A 1tkqA-4fnqA:
undetectable		 1tkqA-4fnqA:
2.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUB_B_TXLB501_1
(TUBULIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		5 / 12 VAL A  43
ASP A  42
LEU A  31
SER A  20
ARG A  15
 None
 1.38A 1tubB-4fnqA:
undetectable		 1tubB-4fnqA:
20.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TW4_A_CHDA130_1
(FATTY ACID-BINDING
PROTEIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		3 / 3 TYR A 150
ARG A 270
GLN A  74
 None
 0.91A 1tw4A-4fnqA:
undetectable		 1tw4A-4fnqA:
12.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF2_0
(7-AMINO-ACTINOMYCIN
D)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		3 / 3 THR A 268
PRO A 186
THR A 187
 None
 0.81A 1unjF-4fnqA:
undetectable		 1unjF-4fnqA:
1.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF8_0
(7-AMINO-ACTINOMYCIN
D)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		3 / 3 THR A 187
THR A 268
PRO A 186
 None
 0.82A 1unjF-4fnqA:
undetectable		 1unjF-4fnqA:
1.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		3 / 3 THR A 268
PRO A 186
THR A 187
 None
 0.84A 1unjL-4fnqA:
undetectable		 1unjL-4fnqA:
1.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		3 / 3 THR A 187
THR A 268
PRO A 186
 None
 0.80A 1unjL-4fnqA:
undetectable		 1unjL-4fnqA:
1.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		3 / 3 THR A 268
PRO A 186
THR A 187
 None
 0.77A 1unjR-4fnqA:
undetectable		 1unjR-4fnqA:
1.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		3 / 3 THR A 187
THR A 268
PRO A 186
 None
 0.77A 1unjR-4fnqA:
undetectable		 1unjR-4fnqA:
1.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_W_DVAW8_0
(7-AMINO-ACTINOMYCIN
D)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		3 / 3 THR A 187
THR A 268
PRO A 186
 None
 0.86A 1unjW-4fnqA:
undetectable		 1unjW-4fnqA:
1.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		3 / 3 THR A 268
PRO A 186
THR A 187
 None
 0.78A 1unjX-4fnqA:
undetectable		 1unjX-4fnqA:
1.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		3 / 3 THR A 187
THR A 268
PRO A 186
 None
 0.78A 1unjX-4fnqA:
undetectable		 1unjX-4fnqA:
1.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		3 / 3 THR A 268
PRO A 186
THR A 187
 None
 0.86A 1unmE-4fnqA:
undetectable		 1unmE-4fnqA:
1.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE8_0
(7-AMINOACTINOMYCIN D)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		3 / 3 THR A 187
THR A 268
PRO A 186
 None
 0.84A 1unmE-4fnqA:
undetectable		 1unmE-4fnqA:
1.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		3 / 3 THR A 268
PRO A 186
THR A 187
 None
 0.78A 1unmF-4fnqA:
undetectable		 1unmF-4fnqA:
1.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF8_0
(7-AMINOACTINOMYCIN D)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		3 / 3 THR A 187
THR A 268
PRO A 186
 None
 0.75A 1unmF-4fnqA:
undetectable		 1unmF-4fnqA:
1.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_A_NCTA1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 8 TYR A 153
THR A 317
TYR A 123
LEU A 538
 None
 1.45A 1uw6A-4fnqA:
undetectable
1uw6B-4fnqA:
undetectable		 1uw6A-4fnqA:
14.64
1uw6B-4fnqA:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_D_NCTD1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 8 TYR A 153
THR A 317
TYR A 123
LEU A 538
 None
 1.45A 1uw6D-4fnqA:
undetectable
1uw6E-4fnqA:
undetectable		 1uw6D-4fnqA:
14.64
1uw6E-4fnqA:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_T_NCTT1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 8 LEU A 538
TYR A 153
THR A 317
TYR A 123
 None
 1.46A 1uw6P-4fnqA:
undetectable
1uw6T-4fnqA:
undetectable		 1uw6P-4fnqA:
14.64
1uw6T-4fnqA:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_1
(VP39)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		3 / 3 ASP A  64
ARG A  27
ASP A  53
 None
 0.90A 1vptA-4fnqA:
undetectable		 1vptA-4fnqA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.47A 1zzqA-4fnqA:
undetectable
1zzqB-4fnqA:
undetectable		 1zzqA-4fnqA:
20.97
1zzqB-4fnqA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.44A 1zzqA-4fnqA:
undetectable
1zzqB-4fnqA:
undetectable		 1zzqA-4fnqA:
20.97
1zzqB-4fnqA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_D_SAMD301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		5 / 12 LEU A 119
GLY A 536
TYR A 253
ASP A 534
ARG A 532
 None
 0.97A 2br4D-4fnqA:
undetectable		 2br4D-4fnqA:
15.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_A_NCAA1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 SER A 525
PHE A 533
ARG A 203
GLU A 524
 None
 1.08A 2c8aA-4fnqA:
undetectable		 2c8aA-4fnqA:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_B_NCAB1246_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 GLY A 531
SER A 525
PHE A 533
GLU A 524
 None
 1.03A 2c8aB-4fnqA:
undetectable		 2c8aB-4fnqA:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_B_NCAB1246_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 SER A 525
PHE A 533
ARG A 203
GLU A 524
 None
 0.90A 2c8aB-4fnqA:
undetectable		 2c8aB-4fnqA:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_C_NCAC1252_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 SER A 525
PHE A 533
ARG A 203
GLU A 524
 None
 1.08A 2c8aC-4fnqA:
undetectable		 2c8aC-4fnqA:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_D_NCAD1247_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 SER A 525
PHE A 533
ARG A 203
GLU A 524
 None
 1.10A 2c8aD-4fnqA:
undetectable		 2c8aD-4fnqA:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 8 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.46A 2g6hA-4fnqA:
undetectable
2g6hB-4fnqA:
undetectable		 2g6hA-4fnqA:
20.78
2g6hB-4fnqA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.47A 2g6hA-4fnqA:
undetectable
2g6hB-4fnqA:
undetectable		 2g6hA-4fnqA:
20.78
2g6hB-4fnqA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 2g6kA-4fnqA:
undetectable
2g6kB-4fnqA:
undetectable		 2g6kA-4fnqA:
20.78
2g6kB-4fnqA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.47A 2g6kA-4fnqA:
undetectable
2g6kB-4fnqA:
undetectable		 2g6kA-4fnqA:
20.78
2g6kB-4fnqA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 2g6mA-4fnqA:
undetectable
2g6mB-4fnqA:
undetectable		 2g6mA-4fnqA:
20.78
2g6mB-4fnqA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.45A 2g6mA-4fnqA:
undetectable
2g6mB-4fnqA:
undetectable		 2g6mA-4fnqA:
20.78
2g6mB-4fnqA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX3_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.50A 2hx3A-4fnqA:
undetectable
2hx3B-4fnqA:
undetectable		 2hx3A-4fnqA:
20.73
2hx3B-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HX4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 2hx4A-4fnqA:
undetectable
2hx4B-4fnqA:
undetectable		 2hx4A-4fnqA:
20.73
2hx4B-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2I30_A_SALA1100_1
(SERUM ALBUMIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 PHE A 251
TYR A 508
ARG A 532
GLY A 255
 None
 1.32A 2i30A-4fnqA:
undetectable		 2i30A-4fnqA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WLK_B_SPMB1302_1
(ATP-SENSITIVE INWARD
RECTIFIER POTASSIUM
CHANNEL 10)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 4 ALA A 570
TYR A 566
ALA A 320
TYR A 315
 None
 1.32A 2wlkA-4fnqA:
undetectable
2wlkB-4fnqA:
undetectable		 2wlkA-4fnqA:
17.12
2wlkB-4fnqA:
17.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZB7_A_NCAA901_0
(PROSTAGLANDIN
REDUCTASE 2)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 5 TYR A 698
ILE A 692
LEU A 684
LEU A 681
 None
 1.05A 2zb7A-4fnqA:
undetectable		 2zb7A-4fnqA:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA607_1
(CHITINASE A)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A 296
SER A 250
THR A 122
LEU A 319
 None
 1.03A 3arrA-4fnqA:
4.7		 3arrA-4fnqA:
24.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.45A 3b3mA-4fnqA:
undetectable
3b3mB-4fnqA:
undetectable		 3b3mA-4fnqA:
20.73
3b3mB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3M_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.46A 3b3mA-4fnqA:
undetectable
3b3mB-4fnqA:
undetectable		 3b3mA-4fnqA:
20.73
3b3mB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.47A 3b3nA-4fnqA:
undetectable
3b3nB-4fnqA:
undetectable		 3b3nA-4fnqA:
20.73
3b3nB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 3b3oA-4fnqA:
undetectable
3b3oB-4fnqA:
undetectable		 3b3oA-4fnqA:
20.73
3b3oB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.45A 3b3pA-4fnqA:
undetectable
3b3pB-4fnqA:
undetectable		 3b3pA-4fnqA:
20.73
3b3pB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_B_CHDB500_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 THR A 151
VAL A 158
THR A 160
VAL A 296
 None
 0.55A 3em0B-4fnqA:
2.7		 3em0B-4fnqA:
11.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 3fc5A-4fnqA:
undetectable
3fc5B-4fnqA:
undetectable		 3fc5A-4fnqA:
20.73
3fc5B-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC5_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.48A 3fc5A-4fnqA:
undetectable
3fc5B-4fnqA:
undetectable		 3fc5A-4fnqA:
20.73
3fc5B-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FSU_A_C2FA995_0
(5,10-METHYLENETETRAH
YDROFOLATE REDUCTASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		5 / 12 THR A 292
LEU A 137
GLN A  74
THR A 100
LEU A 148
 None
 1.24A 3fsuA-4fnqA:
2.4		 3fsuA-4fnqA:
19.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GVU_A_STIA1001_2
(TYROSINE-PROTEIN
KINASE ABL2)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 5 VAL A 417
ILE A 459
TYR A 540
MET A 537
 None
 1.29A 3gvuA-4fnqA:
undetectable		 3gvuA-4fnqA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA424_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 8 PRO A 293
SER A 180
GLY A 536
PRO A 535
 None
 0.90A 3hcrA-4fnqA:
undetectable		 3hcrA-4fnqA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.44A 3hsnA-4fnqA:
undetectable
3hsnB-4fnqA:
undetectable		 3hsnA-4fnqA:
20.73
3hsnB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.45A 3hsnA-4fnqA:
undetectable
3hsnB-4fnqA:
undetectable		 3hsnA-4fnqA:
20.73
3hsnB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.47A 3hsoA-4fnqA:
undetectable
3hsoB-4fnqA:
undetectable		 3hsoA-4fnqA:
20.73
3hsoB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.45A 3hsoA-4fnqA:
undetectable
3hsoB-4fnqA:
undetectable		 3hsoA-4fnqA:
20.73
3hsoB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.45A 3hspA-4fnqA:
undetectable
3hspB-4fnqA:
undetectable		 3hspA-4fnqA:
20.73
3hspB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.49A 3hspA-4fnqA:
undetectable
3hspB-4fnqA:
undetectable		 3hspA-4fnqA:
20.73
3hspB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IIZ_A_SAMA1501_0
(BIOTIN SYNTHETASE,
PUTATIVE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		5 / 12 GLN A 543
ARG A 555
ILE A 360
TYR A 474
LEU A 332
 None
 1.23A 3iizA-4fnqA:
7.7		 3iizA-4fnqA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.44A 3jt3A-4fnqA:
undetectable
3jt3B-4fnqA:
undetectable		 3jt3A-4fnqA:
20.73
3jt3B-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.46A 3jt4A-4fnqA:
undetectable
3jt4B-4fnqA:
undetectable		 3jt4A-4fnqA:
20.73
3jt4B-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.45A 3jt4A-4fnqA:
undetectable
3jt4B-4fnqA:
undetectable		 3jt4A-4fnqA:
20.73
3jt4B-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.44A 3jt5A-4fnqA:
undetectable
3jt5B-4fnqA:
undetectable		 3jt5A-4fnqA:
20.73
3jt5B-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.48A 3jt5A-4fnqA:
undetectable
3jt5B-4fnqA:
undetectable		 3jt5A-4fnqA:
20.73
3jt5B-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.45A 3jt6A-4fnqA:
undetectable
3jt6B-4fnqA:
undetectable		 3jt6A-4fnqA:
20.73
3jt6B-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.44A 3jt7A-4fnqA:
undetectable
3jt7B-4fnqA:
undetectable		 3jt7A-4fnqA:
20.73
3jt7B-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.46A 3jt7A-4fnqA:
undetectable
3jt7B-4fnqA:
undetectable		 3jt7A-4fnqA:
20.73
3jt7B-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.47A 3jt8A-4fnqA:
undetectable
3jt8B-4fnqA:
undetectable		 3jt8A-4fnqA:
20.73
3jt8B-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.48A 3jt8A-4fnqA:
undetectable
3jt8B-4fnqA:
undetectable		 3jt8A-4fnqA:
20.73
3jt8B-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.44A 3jt9A-4fnqA:
undetectable
3jt9B-4fnqA:
undetectable		 3jt9A-4fnqA:
20.73
3jt9B-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.48A 3jt9A-4fnqA:
undetectable
3jt9B-4fnqA:
undetectable		 3jt9A-4fnqA:
20.73
3jt9B-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 3jtaA-4fnqA:
undetectable
3jtaB-4fnqA:
undetectable		 3jtaA-4fnqA:
20.73
3jtaB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.47A 3jwsA-4fnqA:
undetectable
3jwsB-4fnqA:
undetectable		 3jwsA-4fnqA:
20.38
3jwsB-4fnqA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWS_B_H4BB761_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.49A 3jwsA-4fnqA:
undetectable
3jwsB-4fnqA:
undetectable		 3jwsA-4fnqA:
20.38
3jwsB-4fnqA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 3jwtA-4fnqA:
undetectable
3jwtB-4fnqA:
undetectable		 3jwtA-4fnqA:
20.38
3jwtB-4fnqA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.47A 3jwtA-4fnqA:
undetectable
3jwtB-4fnqA:
undetectable		 3jwtA-4fnqA:
20.38
3jwtB-4fnqA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 3jwuA-4fnqA:
undetectable
3jwuB-4fnqA:
undetectable		 3jwuA-4fnqA:
20.38
3jwuB-4fnqA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.49A 3jwuA-4fnqA:
undetectable
3jwuB-4fnqA:
undetectable		 3jwuA-4fnqA:
20.38
3jwuB-4fnqA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.50A 3jwvA-4fnqA:
undetectable
3jwvB-4fnqA:
undetectable		 3jwvA-4fnqA:
20.38
3jwvB-4fnqA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.44A 3jx0A-4fnqA:
undetectable
3jx0B-4fnqA:
undetectable		 3jx0A-4fnqA:
20.92
3jx0B-4fnqA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.48A 3jx0A-4fnqA:
undetectable
3jx0B-4fnqA:
undetectable		 3jx0A-4fnqA:
20.92
3jx0B-4fnqA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.45A 3jx1A-4fnqA:
undetectable
3jx1B-4fnqA:
undetectable		 3jx1A-4fnqA:
20.92
3jx1B-4fnqA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K37_A_BCZA468_1
(NEURAMINIDASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		3 / 3 ASP A 184
ARG A  85
ARG A 161
 None
 0.98A 3k37A-4fnqA:
undetectable		 3k37A-4fnqA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.46A 3n2rA-4fnqA:
undetectable
3n2rB-4fnqA:
undetectable		 3n2rA-4fnqA:
20.73
3n2rB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.48A 3n2rA-4fnqA:
undetectable
3n2rB-4fnqA:
undetectable		 3n2rA-4fnqA:
20.73
3n2rB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 3n5yA-4fnqA:
undetectable
3n5yB-4fnqA:
undetectable		 3n5yA-4fnqA:
20.73
3n5yB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.49A 3n5yA-4fnqA:
undetectable
3n5yB-4fnqA:
undetectable		 3n5yA-4fnqA:
20.73
3n5yB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 3n5zA-4fnqA:
undetectable
3n5zB-4fnqA:
undetectable		 3n5zA-4fnqA:
20.73
3n5zB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.48A 3n5zA-4fnqA:
undetectable
3n5zB-4fnqA:
undetectable		 3n5zA-4fnqA:
20.73
3n5zB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NAI_C_URFC521_1
(RNA DEPENDENT RNA
POLYMERASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 5 ARG A 373
ASP A 366
ASP A 478
ARG A 443
 None
 1.46A 3naiC-4fnqA:
undetectable		 3naiC-4fnqA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.45A 3nlmA-4fnqA:
undetectable
3nlmB-4fnqA:
undetectable		 3nlmA-4fnqA:
20.73
3nlmB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.50A 3nlmA-4fnqA:
undetectable
3nlmB-4fnqA:
undetectable		 3nlmA-4fnqA:
20.73
3nlmB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.49A 3nlnA-4fnqA:
undetectable
3nlnB-4fnqA:
undetectable		 3nlnA-4fnqA:
20.38
3nlnB-4fnqA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.49A 3nloA-4fnqA:
undetectable
3nloB-4fnqA:
undetectable		 3nloA-4fnqA:
20.38
3nloB-4fnqA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.46A 3nlvA-4fnqA:
undetectable
3nlvB-4fnqA:
undetectable		 3nlvA-4fnqA:
20.73
3nlvB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.47A 3nlwA-4fnqA:
undetectable
3nlwB-4fnqA:
undetectable		 3nlwA-4fnqA:
20.73
3nlwB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.49A 3nlwA-4fnqA:
undetectable
3nlwB-4fnqA:
undetectable		 3nlwA-4fnqA:
20.73
3nlwB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.46A 3nlxA-4fnqA:
undetectable
3nlxB-4fnqA:
undetectable		 3nlxA-4fnqA:
20.73
3nlxB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.47A 3nlxA-4fnqA:
undetectable
3nlxB-4fnqA:
undetectable		 3nlxA-4fnqA:
20.73
3nlxB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 3nlyA-4fnqA:
undetectable
3nlyB-4fnqA:
undetectable		 3nlyA-4fnqA:
20.73
3nlyB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.44A 3nlzA-4fnqA:
undetectable
3nlzB-4fnqA:
undetectable		 3nlzA-4fnqA:
20.73
3nlzB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.48A 3nlzA-4fnqA:
undetectable
3nlzB-4fnqA:
undetectable		 3nlzA-4fnqA:
20.73
3nlzB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.46A 3nm0A-4fnqA:
undetectable
3nm0B-4fnqA:
undetectable		 3nm0A-4fnqA:
20.73
3nm0B-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.46A 3nm0A-4fnqA:
undetectable
3nm0B-4fnqA:
undetectable		 3nm0A-4fnqA:
20.73
3nm0B-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.46A 3nnyA-4fnqA:
undetectable
3nnyB-4fnqA:
undetectable		 3nnyA-4fnqA:
20.73
3nnyB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.48A 3nnyA-4fnqA:
undetectable
3nnyB-4fnqA:
undetectable		 3nnyA-4fnqA:
20.73
3nnyB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.46A 3nnzA-4fnqA:
undetectable
3nnzB-4fnqA:
undetectable		 3nnzA-4fnqA:
20.73
3nnzB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.48A 3nnzA-4fnqA:
undetectable
3nnzB-4fnqA:
undetectable		 3nnzA-4fnqA:
20.73
3nnzB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.44A 3pneA-4fnqA:
undetectable
3pneB-4fnqA:
undetectable		 3pneA-4fnqA:
20.73
3pneB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.47A 3pneA-4fnqA:
undetectable
3pneB-4fnqA:
undetectable		 3pneA-4fnqA:
20.73
3pneB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.47A 3pnfA-4fnqA:
undetectable
3pnfB-4fnqA:
undetectable		 3pnfA-4fnqA:
20.73
3pnfB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.48A 3pnfA-4fnqA:
undetectable
3pnfB-4fnqA:
undetectable		 3pnfA-4fnqA:
20.73
3pnfB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.43A 3pngA-4fnqA:
undetectable
3pngB-4fnqA:
undetectable		 3pngA-4fnqA:
20.73
3pngB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.48A 3pngA-4fnqA:
undetectable
3pngB-4fnqA:
undetectable		 3pngA-4fnqA:
20.73
3pngB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_B_STIB4_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 5 VAL A 455
ILE A 460
MET A 541
ARG A 502
 None
 1.29A 3pyyB-4fnqA:
undetectable		 3pyyB-4fnqA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.44A 3q99A-4fnqA:
undetectable
3q99B-4fnqA:
undetectable		 3q99A-4fnqA:
20.73
3q99B-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.48A 3q99A-4fnqA:
undetectable
3q99B-4fnqA:
undetectable		 3q99A-4fnqA:
20.73
3q99B-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.45A 3q9aA-4fnqA:
undetectable
3q9aB-4fnqA:
undetectable		 3q9aA-4fnqA:
20.73
3q9aB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.47A 3q9aA-4fnqA:
undetectable
3q9aB-4fnqA:
undetectable		 3q9aA-4fnqA:
20.73
3q9aB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.47A 3rqjA-4fnqA:
undetectable
3rqjB-4fnqA:
undetectable		 3rqjA-4fnqA:
20.73
3rqjB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.50A 3rqkA-4fnqA:
undetectable
3rqkB-4fnqA:
undetectable		 3rqkA-4fnqA:
20.73
3rqkB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.47A 3rqlA-4fnqA:
undetectable
3rqlB-4fnqA:
undetectable		 3rqlA-4fnqA:
20.73
3rqlB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.47A 3rqmA-4fnqA:
undetectable
3rqmB-4fnqA:
undetectable		 3rqmA-4fnqA:
20.73
3rqmB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.49A 3rqmA-4fnqA:
undetectable
3rqmB-4fnqA:
undetectable		 3rqmA-4fnqA:
20.73
3rqmB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.45A 3rqnA-4fnqA:
undetectable
3rqnB-4fnqA:
undetectable		 3rqnA-4fnqA:
20.73
3rqnB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.48A 3rqnA-4fnqA:
undetectable
3rqnB-4fnqA:
undetectable		 3rqnA-4fnqA:
20.73
3rqnB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.50A 3svqA-4fnqA:
undetectable
3svqB-4fnqA:
undetectable		 3svqA-4fnqA:
20.73
3svqB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 3tylA-4fnqA:
undetectable
3tylB-4fnqA:
undetectable		 3tylA-4fnqA:
20.73
3tylB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.49A 3tylA-4fnqA:
undetectable
3tylB-4fnqA:
undetectable		 3tylA-4fnqA:
20.73
3tylB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.47A 3tynA-4fnqA:
undetectable
3tynB-4fnqA:
undetectable		 3tynA-4fnqA:
20.73
3tynB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.49A 3tynA-4fnqA:
undetectable
3tynB-4fnqA:
undetectable		 3tynA-4fnqA:
20.73
3tynB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 3tyoA-4fnqA:
undetectable
3tyoB-4fnqA:
undetectable		 3tyoA-4fnqA:
20.73
3tyoB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.49A 3tyoA-4fnqA:
undetectable
3tyoB-4fnqA:
undetectable		 3tyoA-4fnqA:
20.73
3tyoB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.44A 3ufoA-4fnqA:
undetectable
3ufoB-4fnqA:
undetectable		 3ufoA-4fnqA:
20.73
3ufoB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.46A 3ufpA-4fnqA:
undetectable
3ufpB-4fnqA:
undetectable		 3ufpA-4fnqA:
20.73
3ufpB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 3ufqA-4fnqA:
undetectable
3ufqB-4fnqA:
undetectable		 3ufqA-4fnqA:
20.73
3ufqB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.50A 3ufqA-4fnqA:
undetectable
3ufqB-4fnqA:
undetectable		 3ufqA-4fnqA:
20.73
3ufqB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.41A 3ufrA-4fnqA:
undetectable
3ufrB-4fnqA:
undetectable		 3ufrA-4fnqA:
20.73
3ufrB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.49A 3ufrA-4fnqA:
undetectable
3ufrB-4fnqA:
undetectable		 3ufrA-4fnqA:
20.73
3ufrB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.47A 3ufsA-4fnqA:
undetectable
3ufsB-4fnqA:
undetectable		 3ufsA-4fnqA:
20.73
3ufsB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.48A 3ufsA-4fnqA:
undetectable
3ufsB-4fnqA:
undetectable		 3ufsA-4fnqA:
20.73
3ufsB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.49A 3ufuA-4fnqA:
undetectable
3ufuB-4fnqA:
undetectable		 3ufuA-4fnqA:
20.73
3ufuB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.49A 3ufuA-4fnqA:
undetectable
3ufuB-4fnqA:
undetectable		 3ufuA-4fnqA:
20.73
3ufuB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.49A 3ufvA-4fnqA:
undetectable
3ufvB-4fnqA:
undetectable		 3ufvA-4fnqA:
20.73
3ufvB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.49A 3ufvA-4fnqA:
undetectable
3ufvB-4fnqA:
undetectable		 3ufvA-4fnqA:
20.73
3ufvB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.49A 3ufwA-4fnqA:
undetectable
3ufwB-4fnqA:
undetectable		 3ufwA-4fnqA:
20.73
3ufwB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.49A 3ufwA-4fnqA:
undetectable
3ufwB-4fnqA:
undetectable		 3ufwA-4fnqA:
20.73
3ufwB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.46A 4c39A-4fnqA:
undetectable
4c39B-4fnqA:
undetectable		 4c39A-4fnqA:
20.73
4c39B-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.47A 4c39A-4fnqA:
undetectable
4c39B-4fnqA:
undetectable		 4c39A-4fnqA:
20.73
4c39B-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.44A 4camA-4fnqA:
undetectable
4camB-4fnqA:
undetectable		 4camA-4fnqA:
20.73
4camB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.46A 4camA-4fnqA:
undetectable
4camB-4fnqA:
undetectable		 4camA-4fnqA:
20.73
4camB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_A_ZMRA1471_2
(NEURAMINIDASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 5 LEU A 380
ASP A 376
ARG A 377
ARG A 373
 None
 1.42A 4cpzA-4fnqA:
undetectable		 4cpzA-4fnqA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.46A 4ctpA-4fnqA:
undetectable
4ctpB-4fnqA:
undetectable		 4ctpA-4fnqA:
20.73
4ctpB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.47A 4ctpA-4fnqA:
undetectable
4ctpB-4fnqA:
undetectable		 4ctpA-4fnqA:
20.73
4ctpB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.47A 4ctqA-4fnqA:
undetectable
4ctqB-4fnqA:
undetectable		 4ctqA-4fnqA:
20.73
4ctqB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.46A 4ctqA-4fnqA:
undetectable
4ctqB-4fnqA:
undetectable		 4ctqA-4fnqA:
20.73
4ctqB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.47A 4cttA-4fnqA:
undetectable
4cttB-4fnqA:
undetectable		 4cttA-4fnqA:
20.73
4cttB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 4ctuA-4fnqA:
undetectable
4ctuB-4fnqA:
undetectable		 4ctuA-4fnqA:
20.73
4ctuB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.50A 4ctuA-4fnqA:
undetectable
4ctuB-4fnqA:
undetectable		 4ctuA-4fnqA:
20.73
4ctuB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.47A 4ctvA-4fnqA:
undetectable
4ctvB-4fnqA:
undetectable		 4ctvA-4fnqA:
20.73
4ctvB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTV_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.47A 4ctvA-4fnqA:
undetectable
4ctvB-4fnqA:
undetectable		 4ctvA-4fnqA:
20.73
4ctvB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.46A 4ctwA-4fnqA:
undetectable
4ctwB-4fnqA:
undetectable		 4ctwA-4fnqA:
20.73
4ctwB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_B_H4BB1720_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.47A 4ctwA-4fnqA:
undetectable
4ctwB-4fnqA:
undetectable		 4ctwA-4fnqA:
20.73
4ctwB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.47A 4ctxA-4fnqA:
undetectable
4ctxB-4fnqA:
undetectable		 4ctxA-4fnqA:
20.73
4ctxB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.46A 4ctxA-4fnqA:
undetectable
4ctxB-4fnqA:
undetectable		 4ctxA-4fnqA:
20.73
4ctxB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.46A 4cx5A-4fnqA:
undetectable
4cx5B-4fnqA:
undetectable		 4cx5A-4fnqA:
20.86
4cx5B-4fnqA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.47A 4cx5A-4fnqA:
undetectable
4cx5B-4fnqA:
undetectable		 4cx5A-4fnqA:
20.86
4cx5B-4fnqA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.46A 4cx6A-4fnqA:
undetectable
4cx6B-4fnqA:
undetectable		 4cx6A-4fnqA:
20.86
4cx6B-4fnqA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.49A 4cx6A-4fnqA:
undetectable
4cx6B-4fnqA:
undetectable		 4cx6A-4fnqA:
20.86
4cx6B-4fnqA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.43A 4d1nA-4fnqA:
undetectable
4d1nB-4fnqA:
undetectable		 4d1nA-4fnqA:
20.60
4d1nB-4fnqA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.43A 4d1nA-4fnqA:
undetectable
4d1nB-4fnqA:
undetectable		 4d1nA-4fnqA:
20.60
4d1nB-4fnqA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.43A 4d1nC-4fnqA:
undetectable
4d1nD-4fnqA:
undetectable		 4d1nC-4fnqA:
20.60
4d1nD-4fnqA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.43A 4d1nC-4fnqA:
undetectable
4d1nD-4fnqA:
undetectable		 4d1nC-4fnqA:
20.60
4d1nD-4fnqA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.49A 4d2yA-4fnqA:
undetectable
4d2yB-4fnqA:
undetectable		 4d2yA-4fnqA:
20.73
4d2yB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.50A 4d2yA-4fnqA:
undetectable
4d2yB-4fnqA:
undetectable		 4d2yA-4fnqA:
20.73
4d2yB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D32_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.49A 4d32A-4fnqA:
undetectable
4d32B-4fnqA:
undetectable		 4d32A-4fnqA:
20.73
4d32B-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.45A 4d3bA-4fnqA:
undetectable
4d3bB-4fnqA:
undetectable		 4d3bA-4fnqA:
20.73
4d3bB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.49A 4d3bA-4fnqA:
undetectable
4d3bB-4fnqA:
undetectable		 4d3bA-4fnqA:
20.73
4d3bB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7H_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		3 / 3 ARG A 316
THR A 310
TRP A 156
 None
 1.24A 4d7hA-4fnqA:
undetectable		 4d7hA-4fnqA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.46A 4d7oA-4fnqA:
undetectable
4d7oB-4fnqA:
undetectable		 4d7oA-4fnqA:
20.73
4d7oB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.48A 4d7oA-4fnqA:
undetectable
4d7oB-4fnqA:
undetectable		 4d7oA-4fnqA:
20.73
4d7oB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EB4_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		5 / 10 ILE A 459
ASP A 382
LEU A 423
GLY A 381
LYS A 426
 None
 1.41A 4eb4D-4fnqA:
undetectable		 4eb4D-4fnqA:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_B_NCTB501_1
(CYTOCHROME P450 2A13)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 8 PHE A 343
ASN A 335
LEU A 394
LEU A 397
 None
 0.93A 4ejgB-4fnqA:
undetectable		 4ejgB-4fnqA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EJG_C_NCTC501_1
(CYTOCHROME P450 2A13)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 PHE A 343
ASN A 335
LEU A 394
LEU A 397
 None
 0.91A 4ejgC-4fnqA:
undetectable		 4ejgC-4fnqA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.46A 4euxA-4fnqA:
undetectable
4euxB-4fnqA:
undetectable		 4euxA-4fnqA:
20.73
4euxB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.49A 4euxA-4fnqA:
undetectable
4euxB-4fnqA:
undetectable		 4euxA-4fnqA:
20.73
4euxB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.45A 4fvwA-4fnqA:
undetectable
4fvwB-4fnqA:
undetectable		 4fvwA-4fnqA:
20.73
4fvwB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.47A 4fvwA-4fnqA:
undetectable
4fvwB-4fnqA:
undetectable		 4fvwA-4fnqA:
20.73
4fvwB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 4fvxA-4fnqA:
undetectable
4fvxB-4fnqA:
undetectable		 4fvxA-4fnqA:
20.73
4fvxB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.46A 4fvxA-4fnqA:
undetectable
4fvxB-4fnqA:
undetectable		 4fvxA-4fnqA:
20.73
4fvxB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.46A 4fvyA-4fnqA:
undetectable
4fvyB-4fnqA:
undetectable		 4fvyA-4fnqA:
20.73
4fvyB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.45A 4fvyA-4fnqA:
undetectable
4fvyB-4fnqA:
undetectable		 4fvyA-4fnqA:
20.73
4fvyB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.46A 4fvzA-4fnqA:
undetectable
4fvzB-4fnqA:
undetectable		 4fvzA-4fnqA:
20.73
4fvzB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.47A 4fvzA-4fnqA:
undetectable
4fvzB-4fnqA:
undetectable		 4fvzA-4fnqA:
20.73
4fvzB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.46A 4fw0A-4fnqA:
undetectable
4fw0B-4fnqA:
undetectable		 4fw0A-4fnqA:
20.73
4fw0B-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.46A 4fw0A-4fnqA:
undetectable
4fw0B-4fnqA:
undetectable		 4fw0A-4fnqA:
20.73
4fw0B-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_1
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		3 / 3 ASP A  64
ARG A  27
ASP A  53
 None
 0.87A 4fzvA-4fnqA:
undetectable		 4fzvA-4fnqA:
18.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.47A 4gqeA-4fnqA:
undetectable
4gqeB-4fnqA:
undetectable		 4gqeA-4fnqA:
20.73
4gqeB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.47A 4gqeA-4fnqA:
undetectable
4gqeB-4fnqA:
undetectable		 4gqeA-4fnqA:
20.73
4gqeB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HIV_D_DVAD2_0
(ACTINOMYCIN D)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		3 / 3 THR A 268
PRO A 186
THR A 187
 None
 0.87A 4hivD-4fnqA:
undetectable		 4hivD-4fnqA:
1.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.50A 4imtA-4fnqA:
undetectable
4imtB-4fnqA:
undetectable		 4imtA-4fnqA:
20.73
4imtB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.49A 4imwA-4fnqA:
undetectable
4imwB-4fnqA:
undetectable		 4imwA-4fnqA:
20.73
4imwB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 4jsgA-4fnqA:
undetectable
4jsgB-4fnqA:
undetectable		 4jsgA-4fnqA:
20.73
4jsgB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSG_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.49A 4jsgA-4fnqA:
undetectable
4jsgB-4fnqA:
undetectable		 4jsgA-4fnqA:
20.73
4jsgB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.49A 4jsiA-4fnqA:
undetectable
4jsiB-4fnqA:
undetectable		 4jsiA-4fnqA:
20.73
4jsiB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.50A 4jsiA-4fnqA:
undetectable
4jsiB-4fnqA:
undetectable		 4jsiA-4fnqA:
20.73
4jsiB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.47A 4jsjA-4fnqA:
undetectable
4jsjB-4fnqA:
undetectable		 4jsjA-4fnqA:
20.73
4jsjB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.49A 4jsjA-4fnqA:
undetectable
4jsjB-4fnqA:
undetectable		 4jsjA-4fnqA:
20.73
4jsjB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JXC_A_SAMA402_0
(FEFE-HYDROGENASE
MATURASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		5 / 12 GLN A 543
ARG A 555
ILE A 360
TYR A 474
LEU A 332
 None
 1.23A 4jxcA-4fnqA:
4.0		 4jxcA-4fnqA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.47A 4k5dA-4fnqA:
undetectable
4k5dB-4fnqA:
undetectable		 4k5dA-4fnqA:
20.73
4k5dB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.48A 4k5dA-4fnqA:
undetectable
4k5dB-4fnqA:
undetectable		 4k5dA-4fnqA:
20.73
4k5dB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.46A 4k5eA-4fnqA:
undetectable
4k5eB-4fnqA:
undetectable		 4k5eA-4fnqA:
20.73
4k5eB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.48A 4k5eA-4fnqA:
undetectable
4k5eB-4fnqA:
undetectable		 4k5eA-4fnqA:
20.73
4k5eB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.45A 4k5gA-4fnqA:
undetectable
4k5gB-4fnqA:
undetectable		 4k5gA-4fnqA:
20.73
4k5gB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.48A 4k5gA-4fnqA:
undetectable
4k5gB-4fnqA:
undetectable		 4k5gA-4fnqA:
20.73
4k5gB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.47A 4kcjA-4fnqA:
undetectable
4kcjB-4fnqA:
undetectable		 4kcjA-4fnqA:
20.73
4kcjB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCJ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.48A 4kcjA-4fnqA:
undetectable
4kcjB-4fnqA:
undetectable		 4kcjA-4fnqA:
20.73
4kcjB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.48A 4kcmA-4fnqA:
undetectable
4kcmB-4fnqA:
undetectable		 4kcmA-4fnqA:
20.73
4kcmB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 4kcnA-4fnqA:
undetectable
4kcnB-4fnqA:
undetectable		 4kcnA-4fnqA:
20.73
4kcnB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.48A 4kcnA-4fnqA:
undetectable
4kcnB-4fnqA:
undetectable		 4kcnA-4fnqA:
20.73
4kcnB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.45A 4kcoA-4fnqA:
undetectable
4kcoB-4fnqA:
undetectable		 4kcoA-4fnqA:
20.73
4kcoB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.47A 4kcoA-4fnqA:
undetectable
4kcoB-4fnqA:
undetectable		 4kcoA-4fnqA:
20.73
4kcoB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.46A 4luxA-4fnqA:
undetectable
4luxB-4fnqA:
undetectable		 4luxA-4fnqA:
20.73
4luxB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.47A 4luxA-4fnqA:
undetectable
4luxB-4fnqA:
undetectable		 4luxA-4fnqA:
20.73
4luxB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NTX_A_AMRA509_1
(ACID-SENSING ION
CHANNEL 1
BASIC PHOSPHOLIPASE
A2 HOMOLOG TX-BETA)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 GLU A 604
ASP A 367
ASN A 480
ARG A 443
 None
 1.33A 4ntxA-4fnqA:
undetectable
4ntxC-4fnqA:
undetectable		 4ntxA-4fnqA:
21.14
4ntxC-4fnqA:
9.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_G_377G401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 ARG A 481
GLU A 415
TYR A 503
LEU A 432
 None
 1.39A 4twdF-4fnqA:
undetectable
4twdG-4fnqA:
undetectable		 4twdF-4fnqA:
19.48
4twdG-4fnqA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 4uchA-4fnqA:
undetectable
4uchB-4fnqA:
undetectable		 4uchA-4fnqA:
20.43
4uchB-4fnqA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 8 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.48A 4uchA-4fnqA:
undetectable
4uchB-4fnqA:
undetectable		 4uchA-4fnqA:
20.43
4uchB-4fnqA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		5 / 12 GLY A 531
GLU A 202
GLY A 529
ASN A 549
ALA A 223
 None
 0.97A 4uciA-4fnqA:
undetectable		 4uciA-4fnqA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		5 / 12 GLY A 531
GLU A 202
GLY A 529
ASN A 549
ALA A 223
 None
 0.98A 4uciB-4fnqA:
undetectable		 4uciB-4fnqA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UG5_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		3 / 3 ARG A 316
THR A 310
TRP A 156
 None
 1.15A 4ug5A-4fnqA:
undetectable		 4ug5A-4fnqA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGL_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		3 / 3 ARG A 316
THR A 310
TRP A 156
 None
 1.24A 4uglA-4fnqA:
undetectable		 4uglA-4fnqA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UGZ_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.50A 4ugzA-4fnqA:
undetectable
4ugzB-4fnqA:
undetectable		 4ugzA-4fnqA:
20.73
4ugzB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.46A 4uh1A-4fnqA:
undetectable
4uh1B-4fnqA:
undetectable		 4uh1A-4fnqA:
20.73
4uh1B-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 4uh2A-4fnqA:
undetectable
4uh2B-4fnqA:
undetectable		 4uh2A-4fnqA:
20.73
4uh2B-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH2_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.49A 4uh2A-4fnqA:
undetectable
4uh2B-4fnqA:
undetectable		 4uh2A-4fnqA:
20.73
4uh2B-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH3_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.47A 4uh3A-4fnqA:
undetectable
4uh3B-4fnqA:
undetectable		 4uh3A-4fnqA:
20.73
4uh3B-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 4uh4A-4fnqA:
undetectable
4uh4B-4fnqA:
undetectable		 4uh4A-4fnqA:
20.73
4uh4B-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.48A 4uh4A-4fnqA:
undetectable
4uh4B-4fnqA:
undetectable		 4uh4A-4fnqA:
20.73
4uh4B-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 4uh5A-4fnqA:
undetectable
4uh5B-4fnqA:
undetectable		 4uh5A-4fnqA:
20.57
4uh5B-4fnqA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.50A 4uh5A-4fnqA:
undetectable
4uh5B-4fnqA:
undetectable		 4uh5A-4fnqA:
20.57
4uh5B-4fnqA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 4uh6A-4fnqA:
undetectable
4uh6B-4fnqA:
undetectable		 4uh6A-4fnqA:
20.57
4uh6B-4fnqA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.49A 4uh6A-4fnqA:
undetectable
4uh6B-4fnqA:
undetectable		 4uh6A-4fnqA:
20.57
4uh6B-4fnqA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.47A 4upmA-4fnqA:
undetectable
4upmB-4fnqA:
undetectable		 4upmA-4fnqA:
20.73
4upmB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.49A 4upmA-4fnqA:
undetectable
4upmB-4fnqA:
undetectable		 4upmA-4fnqA:
20.73
4upmB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.44A 4upoA-4fnqA:
undetectable
4upoB-4fnqA:
undetectable		 4upoA-4fnqA:
20.73
4upoB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.49A 4upoA-4fnqA:
undetectable
4upoB-4fnqA:
undetectable		 4upoA-4fnqA:
20.73
4upoB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.44A 4uppA-4fnqA:
undetectable
4uppB-4fnqA:
undetectable		 4uppA-4fnqA:
20.73
4uppB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.49A 4uppA-4fnqA:
undetectable
4uppB-4fnqA:
undetectable		 4uppA-4fnqA:
20.73
4uppB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.46A 4v3uA-4fnqA:
undetectable
4v3uB-4fnqA:
undetectable		 4v3uA-4fnqA:
20.60
4v3uB-4fnqA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.44A 4v3uC-4fnqA:
undetectable
4v3uD-4fnqA:
undetectable		 4v3uC-4fnqA:
20.60
4v3uD-4fnqA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.50A 4v3uC-4fnqA:
undetectable
4v3uD-4fnqA:
undetectable		 4v3uC-4fnqA:
20.60
4v3uD-4fnqA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3V_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 4v3vA-4fnqA:
undetectable
4v3vB-4fnqA:
undetectable		 4v3vA-4fnqA:
20.73
4v3vB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.49A 4v3yA-4fnqA:
undetectable
4v3yB-4fnqA:
undetectable		 4v3yA-4fnqA:
20.73
4v3yB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZGF_A_BEZA210_0
(UNCHARACTERIZED
PROTEIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 4 VAL A 235
ALA A 239
ASN A 238
GLN A 243
 None
 1.48A 4zgfA-4fnqA:
undetectable		 4zgfA-4fnqA:
11.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AD8_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.50A 5ad8A-4fnqA:
0.0
5ad8B-4fnqA:
0.0		 5ad8A-4fnqA:
20.73
5ad8B-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADC_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 5adcA-4fnqA:
undetectable
5adcB-4fnqA:
undetectable		 5adcA-4fnqA:
20.73
5adcB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADD_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.46A 5addA-4fnqA:
undetectable
5addB-4fnqA:
undetectable		 5addA-4fnqA:
21.05
5addB-4fnqA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADF_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.48A 5adfA-4fnqA:
0.0
5adfB-4fnqA:
0.0		 5adfA-4fnqA:
20.57
5adfB-4fnqA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.49A 5adgA-4fnqA:
undetectable
5adgB-4fnqA:
undetectable		 5adgA-4fnqA:
20.57
5adgB-4fnqA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.48A 5adgA-4fnqA:
undetectable
5adgB-4fnqA:
undetectable		 5adgA-4fnqA:
20.57
5adgB-4fnqA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.50A 5agkA-4fnqA:
undetectable
5agkB-4fnqA:
undetectable		 5agkA-4fnqA:
20.73
5agkB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.47A 5aglA-4fnqA:
undetectable
5aglB-4fnqA:
undetectable		 5aglA-4fnqA:
20.73
5aglB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.48A 5aglA-4fnqA:
undetectable
5aglB-4fnqA:
undetectable		 5aglA-4fnqA:
20.73
5aglB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.46A 5agmA-4fnqA:
undetectable
5agmB-4fnqA:
undetectable		 5agmA-4fnqA:
20.73
5agmB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.46A 5agmA-4fnqA:
undetectable
5agmB-4fnqA:
undetectable		 5agmA-4fnqA:
20.73
5agmB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.44A 5agnA-4fnqA:
undetectable
5agnB-4fnqA:
undetectable		 5agnA-4fnqA:
20.73
5agnB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.47A 5agnA-4fnqA:
undetectable
5agnB-4fnqA:
undetectable		 5agnA-4fnqA:
20.73
5agnB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.47A 5agoA-4fnqA:
undetectable
5agoB-4fnqA:
undetectable		 5agoA-4fnqA:
20.73
5agoB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.49A 5agoA-4fnqA:
undetectable
5agoB-4fnqA:
undetectable		 5agoA-4fnqA:
20.73
5agoB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 5agpA-4fnqA:
undetectable
5agpB-4fnqA:
undetectable		 5agpA-4fnqA:
20.73
5agpB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.45A 5fvqA-4fnqA:
undetectable
5fvqB-4fnqA:
undetectable		 5fvqA-4fnqA:
20.73
5fvqB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVQ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.47A 5fvqA-4fnqA:
undetectable
5fvqB-4fnqA:
undetectable		 5fvqA-4fnqA:
20.73
5fvqB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.46A 5fvrA-4fnqA:
undetectable
5fvrB-4fnqA:
undetectable		 5fvrA-4fnqA:
20.73
5fvrB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.46A 5fvrA-4fnqA:
undetectable
5fvrB-4fnqA:
undetectable		 5fvrA-4fnqA:
20.73
5fvrB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 5fvsA-4fnqA:
undetectable
5fvsB-4fnqA:
undetectable		 5fvsA-4fnqA:
20.73
5fvsB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVS_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.47A 5fvsA-4fnqA:
undetectable
5fvsB-4fnqA:
undetectable		 5fvsA-4fnqA:
20.73
5fvsB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.45A 5fvtA-4fnqA:
undetectable
5fvtB-4fnqA:
undetectable		 5fvtA-4fnqA:
20.73
5fvtB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.47A 5fvtA-4fnqA:
undetectable
5fvtB-4fnqA:
undetectable		 5fvtA-4fnqA:
20.73
5fvtB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.43A 5fvuA-4fnqA:
undetectable
5fvuB-4fnqA:
undetectable		 5fvuA-4fnqA:
20.57
5fvuB-4fnqA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.49A 5fvvA-4fnqA:
undetectable
5fvvB-4fnqA:
undetectable		 5fvvA-4fnqA:
20.57
5fvvB-4fnqA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 5fvwA-4fnqA:
undetectable
5fvwB-4fnqA:
undetectable		 5fvwA-4fnqA:
20.57
5fvwB-4fnqA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.49A 5fvwA-4fnqA:
undetectable
5fvwB-4fnqA:
undetectable		 5fvwA-4fnqA:
20.57
5fvwB-4fnqA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.47A 5fvxA-4fnqA:
undetectable
5fvxB-4fnqA:
undetectable		 5fvxA-4fnqA:
20.57
5fvxB-4fnqA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.46A 5fw0A-4fnqA:
undetectable
5fw0B-4fnqA:
undetectable		 5fw0A-4fnqA:
20.73
5fw0B-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.50A 5fw0A-4fnqA:
undetectable
5fw0B-4fnqA:
undetectable		 5fw0A-4fnqA:
20.73
5fw0B-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.49A 5g0nA-4fnqA:
undetectable
5g0nB-4fnqA:
undetectable		 5g0nA-4fnqA:
20.92
5g0nB-4fnqA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.48A 5g0nA-4fnqA:
undetectable
5g0nB-4fnqA:
undetectable		 5g0nA-4fnqA:
20.92
5g0nB-4fnqA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.50A 5g0oA-4fnqA:
undetectable
5g0oB-4fnqA:
undetectable		 5g0oA-4fnqA:
20.92
5g0oB-4fnqA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G0O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.49A 5g0oA-4fnqA:
undetectable
5g0oB-4fnqA:
undetectable		 5g0oA-4fnqA:
20.92
5g0oB-4fnqA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6C_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE OXYGENASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		3 / 3 ARG A 316
THR A 310
TRP A 156
 None
 1.20A 5g6cA-4fnqA:
undetectable		 5g6cA-4fnqA:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_H_FK5H201_1
(FK506-BINDING
PROTEIN 1)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 8 ASP A 382
VAL A 455
ILE A 459
ILE A 384
 None
 0.71A 5hw8H-4fnqA:
undetectable		 5hw8H-4fnqA:
10.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKQ_A_JMSA602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		3 / 3 VAL A 434
SER A 440
MET A 416
 None
 0.94A 5ikqA-4fnqA:
undetectable		 5ikqA-4fnqA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZY_A_CE3A1102_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 203
GLN A 559
ILE A 558
GLY A 561
 None
 1.01A 5nzyA-4fnqA:
undetectable		 5nzyA-4fnqA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_B_SAMB201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		5 / 10 ILE A 558
GLY A 599
GLY A 572
LEU A 556
SER A 554
 None
 1.15A 5twjB-4fnqA:
undetectable		 5twjB-4fnqA:
11.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNR_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.46A 5unrA-4fnqA:
0.0
5unrB-4fnqA:
0.0		 5unrA-4fnqA:
20.73
5unrB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.49A 5unsA-4fnqA:
undetectable
5unsB-4fnqA:
undetectable		 5unsA-4fnqA:
20.73
5unsB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.49A 5unuA-4fnqA:
undetectable
5unuB-4fnqA:
undetectable		 5unuA-4fnqA:
20.73
5unuB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.49A 5unyA-4fnqA:
undetectable
5unyB-4fnqA:
undetectable		 5unyA-4fnqA:
20.73
5unyB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.50A 5uo1A-4fnqA:
undetectable
5uo1B-4fnqA:
undetectable		 5uo1A-4fnqA:
20.57
5uo1B-4fnqA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.47A 5uo1A-4fnqA:
undetectable
5uo1B-4fnqA:
undetectable		 5uo1A-4fnqA:
20.57
5uo1B-4fnqA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.50A 5uo4A-4fnqA:
undetectable
5uo4B-4fnqA:
undetectable		 5uo4A-4fnqA:
20.57
5uo4B-4fnqA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.48A 5uo4A-4fnqA:
undetectable
5uo4B-4fnqA:
undetectable		 5uo4A-4fnqA:
20.57
5uo4B-4fnqA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.46A 5uo5A-4fnqA:
undetectable
5uo5B-4fnqA:
undetectable		 5uo5A-4fnqA:
20.57
5uo5B-4fnqA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		5 / 12 GLY A 396
VAL A 412
VAL A 475
GLY A 409
ILE A 472
 None
 1.01A 5vopA-4fnqA:
7.7		 5vopA-4fnqA:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUI_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.50A 5vuiA-4fnqA:
undetectable
5vuiB-4fnqA:
undetectable		 5vuiA-4fnqA:
20.73
5vuiB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.46A 5vulA-4fnqA:
undetectable
5vulB-4fnqA:
undetectable		 5vulA-4fnqA:
20.73
5vulB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUL_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.49A 5vulA-4fnqA:
undetectable
5vulB-4fnqA:
undetectable		 5vulA-4fnqA:
20.73
5vulB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.46A 5vumA-4fnqA:
undetectable
5vumB-4fnqA:
undetectable		 5vumA-4fnqA:
20.73
5vumB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUM_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.48A 5vumA-4fnqA:
undetectable
5vumB-4fnqA:
undetectable		 5vumA-4fnqA:
20.73
5vumB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 5vunA-4fnqA:
undetectable
5vunB-4fnqA:
undetectable		 5vunA-4fnqA:
20.73
5vunB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 5vuoA-4fnqA:
undetectable
5vuoB-4fnqA:
undetectable		 5vuoA-4fnqA:
20.73
5vuoB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 5vupA-4fnqA:
undetectable
5vupB-4fnqA:
undetectable		 5vupA-4fnqA:
20.73
5vupB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUP_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.48A 5vupA-4fnqA:
undetectable
5vupB-4fnqA:
undetectable		 5vupA-4fnqA:
20.73
5vupB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.49A 5vuqA-4fnqA:
undetectable
5vuqB-4fnqA:
undetectable		 5vuqA-4fnqA:
20.73
5vuqB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 5vusA-4fnqA:
undetectable
5vusB-4fnqA:
undetectable		 5vusA-4fnqA:
20.73
5vusB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 5vutA-4fnqA:
undetectable
5vutB-4fnqA:
undetectable		 5vutA-4fnqA:
20.73
5vutB-4fnqA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.47A 5vuvA-4fnqA:
undetectable
5vuvB-4fnqA:
undetectable		 5vuvA-4fnqA:
20.57
5vuvB-4fnqA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.47A 5vuvA-4fnqA:
undetectable
5vuvB-4fnqA:
undetectable		 5vuvA-4fnqA:
20.57
5vuvB-4fnqA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.46A 5vuwA-4fnqA:
undetectable
5vuwB-4fnqA:
undetectable		 5vuwA-4fnqA:
20.57
5vuwB-4fnqA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.47A 5vuwA-4fnqA:
undetectable
5vuwB-4fnqA:
undetectable		 5vuwA-4fnqA:
20.57
5vuwB-4fnqA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 5vuxA-4fnqA:
undetectable
5vuxB-4fnqA:
undetectable		 5vuxA-4fnqA:
20.57
5vuxB-4fnqA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.48A 5vuxA-4fnqA:
0.0
5vuxB-4fnqA:
0.0		 5vuxA-4fnqA:
20.57
5vuxB-4fnqA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.46A 5vuyA-4fnqA:
undetectable
5vuyB-4fnqA:
undetectable		 5vuyA-4fnqA:
20.57
5vuyB-4fnqA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.46A 5vuzA-4fnqA:
undetectable
5vuzB-4fnqA:
undetectable		 5vuzA-4fnqA:
20.57
5vuzB-4fnqA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.48A 5vuzA-4fnqA:
undetectable
5vuzB-4fnqA:
undetectable		 5vuzA-4fnqA:
20.57
5vuzB-4fnqA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 5vv0A-4fnqA:
undetectable
5vv0B-4fnqA:
undetectable		 5vv0A-4fnqA:
20.57
5vv0B-4fnqA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV1_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.49A 5vv1A-4fnqA:
undetectable
5vv1B-4fnqA:
undetectable		 5vv1A-4fnqA:
20.57
5vv1B-4fnqA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV1_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.49A 5vv1A-4fnqA:
undetectable
5vv1B-4fnqA:
undetectable		 5vv1A-4fnqA:
20.57
5vv1B-4fnqA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.50A 5vv2A-4fnqA:
undetectable
5vv2B-4fnqA:
undetectable		 5vv2A-4fnqA:
20.57
5vv2B-4fnqA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 5vv4A-4fnqA:
undetectable
5vv4B-4fnqA:
undetectable		 5vv4A-4fnqA:
20.57
5vv4B-4fnqA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.47A 5vv4A-4fnqA:
undetectable
5vv4B-4fnqA:
undetectable		 5vv4A-4fnqA:
20.57
5vv4B-4fnqA:
20.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_E_D16E402_1
(THYMIDYLATE SYNTHASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 ILE A 459
ASP A 382
LEU A 423
GLY A 381
 None
 0.99A 5x5qE-4fnqA:
undetectable		 5x5qE-4fnqA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_C_SALC201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 VAL A 271
VAL A 295
GLY A 248
TYR A 247
 None
 0.92A 5x80C-4fnqA:
undetectable
5x80D-4fnqA:
undetectable		 5x80C-4fnqA:
12.95
5x80D-4fnqA:
12.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 GLN A 400
PHE A 408
LEU A 365
PHE A 343
 None
 1.12A 5z84P-4fnqA:
undetectable
5z84W-4fnqA:
undetectable		 5z84P-4fnqA:
18.23
5z84W-4fnqA:
6.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 GLN A 400
PHE A 408
LEU A 365
PHE A 343
 None
 1.10A 5z86P-4fnqA:
undetectable
5z86W-4fnqA:
undetectable		 5z86P-4fnqA:
18.23
5z86W-4fnqA:
6.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 GLN A 400
PHE A 408
LEU A 365
PHE A 343
 None
 1.10A 5zcoP-4fnqA:
undetectable
5zcoW-4fnqA:
undetectable		 5zcoP-4fnqA:
18.23
5zcoW-4fnqA:
6.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 GLN A 400
PHE A 408
LEU A 365
PHE A 343
 None
 1.11A 5zcpC-4fnqA:
undetectable
5zcpJ-4fnqA:
undetectable		 5zcpC-4fnqA:
18.23
5zcpJ-4fnqA:
6.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 GLN A 400
PHE A 408
LEU A 365
PHE A 343
 None
 1.12A 5zcpP-4fnqA:
undetectable
5zcpW-4fnqA:
undetectable		 5zcpP-4fnqA:
18.23
5zcpW-4fnqA:
6.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_0
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		5 / 12 ALA A 587
PRO A 579
SER A 576
ALA A 591
PHE A 717
 None
 1.13A 5zvgA-4fnqA:
undetectable		 5zvgA-4fnqA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_0
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		5 / 12 ALA A 587
PRO A 579
SER A 576
ALA A 591
PHE A 717
 None
 1.12A 5zvgB-4fnqA:
undetectable		 5zvgB-4fnqA:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUQ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.50A 6auqA-4fnqA:
undetectable
6auqB-4fnqA:
undetectable		 6auqA-4fnqA:
7.85
6auqB-4fnqA:
7.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.47A 6aurA-4fnqA:
undetectable
6aurB-4fnqA:
undetectable		 6aurA-4fnqA:
7.85
6aurB-4fnqA:
7.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUR_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.48A 6aurA-4fnqA:
undetectable
6aurB-4fnqA:
undetectable		 6aurA-4fnqA:
7.85
6aurB-4fnqA:
7.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 6ausA-4fnqA:
undetectable
6ausB-4fnqA:
undetectable		 6ausA-4fnqA:
7.85
6ausB-4fnqA:
7.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.49A 6ausA-4fnqA:
undetectable
6ausB-4fnqA:
undetectable		 6ausA-4fnqA:
7.85
6ausB-4fnqA:
7.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.49A 6autA-4fnqA:
undetectable
6autB-4fnqA:
undetectable		 6autA-4fnqA:
7.85
6autB-4fnqA:
7.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.49A 6auuA-4fnqA:
undetectable
6auuB-4fnqA:
undetectable		 6auuA-4fnqA:
7.85
6auuB-4fnqA:
7.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.47A 6auvA-4fnqA:
undetectable
6auvB-4fnqA:
undetectable		 6auvA-4fnqA:
7.85
6auvB-4fnqA:
7.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.49A 6auvA-4fnqA:
undetectable
6auvB-4fnqA:
undetectable		 6auvA-4fnqA:
7.85
6auvB-4fnqA:
7.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.49A 6auwA-4fnqA:
undetectable
6auwB-4fnqA:
undetectable		 6auwA-4fnqA:
7.85
6auwB-4fnqA:
7.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 6auxA-4fnqA:
undetectable
6auxB-4fnqA:
undetectable		 6auxA-4fnqA:
7.85
6auxB-4fnqA:
7.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.48A 6auyA-4fnqA:
undetectable
6auyB-4fnqA:
undetectable		 6auyA-4fnqA:
7.85
6auyB-4fnqA:
7.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.49A 6auzA-4fnqA:
undetectable
6auzB-4fnqA:
undetectable		 6auzA-4fnqA:
7.85
6auzB-4fnqA:
7.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.48A 6auzA-4fnqA:
undetectable
6auzB-4fnqA:
undetectable		 6auzA-4fnqA:
7.85
6auzB-4fnqA:
7.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 6av0A-4fnqA:
undetectable
6av0B-4fnqA:
undetectable		 6av0A-4fnqA:
7.85
6av0B-4fnqA:
7.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.47A 6av0A-4fnqA:
undetectable
6av0B-4fnqA:
undetectable		 6av0A-4fnqA:
7.85
6av0B-4fnqA:
7.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.46A 6av3A-4fnqA:
undetectable
6av3B-4fnqA:
undetectable		 6av3A-4fnqA:
7.85
6av3B-4fnqA:
7.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.49A 6av3A-4fnqA:
undetectable
6av3B-4fnqA:
undetectable		 6av3A-4fnqA:
7.85
6av3B-4fnqA:
7.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.49A 6av4A-4fnqA:
undetectable
6av4B-4fnqA:
undetectable		 6av4A-4fnqA:
7.85
6av4B-4fnqA:
7.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.47A 6av4A-4fnqA:
undetectable
6av4B-4fnqA:
undetectable		 6av4A-4fnqA:
7.85
6av4B-4fnqA:
7.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.49A 6av5A-4fnqA:
0.2
6av5B-4fnqA:
undetectable		 6av5A-4fnqA:
7.85
6av5B-4fnqA:
7.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_G_EY4G501_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ILE A 618
GLN A 621
VAL A 622
ILE A 360
 None
 0.66A 6cduF-4fnqA:
undetectable
6cduG-4fnqA:
undetectable		 6cduF-4fnqA:
18.90
6cduG-4fnqA:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 6cicA-4fnqA:
undetectable
6cicB-4fnqA:
undetectable		 6cicA-4fnqA:
7.85
6cicB-4fnqA:
7.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CIC_B_H4BB802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.48A 6cicA-4fnqA:
undetectable
6cicB-4fnqA:
undetectable		 6cicA-4fnqA:
7.85
6cicB-4fnqA:
7.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_A_H4BA802_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 ARG A 373
VAL A 412
TRP A 383
PHE A 370
 None
 1.48A 6cidA-4fnqA:
undetectable
6cidB-4fnqA:
undetectable		 6cidA-4fnqA:
7.85
6cidB-4fnqA:
7.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CID_B_H4BB803_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 7 TRP A 383
PHE A 370
ARG A 373
VAL A 412
 None
 1.47A 6cidA-4fnqA:
undetectable
6cidB-4fnqA:
undetectable		 6cidA-4fnqA:
7.85
6cidB-4fnqA:
7.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_A_GLYA715_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 GLY A 255
ASN A 256
SER A 225
ARG A 532
 None
 1.05A 6dwdA-4fnqA:
undetectable
6dwdC-4fnqA:
undetectable		 6dwdA-4fnqA:
21.83
6dwdC-4fnqA:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_A_BEZA502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 PHE A 343
VAL A 385
LEU A 410
LEU A 365
 None
 1.02A 6e43A-4fnqA:
undetectable		 6e43A-4fnqA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_B_BEZB502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 PHE A 343
VAL A 385
LEU A 410
LEU A 365
 None
 0.99A 6e43B-4fnqA:
undetectable		 6e43B-4fnqA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6E43_D_BEZD502_0
(INDOLEAMINE
2,3-DIOXYGENASE 1)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 PHE A 343
VAL A 385
LEU A 410
LEU A 365
 None
 0.97A 6e43D-4fnqA:
undetectable		 6e43D-4fnqA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		4 / 6 MET A 297
TRP A  36
LEU A  14
ALA A 152
 None
 1.08A 6fosB-4fnqA:
undetectable		 6fosB-4fnqA:
8.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
7DFR_A_FOLA161_1
(DIHYDROFOLATE
REDUCTASE)		 4fnq ALPHA-GALACTOSIDASE
AGAB
(Geobacillus
stearothermophil
us) 		3 / 3 ASP A 449
LEU A 432
ARG A 497
 None
 0.79A 7dfrA-4fnqA:
undetectable		 7dfrA-4fnqA:
11.33