SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fo7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4fo7 METHIONINE
AMINOPEPTIDASE
(Pseudomonas
aeruginosa) 		5 / 11 GLY A 106
HIS A 105
THR A 201
THR A 236
GLY A 171
 None
None
MN  A 301 ( 3.8A)
None
None
 1.00A 1c9sP-4fo7A:
undetectable
1c9sQ-4fo7A:
undetectable		 1c9sP-4fo7A:
15.30
1c9sQ-4fo7A:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4fo7 METHIONINE
AMINOPEPTIDASE
(Pseudomonas
aeruginosa) 		5 / 10 GLY A 171
GLY A 106
HIS A 105
THR A 201
THR A 236
 None
None
None
MN  A 301 ( 3.8A)
None
 1.01A 1gtfJ-4fo7A:
undetectable
1gtfK-4fo7A:
undetectable		 1gtfJ-4fo7A:
15.30
1gtfK-4fo7A:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4fo7 METHIONINE
AMINOPEPTIDASE
(Pseudomonas
aeruginosa) 		5 / 11 GLY A 106
HIS A 105
THR A 201
THR A 236
GLY A 171
 None
None
MN  A 301 ( 3.8A)
None
None
 0.99A 1gtfQ-4fo7A:
undetectable
1gtfR-4fo7A:
undetectable		 1gtfQ-4fo7A:
15.30
1gtfR-4fo7A:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4fo7 METHIONINE
AMINOPEPTIDASE
(Pseudomonas
aeruginosa) 		5 / 11 GLY A 106
HIS A 105
THR A 201
THR A 236
GLY A 171
 None
None
MN  A 301 ( 3.8A)
None
None
 0.97A 1gtfS-4fo7A:
undetectable
1gtfT-4fo7A:
undetectable		 1gtfS-4fo7A:
15.30
1gtfT-4fo7A:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4fo7 METHIONINE
AMINOPEPTIDASE
(Pseudomonas
aeruginosa) 		5 / 11 GLY A 106
HIS A 105
THR A 201
THR A 236
GLY A 171
 None
None
MN  A 301 ( 3.8A)
None
None
 0.98A 1gtnT-4fo7A:
undetectable
1gtnU-4fo7A:
undetectable		 1gtnT-4fo7A:
15.30
1gtnU-4fo7A:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4fo7 METHIONINE
AMINOPEPTIDASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 171
GLY A 106
HIS A 105
THR A 201
THR A 236
 None
None
None
MN  A 301 ( 3.8A)
None
 1.00A 1gtnL-4fo7A:
undetectable
1gtnV-4fo7A:
undetectable		 1gtnL-4fo7A:
15.30
1gtnV-4fo7A:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_E_TRPE81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fo7 METHIONINE
AMINOPEPTIDASE
(Pseudomonas
aeruginosa) 		5 / 10 GLY A 106
HIS A 105
THR A 201
THR A 236
GLY A 171
 None
None
MN  A 301 ( 3.8A)
None
None
 1.03A 1utdE-4fo7A:
undetectable
1utdF-4fo7A:
undetectable		 1utdE-4fo7A:
15.30
1utdF-4fo7A:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_H_TRPH81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fo7 METHIONINE
AMINOPEPTIDASE
(Pseudomonas
aeruginosa) 		5 / 10 GLY A 106
HIS A 105
THR A 201
THR A 236
GLY A 171
 None
None
MN  A 301 ( 3.8A)
None
None
 1.02A 1utdH-4fo7A:
undetectable
1utdI-4fo7A:
undetectable		 1utdH-4fo7A:
15.30
1utdI-4fo7A:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_L_TRPL81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fo7 METHIONINE
AMINOPEPTIDASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 106
HIS A 105
THR A 201
THR A 236
GLY A 171
 None
None
MN  A 301 ( 3.8A)
None
None
 0.96A 1utdL-4fo7A:
undetectable
1utdM-4fo7A:
undetectable		 1utdL-4fo7A:
15.30
1utdM-4fo7A:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_O_TRPO81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fo7 METHIONINE
AMINOPEPTIDASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 106
HIS A 105
THR A 201
THR A 236
GLY A 171
 None
None
MN  A 301 ( 3.8A)
None
None
 0.99A 1utdO-4fo7A:
undetectable
1utdP-4fo7A:
undetectable		 1utdO-4fo7A:
15.30
1utdP-4fo7A:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fo7 METHIONINE
AMINOPEPTIDASE
(Pseudomonas
aeruginosa) 		5 / 11 GLY A 106
HIS A 105
THR A 201
THR A 236
GLY A 171
 None
None
MN  A 301 ( 3.8A)
None
None
 0.99A 1utdS-4fo7A:
undetectable
1utdT-4fo7A:
undetectable		 1utdS-4fo7A:
15.30
1utdT-4fo7A:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_V_TRPV81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fo7 METHIONINE
AMINOPEPTIDASE
(Pseudomonas
aeruginosa) 		5 / 11 GLY A 171
GLY A 106
HIS A 105
THR A 201
THR A 236
 None
None
None
MN  A 301 ( 3.8A)
None
 0.97A 1utdL-4fo7A:
undetectable
1utdV-4fo7A:
undetectable		 1utdL-4fo7A:
15.30
1utdV-4fo7A:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_A_ADNA433_2
(ADENOSYLHOMOCYSTEINA
SE)		 4fo7 METHIONINE
AMINOPEPTIDASE
(Pseudomonas
aeruginosa) 		3 / 3 THR A  98
GLU A 203
HIS A  79
 None
MN  A 301 (-2.7A)
None
 0.68A 1xwfA-4fo7A:
undetectable		 1xwfA-4fo7A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_B_ADNB433_2
(ADENOSYLHOMOCYSTEINA
SE)		 4fo7 METHIONINE
AMINOPEPTIDASE
(Pseudomonas
aeruginosa) 		3 / 3 THR A  98
GLU A 203
HIS A  79
 None
MN  A 301 (-2.7A)
None
 0.67A 1xwfB-4fo7A:
undetectable		 1xwfB-4fo7A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_C_ADNC433_2
(ADENOSYLHOMOCYSTEINA
SE)		 4fo7 METHIONINE
AMINOPEPTIDASE
(Pseudomonas
aeruginosa) 		3 / 3 THR A  98
GLU A 203
HIS A  79
 None
MN  A 301 (-2.7A)
None
 0.70A 1xwfC-4fo7A:
undetectable		 1xwfC-4fo7A:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_D_ADND433_2
(ADENOSYLHOMOCYSTEINA
SE)		 4fo7 METHIONINE
AMINOPEPTIDASE
(Pseudomonas
aeruginosa) 		3 / 3 THR A  98
GLU A 203
HIS A  79
 None
MN  A 301 (-2.7A)
None
 0.65A 1xwfD-4fo7A:
undetectable		 1xwfD-4fo7A:
20.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YVM_A_TMGA501_1
(METHIONINE
AMINOPEPTIDASE)		 4fo7 METHIONINE
AMINOPEPTIDASE
(Pseudomonas
aeruginosa) 		5 / 7 TYR A  62
CYH A  70
HIS A  79
HIS A 177
TRP A 220
 None
 0.55A 1yvmA-4fo7A:
35.7		 1yvmA-4fo7A:
60.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BJF_A_DXCA330_0
(CHOLOYLGLYCINE
HYDROLASE)		 4fo7 METHIONINE
AMINOPEPTIDASE
(Pseudomonas
aeruginosa) 		5 / 12 PHE A 112
ASN A  83
ILE A  32
ILE A  28
THR A  38
 None
 1.30A 2bjfA-4fo7A:
undetectable		 2bjfA-4fo7A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_A_ACHA546_0
(ACETYLCHOLINESTERASE)		 4fo7 METHIONINE
AMINOPEPTIDASE
(Pseudomonas
aeruginosa) 		4 / 8 TYR A  62
GLU A 203
HIS A 170
GLY A 169
 None
MN  A 301 (-2.7A)
MN  A 301 (-3.5A)
None
 1.09A 2ha4A-4fo7A:
undetectable		 2ha4A-4fo7A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_B_ACHB603_0
(ACETYLCHOLINESTERASE)		 4fo7 METHIONINE
AMINOPEPTIDASE
(Pseudomonas
aeruginosa) 		4 / 7 TYR A  62
GLU A 203
HIS A 170
GLY A 169
 None
MN  A 301 (-2.7A)
MN  A 301 (-3.5A)
None
 1.03A 2ha4B-4fo7A:
undetectable		 2ha4B-4fo7A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_D_MTXD164_2
(DIHYDROFOLATE
REDUCTASE)		 4fo7 METHIONINE
AMINOPEPTIDASE
(Pseudomonas
aeruginosa) 		3 / 3 ARG A 250
ILE A  32
THR A 117
 None
 0.67A 3ia4D-4fo7A:
undetectable		 3ia4D-4fo7A:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_G_SAMG226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 4fo7 METHIONINE
AMINOPEPTIDASE
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 186
ALA A 188
GLY A 189
LEU A 145
ILE A 148
 None
 1.14A 3ku1G-4fo7A:
undetectable		 3ku1G-4fo7A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_A_FOLA301_1
(FOLATE RECEPTOR
ALPHA)		 4fo7 METHIONINE
AMINOPEPTIDASE
(Pseudomonas
aeruginosa) 		3 / 3 ASP A 107
TRP A 220
SER A 109
 MN  A 302 ( 2.7A)
None
None
 0.92A 4lrhA-4fo7A:
undetectable		 4lrhA-4fo7A:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DWK_C_ACTC207_0
(DIACYLGLYCEROL
KINASE)		 4fo7 METHIONINE
AMINOPEPTIDASE
(Pseudomonas
aeruginosa) 		4 / 5 GLU A  23
ALA A  22
GLU A  26
ASN A 251
 None
 1.44A 5dwkC-4fo7A:
undetectable		 5dwkC-4fo7A:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fo7 METHIONINE
AMINOPEPTIDASE
(Pseudomonas
aeruginosa) 		5 / 10 GLY A 171
GLY A 106
HIS A 105
THR A 201
THR A 236
 None
None
None
MN  A 301 ( 3.8A)
None
 1.02A 5eevA-4fo7A:
undetectable
5eevB-4fo7A:
undetectable		 5eevA-4fo7A:
15.30
5eevB-4fo7A:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fo7 METHIONINE
AMINOPEPTIDASE
(Pseudomonas
aeruginosa) 		5 / 10 GLY A 171
GLY A 106
HIS A 105
THR A 201
THR A 236
 None
None
None
MN  A 301 ( 3.8A)
None
 1.03A 5eewA-4fo7A:
undetectable
5eewB-4fo7A:
undetectable		 5eewA-4fo7A:
15.30
5eewB-4fo7A:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fo7 METHIONINE
AMINOPEPTIDASE
(Pseudomonas
aeruginosa) 		5 / 10 GLY A 171
GLY A 106
HIS A 105
THR A 201
THR A 236
 None
None
None
MN  A 301 ( 3.8A)
None
 1.02A 5eexA-4fo7A:
undetectable
5eexB-4fo7A:
undetectable		 5eexA-4fo7A:
15.30
5eexB-4fo7A:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fo7 METHIONINE
AMINOPEPTIDASE
(Pseudomonas
aeruginosa) 		5 / 10 GLY A 171
GLY A 106
HIS A 105
THR A 201
THR A 236
 None
None
None
MN  A 301 ( 3.8A)
None
 1.03A 5eeyA-4fo7A:
undetectable
5eeyB-4fo7A:
undetectable		 5eeyA-4fo7A:
15.30
5eeyB-4fo7A:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fo7 METHIONINE
AMINOPEPTIDASE
(Pseudomonas
aeruginosa) 		5 / 10 GLY A 171
GLY A 106
HIS A 105
THR A 201
THR A 236
 None
None
None
MN  A 301 ( 3.8A)
None
 1.03A 5eezA-4fo7A:
undetectable
5eezB-4fo7A:
undetectable		 5eezA-4fo7A:
15.30
5eezB-4fo7A:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fo7 METHIONINE
AMINOPEPTIDASE
(Pseudomonas
aeruginosa) 		5 / 10 GLY A 171
GLY A 106
HIS A 105
THR A 201
THR A 236
 None
None
None
MN  A 301 ( 3.8A)
None
 1.03A 5ef0A-4fo7A:
undetectable
5ef0B-4fo7A:
undetectable		 5ef0A-4fo7A:
15.30
5ef0B-4fo7A:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fo7 METHIONINE
AMINOPEPTIDASE
(Pseudomonas
aeruginosa) 		5 / 10 GLY A 171
GLY A 106
HIS A 105
THR A 201
THR A 236
 None
None
None
MN  A 301 ( 3.8A)
None
 1.03A 5ef1A-4fo7A:
undetectable
5ef1B-4fo7A:
undetectable		 5ef1A-4fo7A:
15.30
5ef1B-4fo7A:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fo7 METHIONINE
AMINOPEPTIDASE
(Pseudomonas
aeruginosa) 		5 / 10 GLY A 171
GLY A 106
HIS A 105
THR A 201
THR A 236
 None
None
None
MN  A 301 ( 3.8A)
None
 1.03A 5ef2A-4fo7A:
undetectable
5ef2B-4fo7A:
undetectable		 5ef2A-4fo7A:
15.30
5ef2B-4fo7A:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fo7 METHIONINE
AMINOPEPTIDASE
(Pseudomonas
aeruginosa) 		5 / 10 GLY A 171
GLY A 106
HIS A 105
THR A 201
THR A 236
 None
None
None
MN  A 301 ( 3.8A)
None
 1.03A 5ef3A-4fo7A:
undetectable
5ef3B-4fo7A:
undetectable		 5ef3A-4fo7A:
15.30
5ef3B-4fo7A:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NNW_D_GCSD302_1
(25 KDA PROTEIN
ELICITOR)		 4fo7 METHIONINE
AMINOPEPTIDASE
(Pseudomonas
aeruginosa) 		4 / 7 GLY A 169
HIS A 170
ASP A 107
HIS A  79
 None
MN  A 301 (-3.5A)
MN  A 302 ( 2.7A)
None
 0.70A 5nnwD-4fo7A:
undetectable		 5nnwD-4fo7A:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NO9_D_95ZD302_1
(25 KDA PROTEIN
ELICITOR)		 4fo7 METHIONINE
AMINOPEPTIDASE
(Pseudomonas
aeruginosa) 		4 / 7 GLY A 169
HIS A 170
ASP A 107
HIS A  79
 None
MN  A 301 (-3.5A)
MN  A 302 ( 2.7A)
None
 0.70A 5no9D-4fo7A:
undetectable		 5no9D-4fo7A:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_A_RFPA502_1
(RIFAMPIN
MONOOXYGENASE)		 4fo7 METHIONINE
AMINOPEPTIDASE
(Pseudomonas
aeruginosa) 		5 / 12 VAL A 163
LEU A 194
VAL A 139
THR A 201
GLY A 169
 None
None
None
MN  A 301 ( 3.8A)
None
 1.44A 6brdA-4fo7A:
undetectable		 6brdA-4fo7A:
16.61