SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4foz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1867_0
(FPRA)		 4foz PORIN D
(Pseudomonas
aeruginosa) 		4 / 4 ALA A 393
ARG A 337
GLN A 392
GLU A 373
 None
 1.48A 1lqtB-4fozA:
undetectable		 1lqtB-4fozA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_B_ACTB1873_0
(FPRA)		 4foz PORIN D
(Pseudomonas
aeruginosa) 		3 / 3 ASP A 351
ASP A 248
LYS A 357
 None
 1.09A 1lqtB-4fozA:
undetectable		 1lqtB-4fozA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1424_0
(FPRA)		 4foz PORIN D
(Pseudomonas
aeruginosa) 		4 / 4 ALA A 393
ARG A 337
GLN A 392
GLU A 373
 None
 1.48A 1lquB-4fozA:
undetectable		 1lquB-4fozA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_B_ACTB1430_0
(FPRA)		 4foz PORIN D
(Pseudomonas
aeruginosa) 		3 / 3 ASP A 351
ASP A 248
LYS A 357
 None
 1.09A 1lquB-4fozA:
undetectable		 1lquB-4fozA:
23.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_1
(DNA TOPOISOMERASE II)		 4foz PORIN D
(Pseudomonas
aeruginosa) 		4 / 7 HIS A 307
THR A 175
TYR A 176
TYR A 359
 None
 0.91A 1qzrA-4fozA:
undetectable		 1qzrA-4fozA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_2
(DNA TOPOISOMERASE II)		 4foz PORIN D
(Pseudomonas
aeruginosa) 		4 / 7 HIS A 307
THR A 175
TYR A 176
TYR A 359
 None
 0.88A 1qzrB-4fozA:
undetectable		 1qzrB-4fozA:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_A_ACHA546_0
(ACETYLCHOLINESTERASE)		 4foz PORIN D
(Pseudomonas
aeruginosa) 		4 / 8 TYR A 305
GLU A 313
TYR A 359
GLY A 310
 None
 0.99A 2ha4A-4fozA:
undetectable		 2ha4A-4fozA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HA4_B_ACHB603_0
(ACETYLCHOLINESTERASE)		 4foz PORIN D
(Pseudomonas
aeruginosa) 		4 / 7 TYR A 305
GLU A 313
TYR A 359
GLY A 310
 None
 1.00A 2ha4B-4fozA:
undetectable		 2ha4B-4fozA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PIW_A_T3A933_1
(ANDROGEN RECEPTOR)		 4foz PORIN D
(Pseudomonas
aeruginosa) 		5 / 10 ASN A 301
GLU A 369
ASN A 371
GLU A 373
ARG A 389
 None
 1.44A 2piwA-4fozA:
undetectable		 2piwA-4fozA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNC_A_CLUA808_1
(COPPER AMINE
OXIDASE, LIVER
ISOZYME)		 4foz PORIN D
(Pseudomonas
aeruginosa) 		4 / 7 ALA A 264
TYR A 327
TYR A 320
HIS A 265
 None
 1.27A 2pncA-4fozA:
undetectable		 2pncA-4fozA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MB5_A_SAMA301_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 4foz PORIN D
(Pseudomonas
aeruginosa) 		4 / 4 GLY A 149
GLU A 148
ASP A 195
ASP A 151
 None
 1.41A 3mb5A-4fozA:
undetectable		 3mb5A-4fozA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRI_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 4foz PORIN D
(Pseudomonas
aeruginosa) 		4 / 5 LEU A  47
GLY A  45
THR A  43
ILE A 412
 None
 0.88A 3wriA-4fozA:
undetectable		 3wriA-4fozA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRI_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 4foz PORIN D
(Pseudomonas
aeruginosa) 		4 / 5 LEU A  47
GLY A  45
THR A  43
ILE A 412
 None
 0.88A 3wriB-4fozA:
undetectable		 3wriB-4fozA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_C_ACTC1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 4foz PORIN D
(Pseudomonas
aeruginosa) 		3 / 3 TYR A 236
THR A 238
THR A 253
 None
 0.34A 5aoxB-4fozA:
undetectable		 5aoxB-4fozA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_F_ACTF1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 4foz PORIN D
(Pseudomonas
aeruginosa) 		3 / 3 TYR A 236
THR A 238
THR A 253
 None
 0.28A 5aoxE-4fozA:
0.5		 5aoxE-4fozA:
13.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TJZ_A_BEZA302_0
(4-HYDROXY-TETRAHYDRO
DIPICOLINATE
REDUCTASE)		 4foz PORIN D
(Pseudomonas
aeruginosa) 		3 / 3 MET A 335
GLU A 369
ARG A 337
 None
 0.92A 5tjzA-4fozA:
undetectable		 5tjzA-4fozA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BKL_G_EU7G101_0
(MATRIX PROTEIN 2)		 4foz PORIN D
(Pseudomonas
aeruginosa) 		5 / 9 ALA A 199
SER A 200
ALA A 192
SER A 198
GLY A 149
 None
 1.15A 6bklE-4fozA:
undetectable
6bklF-4fozA:
undetectable
6bklG-4fozA:
undetectable
6bklH-4fozA:
undetectable		 6bklE-4fozA:
3.99
6bklF-4fozA:
3.99
6bklG-4fozA:
3.99
6bklH-4fozA:
3.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BOC_A_EU7A102_0
(MATRIX PROTEIN 2)		 4foz PORIN D
(Pseudomonas
aeruginosa) 		4 / 6 ALA A 199
SER A 200
ALA A 192
SER A 198
 None
 0.96A 6bocA-4fozA:
undetectable
6bocB-4fozA:
undetectable
6bocC-4fozA:
undetectable
6bocD-4fozA:
undetectable		 6bocA-4fozA:
3.99
6bocB-4fozA:
3.99
6bocC-4fozA:
3.99
6bocD-4fozA:
3.99