SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fp8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NED_A_PFNA709_1 (LACTOTRANSFERRIN)	4fp8	ANTIBODY C05, HEAVY CHAIN (Homo sapiens)	4 / 6	ASP H 100 ASP H 101 SER H 27 ALA H 33	None	1.17A	4nedA-4fp8H: undetectable	4nedA-4fp8H: 21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4X1K_D_LOCD502_1 (TUBULIN ALPHA CHAIN TUBULIN BETA CHAIN)	4fp8	ANTIBODY C05, HEAVY CHAIN (Homo sapiens)	4 / 4	ASN H 52 SER H 97 ALA H 33 VAL H 34	None	1.04A	4x1kC-4fp8H: undetectable	4x1kC-4fp8H: 19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NM5_B_LOCB502_1 (TUBULIN ALPHA-1B CHAIN TUBULIN BETA-2B CHAIN)	4fp8	ANTIBODY C05, HEAVY CHAIN (Homo sapiens)	4 / 4	ASN H 52 SER H 97 ALA H 33 VAL H 34	None	0.84A	5nm5A-4fp8H: undetectable	5nm5A-4fp8H: 19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XOO_A_ADNA506_1 (GLYCOSAMINOGLYCAN XYLOSYLKINASE)	4fp8	ANTIBODY C05, HEAVY CHAIN (Homo sapiens)	4 / 6	TYR H 79 LEU H 4 GLU H 76 LEU H 29	None	1.32A	5xooA-4fp8H: undetectable	5xooA-4fp8H: 15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BPY_A_ACTA408_0 (THIOREDOXIN REDUCTASE)	4fp8	ANTIBODY C05, HEAVY CHAIN (Homo sapiens)	3 / 3	PRO H 185 SER H 187 SER H 188	None	0.55A	6bpyA-4fp8H: undetectable	6bpyA-4fp8H: 21.28

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4NED_A_PFNA709_1","LACTOTRANSFERRIN","4fp8","ANTIBODY C05, HEAVY CHAIN","Homo sapiens",4,"ASP H 100;ASP H 101;SER H  27;ALA H  33","None","1.17A","4nedA-4fp8H:undetectable","4nedA-4fp8H:21.70"],["4X1K_D_LOCD502_1","TUBULIN ALPHA CHAIN;TUBULIN BETA CHAIN","4fp8","ANTIBODY C05, HEAVY CHAIN","Homo sapiens",4,"ASN H  52;SER H  97;ALA H  33;VAL H  34","None","1.04A","4x1kC-4fp8H:undetectable","4x1kC-4fp8H:19.21"],["5NM5_B_LOCB502_1","TUBULIN ALPHA-1B CHAIN;TUBULIN BETA-2B CHAIN","4fp8","ANTIBODY C05, HEAVY CHAIN","Homo sapiens",4,"ASN H  52;SER H  97;ALA H  33;VAL H  34","None","0.84A","5nm5A-4fp8H:undetectable","5nm5A-4fp8H:19.38"],["5XOO_A_ADNA506_1","GLYCOSAMINOGLYCAN XYLOSYLKINASE","4fp8","ANTIBODY C05, HEAVY CHAIN","Homo sapiens",4,"TYR H  79;LEU H   4;GLU H  76;LEU H  29","None","1.32A","5xooA-4fp8H:undetectable","5xooA-4fp8H:15.81"],["6BPY_A_ACTA408_0","THIOREDOXIN REDUCTASE","4fp8","ANTIBODY C05, HEAVY CHAIN","Homo sapiens",3,"PRO H 185;SER H 187;SER H 188","None","0.55A","6bpyA-4fp8H:undetectable","6bpyA-4fp8H:21.28"]]