SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fpw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMM_A_SAMA301_0
(UPF0217 PROTEIN
AF_1056)		 4fpw CALU16
(Micromonospora
echinospora) 		5 / 9 LEU A 122
ILE A  24
GLY A 126
GLY A 128
SER A 118
 None
 1.04A 2qmmA-4fpwA:
undetectable		 2qmmA-4fpwA:
24.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L78_A_ACTA1327_0
(PHOSPHORIBOSYLFORMYL
GLYCINAMIDINE
SYNTHASE)		 4fpw CALU16
(Micromonospora
echinospora) 		4 / 4 VAL A  34
THR A 108
GLU A 103
GLU A 104
 None
 1.44A 4l78A-4fpwA:
undetectable		 4l78A-4fpwA:
9.84