SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fq7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3004_1
(SERUM ALBUMIN)		 4fq7 MALEATE CIS-TRANS
ISOMERASE
(Pseudomonas
putida) 		4 / 6 PHE A  39
GLU A  37
LEU A 235
VAL A  77
 None
 1.08A 1hk1A-4fq7A:
undetectable		 1hk1A-4fq7A:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A35_A_RBFA191_1
(LUMAZINE PROTEIN)		 4fq7 MALEATE CIS-TRANS
ISOMERASE
(Pseudomonas
putida) 		5 / 12 LEU A 206
ALA A 224
THR A 227
THR A 228
ILE A  24
 None
 1.15A 3a35A-4fq7A:
undetectable		 3a35A-4fq7A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A3B_A_RBFA191_1
(LUMAZINE PROTEIN)		 4fq7 MALEATE CIS-TRANS
ISOMERASE
(Pseudomonas
putida) 		5 / 12 LEU A 206
ALA A 224
THR A 227
THR A 228
ILE A  24
 None
 1.16A 3a3bA-4fq7A:
undetectable		 3a3bA-4fq7A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		 4fq7 MALEATE CIS-TRANS
ISOMERASE
(Pseudomonas
putida) 		4 / 6 ALA A 118
LEU A 121
ALA A 199
THR A 137
 None
 0.82A 3b6hA-4fq7A:
undetectable		 3b6hA-4fq7A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_B_MXDB551_1
(PROSTACYCLIN
SYNTHASE)		 4fq7 MALEATE CIS-TRANS
ISOMERASE
(Pseudomonas
putida) 		4 / 6 ALA A 118
LEU A 121
ALA A 199
THR A 137
 None
 0.85A 3b6hB-4fq7A:
undetectable		 3b6hB-4fq7A:
18.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BA0_A_HAEA477_1
(MACROPHAGE
METALLOELASTASE)		 4fq7 MALEATE CIS-TRANS
ISOMERASE
(Pseudomonas
putida) 		3 / 3 HIS A  91
GLU A 154
HIS A  94
 None
 0.79A 3ba0A-4fq7A:
3.3		 3ba0A-4fq7A:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_B_V2HB602_0
(CYTOCHROME P450 2R1)		 4fq7 MALEATE CIS-TRANS
ISOMERASE
(Pseudomonas
putida) 		5 / 12 MET A  20
THR A  19
ALA A 226
ALA A  81
ILE A 197
 None
 0.89A 3dl9B-4fq7A:
undetectable		 3dl9B-4fq7A:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_D_MTXD164_2
(DIHYDROFOLATE
REDUCTASE)		 4fq7 MALEATE CIS-TRANS
ISOMERASE
(Pseudomonas
putida) 		3 / 3 ARG A 126
ILE A 221
THR A 137
 None
 0.65A 3ia4D-4fq7A:
undetectable		 3ia4D-4fq7A:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LS4_H_TCIH220_1
(HEAVY CHAIN OF
ANTIBODY FAB
FRAGMENT)		 4fq7 MALEATE CIS-TRANS
ISOMERASE
(Pseudomonas
putida) 		5 / 10 VAL A 225
LEU A  27
SER A 222
GLY A 245
GLY A 243
 None
 1.19A 3ls4H-4fq7A:
undetectable		 3ls4H-4fq7A:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RET_A_SALA201_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 4fq7 MALEATE CIS-TRANS
ISOMERASE
(Pseudomonas
putida) 		5 / 10 VAL A 133
ALA A 127
ARG A 126
ILE A 221
ILE A 156
 None
 1.31A 3retA-4fq7A:
undetectable
3retB-4fq7A:
undetectable		 3retA-4fq7A:
15.38
3retB-4fq7A:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TTP_A_017A201_1
(HIV-1 PROTEASE)		 4fq7 MALEATE CIS-TRANS
ISOMERASE
(Pseudomonas
putida) 		5 / 10 GLY A 119
ALA A 118
GLY A  79
ILE A 114
ILE A  86
 None
 0.98A 3ttpA-4fq7A:
undetectable		 3ttpA-4fq7A:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 4fq7 MALEATE CIS-TRANS
ISOMERASE
(Pseudomonas
putida) 		5 / 12 ALA A 223
SER A 222
VAL A 196
ILE A 125
HIS A  94
 None
 1.06A 4c49A-4fq7A:
undetectable		 4c49A-4fq7A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYC_A_1YNA502_1
(PROTEIN CYP51)		 4fq7 MALEATE CIS-TRANS
ISOMERASE
(Pseudomonas
putida) 		5 / 12 ALA A 194
TYR A 139
ALA A 171
ALA A 173
THR A  19
 None
 1.29A 6aycA-4fq7A:
undetectable		 6aycA-4fq7A:
13.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_C_RFPC502_1
(RIFAMPIN
MONOOXYGENASE)		 4fq7 MALEATE CIS-TRANS
ISOMERASE
(Pseudomonas
putida) 		5 / 12 VAL A 135
VAL A 158
GLY A  92
MET A  87
GLY A 124
 None
 1.12A 6brdC-4fq7A:
undetectable		 6brdC-4fq7A:
15.58