SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fqd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 9 SER A 252
GLY A 203
ALA A 233
HIS A 207
ILE A 245
 None
 1.16A 1c9sA-4fqdA:
undetectable
1c9sB-4fqdA:
undetectable		 1c9sA-4fqdA:
9.50
1c9sB-4fqdA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 9 GLY A 203
ALA A 233
HIS A 207
ILE A 245
SER A 252
 None
 1.15A 1c9sL-4fqdA:
undetectable
1c9sM-4fqdA:
undetectable		 1c9sL-4fqdA:
9.50
1c9sM-4fqdA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 10 GLY A 203
ALA A 233
HIS A 207
ILE A 245
SER A 252
 None
 1.16A 1c9sN-4fqdA:
undetectable
1c9sO-4fqdA:
undetectable		 1c9sN-4fqdA:
9.50
1c9sO-4fqdA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 9 GLY A 203
ALA A 233
HIS A 207
ILE A 245
SER A 252
 None
 1.16A 1c9sO-4fqdA:
undetectable
1c9sP-4fqdA:
undetectable		 1c9sO-4fqdA:
9.50
1c9sP-4fqdA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 9 GLY A 203
ALA A 233
HIS A 207
ILE A 245
SER A 252
 None
 1.14A 1c9sQ-4fqdA:
undetectable
1c9sR-4fqdA:
undetectable		 1c9sQ-4fqdA:
9.50
1c9sR-4fqdA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 9 GLY A 203
ALA A 233
HIS A 207
ILE A 245
SER A 252
 None
 1.17A 1c9sS-4fqdA:
undetectable
1c9sT-4fqdA:
undetectable		 1c9sS-4fqdA:
9.50
1c9sT-4fqdA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 10 SER A 252
GLY A 203
ALA A 233
HIS A 207
ILE A 245
 None
 1.13A 1c9sL-4fqdA:
undetectable
1c9sV-4fqdA:
undetectable		 1c9sL-4fqdA:
9.50
1c9sV-4fqdA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 9 GLY A 203
ALA A 233
HIS A 207
ILE A 245
SER A 252
 None
 1.15A 1gtfO-4fqdA:
undetectable
1gtfP-4fqdA:
undetectable		 1gtfO-4fqdA:
9.50
1gtfP-4fqdA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 10 GLY A 203
ALA A 233
HIS A 207
ILE A 245
SER A 252
 None
 1.16A 1gtfP-4fqdA:
undetectable
1gtfQ-4fqdA:
undetectable		 1gtfP-4fqdA:
9.50
1gtfQ-4fqdA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 11 GLY A 203
ALA A 233
HIS A 207
ILE A 245
SER A 252
 None
 1.15A 1gtfQ-4fqdA:
undetectable
1gtfR-4fqdA:
undetectable		 1gtfQ-4fqdA:
9.50
1gtfR-4fqdA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 9 GLY A 203
ALA A 233
HIS A 207
ILE A 245
SER A 252
 None
 1.15A 1gtfR-4fqdA:
undetectable
1gtfS-4fqdA:
undetectable		 1gtfR-4fqdA:
9.50
1gtfS-4fqdA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 10 SER A 252
GLY A 203
ALA A 233
HIS A 207
ILE A 245
 None
 1.16A 1gtfL-4fqdA:
undetectable
1gtfV-4fqdA:
undetectable		 1gtfL-4fqdA:
9.50
1gtfV-4fqdA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 11 GLY A 203
ALA A 233
HIS A 207
ILE A 245
SER A 252
 None
 1.15A 1gtnM-4fqdA:
undetectable
1gtnN-4fqdA:
undetectable		 1gtnM-4fqdA:
9.50
1gtnN-4fqdA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 10 GLY A 203
ALA A 233
HIS A 207
ILE A 245
SER A 252
 None
 1.12A 1gtnN-4fqdA:
undetectable
1gtnO-4fqdA:
undetectable		 1gtnN-4fqdA:
9.50
1gtnO-4fqdA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 9 GLY A 203
ALA A 233
HIS A 207
ILE A 245
SER A 252
 None
 1.07A 1gtnR-4fqdA:
undetectable
1gtnS-4fqdA:
undetectable		 1gtnR-4fqdA:
9.50
1gtnS-4fqdA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 11 GLY A 203
ALA A 233
HIS A 207
ILE A 245
SER A 252
 None
 1.09A 1gtnT-4fqdA:
undetectable
1gtnU-4fqdA:
undetectable		 1gtnT-4fqdA:
9.50
1gtnU-4fqdA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 10 GLY A 203
ALA A 233
HIS A 207
ILE A 245
SER A 252
 None
 1.15A 1gtnU-4fqdA:
undetectable
1gtnV-4fqdA:
undetectable		 1gtnU-4fqdA:
9.50
1gtnV-4fqdA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIN_A_KTNA801_1
(CYTOCHROME P450
107A1)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 11 TYR A 438
VAL A 414
ALA A 418
ALA A 421
LEU A 445
 None
 1.06A 1jinA-4fqdA:
undetectable		 1jinA-4fqdA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K5Q_B_PACB559_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		4 / 7 SER A 252
PRO A 250
ALA A  47
ALA A 233
 None
 1.02A 1k5qA-4fqdA:
undetectable
1k5qB-4fqdA:
undetectable		 1k5qA-4fqdA:
16.11
1k5qB-4fqdA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1869_0
(FPRA)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		4 / 4 ASP A 451
HIS A  19
ARG A 453
GLU A  17
 None
 1.07A 1lqtA-4fqdA:
undetectable		 1lqtA-4fqdA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1426_0
(FPRA)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		4 / 4 ASP A 451
HIS A  19
ARG A 453
GLU A  17
 None
 1.00A 1lquA-4fqdA:
0.0		 1lquA-4fqdA:
22.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_D_SAMD200_0
(METHIONINE REPRESSOR)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 12 GLY A 401
GLU A 374
LEU A 415
ALA A 419
LEU A 378
 None
 1.03A 1mjqC-4fqdA:
undetectable
1mjqD-4fqdA:
undetectable		 1mjqC-4fqdA:
12.07
1mjqD-4fqdA:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_J_SAMJ200_0
(METHIONINE REPRESSOR)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 12 GLY A 401
GLU A 374
LEU A 415
ALA A 419
LEU A 378
 None
 1.04A 1mjqI-4fqdA:
undetectable
1mjqJ-4fqdA:
undetectable		 1mjqI-4fqdA:
12.07
1mjqJ-4fqdA:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N13_B_AG2B7011_1
(PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE ALPHA
CHAIN
PYRUVOYL-DEPENDENT
ARGININE
DECARBOXYLASE BETA
CHAIN)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		4 / 5 ARG A 439
LEU A 448
ASP A 444
LEU A 441
 None
 1.21A 1n13B-4fqdA:
undetectable
1n13C-4fqdA:
undetectable		 1n13B-4fqdA:
13.84
1n13C-4fqdA:
8.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN0_B_T44B602_1
(TRANSTHYRETIN)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		4 / 7 LEU A 277
ALA A 418
LEU A 375
ALA A 352
 None
 1.03A 1sn0B-4fqdA:
undetectable
1sn0D-4fqdA:
undetectable		 1sn0B-4fqdA:
15.93
1sn0D-4fqdA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN0_B_T44B602_1
(TRANSTHYRETIN)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		4 / 7 LEU A 375
ALA A 352
LEU A 277
ALA A 418
 None
 1.04A 1sn0B-4fqdA:
undetectable
1sn0D-4fqdA:
undetectable		 1sn0B-4fqdA:
15.93
1sn0D-4fqdA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_Q_TRPQ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 10 GLY A 203
ALA A 233
HIS A 207
ILE A 245
SER A 252
 None
 1.13A 1utdQ-4fqdA:
undetectable
1utdR-4fqdA:
undetectable		 1utdQ-4fqdA:
9.50
1utdR-4fqdA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 10 GLY A 203
ALA A 233
HIS A 207
ILE A 245
SER A 252
 None
 1.14A 1utdR-4fqdA:
undetectable
1utdS-4fqdA:
undetectable		 1utdR-4fqdA:
9.50
1utdS-4fqdA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_S_TRPS81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 11 GLY A 203
ALA A 233
HIS A 207
ILE A 245
SER A 252
 None
 1.12A 1utdS-4fqdA:
undetectable
1utdT-4fqdA:
undetectable		 1utdS-4fqdA:
9.50
1utdT-4fqdA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_A_ACTA294_0
(GLYCINE
N-METHYLTRANSFERASE)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		4 / 5 ILE A 380
LEU A 389
ALA A 372
GLU A 376
 None
 0.95A 1xvaA-4fqdA:
undetectable
1xvaB-4fqdA:
undetectable		 1xvaA-4fqdA:
23.64
1xvaB-4fqdA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2002_1
(SERUM ALBUMIN)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 10 ALA A  45
ALA A  43
LEU A 228
LEU A 201
ALA A 204
 None
 0.92A 2bxeA-4fqdA:
undetectable		 2bxeA-4fqdA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2002_1
(SERUM ALBUMIN)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 10 ALA A  45
LEU A 228
LEU A 201
ALA A 204
LEU A 111
 None
 1.04A 2bxeA-4fqdA:
undetectable		 2bxeA-4fqdA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXG_B_IBPB2002_1
(SERUM ALBUMIN)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		6 / 10 ALA A  45
ALA A  43
LEU A 228
LEU A 201
ALA A 204
LEU A 111
 None
 1.35A 2bxgB-4fqdA:
undetectable		 2bxgB-4fqdA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9W_A_PAUA6002_0
(PANTOTHENATE KINASE)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		4 / 8 THR A 260
GLY A 289
ASP A 291
ARG A 292
 None
 0.86A 2f9wA-4fqdA:
undetectable
2f9wB-4fqdA:
undetectable		 2f9wA-4fqdA:
22.59
2f9wB-4fqdA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_A_RALA600_1
(ESTROGEN RECEPTOR)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 12 ALA A 406
GLU A 374
LEU A 415
ILE A 452
LEU A 434
 None
 1.07A 2jfaA-4fqdA:
undetectable		 2jfaA-4fqdA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WQ5_A_MIYA1120_1
(PHOSPHOLIPASE A2,
ACIDIC)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		4 / 7 LEU A  37
ALA A  63
GLY A  66
ARG A  70
 None
 0.94A 2wq5A-4fqdA:
undetectable		 2wq5A-4fqdA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHN_A_ACTA108_0
(PROTEIN P-30)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		3 / 3 THR A 158
SER A 162
ARG A 123
 None
 0.69A 3phnA-4fqdA:
undetectable		 3phnA-4fqdA:
10.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9C_A_ECLA452_1
(CYTOCHROME P450
164A2)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 12 PRO A 397
LEU A 378
LEU A 404
ALA A 418
LEU A 420
 None
 1.15A 3r9cA-4fqdA:
undetectable		 3r9cA-4fqdA:
24.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 9 ASP A 291
ILE A 290
GLY A 289
GLY A  32
ARG A 410
 None
 1.22A 4acaB-4fqdA:
undetectable
4acaC-4fqdA:
undetectable		 4acaB-4fqdA:
21.01
4acaC-4fqdA:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_0
(METHYLTRANSFERASE
WBDD)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 12 GLY A 275
ALA A 279
ILE A 272
LEU A 323
HIS A 321
 None
 1.30A 4azsA-4fqdA:
undetectable		 4azsA-4fqdA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_A_IPHA101_0
(INSULIN)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 10 CYH A 273
LEU A 417
ALA A 418
LEU A 350
LEU A 375
 None
 1.26A 4p65A-4fqdA:
undetectable
4p65B-4fqdA:
undetectable
4p65F-4fqdA:
undetectable
4p65H-4fqdA:
undetectable		 4p65A-4fqdA:
3.82
4p65B-4fqdA:
4.30
4p65F-4fqdA:
4.30
4p65H-4fqdA:
4.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QN9_B_DXCB610_0
(N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		3 / 3 GLY A 249
PRO A 250
ALA A  47
 None
 0.53A 4qn9B-4fqdA:
undetectable		 4qn9B-4fqdA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1F_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 12 ASP A 164
LEU A 165
LEU A 145
ARG A 156
LEU A 157
 None
 0.88A 4x1fA-4fqdA:
undetectable		 4x1fA-4fqdA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1G_A_3WFA501_1
(NUCLEAR RECEPTOR
SUBFAMILY 1 GROUP I
MEMBER 2)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 12 ASP A 164
LEU A 165
LEU A 145
ARG A 156
LEU A 157
 None
 0.89A 4x1gA-4fqdA:
undetectable		 4x1gA-4fqdA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XT7_A_TOPA302_1
(RV2671)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 11 THR A  30
SER A  31
GLY A  32
GLU A 267
THR A  62
 None
 1.33A 4xt7A-4fqdA:
undetectable		 4xt7A-4fqdA:
23.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 10 GLY A 203
ALA A 233
HIS A 207
ILE A 245
SER A 252
 None
 1.15A 5eeuR-4fqdA:
undetectable
5eeuS-4fqdA:
undetectable		 5eeuR-4fqdA:
9.50
5eeuS-4fqdA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 10 GLY A 203
ALA A 233
HIS A 207
ILE A 245
SER A 252
 None
 1.13A 5eeuS-4fqdA:
undetectable
5eeuT-4fqdA:
undetectable		 5eeuS-4fqdA:
9.50
5eeuT-4fqdA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 10 GLY A 203
ALA A 233
HIS A 207
ILE A 245
SER A 252
 None
 1.15A 5eevR-4fqdA:
undetectable
5eevS-4fqdA:
undetectable		 5eevR-4fqdA:
9.50
5eevS-4fqdA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 10 GLY A 203
ALA A 233
HIS A 207
ILE A 245
SER A 252
 None
 1.13A 5eevS-4fqdA:
undetectable
5eevT-4fqdA:
undetectable		 5eevS-4fqdA:
9.50
5eevT-4fqdA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 10 GLY A 203
ALA A 233
HIS A 207
ILE A 245
SER A 252
 None
 1.15A 5eewR-4fqdA:
undetectable
5eewS-4fqdA:
undetectable		 5eewR-4fqdA:
9.50
5eewS-4fqdA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 10 GLY A 203
ALA A 233
HIS A 207
ILE A 245
SER A 252
 None
 1.13A 5eewS-4fqdA:
undetectable
5eewT-4fqdA:
undetectable		 5eewS-4fqdA:
9.50
5eewT-4fqdA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 10 GLY A 203
ALA A 233
HIS A 207
ILE A 245
SER A 252
 None
 1.15A 5eexR-4fqdA:
undetectable
5eexS-4fqdA:
undetectable		 5eexR-4fqdA:
9.50
5eexS-4fqdA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 10 GLY A 203
ALA A 233
HIS A 207
ILE A 245
SER A 252
 None
 1.13A 5eexS-4fqdA:
undetectable
5eexT-4fqdA:
undetectable		 5eexS-4fqdA:
9.50
5eexT-4fqdA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 10 GLY A 203
ALA A 233
HIS A 207
ILE A 245
SER A 252
 None
 1.16A 5eeyR-4fqdA:
undetectable
5eeyS-4fqdA:
undetectable		 5eeyR-4fqdA:
9.50
5eeyS-4fqdA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 10 GLY A 203
ALA A 233
HIS A 207
ILE A 245
SER A 252
 None
 1.13A 5eeyS-4fqdA:
undetectable
5eeyT-4fqdA:
undetectable		 5eeyS-4fqdA:
9.50
5eeyT-4fqdA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 10 GLY A 203
ALA A 233
HIS A 207
ILE A 245
SER A 252
 None
 1.15A 5eezR-4fqdA:
undetectable
5eezS-4fqdA:
undetectable		 5eezR-4fqdA:
9.50
5eezS-4fqdA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 10 GLY A 203
ALA A 233
HIS A 207
ILE A 245
SER A 252
 None
 1.13A 5eezS-4fqdA:
undetectable
5eezT-4fqdA:
undetectable		 5eezS-4fqdA:
9.50
5eezT-4fqdA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 10 GLY A 203
ALA A 233
HIS A 207
ILE A 245
SER A 252
 None
 1.16A 5ef0R-4fqdA:
undetectable
5ef0S-4fqdA:
undetectable		 5ef0R-4fqdA:
9.50
5ef0S-4fqdA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 10 GLY A 203
ALA A 233
HIS A 207
ILE A 245
SER A 252
 None
 1.13A 5ef0S-4fqdA:
undetectable
5ef0T-4fqdA:
undetectable		 5ef0S-4fqdA:
9.50
5ef0T-4fqdA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 10 GLY A 203
ALA A 233
HIS A 207
ILE A 245
SER A 252
 None
 1.16A 5ef1R-4fqdA:
undetectable
5ef1S-4fqdA:
undetectable		 5ef1R-4fqdA:
9.50
5ef1S-4fqdA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 10 GLY A 203
ALA A 233
HIS A 207
ILE A 245
SER A 252
 None
 1.13A 5ef1S-4fqdA:
undetectable
5ef1T-4fqdA:
undetectable		 5ef1S-4fqdA:
9.50
5ef1T-4fqdA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 10 GLY A 203
ALA A 233
HIS A 207
ILE A 245
SER A 252
 None
 1.16A 5ef2R-4fqdA:
undetectable
5ef2S-4fqdA:
undetectable		 5ef2R-4fqdA:
9.50
5ef2S-4fqdA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 10 GLY A 203
ALA A 233
HIS A 207
ILE A 245
SER A 252
 None
 1.14A 5ef2S-4fqdA:
undetectable
5ef2T-4fqdA:
undetectable		 5ef2S-4fqdA:
9.50
5ef2T-4fqdA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 10 GLY A 203
ALA A 233
HIS A 207
ILE A 245
SER A 252
 None
 1.16A 5ef3R-4fqdA:
undetectable
5ef3S-4fqdA:
undetectable		 5ef3R-4fqdA:
9.50
5ef3S-4fqdA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 10 GLY A 203
ALA A 233
HIS A 207
ILE A 245
SER A 252
 None
 1.14A 5ef3S-4fqdA:
undetectable
5ef3T-4fqdA:
undetectable		 5ef3S-4fqdA:
9.50
5ef3T-4fqdA:
9.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPU_A_IPHA101_0
(INSULIN, CHAIN A
INSULIN, CHAIN B)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		4 / 4 CYH A 273
LEU A 349
LEU A 417
ALA A 418
 None
 1.07A 5hpuA-4fqdA:
undetectable
5hpuB-4fqdA:
undetectable		 5hpuA-4fqdA:
3.82
5hpuB-4fqdA:
13.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HV1_A_RFPA902_1
(PHOSPHOENOLPYRUVATE
SYNTHASE)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 12 VAL A  41
ALA A  89
LEU A 228
LEU A  97
MET A 148
 None
 1.21A 5hv1A-4fqdA:
undetectable		 5hv1A-4fqdA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND3_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 12 VAL A 147
ASP A 146
LEU A 200
ALA A 199
THR A 242
 None
 1.24A 5nd3B-4fqdA:
undetectable		 5nd3B-4fqdA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_B_ACTB405_0
(THIOREDOXIN
REDUCTASE)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		3 / 3 GLY A 107
LEU A 109
HIS A 106
 None
None
SO4  A 501 (-4.1A)
 0.68A 5u63B-4fqdA:
undetectable		 5u63B-4fqdA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_2
(CYTOCHROME P450 3A4)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		3 / 3 ARG A 361
ARG A 182
ARG A 368
 None
None
SO4  A 502 ( 4.5A)
 0.95A 5vcgA-4fqdA:
undetectable		 5vcgA-4fqdA:
24.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOP_A_C2FA3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 12 GLY A  66
VAL A 227
LEU A 231
VAL A 259
ILE A  53
 None
 0.91A 5vopA-4fqdA:
undetectable		 5vopA-4fqdA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_B_CHDB401_0
(BILE SALT HYDROLASE)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 10 LEU A 350
ILE A 380
LEU A 378
LEU A 416
LEU A 278
 None
 1.24A 5y7pB-4fqdA:
undetectable		 5y7pB-4fqdA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_D_CHDD401_0
(BILE SALT HYDROLASE)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 10 LEU A 350
ILE A 380
LEU A 378
LEU A 416
LEU A 278
 None
 1.19A 5y7pD-4fqdA:
undetectable		 5y7pD-4fqdA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_H_CHDH401_0
(BILE SALT HYDROLASE)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 10 LEU A 350
ILE A 380
LEU A 378
LEU A 416
LEU A 278
 None
 1.25A 5y7pH-4fqdA:
undetectable		 5y7pH-4fqdA:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_A_SAMA901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 12 PHE A 340
HIS A 106
VAL A 269
ILE A 266
ASP A 264
 None
SO4  A 501 (-4.1A)
None
None
None
 1.49A 6bxnA-4fqdA:
undetectable		 6bxnA-4fqdA:
20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_0
(STIE PROTEIN)		 4fqd NIKO PROTEIN
(Streptomyces
tendae) 		5 / 12 LEU A 265
ASP A 316
ILE A 272
VAL A 294
LEU A 297
 None
 0.93A 6ecxA-4fqdA:
undetectable		 6ecxA-4fqdA:
21.46