SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fqj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
11GS_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE)		 4fqj HEMAGGLUTININ
(Influenza
B
virus) 		4 / 7 TYR A 202
VAL A 160
ILE A 243
GLY A 138
 None
 0.93A 11gsA-4fqjA:
undetectable		 11gsA-4fqjA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_A_CCSA47_0
(GLUTATHIONE
S-TRANSFERASE)		 4fqj HEMAGGLUTININ
(Influenza
B
virus) 		4 / 7 LEU A 286
LEU A  84
GLY A 282
LEU A 293
 None
 0.72A 1gtiA-4fqjA:
undetectable		 1gtiA-4fqjA:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GSS_A_EAAA0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 4fqj HEMAGGLUTININ
(Influenza
B
virus) 		4 / 8 TYR A 202
VAL A 160
ILE A 243
GLY A 138
 None
 0.95A 2gssA-4fqjA:
undetectable		 2gssA-4fqjA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GSS_B_EAAB0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 4fqj HEMAGGLUTININ
(Influenza
B
virus) 		4 / 8 TYR A 202
VAL A 160
ILE A 243
GLY A 138
 None
 0.95A 2gssB-4fqjA:
undetectable		 2gssB-4fqjA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QEU_B_ACTB141_0
(PUTATIVE
CARBOXYMUCONOLACTONE
DECARBOXYLASE)		 4fqj HEMAGGLUTININ
(Influenza
B
virus) 		3 / 3 PRO A 134
ASN A 163
ARG A 262
 None
 0.91A 2qeuB-4fqjA:
undetectable		 2qeuB-4fqjA:
19.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YZQ_A_SAMA6075_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN PH1780)		 4fqj HEMAGGLUTININ
(Influenza
B
virus) 		5 / 12 ILE A 104
THR A 102
VAL A 245
ILE A 243
GLU A 233
 None
 1.26A 2yzqA-4fqjA:
undetectable		 2yzqA-4fqjA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DEU_B_SALB306_1
(TRANSCRIPTIONAL
REGULATOR SLYA)		 4fqj HEMAGGLUTININ
(Influenza
B
virus) 		4 / 6 THR A  47
THR A  49
ILE A 315
LEU A 293
 None
 0.93A 3deuB-4fqjA:
undetectable		 3deuB-4fqjA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N9J_A_EAAA210_1
(GLUTATHIONE
S-TRANSFERASE P)		 4fqj HEMAGGLUTININ
(Influenza
B
virus) 		4 / 8 TYR A 202
VAL A 160
ILE A 243
GLY A 138
 None
 0.97A 3n9jA-4fqjA:
undetectable		 3n9jA-4fqjA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR5_A_SRYA1860_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S12)		 4fqj HEMAGGLUTININ
(Influenza
B
virus) 		3 / 3 LYS A 304
PRO A 305
LYS A  33
 None
 1.37A 4dr5L-4fqjA:
undetectable		 4dr5L-4fqjA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DR6_A_SRYA1956_1
(16S RRNA
30S RIBOSOMAL
PROTEIN S12)		 4fqj HEMAGGLUTININ
(Influenza
B
virus) 		3 / 3 LYS A 304
PRO A 305
LYS A  33
 None
 1.43A 4dr6L-4fqjA:
undetectable		 4dr6L-4fqjA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_B_MRVB1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 4fqj HEMAGGLUTININ
(Influenza
B
virus) 		4 / 5 THR A  91
LEU A  67
THR A 186
MET A 248
 None
 1.48A 4mbsB-4fqjA:
undetectable		 4mbsB-4fqjA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_B_MRVB1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 4fqj HEMAGGLUTININ
(Influenza
B
virus) 		4 / 5 TYR A 260
LEU A  67
THR A 186
MET A 248
 None
 1.39A 4mbsB-4fqjA:
undetectable		 4mbsB-4fqjA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWW_A_ACAA18_2
(SCRFP-TAG,GP41)		 4fqj HEMAGGLUTININ
(Influenza
B
virus) 		3 / 3 LYS A 269
TRP A 271
SER A 120
 None
 0.97A 5nwwA-4fqjA:
undetectable		 5nwwA-4fqjA:
7.89