SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fqk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OF4_B_ACTB313_0 (NITROREDUCTASE)	4fqk	ANTIBODY CR8059 HEAVY CHAIN (Homo sapiens)	3 / 3	ALA E 168 VAL E 169 GLN E 171	None	0.63A	3of4B-4fqkE: undetectable	3of4B-4fqkE: 21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3V4T_H_ACTH502_0 (UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE)	4fqk	ANTIBODY CR8059 HEAVY CHAIN (Homo sapiens)	3 / 3	SER E 100 GLY E 100 GLN E 97	None	0.61A	3v4tH-4fqkE: undetectable	3v4tH-4fqkE: 20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VQR_A_ACTA1002_0 (PUTATIVE OXIDOREDUCTASE)	4fqk	ANTIBODY CR8059 HEAVY CHAIN (Homo sapiens)	4 / 6	ASP E 101 VAL E 96 ASP E 95 THR E 35	None	1.22A	3vqrA-4fqkE: undetectable	3vqrA-4fqkE: 19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VQR_B_ACTB1002_0 (PUTATIVE OXIDOREDUCTASE)	4fqk	ANTIBODY CR8059 HEAVY CHAIN (Homo sapiens)	4 / 5	ASP E 101 VAL E 96 ASP E 95 THR E 35	None	1.24A	3vqrB-4fqkE: undetectable	3vqrB-4fqkE: 19.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6DRZ_A_H8JA1206_0 (5HT2B RECEPTOR, BRIL CHIMERA)	4fqk	ANTIBODY CR8059 HEAVY CHAIN (Homo sapiens)	5 / 12	VAL E 207 THR E 205 VAL E 211 GLY E 118 VAL E 152	None	1.01A	6drzA-4fqkE: undetectable	6drzA-4fqkE: 18.03

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3OF4_B_ACTB313_0","NITROREDUCTASE","4fqk","ANTIBODY CR8059 HEAVY CHAIN","Homo sapiens",3,"ALA E 168;VAL E 169;GLN E 171","None","0.63A","3of4B-4fqkE:undetectable","3of4B-4fqkE:21.40"],["3V4T_H_ACTH502_0","UDP-N-ACETYLGLUCOSAMINE 1-CARBOXYVINYLTRANSFERASE","4fqk","ANTIBODY CR8059 HEAVY CHAIN","Homo sapiens",3,"SER E 100;GLY E 100;GLN E  97","None","0.61A","3v4tH-4fqkE:undetectable","3v4tH-4fqkE:20.37"],["3VQR_A_ACTA1002_0","PUTATIVE OXIDOREDUCTASE","4fqk","ANTIBODY CR8059 HEAVY CHAIN","Homo sapiens",4,"ASP E 101;VAL E  96;ASP E  95;THR E  35","None","1.22A","3vqrA-4fqkE:undetectable","3vqrA-4fqkE:19.87"],["3VQR_B_ACTB1002_0","PUTATIVE OXIDOREDUCTASE","4fqk","ANTIBODY CR8059 HEAVY CHAIN","Homo sapiens",4,"ASP E 101;VAL E  96;ASP E  95;THR E  35","None","1.24A","3vqrB-4fqkE:undetectable","3vqrB-4fqkE:19.87"],["6DRZ_A_H8JA1206_0","5HT2B RECEPTOR, BRIL CHIMERA","4fqk","ANTIBODY CR8059 HEAVY CHAIN","Homo sapiens",5,"VAL E 207;THR E 205;VAL E 211;GLY E 118;VAL E 152","None","1.01A","6drzA-4fqkE:undetectable","6drzA-4fqkE:18.03"]]