SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fqu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AQ7_B_AG2B4_1
(TRYPSIN
AERUGINOSIN 98-B)		 4fqu PUTATIVE GLUTATHIONE
TRANSFERASE
(Sphingobium
chlorophenolicum) 		5 / 8 HIS A 284
ASP A  11
SER A 288
GLY A  85
GLY A   2
 None
 1.27A 1aq7A-4fquA:
undetectable		 1aq7A-4fquA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIA_A_SAMA293_0
(GLYCINE
N-METHYLTRANSFERASE)		 4fqu PUTATIVE GLUTATHIONE
TRANSFERASE
(Sphingobium
chlorophenolicum) 		5 / 12 TYR A 285
ILE A 122
VAL A  77
SER A 288
HIS A 289
 None
 1.02A 1kiaA-4fquA:
undetectable		 1kiaA-4fquA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_A_CQAA403_0
(HISTAMINE
N-METHYLTRANSFERASE)		 4fqu PUTATIVE GLUTATHIONE
TRANSFERASE
(Sphingobium
chlorophenolicum) 		4 / 8 ASP A  35
GLY A  40
PHE A 149
ASP A 150
 None
 0.90A 2aouA-4fquA:
undetectable		 2aouA-4fquA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B7Z_B_MK1B200_1
(HIV-1 PROTEASE)		 4fqu PUTATIVE GLUTATHIONE
TRANSFERASE
(Sphingobium
chlorophenolicum) 		5 / 12 GLY A 101
ALA A 102
ASP A 103
ALA A 112
VAL A 108
 None
 1.07A 2b7zA-4fquA:
undetectable		 2b7zA-4fquA:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J0D_A_ERYA1498_0
(CYTOCHROME P450 3A4)		 4fqu PUTATIVE GLUTATHIONE
TRANSFERASE
(Sphingobium
chlorophenolicum) 		5 / 12 ARG A 143
ALA A  64
THR A 275
ARG A 230
GLU A 226
 None
 0.94A 2j0dA-4fquA:
undetectable		 2j0dA-4fquA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OUZ_A_C3DA999_1
(ESTROGEN RECEPTOR)		 4fqu PUTATIVE GLUTATHIONE
TRANSFERASE
(Sphingobium
chlorophenolicum) 		4 / 6 ALA A 227
ASP A 228
GLU A 226
ARG A 143
 None
 1.27A 2ouzA-4fquA:
undetectable		 2ouzA-4fquA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_G_CPFG1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 4fqu PUTATIVE GLUTATHIONE
TRANSFERASE
(Sphingobium
chlorophenolicum) 		3 / 3 ARG A  44
GLY A  43
SER A  98
 None
 0.58A 2xctB-4fquA:
undetectable		 2xctB-4fquA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_X_CPFX1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 4fqu PUTATIVE GLUTATHIONE
TRANSFERASE
(Sphingobium
chlorophenolicum) 		4 / 4 ARG A  44
GLY A  43
GLU A  41
SER A  98
 None
 1.43A 2xctS-4fquA:
undetectable
2xctU-4fquA:
undetectable		 2xctS-4fquA:
21.31
2xctU-4fquA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_1
(PROTEASE)		 4fqu PUTATIVE GLUTATHIONE
TRANSFERASE
(Sphingobium
chlorophenolicum) 		4 / 8 GLY A 101
ALA A 102
ASP A 103
PRO A 114
 None
 0.68A 3el0A-4fquA:
undetectable		 3el0A-4fquA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_A_CE3A303_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 4fqu PUTATIVE GLUTATHIONE
TRANSFERASE
(Sphingobium
chlorophenolicum) 		4 / 4 ASN A 180
SER A 138
SER A  28
ARG A  31
 None
 1.47A 3hlwA-4fquA:
0.0		 3hlwA-4fquA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HLW_B_CE3B304_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 4fqu PUTATIVE GLUTATHIONE
TRANSFERASE
(Sphingobium
chlorophenolicum) 		4 / 5 ASN A 180
SER A 138
SER A  28
ARG A  31
 None
 1.47A 3hlwB-4fquA:
undetectable		 3hlwB-4fquA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9F_F_LFXF0_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 4fqu PUTATIVE GLUTATHIONE
TRANSFERASE
(Sphingobium
chlorophenolicum) 		4 / 5 SER A  98
ARG A  44
GLY A  43
GLU A  41
 None
 1.14A 3k9fA-4fquA:
undetectable
3k9fB-4fquA:
undetectable
3k9fC-4fquA:
undetectable		 3k9fA-4fquA:
22.31
3k9fB-4fquA:
22.31
3k9fC-4fquA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9F_H_LFXH0_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 4fqu PUTATIVE GLUTATHIONE
TRANSFERASE
(Sphingobium
chlorophenolicum) 		4 / 6 SER A  98
ARG A  44
GLY A  43
GLU A  41
 None
 1.14A 3k9fA-4fquA:
undetectable
3k9fB-4fquA:
undetectable
3k9fD-4fquA:
undetectable		 3k9fA-4fquA:
22.31
3k9fB-4fquA:
22.31
3k9fD-4fquA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P73_A_ACTA275_0
(MHC RFP-Y CLASS I
ALPHA CHAIN)		 4fqu PUTATIVE GLUTATHIONE
TRANSFERASE
(Sphingobium
chlorophenolicum) 		3 / 3 ILE A 276
VAL A 236
ARG A 237
 None
 0.71A 3p73A-4fquA:
undetectable		 3p73A-4fquA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_A_ACTA1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 4fqu PUTATIVE GLUTATHIONE
TRANSFERASE
(Sphingobium
chlorophenolicum) 		4 / 5 GLY A 264
ALA A 267
GLY A 308
PRO A 307
 None
 0.86A 4u9uA-4fquA:
undetectable		 4u9uA-4fquA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_B_ACTB1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 4fqu PUTATIVE GLUTATHIONE
TRANSFERASE
(Sphingobium
chlorophenolicum) 		4 / 5 GLY A 264
ALA A 267
GLY A 308
PRO A 307
 None
 0.89A 4u9uB-4fquA:
undetectable		 4u9uB-4fquA:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJE_A_TOYA202_1
(AADB)		 4fqu PUTATIVE GLUTATHIONE
TRANSFERASE
(Sphingobium
chlorophenolicum) 		4 / 8 TYR A 160
ASP A 169
GLU A 226
ILE A 142
 None
 0.93A 4xjeA-4fquA:
undetectable		 4xjeA-4fquA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z3O_F_MFXF101_1
(DNA TOPOISOMERASE 4
SUBUNIT
B,PARE30-PARC55
FUSED TOPO IV FROM
S. PNEUMONIAE
E-SITE DNA)		 4fqu PUTATIVE GLUTATHIONE
TRANSFERASE
(Sphingobium
chlorophenolicum) 		4 / 5 ARG A  44
GLY A  43
GLU A  41
SER A  75
 None
 1.07A 4z3oA-4fquA:
undetectable
4z3oB-4fquA:
undetectable		 4z3oA-4fquA:
18.28
4z3oB-4fquA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_E_GFNE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 4fqu PUTATIVE GLUTATHIONE
TRANSFERASE
(Sphingobium
chlorophenolicum) 		4 / 7 ALA A 112
ARG A  31
GLY A  32
GLU A 140
 None
 0.95A 5btdA-4fquA:
undetectable
5btdB-4fquA:
undetectable
5btdC-4fquA:
undetectable		 5btdA-4fquA:
21.67
5btdB-4fquA:
21.69
5btdC-4fquA:
21.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 4fqu PUTATIVE GLUTATHIONE
TRANSFERASE
(Sphingobium
chlorophenolicum) 		4 / 7 ALA A 112
ARG A  31
GLY A  32
GLU A 140
 None
 0.96A 5btdA-4fquA:
undetectable
5btdC-4fquA:
undetectable
5btdD-4fquA:
undetectable		 5btdA-4fquA:
21.67
5btdC-4fquA:
21.67
5btdD-4fquA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_E_MFXE2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 4fqu PUTATIVE GLUTATHIONE
TRANSFERASE
(Sphingobium
chlorophenolicum) 		4 / 5 SER A  75
ARG A  44
GLY A  43
GLU A  41
 None
 0.98A 5cdqA-4fquA:
undetectable
5cdqB-4fquA:
undetectable
5cdqC-4fquA:
undetectable		 5cdqA-4fquA:
19.54
5cdqB-4fquA:
19.06
5cdqC-4fquA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_E_MFXE2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 4fqu PUTATIVE GLUTATHIONE
TRANSFERASE
(Sphingobium
chlorophenolicum) 		4 / 5 SER A  98
ARG A  44
GLY A  43
GLU A  41
 None
 0.93A 5cdqA-4fquA:
undetectable
5cdqB-4fquA:
undetectable
5cdqC-4fquA:
undetectable		 5cdqA-4fquA:
19.54
5cdqB-4fquA:
19.06
5cdqC-4fquA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_V_MFXV2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 4fqu PUTATIVE GLUTATHIONE
TRANSFERASE
(Sphingobium
chlorophenolicum) 		4 / 5 SER A  75
ARG A  44
GLY A  43
GLU A  41
 None
 0.97A 5cdqR-4fquA:
undetectable
5cdqS-4fquA:
undetectable
5cdqT-4fquA:
undetectable		 5cdqR-4fquA:
19.54
5cdqS-4fquA:
19.06
5cdqT-4fquA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDQ_V_MFXV2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 4fqu PUTATIVE GLUTATHIONE
TRANSFERASE
(Sphingobium
chlorophenolicum) 		4 / 5 SER A  98
ARG A  44
GLY A  43
GLU A  41
 None
 0.95A 5cdqR-4fquA:
undetectable
5cdqS-4fquA:
undetectable
5cdqT-4fquA:
undetectable		 5cdqR-4fquA:
19.54
5cdqS-4fquA:
19.06
5cdqT-4fquA:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CFS_A_TOYA203_1
(AAD(2''),GENTAMICIN
2''-NUCLEOTIDYLTRANS
FERASE,GENTAMICIN
RESISTANCE PROTEIN)		 4fqu PUTATIVE GLUTATHIONE
TRANSFERASE
(Sphingobium
chlorophenolicum) 		4 / 8 TYR A 160
ASP A 169
GLU A 226
ILE A 142
 None
 0.98A 5cfsA-4fquA:
1.9		 5cfsA-4fquA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMW_B_RBFB201_1
(GLYOXALASE/BLEOMYCIN
RESISANCE
PROTEIN/DIOXYGENASE)		 4fqu PUTATIVE GLUTATHIONE
TRANSFERASE
(Sphingobium
chlorophenolicum) 		4 / 7 VAL A 152
ARG A  44
GLU A  41
LEU A 125
 None
 1.11A 5umwB-4fquA:
undetectable
5umwE-4fquA:
undetectable		 5umwB-4fquA:
14.69
5umwE-4fquA:
14.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AK3_B_P2EB1201_1
(PROSTAGLANDIN E2
RECEPTOR EP3
SUBTYPE,SOLUBLE
CYTOCHROME B562)		 4fqu PUTATIVE GLUTATHIONE
TRANSFERASE
(Sphingobium
chlorophenolicum) 		4 / 5 PRO A 123
VAL A  59
GLY A  43
VAL A  74
 None
 0.99A 6ak3B-4fquA:
undetectable		 6ak3B-4fquA:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_E_GBME2001_1
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 4fqu PUTATIVE GLUTATHIONE
TRANSFERASE
(Sphingobium
chlorophenolicum) 		5 / 12 PHE A 232
ASN A 180
THR A 205
LEU A 179
SER A 268
 None
 1.40A 6baaE-4fquA:
2.7		 6baaE-4fquA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_F_GBMF2001_1
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 4fqu PUTATIVE GLUTATHIONE
TRANSFERASE
(Sphingobium
chlorophenolicum) 		5 / 12 PHE A 232
ASN A 180
THR A 205
LEU A 179
SER A 268
 None
 1.40A 6baaF-4fquA:
2.7		 6baaF-4fquA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_G_GBMG2001_1
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 4fqu PUTATIVE GLUTATHIONE
TRANSFERASE
(Sphingobium
chlorophenolicum) 		5 / 12 PHE A 232
ASN A 180
THR A 205
LEU A 179
SER A 268
 None
 1.41A 6baaG-4fquA:
2.7		 6baaG-4fquA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BAA_H_GBMH2001_1
(ATP-BINDING CASSETTE
SUB-FAMILY C MEMBER
8)		 4fqu PUTATIVE GLUTATHIONE
TRANSFERASE
(Sphingobium
chlorophenolicum) 		5 / 12 PHE A 232
ASN A 180
THR A 205
LEU A 179
SER A 268
 None
 1.41A 6baaH-4fquA:
2.7		 6baaH-4fquA:
11.08