SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fr2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA355_1
(PROTEIN (ADENOSINE
KINASE))		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		5 / 12 GLY A 145
ILE A 227
ALA A 254
GLY A 255
HIS A 267
 None
None
None
None
NI  A 501 (-3.4A)
 0.91A 1bx4A-4fr2A:
3.3		 1bx4A-4fr2A:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_H_ACTH3006_0
(BETA-CARBONIC
ANHYDRASE)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		4 / 6 GLN A 202
CYH A 285
ASP A 198
HIS A 281
 NI  A 501 (-2.8A)
None
NI  A 501 (-2.7A)
NI  A 501 (-3.6A)
 1.43A 1ekjG-4fr2A:
undetectable
1ekjH-4fr2A:
2.4		 1ekjG-4fr2A:
21.62
1ekjH-4fr2A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_H_ACTH3006_0
(BETA-CARBONIC
ANHYDRASE)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		4 / 6 GLN A 202
CYH A 285
VAL A 266
HIS A 281
 NI  A 501 (-2.8A)
None
None
NI  A 501 (-3.6A)
 1.37A 1ekjG-4fr2A:
undetectable
1ekjH-4fr2A:
2.4		 1ekjG-4fr2A:
21.62
1ekjH-4fr2A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_4
(HIV-1 PROTEASE)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		4 / 4 GLY A 108
ASP A 106
GLY A 147
THR A 142
 None
 1.00A 1hxbB-4fr2A:
undetectable		 1hxbB-4fr2A:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_B_SAMB302_1
(HEMK PROTEIN)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 ASP A 378
PHE A 383
ASN A 296
 None
 0.77A 1sg9B-4fr2A:
3.2		 1sg9B-4fr2A:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.75A 1v55A-4fr2A:
undetectable		 1v55A-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.75A 1v55N-4fr2A:
undetectable		 1v55N-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVS_B_MK1B902_1
(POL POLYPROTEIN)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		5 / 12 LEU A 137
GLY A 110
ALA A 111
VAL A  72
ILE A  96
 None
 0.88A 2avsA-4fr2A:
undetectable		 2avsA-4fr2A:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_F_SAMF301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		5 / 12 GLY A 274
LEU A 273
ASN A 360
ALA A 361
ALA A 367
 None
 1.04A 2bm9F-4fr2A:
3.0		 2bm9F-4fr2A:
19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.73A 2eikA-4fr2A:
undetectable		 2eikA-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.71A 2y69A-4fr2A:
1.2		 2y69A-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.74A 2y69N-4fr2A:
1.4		 2y69N-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.74A 2zxwA-4fr2A:
1.2		 2zxwA-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.71A 3abkA-4fr2A:
undetectable		 3abkA-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.67A 3abkN-4fr2A:
1.4		 3abkN-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.77A 3ablA-4fr2A:
undetectable		 3ablA-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.79A 3ablN-4fr2A:
undetectable		 3ablN-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.73A 3abmA-4fr2A:
undetectable		 3abmA-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.71A 3ag1A-4fr2A:
1.3		 3ag1A-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.74A 3ag1N-4fr2A:
undetectable		 3ag1N-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.67A 3ag2A-4fr2A:
undetectable		 3ag2A-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.71A 3ag2N-4fr2A:
1.3		 3ag2N-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.71A 3ag3A-4fr2A:
1.4		 3ag3A-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.72A 3ag3N-4fr2A:
0.8		 3ag3N-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.71A 3ag4A-4fr2A:
undetectable		 3ag4A-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.76A 3ag4N-4fr2A:
undetectable		 3ag4N-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI8_B_HNQB255_1
(CATHEPSIN B)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		4 / 6 GLN A 202
GLY A 145
HIS A 267
CYH A 285
 NI  A 501 (-2.8A)
None
NI  A 501 (-3.4A)
None
 0.96A 3ai8B-4fr2A:
undetectable		 3ai8B-4fr2A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI8_B_HNQB255_1
(CATHEPSIN B)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		4 / 6 GLN A 202
GLY A 145
HIS A 271
CYH A 285
 NI  A 501 (-2.8A)
None
None
None
 1.35A 3ai8B-4fr2A:
undetectable		 3ai8B-4fr2A:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.73A 3asnA-4fr2A:
1.1		 3asnA-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.74A 3asnN-4fr2A:
undetectable		 3asnN-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.73A 3asoA-4fr2A:
1.0		 3asoA-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.75A 3asoN-4fr2A:
undetectable		 3asoN-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVD_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.77A 3bvdA-4fr2A:
undetectable		 3bvdA-4fr2A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_A_CUA1023_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.72A 3dtuA-4fr2A:
undetectable		 3dtuA-4fr2A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_C_CUC569_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.72A 3dtuC-4fr2A:
undetectable		 3dtuC-4fr2A:
22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_2
(HIV-1 PROTEASE)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		4 / 4 GLY A 108
ASP A 106
GLY A 147
THR A 142
 None
 1.01A 3k4vC-4fr2A:
undetectable		 3k4vC-4fr2A:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU5_B_478B401_2
(PROTEASE)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		5 / 12 LEU A 137
GLY A 110
ALA A 111
VAL A  37
ILE A  96
 None
 1.14A 3nu5B-4fr2A:
undetectable		 3nu5B-4fr2A:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_C_478C200_1
(HIV-1 PROTEASE)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		5 / 9 LEU A 137
GLY A 110
ALA A 111
VAL A  72
ILE A  96
 None
 0.91A 3oxvC-4fr2A:
undetectable		 3oxvC-4fr2A:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWM_B_017B402_1
(PROTEASE)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		5 / 12 LEU A 137
GLY A 110
ALA A 111
VAL A  37
ILE A  96
 None
 1.03A 3pwmA-4fr2A:
undetectable		 3pwmA-4fr2A:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R2J_C_NIOC311_1
(ALPHA/BETA-HYDROLASE
-LIKE PROTEIN)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		5 / 12 LEU A 263
ASP A 198
HIS A 281
HIS A 267
ALA A 254
 None
NI  A 501 (-2.7A)
NI  A 501 (-3.6A)
NI  A 501 (-3.4A)
None
 1.20A 3r2jC-4fr2A:
3.8		 3r2jC-4fr2A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S33_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.75A 3s33A-4fr2A:
0.0		 3s33A-4fr2A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S39_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.74A 3s39A-4fr2A:
0.7		 3s39A-4fr2A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3A_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.77A 3s3aA-4fr2A:
undetectable		 3s3aA-4fr2A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3B_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.81A 3s3bA-4fr2A:
undetectable		 3s3bA-4fr2A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3C_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.76A 3s3cA-4fr2A:
undetectable		 3s3cA-4fr2A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3D_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.73A 3s3dA-4fr2A:
undetectable		 3s3dA-4fr2A:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SGL_A_SAMA692_0
(TRNA
5-METHYLAMINOMETHYL-
2-THIOURIDINE
BIOSYNTHESIS
BIFUNCTIONAL PROTEIN
MNMC)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		5 / 12 GLU A 149
GLY A 147
GLY A 145
ASN A 179
GLY A 255
 None
 1.06A 3sglA-4fr2A:
undetectable		 3sglA-4fr2A:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_1
(MNMC2)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		4 / 6 HIS A 271
ASP A 378
ASP A 364
ASN A 370
 None
 1.30A 3vywA-4fr2A:
undetectable		 3vywA-4fr2A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.74A 3wg7N-4fr2A:
undetectable		 3wg7N-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_A_CUA604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.74A 3x2qA-4fr2A:
1.3		 3x2qA-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_2
(SEPIAPTERIN
REDUCTASE)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 LEU A 150
MET A 252
ASP A 211
 None
 0.55A 4j7xB-4fr2A:
3.1		 4j7xB-4fr2A:
24.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QCK_A_ASDA404_1
(3-KETOSTEROID-9-ALPH
A-MONOOXYGENASE
OXYGENASE SUBUNIT)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		5 / 12 ASN A  14
VAL A 176
ALA A 139
ASN A 179
GLY A 255
 None
 1.32A 4qckA-4fr2A:
undetectable		 4qckA-4fr2A:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V20_A_ACTA1444_0
(CELLOBIOHYDROLASE)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		4 / 5 GLY A 101
THR A 143
HIS A 105
GLY A 147
 None
 1.12A 4v20A-4fr2A:
undetectable		 4v20A-4fr2A:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.73A 5b1aA-4fr2A:
undetectable		 5b1aA-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.77A 5b1aN-4fr2A:
undetectable		 5b1aN-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.69A 5b1bA-4fr2A:
undetectable		 5b1bA-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.73A 5b1bN-4fr2A:
undetectable		 5b1bN-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.68A 5b3sA-4fr2A:
undetectable		 5b3sA-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.69A 5b3sN-4fr2A:
undetectable		 5b3sN-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.71A 5iy5A-4fr2A:
undetectable		 5iy5A-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.72A 5iy5N-4fr2A:
undetectable		 5iy5N-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_A_ADNA401_1
(ADENOSINE KINASE)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		5 / 12 GLY A 145
ILE A 227
ALA A 254
GLY A 255
HIS A 267
 None
None
None
None
NI  A 501 (-3.4A)
 0.88A 5kb6A-4fr2A:
3.6		 5kb6A-4fr2A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_B_ADNB401_1
(ADENOSINE KINASE)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		5 / 12 GLY A 145
ILE A 227
ALA A 254
GLY A 255
HIS A 267
 None
None
None
None
NI  A 501 (-3.4A)
 0.90A 5kb6B-4fr2A:
2.5		 5kb6B-4fr2A:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA303_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 GLU A 294
TYR A 295
ARG A 372
 None
 0.80A 5uunA-4fr2A:
1.0		 5uunA-4fr2A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_B_ACTB305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 GLU A 294
TYR A 295
ARG A 372
 None
 0.59A 5uunB-4fr2A:
undetectable		 5uunB-4fr2A:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.73A 5w97a-4fr2A:
undetectable		 5w97a-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.67A 5waua-4fr2A:
1.4		 5waua-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.67A 5x19A-4fr2A:
undetectable		 5x19A-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.67A 5x19N-4fr2A:
undetectable		 5x19N-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.65A 5x1bA-4fr2A:
undetectable		 5x1bA-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.61A 5x1bN-4fr2A:
undetectable		 5x1bN-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.70A 5x1fA-4fr2A:
undetectable		 5x1fA-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.67A 5x1fN-4fr2A:
undetectable		 5x1fN-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.73A 5xdqA-4fr2A:
1.2		 5xdqA-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.74A 5xdqN-4fr2A:
undetectable		 5xdqN-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.69A 5xdxA-4fr2A:
undetectable		 5xdxA-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.71A 5xdxN-4fr2A:
undetectable		 5xdxN-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.76A 5z86A-4fr2A:
0.8		 5z86A-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.77A 5zcoA-4fr2A:
undetectable		 5zcoA-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8F_A_ACTA803_0
(UNCHARACTERIZED
PROTEIN)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 GLU A 294
LEU A 297
ARG A 372
 None
 0.81A 6d8fA-4fr2A:
undetectable		 6d8fA-4fr2A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GIQ_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.68A 6giqa-4fr2A:
undetectable		 6giqa-4fr2A:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.70A 6hu9a-4fr2A:
0.6		 6hu9a-4fr2A:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_M_CUM601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.75A 6hu9m-4fr2A:
undetectable		 6hu9m-4fr2A:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IFT_A_SAMA301_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE A)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		5 / 12 LEU A  56
ILE A 138
ASP A 180
LEU A 183
VAL A 176
 None
 1.02A 6iftA-4fr2A:
undetectable		 6iftA-4fr2A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.70A 6nknA-4fr2A:
undetectable		 6nknA-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.72A 6nknN-4fr2A:
undetectable		 6nknN-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.65A 6nmfA-4fr2A:
undetectable		 6nmfA-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.69A 6nmfN-4fr2A:
undetectable		 6nmfN-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.70A 6nmpA-4fr2A:
undetectable		 6nmpA-4fr2A:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 4fr2 1,3-PROPANEDIOL
DEHYDROGENASE
(Oenococcus
oeni) 		3 / 3 HIS A 267
HIS A 281
HIS A 271
 NI  A 501 (-3.4A)
NI  A 501 (-3.6A)
None
 0.74A 6nmpN-4fr2A:
undetectable		 6nmpN-4fr2A:
22.06