SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fr9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YAJ_G_BEZG3385_0 (CES1 PROTEIN)	4fr9	UNCHARACTERIZED PROTEIN (Bacteroides fragilis)	3 / 3	SER A 106 VAL A 131 LEU A 141	None	0.73A	1yajG-4fr9A: undetectable	1yajG-4fr9A: 14.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CTJ_C_SAMC1263_0 (NON-STRUCTURAL PROTEIN 5)	4fr9	UNCHARACTERIZED PROTEIN (Bacteroides fragilis)	5 / 12	GLY A 146 GLY A 148 GLU A 105 VAL A 113 ILE A 92	None	0.91A	4ctjC-4fr9A: undetectable	4ctjC-4fr9A: 21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EC8_C_SAMC4000_0 (GENOME POLYPROTEIN)	4fr9	UNCHARACTERIZED PROTEIN (Bacteroides fragilis)	5 / 12	GLY A 146 GLY A 148 GLU A 105 VAL A 113 ILE A 92	None	0.86A	5ec8C-4fr9A: undetectable	5ec8C-4fr9A: 21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WZ1_C_SAMC601_0 (NS5 METHYLTRANSFERASE)	4fr9	UNCHARACTERIZED PROTEIN (Bacteroides fragilis)	5 / 12	GLY A 146 GLY A 148 GLU A 105 VAL A 113 ILE A 92	None	0.99A	5wz1C-4fr9A: undetectable	5wz1C-4fr9A: 18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WZ1_D_SAMD601_0 (NS5 METHYLTRANSFERASE)	4fr9	UNCHARACTERIZED PROTEIN (Bacteroides fragilis)	5 / 12	GLY A 146 GLY A 148 GLU A 105 VAL A 113 ILE A 92	None	1.00A	5wz1D-4fr9A: undetectable	5wz1D-4fr9A: 18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WZ1_E_SAME601_0 (NS5 METHYLTRANSFERASE)	4fr9	UNCHARACTERIZED PROTEIN (Bacteroides fragilis)	5 / 12	GLY A 146 GLY A 148 GLU A 105 VAL A 113 ILE A 92	None	1.00A	5wz1E-4fr9A: undetectable	5wz1E-4fr9A: 18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WZ1_F_SAMF601_0 (NS5 METHYLTRANSFERASE)	4fr9	UNCHARACTERIZED PROTEIN (Bacteroides fragilis)	5 / 12	GLY A 146 GLY A 148 GLU A 105 VAL A 113 ILE A 92	None	1.01A	5wz1F-4fr9A: undetectable	5wz1F-4fr9A: 18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WZ1_G_SAMG601_0 (NS5 METHYLTRANSFERASE)	4fr9	UNCHARACTERIZED PROTEIN (Bacteroides fragilis)	5 / 12	GLY A 146 GLY A 148 GLU A 105 VAL A 113 ILE A 92	None	0.99A	5wz1G-4fr9A: undetectable	5wz1G-4fr9A: 18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WZ1_H_SAMH601_0 (NS5 METHYLTRANSFERASE)	4fr9	UNCHARACTERIZED PROTEIN (Bacteroides fragilis)	5 / 12	GLY A 146 GLY A 148 GLU A 105 VAL A 113 ILE A 92	None	1.01A	5wz1H-4fr9A: undetectable	5wz1H-4fr9A: 18.59

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1YAJ_G_BEZG3385_0","CES1 PROTEIN","4fr9","UNCHARACTERIZED PROTEIN","Bacteroides fragilis",3,"SER A 106;VAL A 131;LEU A 141","None","0.73A","1yajG-4fr9A:undetectable","1yajG-4fr9A:14.12"],["4CTJ_C_SAMC1263_0","NON-STRUCTURAL PROTEIN 5","4fr9","UNCHARACTERIZED PROTEIN","Bacteroides fragilis",5,"GLY A 146;GLY A 148;GLU A 105;VAL A 113;ILE A  92","None","0.91A","4ctjC-4fr9A:undetectable","4ctjC-4fr9A:21.09"],["5EC8_C_SAMC4000_0","GENOME POLYPROTEIN","4fr9","UNCHARACTERIZED PROTEIN","Bacteroides fragilis",5,"GLY A 146;GLY A 148;GLU A 105;VAL A 113;ILE A  92","None","0.86A","5ec8C-4fr9A:undetectable","5ec8C-4fr9A:21.09"],["5WZ1_C_SAMC601_0","NS5 METHYLTRANSFERASE","4fr9","UNCHARACTERIZED PROTEIN","Bacteroides fragilis",5,"GLY A 146;GLY A 148;GLU A 105;VAL A 113;ILE A  92","None","0.99A","5wz1C-4fr9A:undetectable","5wz1C-4fr9A:18.59"],["5WZ1_D_SAMD601_0","NS5 METHYLTRANSFERASE","4fr9","UNCHARACTERIZED PROTEIN","Bacteroides fragilis",5,"GLY A 146;GLY A 148;GLU A 105;VAL A 113;ILE A  92","None","1.00A","5wz1D-4fr9A:undetectable","5wz1D-4fr9A:18.59"],["5WZ1_E_SAME601_0","NS5 METHYLTRANSFERASE","4fr9","UNCHARACTERIZED PROTEIN","Bacteroides fragilis",5,"GLY A 146;GLY A 148;GLU A 105;VAL A 113;ILE A  92","None","1.00A","5wz1E-4fr9A:undetectable","5wz1E-4fr9A:18.59"],["5WZ1_F_SAMF601_0","NS5 METHYLTRANSFERASE","4fr9","UNCHARACTERIZED PROTEIN","Bacteroides fragilis",5,"GLY A 146;GLY A 148;GLU A 105;VAL A 113;ILE A  92","None","1.01A","5wz1F-4fr9A:undetectable","5wz1F-4fr9A:18.59"],["5WZ1_G_SAMG601_0","NS5 METHYLTRANSFERASE","4fr9","UNCHARACTERIZED PROTEIN","Bacteroides fragilis",5,"GLY A 146;GLY A 148;GLU A 105;VAL A 113;ILE A  92","None","0.99A","5wz1G-4fr9A:undetectable","5wz1G-4fr9A:18.59"],["5WZ1_H_SAMH601_0","NS5 METHYLTRANSFERASE","4fr9","UNCHARACTERIZED PROTEIN","Bacteroides fragilis",5,"GLY A 146;GLY A 148;GLU A 105;VAL A 113;ILE A  92","None","1.01A","5wz1H-4fr9A:undetectable","5wz1H-4fr9A:18.59"]]