SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4frt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DVT_A_FLPA125_1
(TRANSTHYRETIN)		 4frt PROBABLE PORIN
(Pseudomonas
aeruginosa) 		4 / 8 LEU A  40
ALA A   8
LEU A  10
LEU A 360
 None
 0.77A 1dvtA-4frtA:
undetectable
1dvtB-4frtA:
undetectable		 1dvtA-4frtA:
13.88
1dvtB-4frtA:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		 4frt PROBABLE PORIN
(Pseudomonas
aeruginosa) 		5 / 12 GLY A 283
THR A 284
LEU A  60
VAL A 153
THR A 123
 None
 1.32A 1jipA-4frtA:
undetectable		 1jipA-4frtA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_P_CHDP1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4frt PROBABLE PORIN
(Pseudomonas
aeruginosa) 		4 / 5 PHE A 120
PHE A 130
LEU A 150
PHE A 187
 None
 1.32A 2y69P-4frtA:
undetectable
2y69W-4frtA:
undetectable		 2y69P-4frtA:
20.34
2y69W-4frtA:
12.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A27_A_SAMA250_1
(UNCHARACTERIZED
PROTEIN MJ1557)		 4frt PROBABLE PORIN
(Pseudomonas
aeruginosa) 		3 / 3 MET A 272
GLU A 344
ASN A 378
 None
 1.08A 3a27A-4frtA:
undetectable		 3a27A-4frtA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4frt PROBABLE PORIN
(Pseudomonas
aeruginosa) 		4 / 5 PHE A 120
PHE A 130
LEU A 150
PHE A 187
 None
 1.32A 3abmP-4frtA:
undetectable
3abmW-4frtA:
undetectable		 3abmP-4frtA:
20.34
3abmW-4frtA:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_B_BCZB1001_0
(NEURAMINIDASE)		 4frt PROBABLE PORIN
(Pseudomonas
aeruginosa) 		5 / 12 ASP A 157
ARG A 156
ARG A  64
ALA A 282
GLU A 162
 None
 1.48A 3k39B-4frtA:
undetectable		 3k39B-4frtA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_C_BCZC1001_0
(NEURAMINIDASE)		 4frt PROBABLE PORIN
(Pseudomonas
aeruginosa) 		5 / 12 ASP A 157
ARG A 156
ARG A  64
ALA A 282
GLU A 162
 None
 1.47A 3k39C-4frtA:
undetectable		 3k39C-4frtA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_D_BCZD1001_0
(NEURAMINIDASE)		 4frt PROBABLE PORIN
(Pseudomonas
aeruginosa) 		5 / 12 ASP A 157
ARG A 156
ARG A  64
ALA A 282
GLU A 162
 None
 1.49A 3k39D-4frtA:
undetectable		 3k39D-4frtA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_I_BCZI1001_0
(NEURAMINIDASE)		 4frt PROBABLE PORIN
(Pseudomonas
aeruginosa) 		5 / 12 ASP A 157
ARG A 156
ARG A  64
ALA A 282
GLU A 162
 None
 1.49A 3k39I-4frtA:
undetectable		 3k39I-4frtA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_J_BCZJ1001_0
(NEURAMINIDASE)		 4frt PROBABLE PORIN
(Pseudomonas
aeruginosa) 		5 / 12 ASP A 157
ARG A 156
ARG A  64
ALA A 282
GLU A 162
 None
 1.47A 3k39J-4frtA:
undetectable		 3k39J-4frtA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_K_BCZK1001_0
(NEURAMINIDASE)		 4frt PROBABLE PORIN
(Pseudomonas
aeruginosa) 		5 / 12 ASP A 157
ARG A 156
ARG A  64
ALA A 282
GLU A 162
 None
 1.47A 3k39K-4frtA:
undetectable		 3k39K-4frtA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K39_L_BCZL1001_0
(NEURAMINIDASE)		 4frt PROBABLE PORIN
(Pseudomonas
aeruginosa) 		5 / 12 ASP A 157
ARG A 156
ARG A  64
ALA A 282
GLU A 162
 None
 1.48A 3k39L-4frtA:
undetectable		 3k39L-4frtA:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CP3_B_RBTB1129_1
(B-CELL LYMPHOMA 6
PROTEIN)		 4frt PROBABLE PORIN
(Pseudomonas
aeruginosa) 		4 / 7 LEU A 252
ARG A 271
GLY A 268
TYR A 269
 None
 0.95A 4cp3A-4frtA:
undetectable
4cp3B-4frtA:
undetectable		 4cp3A-4frtA:
15.38
4cp3B-4frtA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P6X_G_HCYG900_2
(GLUCOCORTICOID
RECEPTOR)		 4frt PROBABLE PORIN
(Pseudomonas
aeruginosa) 		3 / 3 LEU A 367
MET A 324
TYR A 353
 None
 0.88A 4p6xG-4frtA:
undetectable		 4p6xG-4frtA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA811_0
(GEPHYRIN)		 4frt PROBABLE PORIN
(Pseudomonas
aeruginosa) 		3 / 3 LEU A  39
LEU A  58
ARG A  41
 None
 0.69A 6fgcA-4frtA:
undetectable		 6fgcA-4frtA:
21.33