SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4frw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2503_0
(FERROCHELATASE)		 4frw POLIOVIRUS
RECEPTOR-RELATED
PROTEIN 4
(Homo
sapiens) 		4 / 4 LEU A  50
PRO A  51
LEU A 141
ARG A 142
 None
 1.29A 1hrkB-4frwA:
undetectable		 1hrkB-4frwA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_A_CHDA703_0
(FERROCHELATASE)		 4frw POLIOVIRUS
RECEPTOR-RELATED
PROTEIN 4
(Homo
sapiens) 		4 / 4 LEU A  50
PRO A  51
LEU A 141
ARG A 142
 None
 1.21A 2hrcA-4frwA:
undetectable		 2hrcA-4frwA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1604_0
(FERROCHELATASE)		 4frw POLIOVIRUS
RECEPTOR-RELATED
PROTEIN 4
(Homo
sapiens) 		4 / 4 LEU A  50
PRO A  51
LEU A 141
ARG A 142
 None
 1.32A 2hrcB-4frwA:
undetectable		 2hrcB-4frwA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4frw POLIOVIRUS
RECEPTOR-RELATED
PROTEIN 4
(Homo
sapiens) 		4 / 4 LEU A  50
PRO A  51
LEU A 141
ARG A 142
 None
 1.27A 2pnjB-4frwA:
undetectable		 2pnjB-4frwA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB927_0
(FERROCHELATASE)		 4frw POLIOVIRUS
RECEPTOR-RELATED
PROTEIN 4
(Homo
sapiens) 		3 / 3 LEU A  50
PRO A  51
ARG A 142
 None
 0.64A 2qd4B-4frwA:
undetectable		 2qd4B-4frwA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCO_B_CHDB1_0
(FERROCHELATASE,
MITOCHONDRIAL)		 4frw POLIOVIRUS
RECEPTOR-RELATED
PROTEIN 4
(Homo
sapiens) 		4 / 4 LEU A  50
PRO A  51
LEU A 141
ARG A 142
 None
 1.29A 3hcoB-4frwA:
undetectable		 3hcoB-4frwA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_0
(METHYLTRANSFERASE
WBDD)		 4frw POLIOVIRUS
RECEPTOR-RELATED
PROTEIN 4
(Homo
sapiens) 		5 / 12 GLN A  77
ALA A  93
LEU A  79
VAL A  90
HIS A  89
 None
 1.24A 4azsA-4frwA:
undetectable		 4azsA-4frwA:
18.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z91_F_4LEF401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 4frw POLIOVIRUS
RECEPTOR-RELATED
PROTEIN 4
(Homo
sapiens) 		4 / 7 LEU A 210
THR A 191
THR A 185
LEU A 221
 None
 0.96A 4z91F-4frwA:
undetectable
4z91G-4frwA:
3.4
4z91H-4frwA:
undetectable
4z91I-4frwA:
undetectable
4z91J-4frwA:
undetectable		 4z91F-4frwA:
23.23
4z91G-4frwA:
23.23
4z91H-4frwA:
23.23
4z91I-4frwA:
23.23
4z91J-4frwA:
23.23