SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4fsj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RV7_B_AB1B1001_1
(PROTEASE)		 4fsj CAPSID PROTEIN BETA
(Flock
House
virus) 		5 / 11 ALA A 107
ILE A 236
THR A 178
PRO A 177
ALA A 311
 None
 1.12A 1rv7A-4fsjA:
undetectable
1rv7B-4fsjA:
undetectable		 1rv7A-4fsjA:
14.57
1rv7B-4fsjA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VH3_B_DAHB2_1
(RANASMURFIN)		 4fsj CAPSID PROTEIN BETA
(Flock
House
virus) 		4 / 8 SER A  94
GLY A  83
SER A 170
ALA A 169
 None
 0.79A 2vh3B-4fsjA:
undetectable		 2vh3B-4fsjA:
16.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA150_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 4fsj CAPSID PROTEIN BETA
(Flock
House
virus) 		5 / 12 GLN A 274
THR A 199
VAL A 200
VAL A 288
ILE A 259
 None
 1.04A 3em0A-4fsjA:
undetectable		 3em0A-4fsjA:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EK1_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 4fsj CAPSID PROTEIN BETA
(Flock
House
virus) 		5 / 9 TYR A 321
THR A 118
VAL A 289
ASP A  97
VAL A 121
 None
 1.46A 4ek1B-4fsjA:
undetectable		 4ek1B-4fsjA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_SAMA401_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 4fsj CAPSID PROTEIN BETA
(Flock
House
virus) 		5 / 12 LEU A  67
GLY A  83
GLY A  81
PRO A  80
VAL A  92
 None
 0.97A 4gc9A-4fsjA:
undetectable		 4gc9A-4fsjA:
21.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JLT_A_8PRA505_1
(CYTOCHROME P450 2B4)		 4fsj CAPSID PROTEIN BETA
(Flock
House
virus) 		4 / 8 ILE A 113
ILE A 175
ALA A 311
VAL A 301
 None
 0.69A 4jltA-4fsjA:
undetectable		 4jltA-4fsjA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K7G_B_ACTB902_0
(3-HYDROXYPROLINE
DEHYDRATSE)		 4fsj CAPSID PROTEIN BETA
(Flock
House
virus) 		4 / 7 ASP A  79
PRO A  73
SER A 170
TRP A 316
 None
 1.25A 4k7gB-4fsjA:
undetectable		 4k7gB-4fsjA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 4fsj CAPSID PROTEIN BETA
(Flock
House
virus) 		5 / 12 PRO A 119
THR A 118
GLY A 287
GLY A 290
ALA A 284
 None
 0.97A 5c0oG-4fsjA:
undetectable		 5c0oG-4fsjA:
21.08