SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '4ftd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_A_DVAA6_0
(GRAMICIDIN A)		 4ftd UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		3 / 3 ALA A 362
VAL A 323
TRP A 334
 None
 0.81A 1av2A-4ftdA:
undetectable
1av2B-4ftdA:
undetectable		 1av2A-4ftdA:
2.43
1av2B-4ftdA:
2.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AV2_D_DVAD6_0
(GRAMICIDIN A)		 4ftd UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		3 / 3 TRP A 334
ALA A 362
VAL A 323
 None
 0.90A 1av2C-4ftdA:
undetectable
1av2D-4ftdA:
undetectable		 1av2C-4ftdA:
2.43
1av2D-4ftdA:
2.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_C_DVAC6_0
(GRAMICIDIN A)		 4ftd UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		3 / 3 ALA A 362
VAL A 323
TRP A 334
 None
 0.86A 1c4dC-4ftdA:
undetectable
1c4dD-4ftdA:
undetectable		 1c4dC-4ftdA:
2.43
1c4dD-4ftdA:
2.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD6_0
(GRAMICIDIN A)		 4ftd UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		3 / 3 TRP A 334
ALA A 270
VAL A 323
 None
 0.93A 1c4dC-4ftdA:
undetectable
1c4dD-4ftdA:
undetectable		 1c4dC-4ftdA:
2.43
1c4dD-4ftdA:
2.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_A_EAAA224_1
(GLUTATHIONE
TRANSFERASE)		 4ftd UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		5 / 12 GLY A 460
LEU A 423
LEU A 391
ALA A 162
PHE A 453
 None
 1.22A 1gseA-4ftdA:
undetectable		 1gseA-4ftdA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GX9_A_REAA1163_1
(BETA-LACTOGLOBULIN)		 4ftd UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		5 / 11 ILE A 238
GLU A 242
ILE A 251
VAL A 295
PHE A 284
 None
 1.31A 1gx9A-4ftdA:
undetectable		 1gx9A-4ftdA:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN0_B_T44B602_1
(TRANSTHYRETIN)		 4ftd UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 7 LYS A  42
LEU A  44
GLU A  55
LEU A  91
 None
 1.10A 1sn0B-4ftdA:
3.3
1sn0D-4ftdA:
undetectable		 1sn0B-4ftdA:
13.53
1sn0D-4ftdA:
13.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_A_DVAA6_0
(GRAMICIDIN D)		 4ftd UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		3 / 3 ALA A 362
VAL A 323
TRP A 334
 None
 0.85A 1w5uA-4ftdA:
undetectable
1w5uB-4ftdA:
undetectable		 1w5uA-4ftdA:
2.43
1w5uB-4ftdA:
2.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_B_DVAB6_0
(GRAMICIDIN D)		 4ftd UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		3 / 3 TRP A 334
ALA A 362
VAL A 323
 None
 0.87A 1w5uA-4ftdA:
undetectable
1w5uB-4ftdA:
undetectable		 1w5uA-4ftdA:
2.43
1w5uB-4ftdA:
2.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W5U_D_DVAD8_0
(GRAMICIDIN D)		 4ftd UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		3 / 3 VAL A 339
VAL A 361
TRP A 334
 None
 0.95A 1w5uC-4ftdA:
undetectable
1w5uD-4ftdA:
undetectable		 1w5uC-4ftdA:
2.43
1w5uD-4ftdA:
2.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_A_PXLA1003_1
(PYRIDOXINE KINASE)		 4ftd UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 8 VAL A 223
LEU A 225
PRO A 183
HIS A 184
 None
 1.06A 2ddwA-4ftdA:
undetectable		 2ddwA-4ftdA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA6_0
(GRAMICIDIN D)		 4ftd UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		3 / 3 ALA A 362
VAL A 323
TRP A 334
 None
 0.96A 2izqA-4ftdA:
undetectable
2izqB-4ftdA:
undetectable		 2izqA-4ftdA:
2.43
2izqB-4ftdA:
2.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_A_DVAA8_0
(GRAMICIDIN D)		 4ftd UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		3 / 3 VAL A 361
TRP A 334
VAL A 339
 None
 0.89A 2izqA-4ftdA:
undetectable
2izqB-4ftdA:
undetectable		 2izqA-4ftdA:
2.43
2izqB-4ftdA:
2.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IZQ_D_DVAD6_0
(GRAMICIDIN D)		 4ftd UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		3 / 3 TRP A 334
ALA A 362
VAL A 323
 None
 0.83A 2izqC-4ftdA:
undetectable
2izqD-4ftdA:
undetectable		 2izqC-4ftdA:
2.43
2izqD-4ftdA:
2.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XN7_A_T44A1355_1
(THYROXINE-BINDING
GLOBULIN)		 4ftd UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		5 / 10 LEU A 185
LEU A 201
SER A 226
LEU A 225
LEU A 170
 None
 1.05A 2xn7A-4ftdA:
undetectable
2xn7B-4ftdA:
undetectable		 2xn7A-4ftdA:
23.28
2xn7B-4ftdA:
7.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_A_SALA3005_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 4ftd UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 8 ASN A 430
GLN A 434
ALA A 433
SER A 455
 None
 1.04A 3kp6A-4ftdA:
undetectable		 3kp6A-4ftdA:
16.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB6_0
(GRAMICIDIN D)		 4ftd UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		3 / 3 TRP A 334
ALA A 362
VAL A 323
 None
 0.91A 3l8lA-4ftdA:
undetectable
3l8lB-4ftdA:
undetectable		 3l8lA-4ftdA:
2.43
3l8lB-4ftdA:
4.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_B_DVAB8_0
(GRAMICIDIN D)		 4ftd UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		3 / 3 VAL A 339
VAL A 361
TRP A 334
 None
 0.91A 3l8lA-4ftdA:
undetectable
3l8lB-4ftdA:
undetectable		 3l8lA-4ftdA:
2.43
3l8lB-4ftdA:
4.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD6_0
(GRAMICIDIN D)		 4ftd UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		3 / 3 TRP A 334
ALA A 362
VAL A 323
 None
 0.84A 3l8lC-4ftdA:
undetectable
3l8lD-4ftdA:
undetectable		 3l8lC-4ftdA:
2.43
3l8lD-4ftdA:
4.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L8L_D_DVAD8_0
(GRAMICIDIN D)		 4ftd UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		3 / 3 VAL A 339
VAL A 361
TRP A 334
 None
 0.89A 3l8lC-4ftdA:
undetectable
3l8lD-4ftdA:
undetectable		 3l8lC-4ftdA:
2.43
3l8lD-4ftdA:
4.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3POC_B_ACRB665_1
(ALPHA-GLUCOSIDASE)		 4ftd UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 6 GLU A 370
ASP A 447
ASP A 442
LYS A 441
 None
 1.17A 3pocB-4ftdA:
undetectable		 3pocB-4ftdA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC610_0
(GBAA_1210 PROTEIN)		 4ftd UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		3 / 3 ASN A 428
ALA A 431
ARG A 456
 None
 0.81A 3tj7C-4ftdA:
undetectable
3tj7D-4ftdA:
undetectable		 3tj7C-4ftdA:
17.67
3tj7D-4ftdA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_B_DXCB1473_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 4ftd UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		5 / 9 ASP A 286
GLY A 285
PHE A 292
VAL A 339
THR A 321
 None
 1.28A 4acaB-4ftdA:
undetectable
4acaC-4ftdA:
undetectable		 4acaB-4ftdA:
24.05
4acaC-4ftdA:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRJ_A_RAPA201_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4
SERINE/THREONINE-PRO
TEIN KINASE MTOR)		 4ftd UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 8 LEU A 225
THR A 243
TRP A 241
TYR A 224
 None
 0.98A 4drjB-4ftdA:
undetectable		 4drjB-4ftdA:
12.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 4ftd UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 5 TYR A 272
GLY A 267
ASP A 268
VAL A 339
 None
 1.09A 4nkvD-4ftdA:
undetectable		 4nkvD-4ftdA:
24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA601_1
(SERUM ALBUMIN)		 4ftd UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		5 / 12 LEU A  91
PHE A  67
GLY A  56
SER A  40
LEU A  38
 None
 1.30A 4ot2A-4ftdA:
undetectable		 4ot2A-4ftdA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP1_A_LDPA708_1
(DOPAMINE
TRANSPORTER, ISOFORM
B)		 4ftd UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		5 / 10 PHE A 236
ALA A 270
PHE A 284
SER A 227
GLY A 267
 None
 1.41A 4xp1A-4ftdA:
undetectable		 4xp1A-4ftdA:
24.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_D_ACTD802_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 4ftd UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 6 HIS A 184
ASP A 153
HIS A 181
MET A 200
 None
 1.50A 5m45D-4ftdA:
undetectable		 5m45D-4ftdA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M45_G_ACTG802_0
(ACETONE CARBOXYLASE
ALPHA SUBUNIT)		 4ftd UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		4 / 6 HIS A 184
ASP A 153
HIS A 181
MET A 200
 None
 1.49A 5m45G-4ftdA:
undetectable		 5m45G-4ftdA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 4ftd UNCHARACTERIZED
PROTEIN
(Bacteroides
eggerthii) 		3 / 3 SER A 173
HIS A 184
TYR A 151
 None
 0.96A 5y2tA-4ftdA:
undetectable		 5y2tA-4ftdA:
undetectable